Jacqueline N Crawley
Affiliation: University of California
Crawley J, Heyer W, LaSalle J. Autism and Cancer Share Risk Genes, Pathways, and Drug Targets. Trends Genet. 2016;32:139-146 pubmed publisher
..Understanding the genetic commonalities of autism(s) and cancer(s), with a focus on mechanistic pathways, could lead to repurposed therapeutics. ..
Kazdoba T, Leach P, Yang M, Silverman J, Solomon M, Crawley J. Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics. Curr Top Behav Neurosci. 2016;28:1-52 pubmed publisher
Gulinello M, Mitchell H, Chang Q, Timothy O Brien W, Zhou Z, Abel T, et al
. Rigor and reproducibility in rodent behavioral research. Neurobiol Learn Mem. 2018;: pubmed publisher
Crawley J. Translational animal models of autism and neurodevelopmental disorders. Dialogues Clin Neurosci. 2012;14:293-305 pubmed
..The field is now poised to employ the most robust phenotypes in the most replicable mouse models for preclinical screening of novel therapeutics. ..
Sukoff Rizzo S, Crawley J. Behavioral Phenotyping Assays for Genetic Mouse Models of Neurodevelopmental, Neurodegenerative, and Psychiatric Disorders. Annu Rev Anim Biosci. 2017;5:371-389 pubmed publisher
..Identical strategies can be employed to test hypotheses about environmental causes and gene × environment interactions. ..