J D Curb

Summary

Affiliation: University of Hawaii
Country: USA

Publications

  1. ncbi request reprint Serum lipid effects of a high-monounsaturated fat diet based on macadamia nuts
    J D Curb
    Department of Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu 96817, USA
    Arch Intern Med 160:1154-8. 2000
  2. ncbi request reprint Outcomes ascertainment and adjudication methods in the Women's Health Initiative
    J David Curb
    Department of Geriatric Medicine, University of Hawaii, Honolulu, HI 96813, USA
    Ann Epidemiol 13:S122-8. 2003
  3. ncbi request reprint C-reactive protein and the future risk of thromboembolic stroke in healthy men
    J David Curb
    Pacific Health Research Institute, Honolulu, Hawaii 96813, USA
    Circulation 107:2016-20. 2003
  4. ncbi request reprint Impaired glucose tolerance, diabetes, and cardiovascular disease risk factor profiles in the elderly. The Honolulu Heart Program
    B L Rodriguez
    Division of Clinical Epidemiology, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu 96817, USA
    Diabetes Care 19:587-90. 1996
  5. ncbi request reprint Age-related changes in stroke risk in men with hypertension and normal blood pressure
    J D Curb
    John A Burns School of Medicine, University of Hawaii at Manoa, USA
    Stroke 27:819-24. 1996
  6. pmc Association of fibrinogen with Parkinson disease in elderly Japanese-American men: a prospective study
    K T Wong
    Department of Public Health Sciences, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA
    Neuroepidemiology 34:50-4. 2010
  7. ncbi request reprint Plasma fibrinogen and coronary heart disease in elderly Japanese-American men
    D S Sharp
    Honolulu Epidemiology Research Section, National Heart, Lung, and Blood Institute, Hawaii, Honolulu 96817, USA
    Arterioscler Thromb Vasc Biol 16:262-8. 1996
  8. ncbi request reprint Hyperinsulinemia and cardiovascular disease in elderly men: the Honolulu Heart Program
    C M Burchfiel
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Honolulu, HI, USA
    Arterioscler Thromb Vasc Biol 18:450-7. 1998
  9. ncbi request reprint Glucose intolerance and 23-year risk of coronary heart disease and total mortality: the Honolulu Heart Program
    B L Rodriguez
    Department of Medicine, University of Hawaii at Manoa, USA
    Diabetes Care 22:1262-5. 1999
  10. ncbi request reprint Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study
    I J Schatz
    Clinical Epidemiology and Geriatrics Division, Department of Medicine, John A Bums School of Medicine, University of Hawaii at Manoa, 1356 Lusitana Street, 7th Floor, Honolulu, HI 96813 2427, USA
    Lancet 358:351-5. 2001

Detail Information

Publications84

  1. ncbi request reprint Serum lipid effects of a high-monounsaturated fat diet based on macadamia nuts
    J D Curb
    Department of Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu 96817, USA
    Arch Intern Med 160:1154-8. 2000
    ..Recent studies have identified potential beneficial effects of eating nuts, most of which have substantial amounts of monounsaturated fats. Macadamia nuts are 75% fat by weight, 80% of which is monounsaturated...
  2. ncbi request reprint Outcomes ascertainment and adjudication methods in the Women's Health Initiative
    J David Curb
    Department of Geriatric Medicine, University of Hawaii, Honolulu, HI 96813, USA
    Ann Epidemiol 13:S122-8. 2003
  3. ncbi request reprint C-reactive protein and the future risk of thromboembolic stroke in healthy men
    J David Curb
    Pacific Health Research Institute, Honolulu, Hawaii 96813, USA
    Circulation 107:2016-20. 2003
    ..Whether associations are altered in the presence of other risk factors is unclear. The purpose of this study was to additionally assess the relation between CRP and TE stroke...
  4. ncbi request reprint Impaired glucose tolerance, diabetes, and cardiovascular disease risk factor profiles in the elderly. The Honolulu Heart Program
    B L Rodriguez
    Division of Clinical Epidemiology, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu 96817, USA
    Diabetes Care 19:587-90. 1996
    ....
  5. ncbi request reprint Age-related changes in stroke risk in men with hypertension and normal blood pressure
    J D Curb
    John A Burns School of Medicine, University of Hawaii at Manoa, USA
    Stroke 27:819-24. 1996
    ..Stroke is a major contributor to total morbidity and mortality in older individuals, and hypertension is an important risk factor for stroke. Relatively few data exist on whether this relationship changes with age...
  6. pmc Association of fibrinogen with Parkinson disease in elderly Japanese-American men: a prospective study
    K T Wong
    Department of Public Health Sciences, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA
    Neuroepidemiology 34:50-4. 2010
    ..The purpose of this prospective study was to examine whether fibrinogen level is associated with Parkinson disease (PD) for both prevalent and incident cases...
