Research Topics
| M A CroceSummaryAffiliation: University of Tennessee Country: USA Publications
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Publications
A formula for prediction of posttraumatic pneumonia based on early anatomic and physiologic parametersMartin A Croce
Department of Surgery, University of Tennessee, Memphis 38163, USA
J Trauma 54:724-9; discussion 729-30. 2003..This study was performed to develop an equation that can be applied to estimate the probability of pneumonia based on parameters collected in the early postinjury interval...
Does gender difference influence outcome?Martin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis 38163, USA
J Trauma 53:889-94. 2002..We evaluated the effect of gender on various outcomes in trauma patients...
Transfusions result in pulmonary morbidity and death after a moderate degree of injuryMartin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Trauma 59:19-23; discussion 23-4. 2005....
The appropriate diagnostic threshold for ventilator-associated pneumonia using quantitative culturesMartin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 56:931-4; discussion 934-6. 2004..The purpose of this study is to determine the optimal diagnostic threshold for VAP diagnosis using quantitative cultures of the BAL effluent...
Does optimal timing for spine fracture fixation exist?M A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Ann Surg 233:851-8. 2001..To evaluate the effect of timing of spine fracture fixation on outcome in multiply injured patients...
Impact of motorcycle helmets and state laws on society's burden: a national studyMartin A Croce
Department of Surgery University of Tennessee Health Science Center Memphis, TN, USA
Ann Surg 250:390-4. 2009..To analyze a large national database, the National Trauma Data Bank, regarding the contribution of motorcycle helmet use to outcome and the efficacy of state helmet laws...
The futility of the clinical pulmonary infection score in trauma patientsMartin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 60:523-7; discussion 527-8. 2006..In this study, we evaluated the potential use of CPIS as the sole means for diagnosis of VAP in critically injured patients...
Ventilator-associated pneumonia: an overviewJennifer M DiCocco
University of Tennessee Health Science Center, Department of Surgery, 910 Madison Ave 219, Memphis, TN 38163, USA
Expert Opin Pharmacother 10:1461-7. 2009..Following these practices will help to decrease multi-resistant strains of bacteria and can improve the morbidity and mortality of VAP...
Early and late acute respiratory distress syndrome: two distinct clinical entitiesM A Croce
Department of Surgery, Presley Regional Trauma Center, University of Tennessee, Memphis 38163, USA
J Trauma 46:361-6; discussion 366-8. 1999..Pressure-limited and non-pressure-limited ventilatory techniques have been advocated with disparate results. We hypothesized that there are two forms of ARDS, which may account for the conflicting clinical reports...
Specific abbreviated injury scale values are responsible for the underestimation of mortality in penetrating trauma patients by the injury severity scoreSusan E Rowell
Department of Surgery, Oregon Health and Science University, Portland, Oregon 97227, USA
J Trauma 71:S384-8. 2011..We hypothesized that the mechanism-based difference in mortality could be attributed to certain ISS ranges and specific AIS values by body region...
Gender-based differences in mortality in response to high product ratio massive transfusionSusan E Rowell
Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
J Trauma 71:S375-9. 2011..This has not been examined independently in women and men. A gender dichotomy in outcome after severe injury is known to exist. This study examined gender-related differences in mortality after high product ratio massive transfusion...
Variations between level I trauma centers in 24-hour mortality in severely injured patients requiring a massive transfusionCharles E Wade
Department of Surgery, and The Center for Translational Injury Research, The University of Texas Health Science Center at Houston, Houston, Texas, USA
J Trauma 71:S389-93. 2011..We hypothesized differences among centers in 24-hour mortality could predominantly be accounted for by differences in transfusion practices as well as patient characteristics...
Is ventilator-associated pneumonia in trauma patients an epiphenomenon or a cause of death?Louis J Magnotti
Department of Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA
Surg Infect (Larchmt) 5:237-42. 2004..We studied patients with less severe injuries (Injury Severity Score, ISS < 25) to determine the impact of VAP on outcomes...
