David J Cuccia

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain
    David J Cuccia
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, California 92612, USA
    Opt Lett 30:1354-6. 2005
  2. ncbi Coregistration of diffuse optical spectroscopy and magnetic resonance imaging in a rat tumor model
    Sean Merritt
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
    Appl Opt 42:2951-9. 2003
  3. ncbi In vivo quantification of optical contrast agent dynamics in rat tumors by use of diffuse optical spectroscopy with magnetic resonance imaging coregistration
    David J Cuccia
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
    Appl Opt 42:2940-50. 2003
  4. ncbi Multispectral imaging of tissue absorption and scattering using spatial frequency domain imaging and a computed-tomography imaging spectrometer
    Jessie R Weber
    University of California, Irvine, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road East, Irvine, California, 92612, USA
    J Biomed Opt 16:011015. 2011
  5. ncbi Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 16:126013. 2011
  6. ncbi Quantitation and mapping of tissue optical properties using modulated imaging
    David J Cuccia
    Modulated Imaging, Inc, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 14:024012. 2009
  7. ncbi Method for depth-resolved quantitation of optical properties in layered media using spatially modulated quantitative spectroscopy
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 16:077002. 2011
  8. ncbi Postoperative quantitative assessment of reconstructive tissue status in a cutaneous flap model using spatial frequency domain imaging
    Amr Yafi
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, Calif 92617, USA
    Plast Reconstr Surg 127:117-30. 2011
  9. ncbi Effects of motion on optical properties in the spatial frequency domain
    John Quan Nguyen
    Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road, Irvine, California 92617 3010, USA
    J Biomed Opt 16:126009. 2011
  10. ncbi Diffuse optical imaging using spatially and temporally modulated light
    Thomas D O'Sullivan
    University of California, Irvine, Laser Microbeam and Medical Program LAMMP, Beckman Laser Institute and Medical Clinic, Irvine, California, USA
    J Biomed Opt 17:071311. 2012