  7. ncbi request reprint Plasma fibrinogen and coronary heart disease in elderly Japanese-American men
    D S Sharp
    Honolulu Epidemiology Research Section, National Heart, Lung, and Blood Institute, Hawaii, Honolulu 96817, USA
    Arterioscler Thromb Vasc Biol 16:262-8. 1996
    ..Because of the cross-sectional nature of this study, it is not possible to distinguish whether the observed relation of fibrinogen to prevalent CHD is causal or whether it represents a marker of active and progressive disease...
  8. ncbi request reprint Hyperinsulinemia and cardiovascular disease in elderly men: the Honolulu Heart Program
    C M Burchfiel
    Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Honolulu, HI, USA
    Arterioscler Thromb Vasc Biol 18:450-7. 1998
    ....
  9. ncbi request reprint Glucose intolerance and 23-year risk of coronary heart disease and total mortality: the Honolulu Heart Program
    B L Rodriguez
    Department of Medicine, University of Hawaii at Manoa, USA
    Diabetes Care 22:1262-5. 1999
    ..The associations between glucose intolerance measured at the study entry date and the 23-year incidence of coronary heart disease (CHD), CHD mortality, and total mortality were examined at the Honolulu Heart Program...
  10. ncbi request reprint Cholesterol and all-cause mortality in elderly people from the Honolulu Heart Program: a cohort study
    I J Schatz
    Clinical Epidemiology and Geriatrics Division, Department of Medicine, John A Bums School of Medicine, University of Hawaii at Manoa, 1356 Lusitana Street, 7th Floor, Honolulu, HI 96813 2427, USA
    Lancet 358:351-5. 2001
    ..To investigate these discrepancies, we did a longitudinal assessment of changes in both lipid and serum cholesterol concentrations over 20 years, and compared them with mortality...
  11. ncbi request reprint Orthostatic hypotension predicts mortality in elderly men: the Honolulu Heart Program
    K H Masaki
    Honolulu Heart Program, Kuakini Medical Center, Honolulu, Hawaii, USA
    Circulation 98:2290-5. 1998
    ..Population-based data are unavailable concerning the predictive value of orthostatic hypotension on mortality in ambulatory elderly patients, particularly minority groups...
  12. ncbi request reprint Distribution and correlates of lipids and lipoproteins in elderly Japanese-American men. The Honolulu Heart Program
    C M Burchfiel
    Honolulu Epidemiology Research Unit, National Heart, Lung, and Blood Institute, Hawaii, Honolulu, USA
    Arterioscler Thromb Vasc Biol 16:1356-64. 1996
    ..These analyses also identify several modifiable factors that may favorably influence lipid and lipoprotein levels in the elderly...
  13. ncbi request reprint The insulin resistance syndrome in native Hawaiians. Native Hawaiian Health Research (NHHR) Project
    M K Mau
    Pacific Biomedical Research Center, Department of Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, USA
    Diabetes Care 20:1376-80. 1997
    ..To investigate whether fasting hyperinsulinemia is associated with a clustering of cardiovascular disease (CVD) risk factors, manifesting as the insulin resistance syndrome (IRS), in a population of native Hawaiians...
  14. ncbi request reprint Fish intake may limit the increase in risk of coronary heart disease morbidity and mortality among heavy smokers. The Honolulu Heart Program
    B L Rodriguez
    John A Burns School of Medicine, University of Hawaii at Manoa, Hawaii, USA
    Circulation 94:952-6. 1996
    ..We explored this fish-smoking interaction using coronary heart disease (CHD) incidence and mortality as the outcome...
  15. ncbi request reprint Peripheral artery disease and cardiovascular risk factors in the elderly. The Honolulu Heart Program
    J D Curb
    Division of Clinical Epidemiology, John A Burns School of Medicine, University of Hawaii at Manoa, USA
    Arterioscler Thromb Vasc Biol 16:1495-500. 1996
    ..2. The OR associated with hypertension was 1.8 and that for smoking, 2.9 (P < .05 for all ORs). These findings are consistent with ABI being a marker for generalized atherosclerotic disease in old and very old Japanese American men...
  16. ncbi request reprint Mean red cell volume as a correlate of blood pressure
    D S Sharp
    Honolulu Epidemiology Research Unit, Division of Epidemiology and Clinical Applications, National Heart, Lung, and Blood Institute, Honolulu, Hawaii, USA
    Circulation 93:1677-84. 1996
    ..Epidemiological studies show no relation or higher MCVs. In the present study of elderly men (71 to 93 years of age) of the Honolulu Heart Program, elements of both findings are confirmed...
