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Genomes and Genes | Jason CysterSummaryAffiliation: University of California Country: USA Publications
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Publications
Sphingosine-1-phosphate and lymphocyte egress from lymphoid organsJason G Cyster
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California 94143 0414, USA
Annu Rev Immunol 30:69-94. 2012..Finally, we examine current understanding of how FTY720, a drug that targets S1P receptors and is approved for the treatment of multiple sclerosis, causes immune suppression...- B cell follicles and antigen encounters of the third kindJason G Cyster
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, USA
Nat Immunol 11:989-96. 2010..This Review will discuss how these factors work together in the lymph node to ensure efficient and persistent exposure of B cells to diverse forms of antigen and thus effective triggering of the humoral response... 
Role of CXCR5 and CCR7 in follicular Th cell positioning and appearance of a programmed cell death gene-1high germinal center-associated subpopulationNicole M Haynes
Howard Hughes Medical Institute, University of California, San Francisco, CA 94143, USA
J Immunol 179:5099-108. 2007....- Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradientsSusan R Schwab
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143 0414, USA
Science 309:1735-9. 2005..We conclude that lymphocyte egress is mediated by S1P gradients that are established by S1P lyase activity and that the lyase may represent a novel immunosuppressant drug target... - Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1Mehrdad Matloubian
Howard Hughes Medical Institute and Department of Microbiology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143 0414, USA
Nature 427:355-60. 2004..These findings establish that S1P1 is essential for lymphocyte recirculation and that it regulates egress from both thymus and peripheral lymphoid organs... - Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cellsTri Giang Phan
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA
Nat Immunol 8:992-1000. 2007.... 
Integrin-dependence of lymphocyte entry into the splenic white pulpCharles G Lo
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, USA
J Exp Med 197:353-61. 2003..These observations suggest that chemokine receptor signaling and the integrins LFA-1 and alpha 4 beta 1 function together to promote lymphocyte transit from the marginal zone into white pulp cords...- Imaging of germinal center selection events during affinity maturationChristopher D C Allen
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
Science 315:528-31. 2007..On the basis of these observations, we propose a model in which competition for T cell help plays a more dominant role in the selection of GC B cells than previously appreciated... - Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropismKenji Kabashima
Howard Hughes Medical Institute HHMI and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, USA
J Exp Med 203:2683-90. 2006.... - Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesisSanjiv A Luther
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0414, USA
J Immunol 169:424-33. 2002.... - T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrowCraig N Jenne
Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
J Exp Med 206:2469-81. 2009..In summary, these findings identify S1P5 as a T-bet-induced gene that is required for NK cell egress from LNs and BM... - Promotion of lymphocyte egress into blood and lymph by distinct sources of sphingosine-1-phosphateRajita Pappu
Cardiovascular Research Institute, University of California, San Francisco, 600 16th Street S472D, San Francisco, CA 94143 2240, USA
Science 316:295-8. 2007..Disruption of compartmentalized S1P signaling is a plausible mechanism by which S1P-receptor-1 agonists function as immunosuppressives... - Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5Christopher D C Allen
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California 94143 0414, USA
Nat Immunol 5:943-52. 2004..In contrast, CXCR5 helped direct cells to the light zone and deficiency in CXCL13 was associated with aberrant light zone localization... - Requirements for follicular exclusion and competitive elimination of autoantigen-binding B cellsEric H Ekland
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
J Immunol 172:4700-8. 2004..These findings characterize the mechanism for follicular exclusion of autoantigen-binding B cells and they indicate that B cells compete for survival by mechanisms that are separate from competition for the follicular niche... - Finding a way out: lymphocyte egress from lymphoid organsSusan R Schwab