A high fresh frozen plasma: packed red blood cell transfusion ratio decreases mortality in all massively transfused trauma patients regardless of admission international normalized ratioLisa M Brown
Department of Surgery, University of California, San Francisco, San Francisco, California 94143 0470, USA
J Trauma 71:S358-63. 2011..Therefore, we hypothesized that patients with elevated International Normalized Ratio (INR) on arrival to the hospital may benefit more from transfusion with a high ratio of FFP:PRBC than those with a lower INR...
Effect of high product ratio massive transfusion on mortality in blunt and penetrating trauma patientsSusan E Rowell
Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
J Trauma 71:S353-7. 2011..This study was performed to determine whether mortality after high product ratio massive transfusion is different in blunt and penetrating trauma patients...
Acute respiratory distress syndrome in blunt trauma: identification of independent risk factorsPreston R Miller
Department of Surgery, The University of Tennessee Health Science Center, Memphis 38163, USA
Am Surg 68:845-50; discussion 850-1. 2002..Improvement in understanding of which patients are actually at risk may allow for advances in treatment as well as prevention in the future...
The predictive value of preliminary bacterial colony counts from bronchoalveolar lavage in critically ill trauma patientsEric W Mueller
Department of Pharmacy, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Am Surg 69:749-55; discusiion 755-6. 2003..Empiric antibiotics should be continued until the final results are available in those patients with NG BALs...
Identification of early predictors for post-traumatic pneumoniaM A Croce
Department of Surgery, Presley Regional Trauma Center, University of Tennessee, Memphis 38163, USA
Am Surg 67:105-10. 2001..Prompt identification of this high-risk group of patients allows prognostic considerations relative to patient management schemes and targets populations for prophylactic measures or immunomodulation...
Effect from multiple episodes of inadequate empiric antibiotic therapy for ventilator-associated pneumonia on morbidity and mortality among critically ill trauma patientsEric W Mueller
Department of Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 58:94-101. 2005..These findings reinforce the importance of developing and refining a unit-specific pathway for the empiric management of VAP...
Gastric and extragastric actions of the histamine antagonist ranitidine during posttraumatic sepsisR M Stewart
Department of Surgery Trauma Division, University of Tennessee Health Science Center, Memphis 38163
Surgery 117:68-82. 1995..A few reports suggest that ranitidine might also bind to extragastric sites and/or act as an immunomodulator. The potential effects on posttraumatic sepsis are unknown...
Prostanoids: early mediators in the secondary injury that develops after unilateral pulmonary contusionK A Davis
Department of Surgery, University of Tennessee, Memphis, USA
J Trauma 46:824-31; discussion 831-2. 1999..We have previously shown a sequence of events after unilateral pulmonary contusion that suggests the release of blood-borne prostanoid mediators and that culminates in refractory bilateral pulmonary failure...
The effect of bacterial contamination on neointimal hyperplasia in vascular graftsNorma M Edwards
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Am Surg 72:1168-74; discussion 1174-5. 2006..aeruginosa than common Gram-positive organisms. Increased NH from subclinical infection may be a significant factor contributing to late graft failures...
Blunt aortic injury with concomitant intra-abdominal solid organ injury: treatment priorities revisitedJohn M Santaniello
Department of Surgery, Loyola University Medical Center, Stritch School of Medicine, Maywook, Illinois 60153, USA
J Trauma 53:442-5; discussion 445. 2002..We evaluated the safety of nonoperative management (NOM) of blunt L/S injuries in patients undergoing acute BAI repair with bypass...
Accuracy of methods to estimate ionized and "corrected" serum calcium concentrations in critically ill multiple trauma patients receiving specialized nutrition supportRoland N Dickerson
Department of Pharmacy, University of Tennessee Health Science Center, 26 South Dunlap St, Room 210, Memphis, TN 38163, USA
JPEN J Parenter Enteral Nutr 28:133-41. 2004..Predictive methods for estimating ionized or corrected serum concentrations should not be used. Direct measurement of serum iCa concentration is indicated for assessing calcium status for this population...
ARDS after pulmonary contusion: accurate measurement of contusion volume identifies high-risk patientsP R Miller
Department of Surgery, University of Tennessee at Memphis, 38163, USA
J Trauma 51:223-8; discussion 229-30. 2001..With this project, we examine a method of accurately measuring degree of PC by quantifying contusion volume relative to pulmonary function and outcome...