  17. ncbi request reprint The relationship of psychosocial factors to total mortality among older Japanese-American men: the Honolulu Heart Program
    C D Ceria
    University of Hawaii, School of Nursing and Dental Hygiene, Honolulu, Hawaii, USA
    J Am Geriatr Soc 49:725-31. 2001
    ..CONCLUSIONS: Our findings suggest that social networks were significantly independently associated with 6-year all-cause mortality in this cohort of older Japanese-American men. Social interventions in old age may reduce early mortality...
  18. ncbi request reprint Plasma fibrinogen as a predictor of total and cause-specific mortality in elderly Japanese-American men
    K Yano
    Honolulu Heart Program, Kuakini Medical Center, Honolulu, Hawaii, USA
    Arterioscler Thromb Vasc Biol 21:1065-70. 2001
    ..We conclude that plasma fibrinogen is an independent risk factor for mortality from a broad spectrum of diseases in elderly men and that this universal effect of fibrinogen on mortality may be mediated partly through inflammation...
  19. ncbi request reprint Prevalence of overweight and central adiposity is associated with percentage of indigenous ancestry among native Hawaiians
    A Grandinetti
    Pacific Biomedical Research Center, Department of Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, USA
    Int J Obes Relat Metab Disord 23:733-7. 1999
    ..To assess the relationship of percentage of indigenous ancestry with body mass index (BMI) and waist to hip ratio (WHR) among Native Hawaiians...
  20. ncbi request reprint Association of coffee and caffeine intake with the risk of Parkinson disease
    G W Ross
    Department of Veterans Affairs, Honolulu 151, PO Box 50188, Honolulu, HI 96850, USA
    JAMA 283:2674-9. 2000
    ..The projected expansion in the next several decades of the elderly population at highest risk for Parkinson disease (PD) makes identification of factors that promote or prevent the disease an important goal...
  21. ncbi request reprint Association of body mass index with blood pressure in elderly Japanese American men. The Honolulu Heart Program
    K H Masaki
    Honolulu Heart Program, Kuakini Medical Center, HI 96817, USA
    Hypertension 29:673-7. 1997
    ..These results show that obesity and high blood pressure continue to be highly correlated even in old age and suggest that it may be possible to modify rates of hypertension by changes in body weight...
  22. ncbi request reprint Relationship between plasma glucose concentrations and Native Hawaiian Ancestry: The Native Hawaiian Health Research Project
    A Grandinetti
    Pacific Biomedical Research Center, University of Hawaii at Manoa, Honolulu, Hawaii, USA
    Int J Obes Relat Metab Disord 26:778-82. 2002
    ..To investigate the relationship between fasting glucose and 2 h glucose with percentage of Hawaiian ancestry and ethnic admixture...
  23. ncbi request reprint Accuracy of clinical criteria for AD in the Honolulu-Asia Aging Study, a population-based study
    H Petrovitch
    Pacific Health Research Institute, Honolulu, HI 96813, USA
    Neurology 57:226-34. 2001
    ..AD is neuropathologically confirmed for more than 80% of cases at major referral centers (primarily Caucasians); however, information on diagnostic accuracy in population-based studies and studies of different ethnic groups is limited...
  24. ncbi request reprint Postural hypertension in elderly men--the Honolulu Heart Program
    K Alagiakrishnan
    John A Burns School of Medicine, University of Hawaii, Honolulu 96817, USA
    Hawaii Med J 59:48-50. 2000
    ..Although there was a high prevalence of postural hypertension in this cohort, its clinical significance is questionable as there were no significant correlations with morbidity and subsequent mortality...
  25. doi request reprint Differences in lipoprotein particle subclass distribution for Japanese Americans in Hawaii and Japanese in Japan: the INTERLIPID study
    J David Curb
    Department of Geriatric Medicine, John A Burns School of Medicine, University of Hawaii, 347 N Kuakini St HPM9, Honolulu, HI 96817, USA
    J Clin Lipidol 5:30-6. 2011
    ..Rates of CHD appear to continue to be lower in Japan despite increasing cholesterol levels in Japan and decreasing CHD rates in the United States...
  26. ncbi request reprint Mediators of lifestyle behavior change in Native Hawaiians: initial findings from the Native Hawaiian Diabetes Intervention Program
    M K Mau
    Department of Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96813, USA
    Diabetes Care 24:1770-5. 2001
    ..To examine the association of stage of change with diet and exercise behaviors in response to a lifestyle intervention for Native Hawaiians (NHs)...
  27. ncbi request reprint A prospective study of HDL-C and cholesteryl ester transfer protein gene mutations and the risk of coronary heart disease in the elderly
    J D Curb
    Pacific Health Research Institute, Honolulu, HI, USA
    J Lipid Res 45:948-53. 2004
    ..These data indicate that HDL-C remains an important risk factor for CHD in the elderly. Whether a CETP mutation offers additional protection against CHD warrants further investigation...