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA
Nat Immunol 8:1295-301. 2007..In this review we discuss the body of evidence supporting a model in which lymphocyte egress is promoted by encounter with S1P at exit sites. We relate this model to work examining the effects of S1P receptor agonists on endothelium... - Follicular shuttling of marginal zone B cells facilitates antigen transportGuy Cinamon
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA
Nat Immunol 9:54-62. 2008..Marginal zone-follicle shuttling of marginal zone B cells provides an efficient mechanism for systemic antigen capture and delivery to follicular dendritic cells... - Neural crest-derived pericytes promote egress of mature thymocytes at the corticomedullary junctionMarcus A Zachariah
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, 513 Parnassus Avenue, HSE1001, San Francisco, CA 94143, USA
Science 328:1129-35. 2010..Lymphatic endothelial cell-derived S1P was not required. These studies identify the major thymic egress route and suggest a role for pericytes in promoting reverse transmigration of cells across blood vessel endothelium... - Balanced responsiveness to chemoattractants from adjacent zones determines B-cell positionKarin Reif
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143 0414, USA
Nature 416:94-9. 2002..These findings define the mechanism of B-cell relocalization in response to antigen, and establish that cell position in vivo can be determined by the balance of responsiveness to chemoattractants made in separate but adjacent zones... - Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterningTrung H M Pham
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
J Exp Med 207:17-27. 2010..Our data provide evidence that lymphatic endothelial cells are an in vivo source of S1P required for lymphocyte egress from LNs and Peyer's patches, and suggest a role for S1P in lymphatic vessel maturation... - Sphingosine 1-phosphate receptor 1 promotes B cell localization in the splenic marginal zoneGuy Cinamon
Howard Hughes Medical Institute, Department of Microbiology, University of California San Francisco, 513 Parnassus Avenue, San Francisco, California 94143 0414, USA
Nat Immunol 5:713-20. 2004..These data suggest that marginal zone B cell localization to the marginal zone depends on responsiveness to the blood lysophospholipid S1P, with S1P(1) signaling overcoming the recruiting activity of CXCL13... - Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cellsIrina L Grigorova
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California 94143, USA
Nat Immunol 10:58-65. 2009.... - Intrinsic lymphotoxin-beta receptor requirement for homeostasis of lymphoid tissue dendritic cellsKenji Kabashima
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA
Immunity 22:439-50. 2005..We conclude that LT alpha 1 bet a2 acts on DCs or DC precursors to promote DC homeostasis, and we suggest that DC proliferation is an important pathway for locally maintaining these cells in the steady state... - Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transitCharles G Lo
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
J Exp Med 201:291-301. 2005..We propose that cyclical ligand-induced modulation of S1P(1) on circulating lymphocytes contributes to establishing their lymphoid organ transit time... - CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph nodeTakaharu Okada
Department of Microbiology and Immunology and Howard Hughes Medical Institute, University of California San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
J Immunol 178:2973-8. 2007..These results reveal a role for CCR7 in promoting T cell migration within lymphoid organ T zones, and they suggest the additional involvement of novel Gi-coupled receptors in promoting T cell motility at these sites... - S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egressTrung H M Pham
Howard Hughes Medical Institute, University of California, San Francisco, CA 94143, USA
Immunity 28:122-33. 2008..Furthermore, by simultaneously upregulating S1P1 and downregulating CCR7, T cells that have divided multiple times switch to a state favoring egress over retention... - Finding the right niche: B-cell migration in the early phases of T-dependent antibody responsesJoão Pedro Pereira
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, 94143, USA
Int Immunol 22:413-9. 2010..In this review, we discuss current understanding of the roles played by chemokines, S1P and EBI2 in the migration events that underlie humoral immune responses... - Cannabinoid receptor 2 mediates the retention of immature B cells in bone marrow sinusoidsJoao P Pereira
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, USA
