Research Topics
| A N CrowsonSummaryAffiliation: University of Oklahoma Country: USA Publications
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Detail Information
Publications
Cutaneous vasculitis: a reviewA Neil Crowson
Dermatology and Pathology, University of Oklahoma, Tulsa, OK, USA
J Cutan Pathol 30:161-73. 2003....- Progress in the understanding of the pathology and pathogenesis of cutaneous drug eruptions : implications for managementA Neil Crowson
University of Oklahoma and Regional Medical Laboratories, Tulsa, Oklahoma, USA
Am J Clin Dermatol 4:407-28. 2003..Oral or topical corticosteroids can be administered to aid in the resolution of some types of eruptions. Antihistamines or anti-inflammatory agents may also be administered for some eruptions... - Basal cell carcinoma: biology, morphology and clinical implicationsA Neil Crowson
Department of Dermatology, Pathology and Surgery, University of Oklahoma, Tulsa, OK 74114 4109, USA
Mod Pathol 19:S127-47. 2006..The purpose of this review article is to summate the research advances in our understanding of BCC biology and to acquaint pathologists and clinicians to the practical issues in BCC diagnosis and subclassification which flow there from... - Prognosticators of melanoma, the melanoma report, and the sentinel lymph nodeA Neil Crowson
Department of Dermatology, University of Oklahoma and Regional Medical Laboratories, St John Medical Center, Tulsa, OK 74104, USA
Mod Pathol 19:S71-87. 2006..The purpose of this review is to bring to the attention of anatomic pathologists the essential characteristics of the pathology report for primary cutaneous melanoma in the modern era... - Pyoderma gangrenosum: a reviewA Neil Crowson
Department of Dermatology, University of Oklahoma, Tulsa, OK, USA
J Cutan Pathol 30:97-107. 2003..In this review, we describe in detail the different clinicopathologic forms of PG, summarize the diseases associated with this process in the literature and in our experience, and briefly review the treatment options... - Malignant adnexal neoplasmsA Neil Crowson
Department of Dermatology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, OK 74114 4109, USA
Mod Pathol 19:S93-S126. 2006..The purpose of this review is to discuss in detail the malignant neoplasms of the cutaneous adnexae and their benign and prognostically indeterminate mimics... - Unusual histologic and clinical variants of melanoma: implications for therapyA Neil Crowson
Regional Medical Laboratories, St John Medical Center, 1923 South Utica Avenue, Tulsa, OK 74104, USA
Curr Treat Options Oncol 7:169-80. 2006..Because identification of some of these melanoma subtypes has specific implications for the therapeutic approach and some may mimic other forms of epithelial or mesenchymal neoplasia, their recognition is key to patient management... - Unusual histologic and clinical variants of melanoma: implications for therapyA Neil Crowson
Regional Medical Laboratories, St John Medical Center, 1923 S Utica Avenue, Tulsa, OK 74104, USA
Curr Oncol Rep 9:403-10. 2007..As identification of some of these melanoma subtypes has specific implications for the therapeutic approach, and as some may mimic other forms of epithelial or mesenchymal neoplasia, their recognition is key to patient management... - Clear cell atypical fibroxanthoma:a clinicopathologic studyA Neil Crowson
Department of Dermatology, University of Oklahoma, USA Regional Medical Laboratory, St John Medical Center, 1923 S Utica Street, Tulsa, OK 74114 4109, USA
J Cutan Pathol 29:374-81. 2002..Among the rarest variants is the clear cell AFX, a lesion which raises consideration to a differential diagnosis encompassing a variety of neoplastic and non-neoplastic clear cell proliferations... - The molecular basis of melanomagenesis and the metastatic phenotypeA Neil Crowson
Department of Dermatology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, OK 74114 4109, USA
Semin Oncol 34:476-90. 2007..These events have specific morphologic correlates that will be briefly addressed. Where relevant, we will address certain of the modern pharmacogenetic strategies that flow from these novel observations concerning melanoma biology... 