Research Grants

  1. Pre-clinical Feasibility Study of Tissue Oxygenation Imager
    David Cuccia; Fiscal Year: 2006

Collaborators

Detail Information

Publications16

  1. ncbi Modulated imaging: quantitative analysis and tomography of turbid media in the spatial-frequency domain
    David J Cuccia
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, California 92612, USA
    Opt Lett 30:1354-6. 2005
    ..Experiments performed on turbid phantoms demonstrate that spatially modulated illumination facilitates quantitative wide-field optical property mapping and tomographic imaging in turbid media...
  2. ncbi Coregistration of diffuse optical spectroscopy and magnetic resonance imaging in a rat tumor model
    Sean Merritt
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
    Appl Opt 42:2951-9. 2003
    ..15 M/microM). Tissue hemoglobin oxygen saturation (StO2) also showed a large variation between tissue types: viable tissue had an optically measured StO2 value of 61 +/- 5%, whereas StO2 determined for necrotic tissue was 43 +/- 6%...
  3. ncbi In vivo quantification of optical contrast agent dynamics in rat tumors by use of diffuse optical spectroscopy with magnetic resonance imaging coregistration
    David J Cuccia
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
    Appl Opt 42:2940-50. 2003
    ..In contrast, MB behaves as a small-molecular-weight contrast agent that leaks rapidly from the vasculature into the extravascular, extracellular space, and is sensitive to blood flow and the arterial input function...
  4. ncbi Multispectral imaging of tissue absorption and scattering using spatial frequency domain imaging and a computed-tomography imaging spectrometer
    Jessie R Weber
    University of California, Irvine, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road East, Irvine, California, 92612, USA
    J Biomed Opt 16:011015. 2011
    ..The SFDI-CTIS platform was applied to a mouse model of brain injury in order to demonstrate the utility of this approach in characterizing spatially and spectrally varying tissue optical properties...
  5. ncbi Quantitative fluorescence imaging of protoporphyrin IX through determination of tissue optical properties in the spatial frequency domain
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 16:126013. 2011
    ..This method was subsequently applied to the determination of PpIX concentration from in vivo normal skin where the model-based correction determined a concentration of 1.6 μg/ml, which is in agreement with literature...
  6. ncbi Quantitation and mapping of tissue optical properties using modulated imaging
    David J Cuccia
    Modulated Imaging, Inc, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 14:024012. 2009
    ..Last, metrics of spatial resolution are assessed through both simulations and measurements of spatially heterogeneous phantoms...
  7. ncbi Method for depth-resolved quantitation of optical properties in layered media using spatially modulated quantitative spectroscopy
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, California 92612, USA
    J Biomed Opt 16:077002. 2011
    ....
  8. ncbi Postoperative quantitative assessment of reconstructive tissue status in a cutaneous flap model using spatial frequency domain imaging
    Amr Yafi
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, Calif 92617, USA
    Plast Reconstr Surg 127:117-30. 2011
    ..The purpose of this study was to investigate the capabilities of a novel optical wide-field imaging technology known as spatial frequency domain imaging to quantitatively assess reconstructive tissue status...
  9. ncbi Effects of motion on optical properties in the spatial frequency domain
    John Quan Nguyen
    Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Road, Irvine, California 92617 3010, USA
    J Biomed Opt 16:126009. 2011
    ....
  10. ncbi Diffuse optical imaging using spatially and temporally modulated light
    Thomas D O'Sullivan
    University of California, Irvine, Laser Microbeam and Medical Program LAMMP, Beckman Laser Institute and Medical Clinic, Irvine, California, USA
    J Biomed Opt 17:071311. 2012
    ....
  11. ncbi Quantitative determination of dynamical properties using coherent spatial frequency domain imaging
    Tyler B Rice
    Department of Physics, University of California, Irvine, Irvine, California 92697, USA
    J Opt Soc Am A Opt Image Sci Vis 28:2108-14. 2011
    ..7E-07 and 5.35 mm²/s, respectively. For scattering particles in water-glycerin solutions, the fit fractional changes in D(b) with changes in viscosity were all found to be within 3% of the expected value...
  12. ncbi Wavelength optimization for rapid chromophore mapping using spatial frequency domain imaging
    Amaan Mazhar
    University of California, Department of Biomedical Engineering, Irvine, CA 92612, USA
    J Biomed Opt 15:061716. 2010
    ..5s compared to 50s for a full 34-wavelength acquisition. The wavelength optimization enables dynamic imaging of arterial occlusions with improved spatial resolution due to reduction of motion artifacts...
  13. ncbi Determination of optical properties of turbid media spanning visible and near-infrared regimes via spatially modulated quantitative spectroscopy
    Rolf B Saager
    University of California Irvine, Beckman Laser Institute, Irvine, California 92612, USA mail
    J Biomed Opt 15:017012. 2010
    ..The resultant absorption spectrum was well described by a multichromophore fit, and the quantitative values for oxy- and deoxyhemoglobin, water, and melanin were within published ranges for skin...
  14. ncbi Wide-field spatial mapping of in vivo tattoo skin optical properties using modulated imaging
    Frederick R Ayers
    University of California Irvine, Beckman Laser Institute, Irvine, California 92612, USA
    Lasers Surg Med 41:442-53. 2009
    ..MI provides quantitative measurements of multi-colored tattooed skin which may help guide treatment and objectively assess response...
  15. ncbi Modulated imaging in layered media
    Jessie R Weber
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, CA 92692, USA
    Conf Proc IEEE Eng Med Biol Soc . 2006
    ..This technique is used to provide quantitative, depth-resolved functional physiologic information with applications in layered tissues including cortex, retina and skin...
  16. ncbi Congruent MRI and near-infrared spectroscopy for functional and structural imaging of tumors
    Gultekin Gulsen
    John Tu and Thomas Yuen Center for Functional Onco Imaging, University of California Irvine, Irvine, California 92697, USA
    Technol Cancer Res Treat 1:497-505. 2002
    ....

Research Grants2

  1. Pre-clinical Feasibility Study of Tissue Oxygenation Imager
    David Cuccia; Fiscal Year: 2006
    ..The results of this work will provide essential design for building a dedicated prototype imaging oximeter system for evaluating clinical wounds in Phase II. ..