Research Topics
Genomes and GenesSpecies | Julius M CruseSummaryAffiliation: University of Mississippi Medical Center Country: USA Publications
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Detail Information
Publications
Quantitative analysis of adhesion molecules on cellular constituents of the human uterine microenvironment under the influence of estrogen and progesteroneMartha N Brackin
Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216, USA
Exp Mol Pathol 72:91-114. 2002..It is likely that many adhesion molecules play a role in the recruitment and retainment of specialized lymphocytes within the uterine microenvironment. (Mackay et al., 1990)...
Aberrant expression of CD7, CD56, and CD79a antigens in acute myeloid leukemiasJulius M Cruse
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 79:39-41. 2005..The aberrant expression of CD7, CD56, and CD79a, representing the capacity of these leukemias for trilineal expression of leukocyte differentiation antigens, portends a poor prognosis...
Diminished CD10, CD13, and CD15 expression in a differentiated granulocyte population in CMLJulius M Cruse
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 83:274-6. 2007..e., 13 (81.3%) cases demonstrated normal expression. Therefore, these results point to frequently decreased expression levels of CD10, CD13, and CD15 and rarely decreased expression levels of CD33 in association with CML...
Differential cytokine and Toll-like receptor expression in leukemiaRachel N Webb
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 83:464-70. 2007..These results warrant further study of the mechanism and potential therapeutic value targeting these leukemic patterns...
History of medicine: the metamorphosis of scientific medicine in the ever-present pastJ M Cruse
Department of Pathology, The University of Mississippi Medical Center, Jackson 39216 4505, USA
Am J Med Sci 318:171-80. 1999..Advances in medical knowledge have resulted not only from developments in technology but from increased access to current information provided through libraries such as the National Library of Medicine in Bethesda, Maryland...
Cellular and molecular alterations in spinal cord injury patients with pressure ulcers: a preliminary reportJ M Cruse
Department of Pathology, School of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi 39216 4505, USA
Exp Mol Pathol 72:124-31. 2002..These findings showed that delayed healing of pressure ulcers in SCI patients can be attributed to reduced adhesion molecule expression, impaired cell-cell interaction, and lack of extracellular matrix structural and functional protein...
Antigenic transformation in plasma cell dyscrasiaJulius M Cruse
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 81:157-61. 2006..5%). Our results point to the value of quantitative fluorescence intensity in the flow cytometric evaluation of CD molecular expression or deletion in the diagnosis of hematopathologic disorders, such as plasma cell dyscrasia...
Effects of tumor-enhancing IgG2 on macrophage functionJulius M Cruse
Department of Pathology, School of Medicine, University of Mississippi Medical Center, Jackson, MI 39216, USA
Exp Mol Pathol 77:43-8. 2004..In contrast to protection, te IgG(2) alloantibody facilitates macrophage-mediated allograft destruction...
Function of CD80 and CD86 on monocyte- and stem cell-derived dendritic cellsSmaroula Dilioglou
Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216 4505, USA
Exp Mol Pathol 75:217-27. 2003..These studies demonstrate that DC association with distinct hematopoietic lineages is of relevance in transplantation and vaccine therapies...
The immunophenotype of pre-TALL/LBL revisitedRobert E Lewis
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, Mississippi 39216, USA
Exp Mol Pathol 81:162-5. 2006..3%) expressed CD13, while 2 (12.5%) cases expressed CD33 and CD117. Thus, these data point to the need for a more extensive study to reevaluate the current WHO defined immunophenotype used in the diagnosis of pre-TALL/LBL...
Dendritic cell differentiation and proliferation: enhancement by tumor necrosis factor-alphaRobert S Morrison
Department of Pathology, School of Medicine, University of Mississippi Medical Center, 2500 North State Street, Jackson, MI 39216, USA
Exp Mol Pathol 75:228-37. 2003..These studies support the prevalence of large numbers of DCs under inflammatory conditions, such as the rheumatoid joint, where local concentrations of TNFalpha are high...
Decreased humoral antibody episodes of acute renal allograft rejection in recipients expressing the HLA-DQβ1*0202 alleleVenkat K R Mannam
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 93:190-2. 2012..DQβ1*0202 allele expression in recipients could possibly be protective against acute humoral allograft rejection and might serve as a future criterion in recipient selection and in appropriate therapy for acute renal rejection episodes...