Interface dermatitisA Neil Crowson
Department of Dermatology, University of Oklahoma and Regional Medical Laboratories, St John Medical Center, 1923 S Utica Ave, Tulsa, OK 74104, USA
Arch Pathol Lab Med 132:652-66. 2008..In the case of lymphocytic interface dermatitis, the latter is often termed a lichenoid interface dermatitis. This review focuses upon the mononuclear cell-predominant forms of interface dermatitis...- The cutaneous pathology of lupus erythematosus: a reviewA N Crowson
Central Medical Laboratories, Winnipeg, MB, Canada
J Cutan Pathol 28:1-23. 2001.... - Idiopathic perniosis and its mimics: a clinical and histological study of 38 casesA N Crowson
Department of Laboratories, Misericordia General Hospital, Winnipeg, Manitoba, Canada
Hum Pathol 28:478-84. 1997.... - Imiquimod as an antiaging agentSara Metcalf
Department of Dermatology, University of Oklahoma, Oklahoma City, Oklahoma, USA
J Am Acad Dermatol 56:422-5. 2007..There is, however, limited evidence demonstrating the use of topical imiquimod application as an antiaging treatment... - Towards non-invasive screening of skin lesions by near-infrared spectroscopyL M McIntosh
Institute for Biodiagnostics, National Research Council of Canada, Winnipeg, MB, Canada
J Invest Dermatol 116:175-81. 2001..Linear discriminant analysis classified spectra from benign lesions compared with premalignant or malignant lesions with high accuracy. Near-infrared spectroscopy is a promising noninvasive technique for the screening of skin lesions... - Pathologic quiz case: an indurated plaque on the ankle of a 74-year-old woman. Interstitial granulomatous drug reactionKoushan Siami
Department of Pathology, University of Oklahoma, Health Sciences Center, Oklahoma City, Okla 73104, USA
Arch Pathol Lab Med 128:e129-30. 2004 - Atypical lymphocytic lobular panniculitisCynthia M Magro
Department of Pathology, St John Medical Center and Regional Medical Laboratories, Tulsa, OK, USA
J Cutan Pathol 31:300-6. 2004..Although subcutaneous T-cell lymphoma (SCTCL) is considered an aggressive form of lymphoma, some patients manifest a long waxing and waning phase unaccompanied by constitutional symptoms... - Pathologic quiz case: pigmented lesion on the mons pubis of a 17-year-old girl. Compound nevus with features of milk mine nevusJane H Zhou
Department of Pathology, University of Oklahoma, Oklahoma City, OK 73104, USA
Arch Pathol Lab Med 127:e391-2. 2003 - Pathologic quiz case: brown macule on the thigh of a 71-year-old womanApple Newman
Department of Pathology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, Okla 74104, USA
Arch Pathol Lab Med 127:757-8. 2003 - Granulomatous eccrinotropic lymphomatoid papulosisA Neil Crowson
Central Medical Laboratories, Winnipeg, Canada
Am J Clin Pathol 119:731-9. 2003..Our findings suggest that pruritus, a younger age at diagnosis, and a more indolent course are defining clinical features... - Immunoglobulin A-associated lymphocytic vasculopathy: a clinicopathologic study of eight patientsA Neil Crowson
Central Medical Laboratories, Winnipeg, Manitoba, Canada
J Cutan Pathol 29:596-601. 2002..Thus, circulating ICs are a potential pathogenic basis of this eruption, the histologic differential diagnosis of which is idiopathic PP and PP of drug or viral etiology... - Medicolegal aspects of neoplastic dermatologyA Neil Crowson
Department of Dermatology, University of Oklahoma and Regional Medical Laboratory, St John Medical Center, Tulsa, OK 74114-4109, USA
Mod Pathol 19:S148-54. 2006..In this review, attention is paid to the source of medical malpractice claims and an abbreviated approach to specific strategies for risk management is presented... - Basosquamous carcinomaCarlos Garcia
Department of Dermatology at the Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma, USA
J Am Acad Dermatol 60:137-43. 2009..This concept has been perpetuated in the literature in spite of confusing terminology, limited scientific data, and the contradictory surgical experiences of some observers... - Pathologic quiz case: cystic tumor of the left eyebrow in a 42-year-old woman. Benign cutaneous adnexal tumor with combined folliculosebaceous and eccrine differentiationO Hans Iwenofu