Nat Immunol 10:403-11. 2009..Our findings identify unique requirements for the retention of B cells in the bone marrow sinusoidal niche and suggest involvement of CB2 in the generation of the B cell repertoire... - Specifying the patterns of immune cell migrationJason G Cyster
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
Novartis Found Symp 281:54-61; discussion 61-4, 208-9. 2007..We have recently identified CD69 as a regulator of SIP1 and controller of lymphocyte egress. Current molecular understanding of the lymphocyte egress process will be discussed... - Germinal-center organization and cellular dynamicsChristopher D C Allen
Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, CA 94143 0414, USA
Immunity 27:190-202. 2007.... - Follicular dendritic cell networks of primary follicles and germinal centers: phenotype and functionChristopher D C Allen
Howard Hughes Medical Institute and Department of Microbiology and Immunology, 513 Parnassus Avenue, Box 0414, University of California, San Francisco, CA 94143 0414, USA
Semin Immunol 20:14-25. 2008..We will then discuss current understanding of how they help support the B cell immune response... - A role for S1P and S1P1 in immature-B cell egress from mouse bone marrowJoão Pedro Pereira
Department of Microbiology and Immunology, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 5:e9277. 2010..We conclude that the S1P1-S1P pathway contributes to egress of immature-B cells from BM, and that this mechanism is partially redundant with other undefined pathways... - CD69 suppresses sphingosine 1-phosophate receptor-1 (S1P1) function through interaction with membrane helix 4Alexander J Bankovich
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California 94143, USA
J Biol Chem 285:22328-37. 2010.... - CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organsLawrence R Shiow
Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, California 94143, USA
Nature 440:540-4. 2006..These observations indicate that CD69 forms a complex with and negatively regulates S1P1 and that it functions downstream of IFN-alpha/beta, and possibly other activating stimuli, to promote lymphocyte retention in lymphoid organs... - Lymphoid organ development and cell migrationJason G Cyster
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143 0414, USA
Immunol Rev 195:5-14. 2003.... - CCR2-dependent trafficking of F4/80dim macrophages and CD11cdim/intermediate dendritic cells is crucial for T cell recruitment to lungs infected with Mycobacterium tuberculosisWendy Peters
Gladstone Institute of Cardiovascular Disease, PO Box 419100, San Francisco, CA 94141, USA
J Immunol 172:7647-53. 2004..Further investigation revealed a critical role for CCR2 in the recruitment of F4/80(dim) macrophages and CD11c(dim/intermediate) DCs to the infected lung... - Homing of antibody secreting cellsJason G Cyster
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143 0414, USA
Immunol Rev 194:48-60. 2003..The function of CCR9 and CCR10 in IgA ASC homing and contributions made by integrins and lectins are also discussed... - Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homingKarin Reif
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA
J Immunol 173:2236-40. 2004..These observations establish that p110gamma and p110delta function in lymphocyte chemotaxis, and show differential roles for PI3K family members in B and T cell migration... - Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organsJason G Cyster
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, California 94143 0414, USA
Annu Rev Immunol 23:127-59. 2005..Here, we review the steps associated with the initiation of adaptive immune responses in secondary lymphoid organs, highlighting the roles of chemokines and S1P... - CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunityK Mark Ansel
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, CA 94143, USA
Immunity 16:67-76. 2002..These findings provide insight into the mechanism of B1 cell homing and establish a critical role for B1 cell compartmentalization in the production of natural antibodies and for body cavity immunity... - Integrin-mediated long-term B cell retention in the splenic marginal zoneTheresa T Lu
Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, 513 Parnassus Avenue, San Francisco, CA 94143, USA
Science 297:409-12. 2002..These studies identify key requirements for MZ B cell localization and establish a role for integrins in peripheral lymphoid tissue compartmentalization... - B cell migration and interactions in the early phase of antibody responsesTakaharu Okada
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143 0414, USA
