Research Topics
| LINDSEY ANN CRISWELLSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Genetic risk factors for thrombosis in systemic lupus erythematosusRachel Kaiser
UCSF Division of Rheumatology, San Francisco, CA 94143, USA
J Rheumatol 39:1603-10. 2012..Thrombosis is a serious complication of systemic lupus erythematosus (SLE). We investigated whether genetic variants implicated in thrombosis pathways are associated with thrombosis among 2 ethnically diverse SLE cohorts...
Emerging patterns of genetic overlap across autoimmune disordersCorinne Richard-Miceli
University of California San Francisco, Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, Parnassus Avenue, San Francisco, CA 94143, USA
Genome Med 4:6. 2012....- Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis dataChristopher I Amos
Departments of Epidemiology and Biomathematics, University of Texas, MD Anderson Cancer Center, 1155 Pressler Street, Houston, Texas 77030, USA
BMC Proc 3:S2. 2009..Several questions could be addressed using the data, including analysis of genetic associations using single SNPs or haplotypes, as well as gene-gene and genetic analysis of SNPs for qualitative and quantitative factors... - Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traitsChristopher I Amos
Departments of Epidemiology and Biomathematics, University of Texas, Anderson Cancer Center, 1155 Pressler Street, Unit 1340, Houston, Texas 77030, USA
BMC Proc 1:S3. 2007.... - Genome-wide single-nucleotide polymorphism linkage analyses of quantitative rheumatoid arthritis phenotypes in Caucasian NARAC familiesKimberly E Taylor
University of California, San Francisco, Rosalind Russell Medical Research Center for Arthritis, 374 Parnassus Avenue, Box 0500, San Francisco, California 94143, USA
BMC Proc 1:S105. 2007.... - Conditional analysis of the major histocompatibility complex in rheumatoid arthritisKimberly E Taylor
The Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, 374 Parnassus Ave, San Francisco, California 94143 USA
BMC Proc 3:S36. 2009..001). This supports the presence of significant effects on RA susceptibility in the MHC in addition to the shared epitope... - Anticitrullinated protein antibody (ACPA) in rheumatoid arthritis: influence of an interaction between HLA-DRB1 shared epitope and a deletion polymorphism in glutathione S-transferase in a cross-sectional studyTed R Mikuls
Omaha Veterans Affairs Medical Center and Nebraska Arthritis Outcomes Research Center, University of Nebraska Medical Center, 986270 Nebraska Medical Center, Omaha, NE 68198 6270, USA
Arthritis Res Ther 12:R213. 2010..The purpose of this study was to examine the associations of GSTM1-null with ACPA positivity in RA and to assess for evidence of interaction between GSTM1 and HLA-DRB1 shared epitope (SE)... - Provision of preventive health care in systemic lupus erythematosus: data from a large observational cohort studyJinoos Yazdany
Division of Rheumatology, University of California, San Francisco, and General Clinical Research Center, Moffit Hospital, UCSF Box 0920, San Francisco, CA 94143 0920, USA
Arthritis Res Ther 12:R84. 2010..We compared the receipt of these services in SLE to the general population, and identified subgroups of patients who were less likely to receive these services... - Gene discovery in rheumatoid arthritis highlights the CD40/NF-kappaB signaling pathway in disease pathogenesisLindsey A Criswell
Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
Immunol Rev 233:55-61. 2010..These genetic discoveries shed light on underlying disease mechanisms in RA and provide targets for the development of novel diagnostic and therapeutic tools for future use in this chronic inflammatory disorder... 
