M Cushman

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. ncbi request reprint The association of vitamin K status with warfarin sensitivity at the onset of treatment
    M Cushman
    Department of Medicine, University of Vermont, 208 South Park Drive, Suite 2, Colchester, VT 05446, USA
    Br J Haematol 112:572-7. 2001
  2. ncbi request reprint Post-menopausal hormone therapy and concentrations of protein C and antithrombin in elderly women
    M Cushman
    Department of Medicine, University of Vermont, Burlington, VT, USA
    Br J Haematol 114:162-8. 2001
  3. ncbi request reprint Hormone replacement therapy, inflammation, and hemostasis in elderly women
    M Cushman
    Departments of Medicine, University of Vermont, Burlington, USA
    Arterioscler Thromb Vasc Biol 19:893-9. 1999
  4. ncbi request reprint Effect of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Study
    M Cushman
    Departments of Medicine, and Biochemistry, University of Vermont, Burlington, VT 05446, USA
    Circulation 100:717-22. 1999
  5. ncbi request reprint Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the Cardiovascular Health Study
    N A Zakai
    Department of Medicine, Brown University and Boston University, Providence, RI, USA
    J Thromb Haemost 5:1128-35. 2007
  6. ncbi request reprint Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project
    R P Tracy
    University of Vermont, Colchester 05446, USA
    Arterioscler Thromb Vasc Biol 17:1121-7. 1997
  7. ncbi request reprint Lifetime smoking exposure affects the association of C-reactive protein with cardiovascular disease risk factors and subclinical disease in healthy elderly subjects
    R P Tracy
    Department of Pathology and Biochemistry, University of Vermont, Colchester 05446, USA
    Arterioscler Thromb Vasc Biol 17:2167-76. 1997
  8. ncbi request reprint Tamoxifen and cardiac risk factors in healthy women: Suggestion of an anti-inflammatory effect
    M Cushman
    Department of Medicine and Pathology, University of Vermont, Burlington 05446, USA
    Arterioscler Thromb Vasc Biol 21:255-61. 2001
  9. pmc Association of endothelial and oxidative stress with metabolic syndrome and subclinical atherosclerosis: multi-ethnic study of atherosclerosis
    D Vaidya
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Eur J Clin Nutr 65:818-25. 2011
  10. pmc Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study
    N A Zakai
    Department of Medicine, University of Vermont, Burlington, VT, USA
    J Thromb Haemost 9:267-74. 2011