A normal platelet count may not be enough: the impact of admission platelet count on mortality and transfusion in severely injured trauma patientsLisa M Brown
Department of Surgery, University of California, San Francisco, California, USA
J Trauma 71:S337-42. 2011..The purpose of this study was to examine the relationship between admission platelet count and outcomes after trauma...
Staged management of giant abdominal wall defects: acute and long-term resultsT Wright Jernigan
Department of Surgery, University of Tennessee Health Science Center, 956 Court Avenue, Suite G228, Memphis, TN 38163, USA
Ann Surg 238:349-55; discussion 355-7. 2003..Because of the low recurrent hernia rate and avoidance of permanent mesh, the components separation technique is the procedure of choice for definitive abdominal wall reconstruction...
Minimal aortic injury: a lesion associated with advancing diagnostic techniquesA K Malhotra
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 51:1042-8. 2001..Recently, we have used nonoperative therapy as definitive treatment for patients with MAI. The current study examines our institutional experience with these patients from July 1994 to June 2000...
Duration of antibiotic therapy for penetrating abdominal trauma: a prospective trialT C Fabian
Department of Surgery, University of Tennessee, Memphis 38163
Surgery 112:788-94; discussion 794-5. 1992..However, with colon injury and significant degree of injury, abdominal trauma index (ATI) more than 25, concern exists that short-term treatment is not adequate...
Failures of splenic nonoperative management: is the glass half empty or half full?T K Bee
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Trauma 50:230-6. 2001..Recently reported NOM rates approximate 60%, with failure rates of 10% to 15%. This study evaluated our failures of NOM for BSI relative to these clinical factors...
Multiplicity of solid organ injury: influence on management and outcomes after blunt abdominal traumaAjai K Malhotra
Department of Surgery, Medical College of Virginia, Virginia Commonwealth University, Richmond, 23298, USA
J Trauma 54:925-9. 2003..The current study was undertaken to examine how concomitant injury to liver and spleen after blunt abdominal trauma affects management and outcomes...
Prosthetic vascular conduit in contaminated fields: a new technology to decrease ePTFE infectionsPeter E Fischer
College of Medicine, Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Am Surg 74:524-8; discussion 528-9. 2008..In vitro, the grafts provide a slow elution of antibiotics that provide resistance from infection by SA and SE for up to 2 weeks after graft insertion...
Aerosolized ceftazidime for prevention of ventilator-associated pneumonia and drug effects on the proinflammatory response in critically ill trauma patientsG Christopher Wood
Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee, Memphis 38163, USA
Pharmacotherapy 22:972-82. 2002..02). CONCLUSIONS: Aerosolized ceftazidime decreased the frequency of VAP in critically ill trauma patients, without adversely affecting ICU flora. Aerosolized ceftazidime also may attenuate the proinflammatory response in the lung...
Blunt renal artery injury: incidence, diagnosis, and managementL M Bruce
Presley Regional Trauma Center, Department of Surgery, University of Tennessee at Memphis, 38163, USA
Am Surg 67:550-4; discussion 555-6. 2001..Nonoperative management of unilateral injuries can be successful with a 6 per cent risk for developing renovascular hypertension. The role of endovascular stenting is promising, and further study is necessary...
Blunt cerebrovascular injuries: diagnosis and treatmentP R Miller
Department of Surgery, University of Tennessee at Memphis, 38163, USA
J Trauma 51:279-85; discussion 285-6. 2001..Vertebral artery injury (VAI) has been thought both rare and of questionable significance. Incidence, associated injury patterns, and outcomes were examined during a period of aggressive screening (four-vessel angiography)...
Impact of airbags on a Level I trauma center: injury patterns, infectious morbidity, and hospital costsRegan F Williams
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 206:962-8; discussion 968-9. 2008..We hypothesized that airbag use would be related to decreased injury severity of motor vehicle collision survivors admitted to a Level I trauma center, leading to a decrease in infectious morbidity and hospital resource use...