The genetic contribution to systemic lupus erythematosusLindsey A Criswell
Department of Medicine, University of California, San Francisco, CA, USA
Bull NYU Hosp Jt Dis 66:176-83. 2008....- Dissecting the heterogeneity of rheumatoid arthritis through linkage analysis of quantitative traitsLindsey A Criswell
University of California, San Francisco, CA 94143, USA
Arthritis Rheum 56:58-68. 2007..To dissect the heterogeneity of rheumatoid arthritis (RA) through linkage analysis of quantitative traits, specifically, IgM rheumatoid factor (IgM-RF) and anti-cyclic citrullinated peptide (anti-CCP) autoantibody titers... - Smoking interacts with genetic risk factors in the development of rheumatoid arthritis among older Caucasian womenL A Criswell
Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, CA, USA
Ann Rheum Dis 65:1163-7. 2006..To determine whether the impact of tobacco exposure on rheumatoid arthritis (RA) risk is influenced by polymorphisms at the HLA-DRB1 and glutathione S-transferase M1 (GSTM1) loci... - Influence of male sex on disease phenotype in familial rheumatoid arthritisDamini Jawaheer
University of California, Los Angeles, USA
Arthritis Rheum 54:3087-94. 2006..Thus, other genetic or nongenetic factors also contribute to sex differences in the RA phenotype... - The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanerceptLindsey A Criswell
Rosalind Russell Medical Research Center for Arthritis, University of California, San Francisco, CA, USA
Arthritis Rheum 50:2750-6. 2004..To examine the roles of specific genetic polymorphisms as predictors of response to treatment of early rheumatoid arthritis (RA)... - Clinical and genetic risk factors for pneumonia in systemic lupus erythematosusBrent W Kinder
Division of Rheumatology, University of California San Francisco, 374 Parnassus Avenue, San Francisco, CA 94143, USA
Arthritis Rheum 56:2679-86. 2007.... - Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosusAimee O Hersh
University of California, San Francisco, CA, USA
Arthritis Rheum 61:13-20. 2009..To compare differences in long-term outcome between adults with childhood-onset (age at diagnosis <18 years) systemic lupus erythematosus (SLE) and with adult-onset SLE... - Work loss and work entry among persons with systemic lupus erythematosus: comparisons with a national matched sampleEdward Yelin
Rosalind Russell Medical Research Center for Arthritis, University of California, San Francisco, CA 94143, USA
Arthritis Rheum 61:247-58. 2009.... - Analysis of maternal-offspring HLA compatibility, parent-of-origin effects, and noninherited maternal antigen effects for HLA-DRB1 in systemic lupus erythematosusPaola G Bronson
University of California, Berkeley, California 94720 7356, USA
Arthritis Rheum 62:1712-7. 2010..Thus, we investigated maternal-offspring HLA compatibility, parent-of-origin effects, and NIMA effects at DRB1 in SLE... - Cardiovascular and disease-related predictors of depression in systemic lupus erythematosusLaura J Julian
Department of Medicine, University of California, San Francisco, 3333 California Street, Suite 270, San Francisco, CA 94143 0920, USA
Arthritis Care Res (Hoboken) 63:542-9. 2011..In this study, history of cardiovascular events, cardiovascular risk factors, and SLE disease-related factors were evaluated as longitudinal predictors of depression in a large cohort of patients with SLE... - European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosusSharon A Chung
Division of Rheumatology, University of California, San Francisco, CA 94143 0500, USA
Arthritis Rheum 60:2448-56. 2009..To determine whether genetic substructure in European-derived populations is associated with specific manifestations of systemic lupus erythematosus (SLE), including mucocutaneous phenotypes, autoantibody production, and renal disease... - Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody productionSharon A Chung
Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, United States of America
PLoS Genet 7:e1001323. 2011..Lack of strong SNP associations may suggest that other types of genetic variation or non-genetic factors such as environmental exposures have a greater impact on susceptibility to anti-dsDNA - SLE... - Obesity and its measurement in a community-based sample of women with systemic lupus erythematosusPatricia Katz
Arthritis Research Group, University of California, San Francisco, CA 94143 0920, USA
Arthritis Care Res (Hoboken) 63:261-8. 2011..To determine the prevalence of obesity and evaluate how accurately standard anthropometric measures identify obesity among women with systemic lupus erythematosus (SLE)... - Childhood-onset disease as a predictor of mortality in an adult cohort of patients with systemic lupus erythematosusAimee O Hersh
University of California, San Francisco, 94143, USA
Arthritis Care Res (Hoboken) 62:1152-9. 2010..To examine childhood-onset disease as a predictor of mortality in a cohort of adult patients with systemic lupus erythematosus (SLE)... - The role of neighborhood and individual socioeconomic status in outcomes of systemic lupus erythematosusLaura Trupin