  28. ncbi request reprint Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group
    J B Kostis
    Department of Medicine, Center for Disease Management and Clinical Outcomes, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903 0019, USA
    JAMA 278:212-6. 1997
    ..Heart failure is often preceded by isolated systolic hypertension, but the effectiveness of antihypertensive treatment in preventing heart failure is not known...
  29. ncbi request reprint Proteinuria and risk for stroke and coronary heart disease during 27 years of follow-up: the Honolulu Heart Program
    James R Madison
    Department of Internal Medicine, University of Hawaii, John A Burns School of Medicine, Honolulu, USA
    Arch Intern Med 166:884-9. 2006
    ..Urinary protein excretion has been linked to coronary heart disease (CHD); the relationship to stroke is less clear. We assessed whether urine dipstick screening for protein predicted stroke and CHD in the Honolulu Heart Program cohort...
  30. ncbi request reprint Disability and depression: investigating a complex relation using physical performance measures
    Masahiko Yanagita
    Fukui Prefectural University, Fukui, Japan
    Am J Geriatr Psychiatry 14:1060-8. 2006
    ..The objective of this study was to examine the relation of physical performance measures with depressive symptoms in older men...
  31. ncbi request reprint Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 162:404-14. 2005
    ..These analyses have implications for both the design and the analysis of observational studies...
  32. ncbi request reprint Are remnant-like particles independent predictors of coronary heart disease incidence? The Honolulu Heart study
    Claudia Imke
    Department of Public Health Sciences and Epidemiology, John A Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii, USA
    Arterioscler Thromb Vasc Biol 25:1718-22. 2005
    ..This is the first long-term prospective investigation of the relationship between remnant-like particles and a cardiovascular disease outcome in healthy men...
  33. ncbi request reprint C-reactive protein, cardiovascular disease and stroke: new roles for an old biomarker
    Bradley J Willcox
    Pacific Health Research Institute, 846 South Hotel St, Suite 301, Honolulu, HI 96813, USA
    Expert Rev Neurother 4:507-18. 2004
    ..New and increasingly available high-sensitivity assays may make C-reactive protein a standard screening tool for cardiovascular disease...
  34. ncbi request reprint Relation of long chain n-3 polyunsaturated fatty acid intake to serum high density lipoprotein cholesterol among Japanese men in Japan and Japanese-American men in Hawaii: the INTERLIPID study
    Nagako Okuda
    Department of Health Science, Shiga University of Medical Science, Tsukinowa cho, Seta, Otsu, Shiga 520 2192, Japan
    Atherosclerosis 178:371-9. 2005
    ..011). This association was not observed in women. This positive association of dietary n-3 PUFA with serum HDL cholesterol may partially explain the low mortality from CHD among Japanese men...
  35. doi request reprint Low-fat dietary pattern and risk of treated diabetes mellitus in postmenopausal women: the Women's Health Initiative randomized controlled dietary modification trial
    Lesley F Tinker
    Women s Health Initiative, Fred Hutchinson Cancer Research Center, PO Box 19024, Mail Stop M3 A410, Seattle, WA 98109, USA
    Arch Intern Med 168:1500-11. 2008
    ..This study was undertaken to assess the effects of a low-fat dietary pattern on incidence of treated diabetes among generally healthy postmenopausal women...
  36. ncbi request reprint Dietary factors related to higher plasma fibrinogen levels of Japanese-americans in hawaii compared with Japanese in Japan
    Katsuyuki Miura
    Department of Epidemiology and Public Health, Kanazawa Medical University, 1 1 Daigaku, Uchinada, Ishikawa, 920 0293, Japan
    Arterioscler Thromb Vasc Biol 26:1674-9. 2006
    ..We investigated whether dietary factors explain higher plasma fibrinogen levels in Japanese emigrants living a Western lifestyle in Hawaii compared with Japanese in Japan...
  37. ncbi request reprint Directly measured insulin resistance and the assessment of clustered cardiovascular risks in hypertension
    Ming Wei Lin
    Faculty of Medicine, National Yang Ming University School of Medicine, Taipei, Taiwan
    Am J Hypertens 19:1118-24. 2006
    ....
  38. ncbi request reprint Relation of dietary and other lifestyle traits to difference in serum adiponectin concentration of Japanese in Japan and Hawaii: the INTERLIPID Study
    Yasuyuki Nakamura
    Cardiovascular Epidemiology, Kyoto Women s University, Kyoto, Japan
    Am J Clin Nutr 88:424-30. 2008
    ..In initial analyses, we found significant differences between serum adiponectin in Japanese living in Japan and Hawaii...