Curr Opin Immunol 18:278-85. 2006..Taken together, these studies have provided a more detailed map of the steps involved in B cell migration to encounter antigen and helper T cells early during the adaptive immune response... - Chemokine requirements for B cell entry to lymph nodes and Peyer's patchesTakaharu Okada
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143, USA
J Exp Med 196:65-75. 2002..These findings establish the principal chemokine and chemokine receptor requirements for B cell entry to lymph nodes and Peyer's patches... - Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node developmentSanjiv A Luther
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, 94143, USA
J Exp Med 197:1191-8. 2003..These findings indicate that CXCL13 and CCR7 ligands promote accumulation of CD4+ CD3- IL-7R alpha hi cells, delivering IL-7R alpha-dependent LT alpha 1 beta 2 signals critical for LN development... - The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiencyLawrence R Shiow
Howard Hughes Medical Institute, University of California San Francisco, San Francisco, California 94143, USA
Nat Immunol 9:1307-15. 2008.... - EBI2 mediates B cell segregation between the outer and centre follicleJoao P Pereira
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California San Francisco, California 94143, USA
Nature 460:1122-6. 2009.... - Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFFRobin Lesley
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143 USA
Immunity 20:441-53. 2004..These findings indicate that under conditions where BAFF levels are elevated, autoantigen-engaged cells will be rescued from rapid competitive elimination, predisposing to the development of autoimmune disease... - Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cellsTakaharu Okada
Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, California, USA
PLoS Biol 3:e150. 2005..These findings provide evidence of lymphocyte chemotaxis in vivo, and they begin to define the spatiotemporal cellular dynamics associated with T cell-dependent antibody responses... - Detection of a sulfotransferase (HEC-GlcNAc6ST) in high endothelial venules of lymph nodes and in high endothelial venule-like vessels within ectopic lymphoid aggregates: relationship to the MECA-79 epitopeAnnette Bistrup
Department of Anatomy, University of California, San Francisco, California 94143 0452, USA
Am J Pathol 164:1635-44. 2004..Analysis of the progeny of RIP-BLC by HEC-GlcNAc6ST-null mice establishes that the enzyme is responsible for the MECA-79 defined luminal ligands... - Chemorepulsion and thymocyte emigrationJason G Cyster
Howard Hughes Medical Institute, University of California-San Francisco, 513 Parnassus Ave, San Francisco, CA 94143-0414, USA
J Clin Invest 109:1011-2. 2002 - A p38 MAPK-MEF2C pathway regulates B-cell proliferationDustin Khiem
Cardiovascular Research Institute and Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158 2517, USA
Proc Natl Acad Sci U S A 105:17067-72. 2008..p38 directly phosphorylates MEF2C via three residues in the C-terminal transactivation domain, establishing MEF2C as a direct transcriptional effector of BCR signaling via p38 MAPK... - Visualizing B cell capture of cognate antigen from follicular dendritic cellsKazuhiro Suzuki
Howard Hughes Medical Institute and Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94143, USA
J Exp Med 206:1485-93. 2009.... - The CDM protein DOCK2 in lymphocyte migrationKarin Reif
Howard Hughes Medical Institute, Dept of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143 0414, USA
Trends Cell Biol 12:368-73. 2002..Here, we review the role of DOCK2 in lymphocyte homing to lymphoid tissues and discuss recent findings for other CDM family molecules that provide a basis for understanding how DOCK2 might function in lymphocytes... - TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosisThomas T Chen
Veterans Administration Medical Center, San Francisco, CA 94121, USA
J Exp Med 202:955-65. 2005..This is the first identification of a receptor for ferritin and reveals a new role for TIM-2... - Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletionLawrence R Shiow
Biomedical Sciences Graduate Program, Department of Microbiology and Immunology, University of California San Francisco, San Francisco, CA 94143 0519, USA
Clin Immunol 131:24-30. 2009..This case highlights the first link between actin cytoskeleton regulation and SCID... - Naive CD4 T cells constitutively express CD40L and augment autoreactive B cell survivalRobin Lesley
Howard Hughes Medical Institute and Department of Microbiology and Immunology, and Biomedical Sciences Graduate Program, University of California, San Francisco, CA 94143 7242, USA