Use of presumptive antibiotics following tube thoracostomy for traumatic hemopneumothorax in the prevention of empyema and pneumonia--a multi-center trialRobert A Maxwell
Department of Surgery, University of Tennessee Chattanooga Unit, Chattanooga, Tennessee, 37403, USA
J Trauma 57:742-8; discussion 748-9. 2004..To determine whether presumptive antibiotics reduce the risk of empyema or pneumonia following tube thoracostomy for traumatic hemopneumothorax...
Current issues in traumaTimothy C Fabian
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Curr Probl Surg 39:1160-244. 2002
Combination therapy that targets secondary pulmonary changes after abdominal traumaK A Davis
Department of Surgery, University of Tennessee, Memphis 38163, USA
Shock 15:479-84. 2001..This suggests that combination therapy may have beneficial effects on the lung after trauma...
Establishing a laparoscopic bariatric program in a safety net hospitalA K Madan
Department of Surgery, University of Tennessee Health Science Center, 956 Court Avenue, Room G210, Memphis, TN 38163, USA
Surg Endosc 21:801-4. 2007..The authors have recently initiated a program at a safety net hospital. This investigation hypothesizes that a laparoscopic bariatric program can be established at a safety net hospital with good clinical and financial results...
Antibiotic-coated ePTFE decreases graft colonization and neointimal hyperplasiaPeter E Fischer
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Surg Res 156:199-204. 2009..Thus, we hypothesized that the coated grafts would resist infection and have decreased neointimal hyperplasia when used in vivo in a large animal model...
The real risk of splenectomy after discharge home following nonoperative management of blunt splenic injuryBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 66:1531-6; discussion 1536-8. 2009..The purpose of this study was to analyze, using population-based data, the 180-day risk of splenectomy in a clinically relevant sample...
Necessity of repeat head CT and ICU monitoring in patients with minimal brain injuryTiffany K Bee
Critical Care Trauma Division, Department of General Surgery, University of Tennessee, Memphis, Tennessee 38163, USA
J Trauma 66:1015-8. 2009..In an attempt to better allocate scarce resources, we hypothesized that not only was repeat head CT unnecessary but also routine intensive care unit (ICU) monitoring of these patients with MBI and stable examinations were unnecessary...
Utility of preliminary bronchoalveolar lavage results in suspected ventilator-associated pneumoniaJoseph M Swanson
Department of Clinical Pharmacy, College of Pharmacy, The University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 65:1271-7. 2008..Our objective was to verify the predictive value of pBALs for fBALs, and evaluate the use of insignificant (1-99,999 cfu/mL) pBALs for rapid discontinuation of empirical antibiotics...
Temporary abdominal closure techniques: a prospective randomized trial comparing polyglactin 910 mesh and vacuum-assisted closureTiffany K Bee
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 65:337-42; discussion 342-4. 2008..Some advocate polyglactin mesh (MESH), while others favor vacuum-assisted closure (VAC). We performed a single institution prospective randomized trial comparing morbidity and mortality differences between MESH and VAC...
Impact of intracranial pressure monitor prophylaxis on central nervous system infections and bacterial multi-drug resistanceNathaniel F Stoikes
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Surg Infect (Larchmt) 9:503-8. 2008..We tested the hypothesis that prophylactic antibiotics do not reduce the incidence of central nervous system (CNS) infections but instead are associated with the acquisition of multi-drug resistant (MDR) bacterial infections...
Impact of gender on outcomes after blunt injury: a definitive analysis of more than 36,000 trauma patientsLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 206:984-91; discussion 991-2. 2008..In an attempt to resolve this ongoing dispute, we evaluated the effect of gender on various outcomes in the largest single institutional series of trauma patients reported in the literature after blunt injury...
New vitals after injury: shock index for the young and age x shock index for the oldBen L Zarzaur
Department of Surgery at The University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Surg Res 147:229-36. 2008..Because age negatively impacts physiological reserve, we hypothesized that age multiplied by SI (Age x SI) would be a better predictor of 48 h mortality (48 MORT) compared to heart rate (HR), systolic blood pressure (SBP), or SI...