Collaborators

Detail Information

Publications30

  1. ncbi request reprint The association of vitamin K status with warfarin sensitivity at the onset of treatment
    M Cushman
    Department of Medicine, University of Vermont, 208 South Park Drive, Suite 2, Colchester, VT 05446, USA
    Br J Haematol 112:572-7. 2001
    ..05). We concluded that dietary and biochemical measures of vitamin K status were associated with early warfarin sensitivity...
  2. ncbi request reprint Post-menopausal hormone therapy and concentrations of protein C and antithrombin in elderly women
    M Cushman
    Department of Medicine, University of Vermont, Burlington, VT, USA
    Br J Haematol 114:162-8. 2001
    ..This study extends previous observations to older women, the group at highest risk of venous thromboembolism. Studies of HRT-induced alterations in anticoagulant function in relation to the occurrence of thrombosis with HRT are required...
  3. ncbi request reprint Hormone replacement therapy, inflammation, and hemostasis in elderly women
    M Cushman
    Departments of Medicine, University of Vermont, Burlington, USA
    Arterioscler Thromb Vasc Biol 19:893-9. 1999
    ..Associations with hemostasis markers indicated no association with evidence of procoagulation and a possible association with increased fibrinolytic activity...
  4. ncbi request reprint Effect of postmenopausal hormones on inflammation-sensitive proteins: the Postmenopausal Estrogen/Progestin Interventions (PEPI) Study
    M Cushman
    Departments of Medicine, and Biochemistry, University of Vermont, Burlington, VT 05446, USA
    Circulation 100:717-22. 1999
    ..Because higher levels of inflammation factors predict vascular disease outcomes, the effect of hormones on these factors is of interest...
  5. ncbi request reprint Inflammation and hemostasis biomarkers and cardiovascular risk in the elderly: the Cardiovascular Health Study
    N A Zakai
    Department of Medicine, Brown University and Boston University, Providence, RI, USA
    J Thromb Haemost 5:1128-35. 2007
    ..There are few studies of inflammation and hemostasis biomarkers and cardiovascular disease risk (CVD) in older adults...
  6. ncbi request reprint Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project
    R P Tracy
    University of Vermont, Colchester 05446, USA
    Arterioscler Thromb Vasc Biol 17:1121-7. 1997
    ..7 (CI = 1.10 to 6.60). In conclusion, CRP was associated with incident events in the elderly, especially in those with subclinical disease at baseline...
  7. ncbi request reprint Lifetime smoking exposure affects the association of C-reactive protein with cardiovascular disease risk factors and subclinical disease in healthy elderly subjects
    R P Tracy
    Department of Pathology and Biochemistry, University of Vermont, Colchester 05446, USA
    Arterioscler Thromb Vasc Biol 17:2167-76. 1997
    ..Moreover, exposure to smoking affects the relation of CRP to these other factors...
  8. ncbi request reprint Tamoxifen and cardiac risk factors in healthy women: Suggestion of an anti-inflammatory effect
    M Cushman
    Department of Medicine and Pathology, University of Vermont, Burlington 05446, USA
    Arterioscler Thromb Vasc Biol 21:255-61. 2001
    ..These findings are in contrast to recent reports of increased C-reactive protein associated with postmenopausal estrogen. The potential for beneficial cardiovascular effects of tamoxifen in healthy women is suggested...
  9. pmc Association of endothelial and oxidative stress with metabolic syndrome and subclinical atherosclerosis: multi-ethnic study of atherosclerosis
    D Vaidya
    Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Eur J Clin Nutr 65:818-25. 2011
    ..We examined whether the association of MetS with subclinical atherosclerosis is explained by biomarkers of endothelial damage and oxidative stress...
  10. pmc Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study
    N A Zakai
    Department of Medicine, University of Vermont, Burlington, VT, USA
    J Thromb Haemost 9:267-74. 2011
    ..Thrombosis and inflammation are critical in stroke etiology, but associations of coagulation and inflammation gene variants with stroke, and particularly factor VII levels, are inconclusive...
  11. ncbi request reprint Evaluation of very low-dose subcutaneous vitamin K during postoperative warfarin therapy
    C J Possidente
    Department of Pharmacotherapy, Fletcher Allen Health Care, Burlington, Vermont, USA
    Pharmacotherapy 21:295-300. 2001
    ..Investigations in other populations and assessment of the effect of low-dose SCVK on postoperative bleeding are indicated...
  12. pmc Risk factors for peripheral venous disease resemble those for venous thrombosis: the San Diego Population Study
    M Cushman
    Department of Medicine, University of Vermont, Burlington, VT, USA
    J Thromb Haemost 8:1730-5. 2010
    ..Clinically silent deep vein thrombosis (DVT) is common and may cause chronic venous disease that resembles post-thrombotic syndrome...
  13. ncbi request reprint Hormonal factors and risk of recurrent venous thrombosis: the prevention of recurrent venous thromboembolism trial
    M Cushman
    Department of Medicine, University of Vermont, Burlington, VT 05446, USA
    J Thromb Haemost 4:2199-203. 2006
    ..In some but not all studies, men with venous thrombosis had a higher risk of recurrence than women. Information on women with initial hormone-related thrombosis is scant...
  14. ncbi request reprint Effects of estrogen and selective estrogen receptor modulators on hemostasis and inflammation: potential differences among drugs
    M Cushman
    Department of Medicine, University of Vermont, Colchester 05446, USA
    Ann N Y Acad Sci 949:175-80. 2001
    ..From the vascular perspective, future studies need to focus on interactions of treatment with these biochemical parameters and their genetic correlates in order to define low- or high-risk subgroups for intervention with these therapies...
  15. ncbi request reprint Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease
    P M Ridker
    Department of Medicine, Brigham and Women s Hospital, Boston, Mass 02115 1204, USA
    Circulation 97:425-8. 1998
    ..Whether increased levels of CRP are also associated with the development of symptomatic peripheral arterial disease (PAD) is unknown...
  16. pmc Tissue factor pathway inhibitor, vascular risk factors and subclinical atherosclerosis: the Multi-Ethnic Study of Atherosclerosis
    C T Mitchell
