Research Topics
Species | B A C CreeSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Clinical characteristics of African Americans vs Caucasian Americans with multiple sclerosisB A C Cree
Multiple Sclerosis Center, Department of Neurology, University of California San Francisco, 350 Parnassus Ave, Suite 908, San Francisco, CA 94117, USA
Neurology 63:2039-45. 2004..African American (AA) individuals are thought to develop multiple sclerosis (MS) less frequently than Caucasian American (CA) individuals...
An open label study of the effects of rituximab in neuromyelitis opticaB A C Cree
Multiple Sclerosis Center, University of California, San Francisco 94117, USA
Neurology 64:1270-2. 2005..Seven of eight patients experienced substantial recovery of neurologic function over 1 year of average follow-up. The pretreatment median Expanded Disability Status Scale score was 7.5, and at follow-up examination was 5.5 (p = 0.013)...
Emerging monoclonal antibody therapies for multiple sclerosisBruce Cree
Multiple Sclerosis Center at UCSF, San Francisco, California 94117, USA
Neurologist 12:171-8. 2006..Because of their accessibility, proteins expressed on the surface of immune system cell lineages are appealing targets for monoclonal antibody therapies...
Response to interferon beta-1a treatment in African American multiple sclerosis patientsBruce A C Cree
Multiple Sclerosis Center, University of California, San Francisco, 94117, USA
Arch Neurol 62:1681-3. 2005..To our knowledge, it is not known to what extent treatment with interferon beta-1a will effect the MS disease course within the AA population...
Linkage and association with the NOS2A locus on chromosome 17q11 in multiple sclerosisLisa F Barcellos
Department of Neurology, School of Medicine, University of California at San Francisco, San Francisco, CA 94143 0435, USA
Ann Neurol 55:793-800. 2004..Our results provide strong evidence for linkage and association to a new candidate disease gene on chromosome 17q11 in MS and suggest that variation within NOS2A or a nearby locus contributes to disease susceptibility...
Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndromeD T Okuda
Department of Neurology, UCSF Multiple Sclerosis Center, University of California, San Francisco, San Francisco, USA
Neurology 76:686-92. 2011....
Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosisStacy J Caillier
Department of Neurology, University of California, San Francisco, CA 94143, USA
J Immunol 181:5473-80. 2008..The data underscore the power of the African American MS dataset to identify disease genes by association in a region of high linkage disequilibrium...
Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosisSergio E Baranzini
Department of Neurology, University of California, San Francisco, CA 94143 0435, USA
Hum Mol Genet 18:767-78. 2009..Gene ontology-based analysis shows a functional dichotomy between genes involved in the susceptibility pathway and those affecting the clinical phenotype...
Vitamin D in African Americans with multiple sclerosisJ M Gelfand
Department of Neurology, UCSF Multiple Sclerosis Center, San Francisco, CA, USA
Neurology 76:1824-30. 2011..To evaluate whether vitamin D is associated with multiple sclerosis (MS) status and disease severity in African Americans...
Mapping multiple sclerosis susceptibility to the HLA-DR locus in African AmericansJorge R Oksenberg
Department of Neurology, University of California at San Francisco, San Francisco, CA 94143 0435, USA
Am J Hum Genet 74:160-7. 2004..This finding is unlikely to be solely explained by admixture, since a substantial proportion of the susceptibility chromosomes from African American patients with MS displayed haplotypes consistent with an African origin...
Natalizumab dosage suspension: are we helping or hurting?Timothy W West
Multiple Sclerosis Center, University of California at San Francisco, San Francisco, CA, USA
Ann Neurol 68:395-9. 2010..Some of these flares can be clinically severe, with a high number of contrast-enhanced lesions, suggesting a possible rebound of disease activity...
Pilot trial of low-dose naltrexone and quality of life in multiple sclerosisBruce A C Cree
Multiple Sclerosis Center at University of California, San Francisco, 94117, USA
Ann Neurol 68:145-50. 2010..To evaluate the efficacy of 4.5mg nightly naltrexone on the quality of life of multiple sclerosis (MS) patients...
Modification of Multiple Sclerosis Phenotypes by African Ancestry at HLABruce A C Cree
Department of Neurology, University of California San Francisco, USA
Arch Neurol 66:226-33. 2009....
A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01Bruce A C Cree
Department of Neurology, University of California San Francisco, San Francisco, California, United States of America
PLoS ONE 5:e11296. 2010..Whether other major histocompatibility complex (MHC) genes contribute to MS susceptibility is controversial...
Refining the association of MHC with multiple sclerosis in African AmericansJoseph P McElroy
Department of Neurology, University of California, San Francisco, CA 94143, USA
Hum Mol Genet 19:3080-8. 2010....
Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measuresD T Okuda
UCSF Multiple Sclerosis Center, University of California, San Francisco, San Francisco, California 94117, USA
Brain 132:250-9. 2009....
Distinctive retinal nerve fibre layer and vascular changes in neuromyelitis optica following optic neuritisA J Green
Multiple Sclerosis Center, Department of Neurology, University of California San Francisco, San Francisco, California, USA
J Neurol Neurosurg Psychiatry 80:1002-5. 2009....
Neuromyelitis opticaBruce A C Cree
Department of Neurology, University of California San Francisco, USA
Semin Neurol 22:105-22. 2002..The history of NMO, its nosology, associations with other diseases, and current concepts of its pathogenesis and treatment is reviewed in this article...
Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directionsE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 75235, USA
Arch Neurol 62:1345-56. 2005....
A whole-genome admixture scan finds a candidate locus for multiple sclerosis susceptibilityDavid Reich
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
Nat Genet 37:1113-8. 2005..We describe here the first high-powered admixture scan, focusing on 605 African American cases and 1,043 African American controls, and report a locus on chromosome 1 that is significantly associated with multiple sclerosis...
Acute transverse myelitis: is the "idiopathic" form vanishing?Bruce A C Cree
Neurology 65:1857-8. 2005
Therapeutic considerations for disease progression in multiple sclerosis: evidence, experience, and future expectationsElliot M Frohman
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Arch Neurol 62:1519-30. 2005....