Department of Medicine, Institute for Health Policy Studies, University of California, San Francisco, CA 94143 0920, USA
J Rheumatol 35:1782-8. 2008..To determine if neighborhood socioeconomic status (SES) is independently related to physical and mental health outcomes in systemic lupus erythematosus (SLE)... - Impact of shared epitope genotype and ethnicity on erosive disease: a meta-analysis of 3,240 rheumatoid arthritis patientsJennifer D Gorman
University of California, San Francisco, CA 94143 0500, USA
Arthritis Rheum 50:400-12. 2004..The aim of this study was to assess the association of HLA-DRB1 SE alleles and genotype with the development of bony erosions in RA by meta-analysis... - Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitisJennifer D Gorman
Division of Rheumatology, University of California San Francisco, 374 Parnassus Avenue, San Francisco, CA 94143 0500, USA
Arthritis Rheum 50:3476-84. 2004..To examine the relationship of the HLA-DRB1 shared epitope (SE) to rheumatoid vasculitis, using individual patient data (IPD) meta-analytic methods... - Impact of health maintenance organizations and fee-for-service on health care utilization among people with systemic lupus erythematosusEdward Yelin
University of California, San Francisco, CA, USA
Arthritis Rheum 57:508-15. 2007..To compare health care utilization in people with systemic lupus erythematosus (SLE) in health maintenance organizations (HMOs) and fee-for-service (FFS)... - Association of socioeconomic and demographic factors with utilization of rheumatology subspecialty care in systemic lupus erythematosusJinoos Yazdany
University of California, San Francisco, CA 94143 0920, USA
Arthritis Rheum 57:593-600. 2007.... - Medicaid and access to care among persons with systemic lupus erythematosusJoAnn Zell Gillis
University of California, San Francisco, CA 94143 0920, USA
Arthritis Rheum 57:601-7. 2007..To evaluate the associations between Medicaid insurance and distance traveled by patients to treating physicians and health care utilization for patients with systemic lupus erythematosus (SLE)... - Impact of memory impairment on employment status in persons with systemic lupus erythematosusPantelis Panopalis
Rosalind Russel Medical Research Center for Arthritis, University of California, San Francisco, San Francisco, CA 94143 0920, USA
Arthritis Rheum 57:1453-60. 2007..To assess the specific contribution of memory impairment to employment status in persons with systemic lupus erythematosus (SLE)... - Depression, medication adherence, and service utilization in systemic lupus erythematosusLaura J Julian
University of California, San Francisco, CA 94143 0920, USA
Arthritis Rheum 61:240-6. 2009..Relationships among adherence problems and service utilization (outpatient visits, emergency department visits, and hospitalizations) were also evaluated... - Frequent use of the emergency department among persons with systemic lupus erythematosusPantelis Panopalis
Rosalind Russell Medical Research Center for Arthritis, University of California, San Francisco, CA 94143 0920, USA
Arthritis Care Res (Hoboken) 62:401-8. 2010..To describe characteristics of systemic lupus erythematosus (SLE) patients who are frequent users of the emergency department and to identify predictors of frequent emergency department use... - Lack of association of the HLA-DRB1 shared epitope with rheumatoid nodules: an individual patient data meta-analysis of 3,272 Caucasian patients with rheumatoid arthritisJennifer D Gorman
University of California, San Francisco, and School of Public Health, University of California, Berkeley
Arthritis Rheum 50:753-62. 2004..The objective of this individual patient data (IPD) meta-analysis was to examine the relationship of rheumatoid nodules to the HLA-DRB1 shared epitope (SE) and to individual SE genotypes... - Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosusKimberly E Taylor
Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, California, USA
PLoS Genet 4:e1000084. 2008..We conclude that this common polymorphism of STAT4 contributes to the phenotypic heterogeneity of SLE, predisposing specifically to more severe disease... - The shared epitope and severity of rheumatoid arthritisJennifer D Gorman
Division of Rheumatology, University of California-San Francisco, San Francisco, California, USA
Rheum Dis Clin North Am 28:59-78. 2002..Ultimately, clarification of the role of the SE may be valuable for the development of specific therapies directed toward DRB1 and related targets... - Analysis of families in the multiple autoimmune disease genetics consortium (MADGC) collection: the PTPN22 620W allele associates with multiple autoimmune phenotypesLindsey A Criswell
Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Am J Hum Genet 76:561-71. 2005..DNA and clinical data for the MADGC families are available to the scientific community; these data will provide a valuable resource for the dissection of the complex genetic factors that underlie the various autoimmune phenotypes... - PTPN22: its role in SLE and autoimmunitySharon A Chung
Rosalind Russell Medical Research Center for Arthritis, Department of Medicine, University of California, San Francisco, CA, USA
Autoimmunity 40:582-90. 2007..In addition, we review the studies investigating the association between this gene and SLE, along with other autoimmune diseases... - Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosusStacy L Musone
Cardiovascular Research Institute, Department of Medicine, University of California San Francisco, San Francisco, California 94143, USA
Nat Genet 40:1062-4. 2008..These findings provide critical links between A20 and the etiology of SLE... - Recent advances in the genetics of rheumatoid arthritisChris Deighton
Rosalind Russell Medical Research Center for Arthritis, University of California-San Francisco, 374 Parnassus Avenue, Box 0500, San Francisco, CA 94143-0500, USA
Curr Rheumatol Rep 8:394-400. 2006..Lastly, a recent single nucleotide polymorphism-based genome-wide linkage analysis of multicase RA families revealed novel genomic regions that likely contain genes that predispose to RA or more specific phenotypes... - Examination of ancestry and ethnic affiliation using highly informative diallelic DNA markers: application to diverse and admixed populations and implications for clinical epidemiology and forensic medicineNan Yang
Rowe Program in Human Genetics, Departments of Biological Chemistry and Medicine, University of California, One Shields Avenue, Davis, CA, 95616 8669, USA
Hum Genet 118:382-92. 2005..99). Overall, the study demonstrates that AIMs can provide a useful adjunct to forensic medicine, pharmacogenomics and disease studies in which major ancestry or ethnic affiliation might be linked to specific outcomes... - Systematic review and metaanalysis of patient self-report versus trained assessor joint counts in rheumatoid arthritisJennifer L Barton
Division of Rheumatology, University of California, San Francisco, California 94143, USA
J Rheumatol 36:2635-41. 2009..This metaanalysis examines the degree of concordance in joint counts between trained assessors and patients with rheumatoid arthritis (RA)... - Genetics research in systemic lupus erythematosus for clinicians: methodology, progress, and controversiesRachel Kaiser
Division of Rheumatology, UCSF Department of Medicine, Rosalind Russell Medical Research Center for Arthritis, San Francisco, California 94143, USA
Curr Opin Rheumatol 22:119-25. 2010..In this review, we discuss basic issues important to understanding and contextualizing new genetic association studies. We, therefore, highlight literature related to methodology as well as recent genetic discoveries in SLE... - The inflammatory disease-associated variants in IL12B and IL23R are not associated with rheumatoid arthritisMonica Chang
Celera, Alameda, CA, USA
Arthritis Rheum 58:1877-81. 2008 - Cigarette smoking and the risk of rheumatoid arthritis among postmenopausal women: results from the Iowa Women's Health StudyLindsey A Criswell
Rosalind Russell Medical Research Center for Arthritis (LAC, University of California, San Francisco, USA
Am J Med 112:465-71. 2002..CONCLUSION: These results suggest that abstinence from smoking may reduce the risk of rheumatoid arthritis among postmenopausal women... - Health care costs and costs associated with changes in work productivity among persons with systemic lupus erythematosusPantelis Panopalis
University of California, San Francisco, CA, USA
Arthritis Rheum 59:1788-95. 2008..To estimate health care costs and costs associated with changes in work productivity among persons with systemic lupus erythematosus (SLE) in the US...
Research Grants
- Novel strategies for defining the role of HLA in SLELindsey Criswell; Fiscal Year: 2009..abstract_text> ..
- Dissecting the HLA contribution to Rheumatoid ArthritisLindsey Criswell; Fiscal Year: 2007..Finally, due to the clinical and apparent genetic heterogeneity of RA, we will study specific RA phenotypes as secondary outcomes. ..
- The Genetic Epidemiology of RA and SLELindsey Criswell; Fiscal Year: 2005DESCRIPTION (Taken from the applicant's abstract): Dr. Lindsey Ann Criswell has demonstrated a strong commitment to patient-oriented research since the beginning of her rheumatology fellowship training at the University of California, ..
- TESTING SLE CANDIDATE LOCI USING CASES AND THEIR PARENTSLindsey Criswell; Fiscal Year: 2003..Finally, the families recruited for this study will serve as a valuable resource for future genetic epidemiology studies of SLE. Therefore, the efforts of this project represent an important investment for the future. ..
- Dissecting the HLA contribution to Rheumatoid ArthritisLINDSEY ANN CRISWELL; Fiscal Year: 2010..Finally, due to the clinical and apparent genetic heterogeneity of RA, we will study specific RA phenotypes as secondary outcomes. ..