Department of Pathology, University of Oklahoma, Health Science Center, Oklahoma City, OK 73104, USA
Arch Pathol Lab Med 128:1181-2. 2004 - The dermatopathologic manifestations of hepatitis C infection: a clinical, histological, and molecular assessment of 35 casesA Neil Crowson
Centeral Medical Laboratories, Winnipeg, Manitoba, Canada
Hum Pathol 34:573-9. 2003..Tropism of the virus to B lymphocytes provides a mechanism for the development of low-grade clonal B cell lymphoproliferative disease in this setting... - CD8+ lymphomatoid papulosis and its differential diagnosisCynthia M Magro
Department of Pathology, Ohio State University, Columbus 43210, USA
Am J Clin Pathol 125:490-501. 2006..CD30 expression can occur in other forms of CD8 lymphoproliferative disease unrelated to primary cutaneous anaplastic large cell lymphoma or LyP... - Drug-induced reversible lymphoid dyscrasia: a clonal lymphomatoid dermatitis of memory and activated T cellsCynthia M Magro
Department of Pathology, Division of Dermatopathology, Ohio State University, Columbus, USA
Hum Pathol 34:119-29. 2003..We propose the term "drug-induced reversible lymphoid dyscrasia" to describe this entity... - The precursors of malignant melanomaA Neil Crowson
Recent Results Cancer Res 160:75-84. 2002..The congenital nevus is briefly reviewed and emphasis is placed upon clues to malignant degeneration. The concept of lentigo maligna as a precursor as distinct from an in situ phase is detailed... - Melanocytic proliferations associated with lichen sclerosusJ Andrew Carlson
Division of Dermatology, Albany Medical College, Campus Box MC 81, Albany, NY 12208, USA
Arch Dermatol 138:77-87. 2002..To describe the clinicopathologic features of melanocytic proliferations associated with lichen sclerosus (LS) and to compare these findings with those in controls... - Unusual variants of malignant melanomaCynthia M Magro
Division of Dermatopathology, Department of Pathology, Ohio State University, Columbus, OH 43215, USA
Mod Pathol 19:S41-70. 2006..In this review, we will discuss in some detail certain of these novel clinicopathologic types of melanoma, as well as the abnormal phenotypic expressions seen in vertical growth phase melanoma... - Interstitial granulomatous dermatitis with arthritisA Neil Crowson
Hum Pathol 35:779-80. 2004 - Cutaneous immunocytoma: a clinical, histologic, and phenotypic study of 11 casesCynthia M Magro
Department of Pathology, The Ohio State University, Columbus, Ohio 43210, USA
Appl Immunohistochem Mol Morphol 12:216-24. 2004..Primary cutaneous immunocytoma appears to arise from a pre-existing state of reactive lymphoid hyperplasia. latrogenic and endogenous immune dysregulation including in the context of lymphotropic viral infections is implicated... - Assessment of T-cell clonality via T-cell receptor-gamma rearrangements in cutaneous T-cell-dominant infiltrates using polymerase chain reaction and single-stranded DNA conformational polymorphism assayMichael Chen
College of Medicine and Public Health, Ohio State University, Columbus, Ohio, USA
Appl Immunohistochem Mol Morphol 12:373-9. 2004..Although LCM appears to improve the sensitivity for detecting preneoplastic conditions, the relative specificity appears to be the same as that encountered with routine SSCP... - So called 'de novo intraepidermal epithelioid melanocytic dysplasia' is melanoma in situCynthia M Magro
Weill Medical College of Cornell University, New York, NY, USA
J Cutan Pathol 34:812. 2007 - Malignant proliferating pilar tumors arising in KID syndrome: a report of two patientsGurston G Nyquist
Department of Otolaryngology, Head and Neck Surgery, Kaiser Permanente, Oakland, CA, USA
Am J Med Genet A 143:734-41. 2007..Based on our findings, we believe that cancer surveillance in patients with KID syndrome should include screening for pilar tumors and their early removal to avoid development of malignant proliferating pilar tumors with poor prognosis... - Pityriasis lichenoides chronica: stratification by molecular and phenotypic profileCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University New York Presbyterian Hospital Cornell Campus, New York, NY 10021, USA