  39. ncbi request reprint Bowel movement frequency in late-life and incidental Lewy bodies
    Robert D Abbott
    Division of Biostatistics and Epidemiology, University of Virginia School of Medicine, Charlottesville, Virginia 22908 0717, and Veterans Affairs Pacific Islands Health Care System, Honolulu, HI, USA
    Mov Disord 22:1581-6. 2007
    ..Infrequent bowel movements are associated with ILB. Findings provide evidence that constipation can predate the extrapyramidal signs of PD. Constipation could be one of the earliest markers of the beginning of PD processes...
  40. pmc Calcium plus vitamin D supplementation and the risk of incident diabetes in the Women's Health Initiative
    Ian H De Boer
    Division of Nephrology, University of Washington, 1959 NE Pacific Street, Seattle, WA 98195, USA
    Diabetes Care 31:701-7. 2008
    ..We examined the effect of calcium plus vitamin D supplementation on the incidence of drug-treated diabetes in postmenopausal women...
  41. pmc Marine-derived n-3 fatty acids and atherosclerosis in Japanese, Japanese-American, and white men: a cross-sectional study
    Akira Sekikawa
    University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Am Coll Cardiol 52:417-24. 2008
    ..We sought to examine whether marine-derived n-3 fatty acids are associated with less atherosclerosis in Japanese versus white populations in the U.S...
  42. pmc Cystatin-C, renal function, and incidence of hip fracture in postmenopausal women
    Andrea Z LaCroix
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 1024, USA
    J Am Geriatr Soc 56:1434-41. 2008
    ..To evaluate the association between chronic kidney disease and incident hip fracture using serum cystatin-C as a biomarker of renal function calculated without reference to muscle mass...
  43. ncbi request reprint Prospective association between low and high total and low-density lipoprotein cholesterol and coronary heart disease in elderly men
    J David Curb
    Honolulu Heart Program, Kuakini Medical Center, Honolulu, Hawaii, USA
    J Am Geriatr Soc 52:1975-80. 2004
    ..To examine the relationship between total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and the incidence of coronary heart disease (CHD) in elderly men...
  44. ncbi request reprint Heritability of left ventricular mass in Japanese families living in Hawaii: the SAPPHIRe Study
    Themistocles L Assimes
    Stanford University Medical Center, Division of Cardiovascular Medicine, Stanford, California, USA
    J Hypertens 25:985-92. 2007
    ..An estimate of this proportion has not been reported previously in an East Asian population. The objective of this study was to estimate the heritability of LV mass in Japanese families living in Hawaii...
  45. ncbi request reprint Age-related changes in risk factor effects on the incidence of thromboembolic and hemorrhagic stroke
    Robert D Abbott
    Division of Biostatistics and Epidemiology, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    J Clin Epidemiol 56:479-86. 2003
    ..Control of diabetes and the encouragement of active lifestyles in the elderly seem to be especially important...
  46. ncbi request reprint Combined analysis of Women's Health Initiative observational and clinical trial data on postmenopausal hormone treatment and cardiovascular disease
    Ross L Prentice
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Am J Epidemiol 163:589-99. 2006
    ..An application to postmenopausal hormone treatment effects on coronary heart disease among younger women is also provided...
  47. ncbi request reprint The American Diabetes Association and World Health Organization classifications for diabetes: their impact on diabetes prevalence and total and cardiovascular disease mortality in elderly Japanese-American men
    Beatriz L Rodriguez
    Division of Clinical Epidemiology and the Department of Geriatric Medicine, John A Burns School of Medicine, University of Hawaii at Manoa, Hawaii
    Diabetes Care 25:951-5. 2002
    ....
  48. ncbi request reprint Dietary magnesium intake and the future risk of coronary heart disease (the Honolulu Heart Program)
    Robert D Abbott
    Division of Biostatistics and Epidemiology, Department of Health Evaluation Sciences, University of Virginia School of Medicine, PO Box 800717, Charlottesville, VA 22908 0717, USA
    Am J Cardiol 92:665-9. 2003
    ..We conclude that the intake of dietary Mg is associated with a reduced risk of CHD. Whether increases in dietary Mg intake can alter the future risk of disease warrants further study...
  49. ncbi request reprint C-reactive protein and myocardial infarction
    Pamela Sakkinen
    Laboratory for Clinical Biochemistry Research, University of Vermont, Burlington, VT, USA
    J Clin Epidemiol 55:445-51. 2002
    ....
  50. ncbi request reprint Age-related changes in risk factor effects on the incidence of coronary heart disease
    Robert D Abbott
    Division of Biostatistics and Epidemiology, University of Virginia School of Medicine, Charlottesville, VA, USA
    Ann Epidemiol 12:173-81. 2002
    ..The purpose of this report is to examine the potential for risk factor effects on the incidence of CHD to change over a broad range of ages from middle adulthood to late-life...