Reduction in inadequate empiric antibiotic therapy for ventilator-associated pneumonia: impact of a unit-specific treatment pathwayLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Am Surg 74:516-22; discussion 522-3. 2008..Adherence to a unit-specific pathway for the empiric management of VAP reduces multiple IEAT episodes. By limiting IEAT episodes, resource utilization and hospital mortality are significantly decreased...
The "July phenomenon": is trauma the exception?Thomas J Schroeppel
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 209:378-84. 2009..The objective of this study was to determine if a July phenomenon existed in a Level I trauma center with an attending present at all times...
Admission ionized calcium levels predict the need for multiple transfusions: a prospective study of 591 critically ill trauma patientsLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:391-5; discussion 395-7. 2011..We hypothesized that admission iCa levels could potentially predict the need for multiple transfusions in critically ill trauma patients...
Improved survival after hemostatic resuscitation: does the emperor have no clothes?Louis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 70:97-102. 2011..To help resolve this controversy, we evaluated the temporal relationship between blood product administration and mortality in civilian trauma patients receiving MT...
Beta-adrenergic blockade and traumatic brain injury: protective?Thomas J Schroeppel
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
J Trauma 69:776-82. 2010..We hypothesize that suppression of the catecholamine surge in multiple-injured TBI patients with beta-adrenergic blockade decreases mortality...
A population-based analysis of neighborhood socioeconomic status and injury admission rates and in-hospital mortalityBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 211:216-23. 2010..We hypothesized that injury-related hospitalization rates would vary by N-SES and that N-SES would be related to in-hospital mortality...
Long-term survival and return on investment after nonneurologic injury: implications for the elderly trauma patientBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 69:93-8. 2010..The purpose of this study was to evaluate the cost per 2-year survivor stratified by age after moderate- to severe-nonneurologic injury...
Identifying life-threatening shock in the older injured patient: an analysis of the National Trauma Data BankBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 68:1134-8. 2010..We hypothesized that age x SI would be a better predictor of 48-hour mortality in old patients (age, >55 years) compared with TVS, whereas for young patients (age, <or=55 years), SI would be a better predictor than TVS...
The morbidity of trauma nephrectomyNorma M Edwards
University of Tennessee Health Science Center, Department of Surgery, Memphis, TN 38163, USA
Am Surg 75:1112-7. 2009..The results from this study allow us to establish benchmarks to assess complication rates for patients who undergo TN, which can provide prognostic information and goals to improve patient outcomes...
Insurance type is a determinant of 2-year mortality after non-neurologic traumaBen L Zarzaur
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Surg Res 160:196-201. 2010..Less is known about the influence of insurance type and long-term mortality following non-NEURO-TRA. We hypothesized that NO-INS would be associated with 2-y mortality after moderate to severe injury...
A ten-year review of enterocutaneous fistulas after laparotomy for traumaPeter E Fischer
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 67:924-8. 2009..This study is the largest series of ECFs reported exclusively caused by trauma and examines the characteristics unique to this population...
Disparate response to metoclopramide therapy for gastric feeding intolerance in trauma patients with and without traumatic brain injuryRoland N Dickerson
Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
JPEN J Parenter Enteral Nutr 33:646-55. 2009..Combination therapy with erythromycin as first-line therapy for TBI trauma patients with gastric feeding intolerance is indicated if there are no contraindications or significant drug interactions...
Changes in pulmonary cytokines during antibiotic therapy for ventilator-associated pneumoniaJoseph M Swanson
Department of Clinical Pharmacy, University of Tennessee, Memphis, Tennessee 38163, USA
Surg Infect (Larchmt) 11:161-7. 2010..A major unanswered question in ventilator-associated pneumonia (VAP) management relates to patient response to therapy. We investigated the use of pulmonary cytokines as biomarkers for response to antibiotic therapy for VAP...
Efficacy of monotherapy in the treatment of Pseudomonas ventilator-associated pneumonia in patients with traumaLouis J Magnotti
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 66:1052-8; discussion 1058-9. 2009..The relevance of such "synergy" is commonly supposed but poorly supported. The purpose of this study was to evaluate the efficacy of monotherapy in the treatment of Pseudomonas VAP as measured by microbiological resolution...