Hum Pathol 38:479-90. 2007..The limited propensity for progression to MF may reflect internal countercheck mechanisms of controlling clonally restricted CD4+ T-cell proliferations via CD8 and CD4/CD25+ regulatory T cells... - Pityriasis lichenoides: a clonal T-cell lymphoproliferative disorderCynthia Magro
Department of Pathology Ohio State University Medical Center, Columbus, OH 43210, USA
Hum Pathol 33:788-95. 2002.... - Parvoviral infection of endothelial cells and its possible role in vasculitis and autoimmune diseasesCynthia M Magro
Department of Pathology, Ohio State University, Columbus 43210, USA
J Rheumatol 29:1227-35. 2002..To analyze a series of biopsies from 16 patients who, on the basis of clinical and dermatopathologic findings, had a spectrum of connective tissue diseases (CTD), autoinflammatory or CTD-like syndromes for parvoviral DNA, RNA, and protein... - Automated kappa and lambda light chain mRNA expression for the assessment of B-cell clonality in cutaneous B-cell infiltrates: its utility and diagnostic applicationCynthia Magro
Department of Pathology, Division of Hematology-Oncology, Ohio State University School of Medicine and Public Health, Columbus, OH, USA
J Cutan Pathol 30:504-11. 2003..CONCLUSION: The Ventana kappa/lambda assay is a reliable, quick, and inexpensive way to determine B-cell clonality in cutaneous lymphoid infiltrates in paraffin-embedded formalin-fixed tissue... - De novo intraepidermal epithelioid melanocytic dysplasia as a marker of the atypical mole phenotype -- a clinical and pathological study of 75 patientsMandi Sachdeva
College of Medicine and Public Health, The Ohio State University, Columbus, 43210, USA
J Cutan Pathol 32:622-8. 2005..CONCLUSIONS: De novo intraepidermal epithelioid melanocytic dysplasia is a distinct entity associated with an atypical mole phenotype and a personal and/or family history of melanoma... - Epstein-Barr virus- and human herpesvirus 8-associated primary cutaneous plasmablastic lymphoma in the setting of renal transplantationShannon Verma
College of Medicine and Public Health, The Ohio State University, OH 43210-1218, USA
J Cutan Pathol 32:35-9. 2005..CONCLUSION: This case suggests a possible role of both viruses in the pathogenesis of PBL in sites other than the oral cavity and expands the spectrum of post-transplantation lymphoproliferative disease to include PBL... - The application of a monoclonal antibody to CD62L on paraffin-embedded tissue samples in the assessment of the cutaneous T-cell infiltratesCynthia M Magro
Department of Pathology, The Ohio State University, Columbus, OH 43210, USA
J Cutan Pathol 32:12-20. 2005..A reduction in the expression of the pan T-cell markers CD7 and CD62L supports an endogenous T-cell dyscrasia. Previously, clone availability for CD62L restricted its application to frozen tissue sections... - Docetaxel (taxotere) induced subacute cutaneous lupus erythematosus: report of 4 casesMichael Chen
Ohio State University College of Medicine, Columbus, Ohio 43210, USA
J Rheumatol 31:818-20. 2004.... - Pathologic quiz case: a pigmented lesion on the chest of a 77-year-old man. Superficial spreading melanoma in vertical growth phase, with a microscopic satelliteRuchi G Sachdev
Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, USA
Arch Pathol Lab Med 127:e365-6. 2003 - The utility of the in situ detection of T-cell receptor Beta rearrangements in cutaneous T-cell-dominant infiltratesCynthia M Magro
Department of Pathology, Ohio State University, Columbus, OH, USA
Diagn Mol Pathol 12:133-41. 2003..In conclusion, RT in situ PCR for TCRbeta, which can be done on formalin-fixed biopsies and allows direct correlation of the molecular data with the histology, is a useful adjunctive test in the differentiation of CTCL from its mimics... - Clonality in the setting of Sweet's syndrome and pyoderma gangrenosum is not limited to underlying myeloproliferative diseaseCynthia M Magro
Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10021, USA
J Cutan Pathol 34:526-34. 2007..The neutrophilic dermatoses encompass, among others, Sweet's syndrome (SS) and pyoderma gangrenosum (PG), which are associated with underlying systemic diseases including myeloid dyscrasias...