  51. ncbi request reprint High density lipoprotein cholesterol and the risk of stroke in elderly men: the Honolulu heart program
    J David Curb
    Pacific Health Research Institute, Honolulu, HI 96817, USA
    Am J Epidemiol 160:150-7. 2004
    ..These findings suggest that HDL cholesterol level is inversely related to the risk of thromboembolic stroke in elderly men. Whether HDL cholesterol alters the effect of other factors on stroke risk in elderly men warrants further study...
  52. ncbi request reprint Risk of hospitalized stroke in men enrolled in the Honolulu Heart Program and the Framingham Study: A comparison of incidence and risk factor effects
    Beatriz L Rodriguez
    Division of Clinical Epidemiology, John A Burns School of Medicine, University of Hawaii at Manoa, USA
    Stroke 33:230-6. 2002
    ..Our purpose was to compare the 20-year incidence of hospitalized stroke between Japanese-American men in the Honolulu Heart Program and white men in the Framingham Study...
  53. ncbi request reprint Risk factor clustering in the insulin resistance syndrome and its relationship to cardiovascular disease in postmenopausal white, black, hispanic, and Asian/Pacific Islander women
    Barbara V Howard
    MedStar Research Institute, Washington, DC, USA
    Metabolism 52:362-71. 2003
    ..0434) and strongly in black women (P =.0095). Components of the IR syndrome appear to be associated with CVD in postmenopausal women, although the magnitude of these relationships differed by ethnicity...
  54. pmc Difference in carotid intima-media thickness between Korean and Japanese men
    Jina Choo
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
    Ann Epidemiol 18:310-5. 2008
    ..We aimed to evaluate levels of carotid intima-media thickness (IMT) and coronary risk factors in Korean and Japanese men in the post-World War II birth cohort...
  55. ncbi request reprint Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study
    Reinhold Schmidt
    Department of Neurology, Karl Franzens University, Graz, Austria
    Ann Neurol 52:168-74. 2002
    ..These data support the view that inflammatory markers may reflect not only peripheral disease, but also cerebral disease mechanisms related to dementia, and that these processes are measurable long before clinical symptoms appear...
  56. doi request reprint A whole-genome scan for stroke or myocardial infarction in family blood pressure program families
    Richard Sherva
    Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, USA
    Stroke 39:1115-20. 2008
    ..Using data from the Family Blood Pressure Program, we tested for chromosomal regions linked to the composite phenotype of stroke or myocardial infarction in a large set of hypertensive families...
  57. ncbi request reprint Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span
    Bradley J Willcox
    Pacific Health Research Institute, 846 South Hotel Street, Suite 301, Honolulu, HI 96813, USA
    Ann N Y Acad Sci 1114:434-55. 2007
    ..This study lends epidemiologic support for phenotypic benefits of CR in humans and is consistent with the well-known literature on animals with regard to CR phenotypes and healthy aging...
  58. doi request reprint The negative correlation between plasma adiponectin and blood pressure depends on obesity: a family-based association study in SAPPHIRe
    Hung Yuan Li
    Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
    Am J Hypertens 21:471-6. 2008
    ..In order to minimize confounding effects from unidentified factors, a family-based design was employed to explore the relationship...
  59. ncbi request reprint How much should we eat? The association between energy intake and mortality in a 36-year follow-up study of Japanese-American men
    Bradley J Willcox
    Pacific Health Research Institute, 846 South Hotel St, Suite 301, Honolulu, HI 96813, USA
    J Gerontol A Biol Sci Med Sci 59:789-95. 2004
    ..Thus, we observed trends between low energy intake and reduced risk for all-cause mortality in humans until energy intake fell to less than half the group mean, consistent with previous findings in other species...
  60. doi request reprint Absence of evidence for an association between resistin gene variants and insulin resistance in an Asian population with low and high blood pressure
    Jennifer L Kimbell
    Pacific Health Research Institute, Honolulu, HI 96813, United States
    Diabetes Res Clin Pract 81:231-7. 2008
    ..We searched for associations between common resistin gene variants and factors related to insulin resistance in Asian individuals with high or low blood pressure (BP)...
  61. ncbi request reprint Overview: the Hawai'i Clinical and Translational Science Institute
    J David Curb
    John A Burns School of Medicine, University of Hawai i, USA
    Hawaii Med J 67:134-5. 2008
  62. doi request reprint Health-related quality of life of children and adolescents with type 1 or type 2 diabetes mellitus: SEARCH for Diabetes in Youth Study
    Michelle J Naughton
    Department of Social Sciences and Health Policy, Division of Public Health Sciences, Wake Forest University School of Medicine, 2000 W First St, Winston Salem, NC 27104, USA
    Arch Pediatr Adolesc Med 162:649-57. 2008
    ..To examine the associations between demographic and diabetes management variables and the health-related quality of life (HRQOL) of youths with type 1 or type 2 diabetes mellitus (DM)...