Treatment of acute hypocalcemia in critically ill multiple-trauma patientsRoland N Dickerson
Departments of Pharmacy and Surgery, University of Tennessee Health Science Center, Memphis, 38163, USA
JPEN J Parenter Enteral Nutr 29:436-41. 2005..12 mmol/L). However, validated methods for the treatment of acute hypocalcemia are lacking...
Evaluation of an artificial neural network to predict urea nitrogen appearance for critically ill multiple-trauma patientsRoland N Dickerson
Department of Pharmacy, University of Tennessee Health Science Center, Memphis, 38163, USA
JPEN J Parenter Enteral Nutr 29:429-35. 2005..Computer-based simulated biologic neural network models have made significant strides in clinical medicine...
Predicting total urinary nitrogen excretion from urinary urea nitrogen excretion in multiple-trauma patients receiving specialized nutritional supportRoland N Dickerson
Department of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Nutrition 21:332-8. 2005..We investigated the accuracy of methods to estimate total urinary nitrogen (TUN) excretion from urinary urea nitrogen (UUN) excretion for patients who have multiple trauma and receive specialized nutritional support...
Candida sp. isolated from bronchoalveolar lavage: clinical significance in critically ill trauma patientsG Christopher Wood
College of Pharmacy, Department of Pharmacy, University of Tennessee Health Science Center, 26 South Dunlap, Memphis, Tennessee 38163, USA
Intensive Care Med 32:599-603. 2006..The objective of this study was to determine the clinical significance of Candida sp. isolated from BAL cultures in critically ill trauma patients...
Tetracyclines for treating multidrug-resistant Acinetobacter baumannii ventilator-associated pneumoniaG Christopher Wood
Department of Clinical Pharmacy, The University of Tennessee College of Pharmacy, 26 South Dunlap, Memphis, Tennessee 38163, USA
Intensive Care Med 29:2072-6. 2003..To report the use of tetracyclines for the treatment of multidrug-resistant Acinetobacter baumannii ventilator-associated pneumonia (VAP)...
Dose-dependent characteristics of intravenous calcium therapy for hypocalcemic critically ill trauma patients receiving specialized nutritional supportRoland N Dickerson
Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Nutrition 23:9-15. 2007..The purpose of this investigation was to evaluate the dose-dependent characteristics of intravenous calcium gluconate therapy for hypocalcemic critically ill patients...
Safety and efficacy of a graduated intravenous insulin infusion protocol in critically ill trauma patients receiving specialized nutritional supportRoland N Dickerson
Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, TN, USA
Nutrition 24:536-45. 2008....
Evaluation of a clinical pathway for ventilator-associated pneumonia: changes in bacterial flora and the adequacy of empiric antibiotics over a three-year periodG Christopher Wood
Department of Pharmacy, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Surg Infect (Larchmt) 6:203-13. 2005..The objectives of this study were to compare organisms causing VAP over a three-year period to previous data, and to determine the adequacy of the empiric antibiotic regimens...
Treatment of moderate to severe acute hypocalcemia in critically ill trauma patientsRoland N Dickerson
Department of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
JPEN J Parenter Enteral Nutr 31:228-33. 2007..However, evidence-based methods for the treatment of moderate to severe acute hypocalcemia (ionized calcium concentration [iCa] <1 mmol/L) are lacking...
Lactobacillus species as a cause of ventilator-associated pneumonia in a critically ill trauma patientG Christopher Wood
Department of Clinical Pharmacy, College of Pharmacy, University of Tennessee, Memphis 38163, USA
Pharmacotherapy 22:1180-2. 2002..The infection was treated successfully with 14 days of intravenous vancomycin. Based on this case, Lactobacillus should be considered a possible cause of ventilator-associated pneumonia in immunocompetent, critically ill patients...
The utility of serial computed tomography imaging of blunt splenic injury: still worth a second look?Jordan A Weinberg
Department of Surgery, University of Alabama at Birmingham, USA
J Trauma 62:1143-7; discussion 1147-8. 2007..The purpose of this study was to reevaluate the clinical practice of serial CT imaging within the context of an institutional protocol for the nonoperative management (NOM) of BSI...
