Gyorgyi Csankovszki

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. pmc Finding a balance: how diverse dosage compensation strategies modify histone h4 to regulate transcription
    Michael B Wells
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, MI 48109 1048, USA
    Genet Res Int 2012:795069. 2012
  2. pmc Restricting dosage compensation complex binding to the X chromosomes by H2A.Z/HTZ-1
    Emily L Petty
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA
    PLoS Genet 5:e1000699. 2009
  3. pmc Regulation of DCC localization by HTZ-1/H2A.Z and DPY-30 does not correlate with H3K4 methylation levels
    Emily Petty
    Department of Molecular, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e25973. 2011
  4. pmc Three distinct condensin complexes control C. elegans chromosome dynamics
    Gyorgyi Csankovszki
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA
    Curr Biol 19:9-19. 2009
  5. ncbi request reprint Condensin function in dosage compensation
    Gyorgyi Csankovszki
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109 1048, USA
    Epigenetics 4:212-5. 2009
  6. pmc The worm solution: a chromosome-full of condensin helps gene expression go down
    Gyorgyi Csankovszki
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA
    Chromosome Res 17:621-35. 2009
  7. pmc Caenorhabditis elegans dosage compensation regulates histone H4 chromatin state on X chromosomes
    Michael B Wells
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA
    Mol Cell Biol 32:1710-9. 2012
  8. pmc Different roles for Aurora B in condensin targeting during mitosis and meiosis
    Karishma S Collette
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109 1048, USA
    J Cell Sci 124:3684-94. 2011
  9. pmc Condensin and the spindle midzone prevent cytokinesis failure induced by chromatin bridges in C. elegans embryos
    JOSHUA N BEMBENEK
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA
    Curr Biol 23:937-46. 2013
  10. pmc The onset of C. elegans dosage compensation is linked to the loss of developmental plasticity
    Laura M Custer
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, 830 N University Ave, Ann Arbor, MI 48109 1048, USA
    Dev Biol 385:279-90. 2014

Research Grants

  1. The Dosage Compensation Machinery of C. elegans
    Gyorgyi Csankovszki; Fiscal Year: 2007
  2. The Dosage Compensation Machinery of C. elegans
    Gyorgyi Csankovszki; Fiscal Year: 2010

Collaborators

Detail Information

Publications12

  1. pmc Finding a balance: how diverse dosage compensation strategies modify histone h4 to regulate transcription
    Michael B Wells
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, MI 48109 1048, USA
    Genet Res Int 2012:795069. 2012
    ....
  2. pmc Restricting dosage compensation complex binding to the X chromosomes by H2A.Z/HTZ-1
    Emily L Petty
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA
    PLoS Genet 5:e1000699. 2009
    ..We propose a model in which HTZ-1, directly or indirectly, serves to restrict the dosage compensation complex to the X chromosome by acting as or regulating the activity of an autosomal repellant...
  3. pmc Regulation of DCC localization by HTZ-1/H2A.Z and DPY-30 does not correlate with H3K4 methylation levels
    Emily Petty
    Department of Molecular, University of Michigan, Ann Arbor, Michigan, United States of America
    PLoS ONE 6:e25973. 2011
    ..Additionally, loss of H3K4 methylation does not enhance DCC mislocalization in htz-1 animals. We conclude that DPY-30 and HTZ-1 have unique functions in DCC localization, both of which are largely independent of H3K4 methylation...
  4. pmc Three distinct condensin complexes control C. elegans chromosome dynamics
    Gyorgyi Csankovszki
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA
    Curr Biol 19:9-19. 2009
    ..Instead, its condensin I-like complex (here called condensin I(DC)) dampens gene expression along hermaphrodite X chromosomes during dosage compensation...
  5. ncbi request reprint Condensin function in dosage compensation
    Gyorgyi Csankovszki
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109 1048, USA
    Epigenetics 4:212-5. 2009
    ..We discuss how during worm dosage compensation a condensin-mediated function may guide the organization of the interphase chromatin fibers, leading to the formation of a repressive nuclear compartment...
  6. pmc The worm solution: a chromosome-full of condensin helps gene expression go down
    Gyorgyi Csankovszki
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA
    Chromosome Res 17:621-35. 2009
    ..Worm dosage compensation represents an excellent model system to study how condensin-mediated changes in higher order chromatin organization affect gene expression...
  7. pmc Caenorhabditis elegans dosage compensation regulates histone H4 chromatin state on X chromosomes
    Michael B Wells
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA
    Mol Cell Biol 32:1710-9. 2012
    ....
  8. pmc Different roles for Aurora B in condensin targeting during mitosis and meiosis
    Karishma S Collette
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109 1048, USA
    J Cell Sci 124:3684-94. 2011
    ..By contrast, during meiosis, AIR-2 is not required for condensin I chromosomal association, but it provides cues for correct spatial targeting of the complex...
  9. pmc Condensin and the spindle midzone prevent cytokinesis failure induced by chromatin bridges in C. elegans embryos
    JOSHUA N BEMBENEK
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA
    Curr Biol 23:937-46. 2013
    ..Two unanswered questions in the proposed mechanistic pathway of the abscission checkpoint concern factors involved in (1) resolving the obstructions and (2) coordinating obstruction resolution with the delay in cytokinesis...
  10. pmc The onset of C. elegans dosage compensation is linked to the loss of developmental plasticity
    Laura M Custer
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, 830 N University Ave, Ann Arbor, MI 48109 1048, USA
    Dev Biol 385:279-90. 2014
    ..We propose that as embryonic blastomeres lose their developmental plasticity, hermaphrodite X chromosomes transition from a MES protein-regulated state to DCC-mediated repression. ..
  11. pmc Two classes of dosage compensation complex binding elements along Caenorhabditis elegans X chromosomes
    Timothy A Blauwkamp
    Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109 1048, USA
    Mol Cell Biol 29:2023-31. 2009
    ..These results suggest that two distinct classes of DCC-binding elements facilitate recruitment and spreading of the DCC along the X chromosome...
  12. pmc Unexpected role for dosage compensation in the control of dauer arrest, insulin-like signaling, and FoxO transcription factor activity in Caenorhabditis elegans
    Kathleen J Dumas
    Life Sciences Institute, University of Michigan, Ann Arbor, Michigan 48109, USA
    Genetics 194:619-29. 2013
    ....

Research Grants4

  1. The Dosage Compensation Machinery of C. elegans
    Gyorgyi Csankovszki; Fiscal Year: 2007
    ....
  2. The Dosage Compensation Machinery of C. elegans
    Gyorgyi Csankovszki; Fiscal Year: 2010
    ....