Surface and cytoplasmic immunoglobulin expression in B-cell chronic lymphocytic leukemia (CLL)Robert E Lewis
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 79:146-50. 2005..Also, of the 23 cases tested for CD22 expression, 16 (69.6%) were positive. These data question the use of both "weak" surface Ig expression and lack of CD22 expression as valid scoring criteria for CLL...
Contrasting antigenic maturation patterns in M0-M2 versus M3 acute myeloid leukemiasRobert E Lewis
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 83:269-73. 2007..In contrast to expression of the early markers CD34 and HLA-DR in the M0-M2 group, these were negative in the M3 cases which were characterized by heterogeneous CD13 and generally homogeneous and bright CD33 expression...
Zap-70 and CD38 as predictors of IgVH mutation in CLLJulius M Cruse
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 83:459-61. 2007..These data point to the need for a more extensive study to evaluate the significance of Zap-70 and CD38 expression as indicators of IgVH mutation status and prognosis of CLL patients...
Aberrant expression of T-cell markers in acute myeloid leukemiaRobert E Lewis
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 83:462-3. 2007..These results point to the need for a more extensive study to evaluate the potential prognostic significance of aberrant T-cell marker expression in AML...
Costimulatory function of umbilical cord blood CD14+ and CD34+ derived dendritic cellsSmaroula Dilioglou
Department of Pathology, University of Mississippi Medical Center, Jackson, MS 39216-4505, USA
Exp Mol Pathol 75:18-33. 2003..These studies demonstrate that DC association with distinct hematopoietic lineages is of relevance in transplantation and vaccine therapies...
Immunological enhancement revisitedJulius M Cruse
Department of Pathology, University of Mississippi School of Medicine, Jackson, Mississippi 39216, USA
Exp Mol Pathol 73:112-27. 2002
Aberrant myeloid marker expression in precursor B-cell and T-cell leukemiasJeanann L Suggs
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 83:471-3. 2007..Future studies will be directed to correlation of these markers with prognosis and therapeutic response, as well as whether drug therapies targeting myeloid antigens could be of use in treatment...
Toll-like receptors, cytokines and HIV-1Catherine M Sanders
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 84:31-6. 2008..These data point to the need for a more in-depth study to determine whether or not the up-regulation of Toll-like receptor expression increases cytokine expression via the NFkappaB pathway...
HLA DRB1*1503 allelic haplotype predominance and associated immunodysregulation in systemic lupus erythematosusM Jeanann L Suggs
Department of Immunopathology, University of Mississippi Medical Center, 2500 North State St, Jackson, MS 39216, USA
Exp Mol Pathol 91:548-62. 2011....
DRβ1*1501, DQβ1*0602 donor allelic haplotype and humoral antibody episodes of acute renal allograft rejectionMorgan Cowan
Department of Pathology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USA
Exp Mol Pathol 89:135-9. 2010..Future analysis of additional donor and recipient haplotypes will establish whether or not this is a useful predictor of humoral rejection episodes...
Toll-like receptor and chemokine receptor expression in HIV-infected T lymphocyte subsetsCatherine Miller Sanders
University of Mississippi Medical Center, 2500 N State St, Jackson, MS 39216, USA
Exp Mol Pathol 88:26-31. 2010..Results also reveal a positive correlation between CXCR4, CCR5, and TLR4 expression indicating that TLR4 expression and chemokine expression pathways are linked...
The fate of renal allografts hinges on responses of the microvascular endotheliumVenkat K R Mannam
Department of Pathology, University of Mississippi Medical Center, Jackson, MS, USA
Exp Mol Pathol 94:398-411. 2013....
Depletion of pro-inflammatory CD161(+) double negative (CD3(+)CD4(-)CD8(-)) T cells in AIDS patients is ameliorated by expansion of the γδ T cell populationWill L Singleterry
University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, United States
Exp Mol Pathol 92:155-9. 2012....
Serial monitoring of humoral antibody-mediated rejection of cardiac allografts by C4d staining of interstitial capillariesJeanann Suggs
Department of Pathology, University of Mississippi Medical Center, USA
Exp Mol Pathol 86:41-5. 2009....