Risk factors for late-onset nosocomial pneumonia caused by Stenotrophomonas maltophilia in critically ill trauma patientsScott D Hanes
Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, TN, 38163, USA
Clin Infect Dis 35:228-35. 2002..In critically ill trauma patients with late-onset ventilator-associated pneumonia and these risk factors, empiric antibiotic therapy should include agents active against S. maltophilia...
Comparison of ampicillin-sulbactam and imipenem-cilastatin for the treatment of acinetobacter ventilator-associated pneumoniaG Christopher Wood
Department of Clinical Pharmacy, The University of Tennessee College of Pharmacy, Memphis, TN, 38163, USA
Clin Infect Dis 34:1425-30. 2002..Patients generally received Amp-Sulb because of imipenem resistance. Amp-Sulb was effective in treating a small number of patients with Acinetobacter VAP; however, more data are needed...
Aerosolized ceftazidime prophylaxis against ventilator-associated pneumonia in high-risk trauma patients: results of a double-blind randomized studyJeffrey A Claridge
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
Surg Infect (Larchmt) 8:83-90. 2007..The primary objective of this study was to determine if prophylactic administration of aerosolized ceftazidime reduced the incidence of VAP in high-risk injured patients without altering the incidence of other infectious complications...
"Awake" laparoscopy for the evaluation of equivocal penetrating abdominal woundsJordan A Weinberg
Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
Injury 38:60-4. 2007..We hypothesised that, in appropriate patients, diagnostic "awake" laparoscopy (AL) could be performed under local anaesthesia in the emergency department (ED), allowing for expedited discharge and potential cost savings...
Comparison of small-intestinal submucosa and expanded polytetrafluoroethylene as a vascular conduit in the presence of gram-positive contaminationDaniel H Shell
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Ann Surg 241:995-1001; discussion 1001-4. 2005..SIS may provide a superior alternative to ePTFE as a vascular conduit for peripheral vascular surgery...
Results of the CONTROL trial: efficacy and safety of recombinant activated Factor VII in the management of refractory traumatic hemorrhageCarl J Hauser
Department of Surgery, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts 02216, USA
J Trauma 69:489-500. 2010..Traumatic coagulopathy contributes to early death by exsanguination and late death in multiple organ failure. Recombinant Factor VIIa (rFVIIa, NovoSeven) is a procoagulant that might limit bleeding and improve trauma outcomes...
Improving outcomes following penetrating colon wounds: application of a clinical pathwayPreston R Miller
Department of Surgery, The University of Tennessee Health Science Center, Memphis, 38163, USA
Ann Surg 235:775-81. 2002..The data demonstrated the need for colostomy in the face of shock and comorbidities. Institution of this pathway results in colostomy for only 7% of all colon wounds...
Associated injuries in blunt solid organ trauma: implications for missed injury in nonoperative managementPreston R Miller
Department of Surgery, University of Tennessee Health Science Center, Memphis 38163, USA
J Trauma 53:238-42; discussion 242-4. 2002..We speculate that the greater amount and/or different vector of energy transfer needed to injure the liver versus the spleen accounts for the greater rate of associated injuries to the pancreas/small bowel...
High ratios of plasma and platelets to packed red blood cells do not affect mortality in nonmassively transfused patientsChitra N Sambasivan
Division of Trauma, Critical Care and Acute Care Surgery, Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
J Trauma 71:S329-36. 2011..We aimed to determine the effect of high ratios of fresh frozen plasma (FFP) and platelets (PLT) to packed red blood cells (PRBC) in nonmassively transfused patients...
Stress ulceration requiring definitive surgery after severe traumaB L Zarzaur
Department of Surgery, The University of Tennessee Health Science Center, Memphis, USA
Am Surg 67:875-9. 2001..VA provides no benefit on rebleeding or reoperation over VP, so anatomical considerations and not rebleed rates should determine the surgical procedure...