  63. ncbi request reprint Relationship of blood pressure with degree of Hawaiian ancestry
    Andrew Grandinetti
    Pacific Biomedical Research Center, University of Hawaii at Manoa, USA
    Ethn Dis 12:221-8. 2002
    ..These results suggest that percentage of Hawaiian ancestry may act as a marker for important cultural or genetic risk factors for hypertension...
  64. pmc Effect of calcium and vitamin D supplementation on blood pressure: the Women's Health Initiative Randomized Trial
    Karen L Margolis
    HealthPartners Research Foundation, Box 1524, Mailstop 21111R, Minneapolis, Minnesota 55440 1524, USA
    Hypertension 52:847-55. 2008
    ..01 (95% CI: 0.96 to 1.06.) In postmenopausal women, calcium plus vitamin D3 supplementation did not reduce either blood pressure or the risk of developing hypertension over 7 years of follow-up...
  65. doi request reprint Antioxidants in cardiovascular health and disease: key lessons from epidemiologic studies
    Bradley J Willcox
    Pacific Health Research Institute, 846 South Hotel Street, Honolulu, HI 96813, USA
    Am J Cardiol 101:75D-86D. 2008
    ..This should help clarify the true potential utility of antioxidants in CVD and may lead to a better understanding of the role of oxidative stress in atherosclerosis...
  66. ncbi request reprint Coronary artery calcification and total mortality in elderly men
    Robert D Abbott
    Division of Biostatistics and Epidemiology, School of Medicine, University of Virginia, Charlottesville, Virginia 22908, USA
    J Am Geriatr Soc 55:1948-54. 2007
    ..To examine the relationship between coronary artery calcification (CAC) and mortality in a sample of elderly men...
  67. pmc Coronary artery calcification in Japanese men in Japan and Hawaii
    Robert D Abbott
    Division of Biostatistics and Epidemiology, University of Virginia School of Medicine, Charlottesville, VA 22908 0717, USA
    Am J Epidemiol 166:1280-7. 2007
    ..0 (95% confidence interval: 2.2, 7.4). Further studies are needed to identify factors that protect against atherosclerosis in Japanese men in Japan...
  68. ncbi request reprint Human serum albumin levels and cardiovascular risk factors in elderly Japanese-American men: the Honolulu Heart Program
    Chung Eun Ha
    Department of Native Hawaiian Health, John A Burns School of Medicine, University of Hawai i, Honolulu 96813, USA
    Hawaii Med J 66:148, 150-2. 2007
    ..However, the model R-square for all variables was only 0.10. In conclusion, HSA levels are significantly associated with several traditional cardiovascular risk factors, particularly serum lipid levels...
  69. ncbi request reprint Diabetes care quality in the Veterans Affairs Health Care System and commercial managed care: the TRIAD study
    Eve A Kerr
    Veterans Affairs Ann Arbor Healthcare System, Center for Practice Management and Outcomes Research, and University of Michigan, Ann Arbor, Michigan 48113 0170, USA
    Ann Intern Med 141:272-81. 2004
    ..No studies have compared care in the Department of Veterans Affairs (VA) with that delivered in commercial managed care organizations, nor have studies focused in depth on care comparisons for chronic, outpatient conditions...
  70. ncbi request reprint Managed care organization and the quality of diabetes care: the Translating Research Into Action for Diabetes (TRIAD) study
    Catherine Kim
    Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
    Diabetes Care 27:1529-34. 2004
    ..To examine the association between the organizational model and diabetes processes of care...
  71. ncbi request reprint Depressive symptoms and heart rate variability in postmenopausal women
    Chin K Kim
    Division of Cardiovascular Medicine, University of Florida, Gainesville 32610 0277, USA
    Arch Intern Med 165:1239-44. 2005
    ..Findings regarding a relationship between depressive symptoms and heart rate variability that could explain increased cardiovascular risk have been inconsistent across studies...
  72. ncbi request reprint Referral management and the care of patients with diabetes: the Translating Research Into Action for Diabetes (TRIAD) study
    Catherine Kim
    Division of General Internal Medicine, Department of Medicine, University of Michigan, Ann Arbor, Mich, USA
    Am J Manag Care 10:137-43. 2004
    ..To examine the effect of referral management on diabetes care...
  73. ncbi request reprint Two major QTLs and several others relate to factors of metabolic syndrome in the family blood pressure program
    Aldi T Kraja
    Division of Biostatistics, Washington University School of Medicine, St Louis, MO 63123, USA
    Hypertension 46:751-7. 2005
    ..5, and 30 additional ones with lod score >1.7, offer hope for dissecting the genetic architecture of metabolic syndrome with beneficial implications for molecular diagnosis, prognosis, and in potential medical intervention...
