James J Crowley

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. pmc Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice
    James J Crowley
    Department of Genetics, University of North Carolina, Genomic Medicine Building, CB 7264, Chapel Hill, NC 27599 7264, USA
    Mamm Genome 23:322-35. 2012
  2. pmc Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice
    J J Crowley
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Pharmacogenomics J 12:147-55. 2012
  3. doi request reprint The neuregulin 1 promoter polymorphism rs6994992 is not associated with chronic schizophrenia or neurocognition
    James J Crowley
    Department of Genetics, University of North Carolina at Chapel Hill, North Carolina 27599 7264, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1298-300. 2008
  4. pmc No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition
    Thomas I Konneker
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7264, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1115-7. 2010
  5. ncbi request reprint Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence
    Rachel J Smith
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Med Genet B Neuropsychiatr Genet 133:105-9. 2005
  6. ncbi request reprint Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test
    James J Crowley
    Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Psychopharmacology (Berl) 183:257-64. 2005
  7. ncbi request reprint A functional prodynorphin promoter polymorphism and opioid dependence
    Riju Ray
    Department of Pharmacology, University of Pennsylvania, Philadelphia, 19104, USA
    Psychiatr Genet 15:295-8. 2005

Detail Information

Publications7

  1. pmc Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice
    James J Crowley
    Department of Genetics, University of North Carolina, Genomic Medicine Building, CB 7264, Chapel Hill, NC 27599 7264, USA
    Mamm Genome 23:322-35. 2012
    ....
  2. pmc Antipsychotic-induced vacuous chewing movements and extrapyramidal side effects are highly heritable in mice
    J J Crowley
    Department of Genetics, University of North Carolina, Chapel Hill, NC 27599 7264, USA
    Pharmacogenomics J 12:147-55. 2012
    ..Murine VCMs are a face valid animal model of antipsychotic-induced TD, and heritability estimates from this study support the feasibility of mapping of susceptibility loci for VCMs...
  3. doi request reprint The neuregulin 1 promoter polymorphism rs6994992 is not associated with chronic schizophrenia or neurocognition
    James J Crowley
    Department of Genetics, University of North Carolina at Chapel Hill, North Carolina 27599 7264, USA
    Am J Med Genet B Neuropsychiatr Genet 147:1298-300. 2008
    ..We were unable to replicate previous associations of rs6994992 with schizophrenia and, moreover, did not find significant associations with age of onset, an estimate of pre-morbid IQ, or neurocognition...
  4. pmc No association of the serotonin transporter polymorphisms 5-HTTLPR and RS25531 with schizophrenia or neurocognition
    Thomas I Konneker
    Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599 7264, USA
    Am J Med Genet B Neuropsychiatr Genet 153:1115-7. 2010
    ..67 and negative symptoms P = 0.46). We were unable to identify association of the triallelic 5-HTTLPR with schizophrenia, neurocognition, or core psychotic symptoms even at levels of significance unadjusted for multiple comparisons...
  5. ncbi request reprint Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence
    Rachel J Smith
    Department of Neuroscience, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Med Genet B Neuropsychiatr Genet 133:105-9. 2005
    ..The results indicate that polymorphisms in the novel splice variant are not associated with opioid dependence, but are in LD with other polymorphisms in OPRM1...
  6. ncbi request reprint Strain-dependent antidepressant-like effects of citalopram in the mouse tail suspension test
    James J Crowley
    Department of Pharmacology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Psychopharmacology (Berl) 183:257-64. 2005
    ..Variations in the effects of antidepressant drugs between different mouse strains are important for drug discovery and could lead to the identification of genes that predict differences in drug efficacy...
  7. ncbi request reprint A functional prodynorphin promoter polymorphism and opioid dependence
    Riju Ray
    Department of Pharmacology, University of Pennsylvania, Philadelphia, 19104, USA
    Psychiatr Genet 15:295-8. 2005
    ..We examined this polymorphism for association in our sample of 168 opioid-dependent patients and 122 ethnically and geographically matched controls...