Dane A Crossley


Affiliation: University of North Texas
Country: USA


  1. Filogonio R, Crossley D. Long term effects of chronic prenatal exposure to hypercarbia on organ growth and cardiovascular responses to adrenaline and hypoxia in common snapping turtles. Comp Biochem Physiol A Mol Integr Physiol. 2019;234:10-17 pubmed publisher
    ..These data support the hypothesis that exposure to hypercarbia during embryonic development has long term effects on organ morphology and cardiovascular responses of C. serpentina. ..
  2. Conner J, Crossley J, Elsey R, Nelson D, Wang T, Crossley D. Does the left aorta provide proton-rich blood to the gut when crocodilians digest a meal?. J Exp Biol. 2019;222: pubmed publisher
    ..Our findings do not support the hypothesis that a R-L shunt serves to deliver CO2 for the gastrointestinal system after feeding in crocodilians. ..
  3. Kirby A, Cox G, Nelson D, Heuer R, Stieglitz J, Benetti D, et al. Acute crude oil exposure alters mitochondrial function and ADP affinity in cardiac muscle fibers of young adult Mahi-mahi (Coryphaena hippurus). Comp Biochem Physiol C Toxicol Pharmacol. 2019;218:88-95 pubmed publisher
    ..However, the impact of this impairment may only be evident under periods of increased aerobic metabolic demand. ..
  4. Eme J, Crossley D. Chronic hypercapnic incubation increases relative organ growth and reduces blood pressure of embryonic American alligator (Alligator mississippiensis). Comp Biochem Physiol A Mol Integr Physiol. 2015;182:53-7 pubmed publisher
    ..This study demonstrates that phenotypic plasticity of alligator embryos incubated in high CO2 may result in either preferential organ growth, or maintenance of organ growth with reduced somatic growth. ..
  5. Crossley D, Wearing O, Platzack B, Hartzler L, Hicks J. Acute and chronic temperature effects on cardiovascular regulation in the red-eared slider (Trachemys scripta). J Comp Physiol B. 2015;185:401-11 pubmed publisher
    ..Collectively, the data suggest that red-eared slider turtles modulate (down-regulate) some cardiovascular control mechanisms during reduced ambient temperature. ..
  6. Joyce W, Crossley J, Elsey R, Wang T, Crossley D. Contribution of active atrial contraction to cardiac output in anesthetized American alligators (Alligator mississippiensis). J Exp Biol. 2018;221: pubmed publisher
    ..These findings suggest that the atria are non-essential (i.e. redundant) for ventricular filling in alligators, at least under anesthesia, but may serve as important volume reservoirs. ..
  7. Wearing O, Eme J, Rhen T, Crossley D. Phenotypic plasticity in the common snapping turtle (Chelydra serpentina): long-term physiological effects of chronic hypoxia during embryonic development. Am J Physiol Regul Integr Comp Physiol. 2016;310:R176-84 pubmed publisher
    ..Pm of three-year-old turtles was not affected by feeding or hypoxic embryonic incubation. Our findings demonstrate that physiological impacts of developmental hypoxia on embryonic reptiles continue into juvenile life. ..
  8. Tate K, Rhen T, Eme J, Kohl Z, Crossley J, Elsey R, et al. Periods of cardiovascular susceptibility to hypoxia in embryonic american alligators (Alligator mississippiensis). Am J Physiol Regul Integr Comp Physiol. 2016;310:R1267-78 pubmed publisher
  9. Nelson D, Heuer R, Cox G, Stieglitz J, Hoenig R, Mager E, et al. Effects of crude oil on in situ cardiac function in young adult mahi-mahi (Coryphaena hippurus). Aquat Toxicol. 2016;180:274-281 pubmed publisher
    ..Mean intraventricular pressures and heart rate were not significantly changed. This study suggests exposure to environmentally relevant PAH concentrations impairs aspects of cardiovascular function in mahi-mahi. ..

More Information


  1. Crossley D, Ling R, Nelson D, Gillium T, Conner J, Hapgood J, et al. Metabolic responses to chronic hypoxic incubation in embryonic American alligators (Alligator mississippiensis). Comp Biochem Physiol A Mol Integr Physiol. 2017;203:77-82 pubmed publisher
    ..Our findings suggest phenotypic changes resulting from hypoxic incubation early in incubation, in particular relative cardiac enlargement, enable embryonic alligators to sustain metabolic rate during acute hypoxic exposure. ..
  2. Nelson D, Crossley D, Elsey R, Tate K. Cardiovascular adjustments with egg temperature at 90% incubation in embryonic American alligators, Alligator mississippiensis. J Comp Physiol B. 2018;188:471-480 pubmed publisher
    ..Cardiovascular regulation through the cardiac limb of the baroreflex was not affected by temperature, despite previous studies suggesting that vagal tone is present at both low and high temperatures. ..
  3. Crossley D, Sartori M, Abe A, Taylor E. A role for histamine in cardiovascular regulation in late stage embryos of the red-footed tortoise, Chelonoidis carbonaria Spix, 1824. J Comp Physiol B. 2013;183:811-20 pubmed publisher
    ..These data indicate that histamine acts as a non-adrenergic, non-cholinergic factor, regulating the cardiovascular system of developing reptilian embryos and that its overall effects are mediated via both H1 and H2 receptor types. ..
  4. Crossley D, Crossley J, Smith C, Harfush M, Sánchez Sánchez H, Garduño Paz M, et al. Developmental cardiovascular physiology of the olive ridley sea turtle (Lepidochelys olivacea). Comp Biochem Physiol A Mol Integr Physiol. 2017;211:69-76 pubmed publisher
    ..Data indicates that olive ridley sea turtles share traits of embryonic functional cardiovascular maturation with the American alligator (Alligator mississippiensis) but not the common snapping turtle (Chelydra serpentina). ..
  5. Nelson D, Stieglitz J, Cox G, Heuer R, Benetti D, Grosell M, et al. Cardio-respiratory function during exercise in the cobia, Rachycentron canadum: The impact of crude oil exposure. Comp Biochem Physiol C Toxicol Pharmacol. 2017;201:58-65 pubmed publisher