  74. ncbi request reprint The prevalence and prognosis of a Brugada-type electrocardiogram in a population of middle-aged Japanese-American men with follow-up of three decades
    Hiroki Ito
    John A Burns School of Medicine, University of Hawaii, Honolulu, HI, USA
    Am J Med Sci 331:25-9. 2006
    ..There are conflicting data about its prevalence and prognosis. Particularly, population-based studies are lacking in the United States and other countries...
  75. ncbi request reprint Effect of estrogen plus progestin on stroke in postmenopausal women: the Women's Health Initiative: a randomized trial
    Sylvia Wassertheil-Smoller
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    JAMA 289:2673-84. 2003
    ..The Women's Health Initiative (WHI) trial of estrogen plus progestin was stopped early because of adverse effects, including an increased risk of stroke in the estrogen plus progestin group...
  76. ncbi request reprint Venous thrombosis and conjugated equine estrogen in women without a uterus
    J David Curb
    University of Hawaii and Pacific Health Research Institute, Honolulu, USA
    Arch Intern Med 166:772-80. 2006
    ..Clinical trial data on the effects of estrogen alone on VT are limited...
  77. ncbi request reprint Siblings of Okinawan centenarians share lifelong mortality advantages
    Bradley J Willcox
    Pacific Health Research Institute, Honolulu, Hawaii, USA
    J Gerontol A Biol Sci Med Sci 61:345-54. 2006
    ..58-fold likelihood, and male siblings a 5.43-fold likelihood, versus their birth cohorts, of reaching the age of 90 years. These data support a significant familial component to exceptional human longevity...
  78. ncbi request reprint Environmental, life-style, and physical precursors of clinical Parkinson's disease: recent findings from the Honolulu-Asia Aging Study
    Robert D Abbott
    University of Virginia Health System, Department of Health Evaluation Sciences, 800717, Charlottesville, Virginia 22908 0717, USA
    J Neurol 250:III30-9. 2003
    ..This report describes the relations between environmental, life-style, and physical attributes and the incidence of PD that have been observed in the Honolulu-Asia Aging Study...
  79. ncbi request reprint Performance-based measures of physical function for high-function populations
    J David Curb
    Pacific Health Research Institute, 846 South Hotel Street, Honolulu, HI 96813, USA
    J Am Geriatr Soc 54:737-42. 2006
    ..To improve and broaden the applicability of performance-based measures of function for use in clinical and research settings...
  80. ncbi request reprint Caloric restriction and human longevity: what can we learn from the Okinawans?
    D Craig Willcox
    College of Nursing, Okinawa Prefectural University, 1 24 1 Yogi, Naha, Okinawa 902 0076, Japan
    Biogerontology 7:173-7. 2006
    ..We review the human studies in the context of a special human population, older Okinawans, who appear to have undergone a mild form of prolonged CR for about half their adult lives...
  81. ncbi request reprint Favorable effects of non-instrumental resistance training on fat distribution and metabolic profiles in healthy elderly people
    Shigeki Tsuzuku
    Body Design Medical Institute Japan, 5 2 10 Shin Imazato Ikuno ku, Osaka, 544 0001, Japan
    Eur J Appl Physiol 99:549-55. 2007
    ..Relatively short-term, non-instrumental resistance training using body weight as a load was effective in improving fat distribution and metabolic profiles in healthy elderly people without weight loss...
  82. pmc Linkage and association analyses of type 2 diabetes/impaired glucose metabolism and adiponectin serum levels in Japanese Americans from Hawaii
    Ilija P Kovac
    Department of Psychiatry, McGill University, Alan Memorial Institute, R and T Building, 1033 Pine Avenue West, Montreal H3A 1A1, Quebec, Canada
    Diabetes 56:537-40. 2007
    ..2 cM. The present study was limited by relatively small sample size. Nevertheless, these results corroborate earlier studies, suggesting that further research is warranted in the candidate region approximately 30 cM on chromosome 14...
  83. ncbi request reprint [Electron-beam computed tomography for identification of high-risk persons in primary prevention of coronary heart disease in the United States and its implication for Japan]
    Akira Sekikawa
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
    Nihon Koshu Eisei Zasshi 50:183-93. 2003
    ..It is, therefore, important to evaluate subclinical atherosclerosis measured by EBCT in men in recent birth cohorts in Japan and compare it to that in men in the US in order to predict future trend in CHD in Japan...
  84. ncbi request reprint Comparison of self-report, hospital discharge codes, and adjudication of cardiovascular events in the Women's Health Initiative
    Susan R Heckbert
    Department of Epidemiology, Cardiovascular Health Research Unit, University of Washington, 1730 Minor Avenue, Seattle, WA 98101 1448, USA
    Am J Epidemiol 160:1152-8. 2004
    ....