Repeat bronchoalveolar lavage to guide antibiotic duration for ventilator-associated pneumoniaEric W Mueller
Department of Pharmacy Services, The University Hospital, Cincinnati, Ohio, USA
J Trauma 63:1329-37; discussion 1337. 2007..We sought to determine whether antibiotic duration for VAP can be safely abbreviated in trauma patients using repeat bronchoalveolar lavage (BAL)...
Comparison of intravenous ethanol versus diazepam for alcohol withdrawal prophylaxis in the trauma ICU: results of a randomized trialJordan A Weinberg
Section of Trauma, Burns, and Surgical Critical Care, Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Trauma 64:99-104. 2008..The purpose of this study was to prospectively evaluate the efficacy of intravenous ethanol compared with benzodiazepines for the prevention of AWS with particular emphasis on the sedative effects of each therapy...
Emergent pelvic fixation in patients with exsanguinating pelvic fracturesMartin A Croce
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 204:935-9; discussion 940-2. 2007..Little published information is available about its effectiveness. This study evaluated the efficacy of the POD compared with EPF in patients with life-threatening pelvic fractures...
Expedited discharge in trauma patients requiring anticoagulation for deep venous thrombosis prophylaxis: the LEAP ProgramGail G Bridges
Department of Pharmacy, Regional Medical Center at Memphis, Tennessee 38103, USA
J Trauma 54:232-5. 2003..The LMWH Expedited Anticoagulation Program (LEAP) was created with the following goals: to decrease the number of inpatient warfarin days and to reduce overall number of hospital days...
The evolution of blunt splenic injury: resolution and progressionStephanie A Savage
Department of General Surgery, Wilford Hall Medical Center, Lackland AFB, Texas, USA
J Trauma 64:1085-91; discussion 1091-2. 2008..Our hypothesis was that time to healing is related to severity of BSI...
Penetrating rectal trauma: management by anatomic distinction improves outcomeJordan A Weinberg
University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 60:508-13; discussion 513-14. 2006..Management by anatomic distinction allows for omission of colostomy in most IP injuries and select EP injuries, while diminishing the risk of retrorectal abscess in EP injuries with the judicious application of presacral drainage...
Tobramycin bladder irrigation for treating a urinary tract infection in a critically ill patientG Christopher Wood
Ann Pharmacother 38:1318-9. 2004
The real predictors of disposition in patients with spinal cord injuriesJeffrey A Claridge
MetroHealth Medical Center, Case Western Reserve University School of Medicine, Rm H939 Hamann Bldg, 2500 MetroHealth Drive, Cleveland, OH 44109 1998, USA
J Trauma 60:178-86. 2006..Our hypothesis was that commercial insurance (CI) would be the greatest influence of hospital disposition...
Antithrombotic therapy and endovascular stents are effective treatment for blunt carotid injuries: results from longterm followupNorma M Edwards
Department of Surgery, University of Tennessee Health Science Center, Memphis, TN 38163, USA
J Am Coll Surg 204:1007-13; discussion 1014-5. 2007..This is the first study to assess longterm efficacy of various therapeutic approaches...
Diagnosis and management of blunt abdominal solid organ injuryThomas J Schroeppel
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Curr Opin Crit Care 13:399-404. 2007..Operative interventions need to occur expeditiously in hemodynamically unstable patients with hepatic and splenic injuries...
Apoptosis and necrosis in the development of acute lung injury after hemorrhagic shockT Wright Jernigan
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Am Surg 70:1094-8. 2004..Apoptosis in cells (neutrophils, macrophages, alveolar cells) is induced within the lung after hemorrhagic shock. The role of apoptosis in pulmonary dysfunction after hemorrhagic shock has yet to be determined...
Routine follow-up imaging is unnecessary in the management of blunt hepatic injuryJordy C Cox
Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
J Trauma 59:1175-8; discussion 1178-80. 2005..Follow-up scans are indicated for patients who develop signs or symptoms suggestive of hepatic abnormality...
Diagnostic laparoscopy for the evaluation of occult diaphragmatic injury following penetrating thoracoabdominal traumaBenjamin S Powell
Department of Surgery, University of Tennessee Health Science Centre, Memphis, Tennessee
Injury 39:530-4. 2008....
