Thomas J Crowley

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Risky decisions and their consequences: neural processing by boys with Antisocial Substance Disorder
    Thomas J Crowley
    Substance Dependence Division, Psychiatry Department, University of Colorado Denver, Denver, Colorado, USA
    PLoS ONE 5:e12835. 2010
  2. ncbi request reprint The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, University of Colorado, Boulder, USA, and Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Addict Biol 12:200-9. 2007
  3. ncbi request reprint Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems
    Joseph T Sakai
    Department of Psychiatry, Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    Drug Alcohol Depend 88:130-7. 2007
  4. pmc A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Drug Alcohol Depend 89:34-41. 2007
  5. pmc Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescents
    Christie A Hartman
    School of Medicine at the University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 47:165-73. 2008
  6. ncbi request reprint Case-control and within-family tests for an association between conduct disorder and 5HTTLPR
    Joseph T Sakai
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA
    Am J Med Genet B Neuropsychiatr Genet 141:825-32. 2006
  7. pmc A behavioral test of accepting benefits that cost others: associations with conduct problems and callous-unemotionality
    Joseph T Sakai
    Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
    PLoS ONE 7:e36158. 2012
  8. doi request reprint Prevalence and predictors of injection drug use and risky sexual behaviors among adolescents in substance treatment
    Christian Thurstone
    Denver Health and Hospital Authority, Denver, Colorado University of Colorado Anschutz Medical Campus, Aurora, Colorado
    Am J Addict 22:558-65. 2013
  9. pmc Test of association between 10 single nucleotide polymorphisms in the oxytocin receptor gene and conduct disorder
    Joseph T Sakai
    Division of Substance Dependence, School of Medicine, University of Colorado Denver, 12469 East 17th Place, Aurora, CO 80045, USA
    Psychiatr Genet 22:99-102. 2012
  10. pmc DSM-IV conduct disorder criteria as predictors of antisocial personality disorder
    Heather L Gelhorn
    Department of Psychiatry, University of Colorado Health Sciences Center, Box C 268 35, Denver, CO 80262, USA
    Compr Psychiatry 48:529-38. 2007