    Department of Medicine, University of Vermont, Burlington, VT 05446, USA
    Atherosclerosis 207:277-83. 2009
    ..Tissue factor pathway inhibitor (TFPI) is an endothelial membrane-associated anticoagulant protein. Higher circulating levels might reflect endothelial damage...
  17. ncbi request reprint Trousseau's syndrome treated with long-term subcutaneous lepirudin (case report and review of the literature)
    A C Andreescu
    Department of Medicine, University of Vermont, Burlington 05401, USA
    J Thromb Thrombolysis 11:33-7. 2001
    ..To our knowledge this case represents the longest reported use of subcutaneous lepirudin...
  18. doi request reprint Venous thrombosis risk assessment in medical inpatients: the medical inpatients and thrombosis (MITH) study
    N A Zakai
    University of Vermont College of Medicine and Fletcher Allen Health Care, Colchester, VT 05446, USA
    J Thromb Haemost 11:634-41. 2013
    ..We sought to define the risk factors present at admission for venous thromboembolism (VTE) in medical inpatients and develop a risk model for clinical use...
  19. pmc Statin therapy and levels of hemostatic factors in a healthy population: the Multi-Ethnic Study of Atherosclerosis
    N B Adams
    Department of Medicine, University of Vermont, Burlington, VT 05446, USA
    J Thromb Haemost 11:1078-84. 2013
    ..HMG-CoA reductase inhibitors (statins) reduce the risk of venous thromboembolism (VTE) in healthy people. Statins reduce levels of inflammation biomarkers; however, the mechanism for the reduction in VTE risk is unknown...
  20. ncbi request reprint Importance of heart failure with preserved systolic function in patients > or = 65 years of age. CHS Research Group. Cardiovascular Health Study
    D W Kitzman
    Department of Medicine, Wake Forest University School of Medicine, Winston-Salem, North Carolina 27157-1045, USA
    Am J Cardiol 87:413-9. 2001
    ..The finding that a large proportion of elderly with CHF have preserved LV systolic function is important because there is a paucity of data to guide management in this dominant subset...
  21. ncbi request reprint Risk factors for venous thrombosis in medical inpatients: validation of a thrombosis risk score
    N A Zakai
    Department of Medicine, University of Vermont College of Medicine and Fletcher Allen Health Care, Burlington, VT 05446, USA
    J Thromb Haemost 2:2156-61. 2004
    ..The occurrence of and risk factors for venous thrombosis (VT) complicating hospital admission in unselected medical inpatients have not been widely studied. PATIENTS and..
  22. ncbi request reprint Subclinical atherosclerosis and the risk of future venous thrombosis in the Cardiovascular Health Study
    P B van der Hagen
    Department of Medicine, University of Vermont, Burlington, 05446, USA
    J Thromb Haemost 4:1903-8. 2006
    ..Recent reports have suggested an association of atherosclerosis with risk of venous thrombosis...
  23. ncbi request reprint D-dimer, factor VIII coagulant activity, low-intensity warfarin and the risk of recurrent venous thromboembolism
    S Shrivastava
    Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital, Boston, MA, USA
    J Thromb Haemost 4:1208-14. 2006
    ..Elevated plasma D-dimer and factor VIII coagulant activity (FVIIIc) may be associated with the risk of recurrent venous thromboembolism (VTE)...
  24. ncbi request reprint Factor VII coagulant activity, factor VII -670A/C and -402G/A polymorphisms, and risk of venous thromboembolism
    A R Folsom
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    J Thromb Haemost 5:1674-8. 2007
    ..Our Longitudinal Investigation of Thromboembolism Etiology (LITE) had, in contrast, reported an independent, increased risk of VTE after 7.8 years of follow-up for those with high baseline levels of FVII:C...
  25. ncbi request reprint Associations of plasma fibrinogen levels with established cardiovascular disease risk factors, inflammatory markers, and other characteristics: individual participant meta-analysis of 154,211 adults in 31 prospective studies: the fibrinogen studies collab
    S Kaptoge
    Am J Epidemiol 166:867-79. 2007
    ..These findings substantially advance understanding of the correlates and possible determinants of fibrinogen levels...
  26. ncbi request reprint ABO blood group, other risk factors and incidence of venous thromboembolism: the Longitudinal Investigation of Thromboembolism Etiology (LITE)
    T Ohira
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN 55454 1015, USA
    J Thromb Haemost 5:1455-61. 2007
    ..Numerous case-control studies have reported higher prevalence of non-O blood type among venous thromboembolism (VTE) patients than controls, but potential mechanisms or effect modifiers for the association are not fully established...
  27. ncbi request reprint Plasma fibrinogen level and the risk of major cardiovascular diseases and nonvascular mortality: an individual participant meta-analysis
    John Danesh
    Department of Public Health and Primary Care, University of Cambridge, Cambridge, England
    JAMA 294:1799-809. 2005
    ..Plasma fibrinogen levels may be associated with the risk of coronary heart disease (CHD) and stroke...
  28. ncbi request reprint Prospective study of subclinical atherosclerosis as a risk factor for venous thromboembolism
    L M Reich
    Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, 55454 1015, USA
    J Thromb Haemost 4:1909-13. 2006
    ..Whether atherosclerotic disease predisposes to venous thrombosis is uncertain...
  29. ncbi request reprint Prospective study of the A455V polymorphism in the thrombomodulin gene, plasma thrombomodulin, and incidence of venous thromboembolism: the LITE Study
    N Aleksic
    Division of Hematology, University of Texas Medical School, Houston, TX 77030, USA
    J Thromb Haemost 1:88-94. 2003
    ..There were no associations of age-adjusted sTM or TMA455V genotype with overall venous thromboembolism or with thrombosis in any subtype of venous thromboembolism...
  30. ncbi request reprint Plasma hemostatic factors and endothelial markers in four racial/ethnic groups: the MESA study
    P L Lutsey
    Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA
    J Thromb Haemost 4:2629-35. 2006
    ..Hemostatic factors and endothelial markers may play some role in racial/ethnic differences in cardiovascular disease (CVD) rates. However, little information exists on hemostatic factors and endothelial markers across racial/ethnic groups...