Research Topics
Genomes and GenesSpecies | Bruce C CreeSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Neuromyelitis optica: diagnosis, pathogenesis, and treatmentBruce Cree
Multiple Sclerosis Center, University of California San Francisco, 350 Parnassus Avenue, Suite 908, San Francisco, CA 94117, USA
Curr Neurol Neurosci Rep 8:427-33. 2008..This review discusses the discovery of the NMO-IgG biomarker, the identification of AQP4 as its target, the clinical applications of these advances, the pathologic implications for the anti-AQP4 antibody, and advances in NMO treatment...
Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLABruce A C Cree
Department of Neurology, University of California San Francisco, USA
Arch Neurol 66:226-33. 2009....
A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01Bruce A C Cree
Department of Neurology, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 5:e11296. 2010..Whether other major histocompatibility complex (MHC) genes contribute to MS susceptibility is controversial...
Pilot trial of low-dose naltrexone and quality of life in multiple sclerosisBruce A C Cree
Multiple Sclerosis Center at University of California, San Francisco, 94117, USA
Ann Neurol 68:145-50. 2010..To evaluate the efficacy of 4.5mg nightly naltrexone on the quality of life of multiple sclerosis (MS) patients...
Efficacy of natalizumab therapy in patients of African descent with relapsing multiple sclerosis: analysis of AFFIRM and SENTINEL dataBruce A C Cree
UCSF Multiple Sclerosis Center, Department of Neurology, University of California, San Francisco, 94117, USA
Arch Neurol 68:464-8. 2011..Because patients of African descent may be less responsive to interferon beta treatment than patients of white race/ethnicity, the efficacy of natalizumab therapy in this population is clinically important...
Emerging monoclonal antibody therapies for multiple sclerosisBruce Cree
Multiple Sclerosis Center at UCSF, San Francisco, California 94117, USA
Neurologist 12:171-8. 2006..Because of their accessibility, proteins expressed on the surface of immune system cell lineages are appealing targets for monoclonal antibody therapies...
Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosisTil Menge
Department of Neurology, University of California San Francisco, San Francisco, CA 94143-0114, USA
J Allergy Clin Immunol 116:453-9. 2005..This novel assay is a suitable and valuable method to increase accuracy of diagnosis and disease staging in MS...
Risk alleles for multiple sclerosis identified by a genomewide studyDavid A Hafler
Division of Molecular Immunology, Center for Neurologic Diseases, Department of Neurology, Brigham and Women s Hospital, and Harvard Medical School, Boston, USA
N Engl J Med 357:851-62. 2007..Multiple sclerosis has a clinically significant heritable component. We conducted a genomewide association study to identify alleles associated with the risk of multiple sclerosis...
Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trialKathleen Hawker
Department of Neurology, The Ohio State University Medical Center, Columbus, USA
Ann Neurol 66:460-71. 2009..We evaluated rituximab in adults with primary progressive MS (PPMS) through 96 weeks and safety through 122 weeks...
Research Grants
- Correlating Multiple Sclerosis Phenotypes with GenotypesBruce Cree; Fiscal Year: 2007....