Detail Information

Publications20

  1. pmc Risky decisions and their consequences: neural processing by boys with Antisocial Substance Disorder
    Thomas J Crowley
    Substance Dependence Division, Psychiatry Department, University of Colorado Denver, Denver, Colorado, USA
    PLoS ONE 5:e12835. 2010
    ..We hypothesized that, during processing of risky decisions and resulting rewards and punishments, brain activation would differ between abstinent ASD boys and comparison boys...
  2. ncbi request reprint The human protein kinase C gamma gene (PRKCG) as a susceptibility locus for behavioral disinhibition
    Isabel R Schlaepfer
    Institute for Behavioral Genetics, University of Colorado, Boulder, USA, and Department of Integrative Physiology, University of Colorado, Boulder, CO 80309, USA
    Addict Biol 12:200-9. 2007
    ..This study provides the first exploration of the PRKCG gene and its association with behavioral disinhibition and warrants further study in other larger population samples...
  3. ncbi request reprint Test of association between TaqIA A1 allele and alcohol use disorder phenotypes in a sample of adolescent patients with serious substance and behavioral problems
    Joseph T Sakai
    Department of Psychiatry, Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    Drug Alcohol Depend 88:130-7. 2007
    ....
  4. pmc A genome-wide scan for loci influencing adolescent cannabis dependence symptoms: evidence for linkage on chromosomes 3 and 9
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Drug Alcohol Depend 89:34-41. 2007
    ..Genetic risk factors account for part of the variation in the development of cannabis dependence symptoms; however, no linkage studies have been performed for cannabis dependence symptoms. This study aimed to identify such loci...
  5. pmc Item response theory analysis of DSM-IV cannabis abuse and dependence criteria in adolescents
    Christie A Hartman
    School of Medicine at the University of Colorado Health Sciences Center, 4200 East 9th Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 47:165-73. 2008
    ..different levels of severity of substance involvement, to what degree do each of the 11 abuse and dependence criteria assess adolescent cannabis problems, and do the DSM-IV items function similarly across different adolescent populations?..
  6. ncbi request reprint Case-control and within-family tests for an association between conduct disorder and 5HTTLPR
    Joseph T Sakai
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA
    Am J Med Genet B Neuropsychiatr Genet 141:825-32. 2006
    ..61; P = 0.20). These data suggest that the s-allele may confer some risk for aggressive behavior or may be in linkage disequilibrium with such an allele...
  7. pmc A behavioral test of accepting benefits that cost others: associations with conduct problems and callous-unemotionality
    Joseph T Sakai
    Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
    PLoS ONE 7:e36158. 2012
    ..Such behavioral tendencies are generally measured using self- or observer-report. We are unaware of attempts to measure this tendency with a behavioral paradigm...
  8. doi request reprint Prevalence and predictors of injection drug use and risky sexual behaviors among adolescents in substance treatment
    Christian Thurstone
    Denver Health and Hospital Authority, Denver, Colorado University of Colorado Anschutz Medical Campus, Aurora, Colorado
    Am J Addict 22:558-65. 2013
    ..To address this important research gap, this study evaluates the longitudinal prevalence and predictors of injection drug use (IDU) and sex risk behaviors among adolescents in substance treatment...
  9. pmc Test of association between 10 single nucleotide polymorphisms in the oxytocin receptor gene and conduct disorder
    Joseph T Sakai
    Division of Substance Dependence, School of Medicine, University of Colorado Denver, 12469 East 17th Place, Aurora, CO 80045, USA
    Psychiatr Genet 22:99-102. 2012
    ..004). We concluded that in this sample, 10 SNPs in the OXTR gene were not significantly associated with CD...
  10. pmc DSM-IV conduct disorder criteria as predictors of antisocial personality disorder
    Heather L Gelhorn
    Department of Psychiatry, University of Colorado Health Sciences Center, Box C 268 35, Denver, CO 80262, USA
    Compr Psychiatry 48:529-38. 2007
    ..Relationships between individual DSM-IV CD symptom criteria and persistent antisocial outcomes are discussed. These findings may be relevant to the development of DSM-V...
  11. pmc Test of association between GABRA2 (SNP rs279871) and adolescent conduct/alcohol use disorders utilizing a sample of clinic referred youth with serious substance and conduct problems, controls and available first degree relatives
    Joseph T Sakai
    Division of Substance Dependence, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    Drug Alcohol Depend 106:199-203. 2010
    ..We sought to replicate previous findings and test for an association between a single nucleotide polymorphism (SNP) in the GABRA2 gene (rs279871) and CD among adolescents...
  12. pmc Reduced cortical gray matter volume in male adolescents with substance and conduct problems
    Manish Dalwani
    Department of Psychiatry, University of Colorado Denver School of Medicine, 12469 E 17th Place, Aurora, CO 80045, USA
    Drug Alcohol Depend 118:295-305. 2011
    ..Because prefrontal cortex (PFC) is involved in planning behavior in accord with prior rewards and punishments, structural abnormalities in PFC could contribute to a person's propensity to make risky decisions...
  13. ncbi request reprint Adolescents and substance-related disorders: research agenda to guide decisions on Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-V)
    Thomas J Crowley
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO, USA
    Addiction 101:115-24. 2006
    ..Based on that adolescent literature, this paper suggests further research to help guide decisions about revising for DSM-V the SUD criteria in DSM-IV...
  14. ncbi request reprint A risk-taking "set" in a novel task among adolescents with serious conduct and substance problems
    Thomas J Crowley
    Division of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 45:175-83. 2006
    ..The authors asked whether such youths also take excessive risks in new situations without prior learning, peer pressure, or intoxication...
  15. pmc Cannabis receptor haplotype associated with fewer cannabis dependence symptoms in adolescents
    Christian J Hopfer
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 141:895-901. 2006
    ..Our findings provide evidence suggesting that a common CNR1 haplotype is associated with developing fewer cannabis dependence symptoms among adolescents who have experimented with cannabis...
  16. ncbi request reprint Inhalant use, abuse, and dependence among adolescent patients: commonly comorbid problems
    Joseph T Sakai
    Division of Substance Dependence, University of Colorado School of Medicine, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 43:1080-8. 2004
    ....
  17. ncbi request reprint Validity of transdermal alcohol monitoring: fixed and self-regulated dosing
    Joseph T Sakai
    Department of Psychiatry, Division of Substance Dependence, University of Colorado School of Medicine, Denver, Colorado 80262, USA
    Alcohol Clin Exp Res 30:26-33. 2006
    ..To study the validity of transdermal assessment of alcohol concentration measured by a lightweight, noninvasive device...
  18. ncbi request reprint The family transmission of adolescent alcohol abuse and dependence
    Christie A Hartman
    University of Colorado Health Sciences Center, Division of Substance Dependence, 4200 East 9th Avenue, Box C 268 35, Denver, Colorado 80262, USA
    J Stud Alcohol 67:657-64. 2006
    ..This study examines the familial transmission of alcohol abuse and dependence to adolescents...
  19. ncbi request reprint Review of twin and adoption studies of adolescent substance use
    Christian J Hopfer
    Division of Substance Dependence, Department of Psychiatry, University of Colorado Health Sciences Center, Denver, USA
    J Am Acad Child Adolesc Psychiatry 42:710-9. 2003
    ..To review studies of adolescent substance use and abuse with genetically informative designs...
  20. ncbi request reprint Treating adolescent heroin use
    Christian J Hopfer
    Division of Substance Dependence, University of Colorado School of Medicine, UC Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA
    J Am Acad Child Adolesc Psychiatry 42:609-11. 2003