Proc Natl Acad Sci U S A 103:10717-22. 2006..We propose that constitutive CD40L expression by naive CD4 T cells influences the composition of the B cell repertoire and may also affect the homeostasis of other cell types such as regulatory T cells in lymphoid organs... - Visualization of the genesis and fate of isotype-switched B cells during a primary immune responseKathryn A Pape
Department of Microbiology and Center for Immunology, University of Minnesota Medical School, MMC334, 420 Delaware St S E, Minneapolis, MN 55455, USA
J Exp Med 197:1677-87. 2003..Antigen-experienced IgM B cells were rarely found in GCs, indicating that these cells switched rapidly after entering GCs or did not persist in this environment... - Lymph node chemokines promote sustained T lymphocyte motility without triggering stable integrin adhesiveness in the absence of shear forcesEilon Woolf
Department of Immunology, The Weizmann Institute of Science, Rehovot 76100, Israel
Nat Immunol 8:1076-85. 2007..Thus, lymph node chemokines that promote motility and strongly activate lymphocyte integrins under shear forces fail to stimulate stable integrin adhesiveness in extravascular shear-free environments... - Traffic patterns of B cells and plasma cellsJason G Cyster
Department of Microbiology and Immunology, University of California, San Francisco 94143, USA
Adv Exp Med Biol 512:35-41. 2002 - FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier functionVolker Brinkmann
Transplantation and Immunology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Am J Transplant 4:1019-25. 2004..The available data establish S1P(1) as a key target for FTY720, and further point to therapeutically relevant effects of the drug on lymphocytes and vascular endothelium... - Spontaneous class switching and B cell hyperactivity increase autoimmunity against intracellular self antigen in Lyn-deficient miceKarlee Silver
Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford, UK
Eur J Immunol 36:2920-7. 2006..Under these circumstances, spontaneous activation of hyperactive B cells leads to isotype switching and the development of high titres of IgG autoantibodies against intracellular proteins... - Initiation of cellular organization in lymph nodes is regulated by non-B cell-derived signals and is not dependent on CXC chemokine ligand 13Tom Cupedo
Department of Molecular Cell Biology and Immunology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
J Immunol 173:4889-96. 2004.... - Overview of the Alliance for Cellular SignalingAlfred G Gilman
Department of Pharmacology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Nature 420:703-6. 2002..One goal is to catalyse complementary research in individual laboratories; to facilitate this, all alliance data are freely available for use by the entire research community... - Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cellsAlexander Link
Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland
Nat Immunol 8:1255-65. 2007..Our data suggest that lymph nodes and T zone fibroblastic reticular cells have a key function in naive CD4(+) and CD8(+) T cell homeostasis by providing a limited reservoir of survival factors... - Langerhans cells renew in the skin throughout life under steady-state conditionsMiriam Merad
Department of Pathology, Stanford University School of Medicine, Stanford, CA 94304, USA
Nat Immunol 3:1135-41. 2002..These data indicate that under steady-state conditions, LCs are maintained locally, but inflammatory changes in the skin result in their replacement by blood-borne LC progenitors...
Research Grants
- Beta Lymphocyte Migration and HomeostasisJason Cyster; Fiscal Year: 2007..abstract_text> ..
- Chemokines and Lymphoid Tissue Organization and FunctionJason Cyster; Fiscal Year: 2007..abstract_text> ..
- Cellular and Genetic Analysis of Lymphocyte EgressJason Cyster; Fiscal Year: 2007..The information obtained through these studies should point to new targets for the development of immunomodulatory molecules. ..
- Chemokines and Lymphoid Tissue Organization and FunctionJason Cyster; Fiscal Year: 2009....
- Chemokines and Lymphoid Tissue Organization and FunctionJason G Cyster; Fiscal Year: 2010....
- B LYMPHOCYTE MIGRATION AND HOMEOSTASISJason Cyster; Fiscal Year: 2001..As well as improving our understanding of normal B-cell function, these studies are likely to provide important insight into defects in B-cell trafficking and homeostasis that contribute to autoimmunity or immunodeficiency. ..
- BLC AND BLR1 AND IMMUNE FUNCTION AND DYSFUNCTIONJason Cyster; Fiscal Year: 2003....
- Cellular and Genetic Analysis of Lymphocyte EgressJason G Cyster; Fiscal Year: 2010..The information obtained through these studies should point to new targets for the development of immunomodulatory molecules. ..