James M Crawford

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. doi request reprint The origins of bladder cancer
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 88:686-93. 2008
  2. ncbi request reprint Original research in pathology: judgment, or evidence-based medicine?
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 87:104-14. 2007
  3. ncbi request reprint Evidence-based interpretation of liver biopsies
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Lab Invest 86:326-34. 2006
  4. ncbi request reprint Pathology as the enabler of human research
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 85:1058-64. 2005
  5. ncbi request reprint Development of the intrahepatic biliary tree
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0275, USA
    Semin Liver Dis 22:213-26. 2002
  6. ncbi request reprint Sustained viral response to interferon and ribavirin in liver transplant recipients with recurrent hepatitis C
    Manal F Abdelmalek
    Department of Medicine, Section of Hepatobiliary Diseases University of Florida, Gainesville, FL 32610 0214, USA
    Liver Transpl 10:199-207. 2004
  7. ncbi request reprint Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system
    Haizhen Zhu
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Gastroenterology 133:1649-59. 2007
  8. ncbi request reprint Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice
    Y Clare Zhang
    Department of Pathology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610 0275, USA
    Diabetes 52:708-16. 2003
  9. ncbi request reprint Defective Jak-Stat activation in hepatoma cells is associated with hepatitis C viral IFN-alpha resistance
    Haizhen Zhu
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, 32610, USA
    J Interferon Cytokine Res 25:528-39. 2005
  10. ncbi request reprint One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infection
    Roberto J Firpi
    Division of Gastroenterology, Hepatology, and Nutrition Section of Hepatobiliary Diseases, University of Florida, Gainesville, FL 32610 0214, USA
    Liver Transpl 10:1240-7. 2004

Collaborators

Detail Information

Publications37

  1. doi request reprint The origins of bladder cancer
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 88:686-93. 2008
    ..Effort must now be given to identifying the biological function of these novel FR genes...
  2. ncbi request reprint Original research in pathology: judgment, or evidence-based medicine?
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 87:104-14. 2007
    ..The ability of clinical faculty in academic departments of pathology to pursue original scholarship must be supported if our specialty is to retain its preeminence as an investigative scientific discipline in the age of EBM...
  3. ncbi request reprint Evidence-based interpretation of liver biopsies
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610, USA
    Lab Invest 86:326-34. 2006
    ..The remainder of our discipline rests predominantly upon the time-honored identification of disease process through the publication of narrative case series...
  4. ncbi request reprint Pathology as the enabler of human research
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0275, USA
    Lab Invest 85:1058-64. 2005
    ..It is our earnest hope that Academic Pathology can play a leading role in the remarkable advances to be made as the 21st century unfolds...
  5. ncbi request reprint Development of the intrahepatic biliary tree
    James M Crawford
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0275, USA
    Semin Liver Dis 22:213-26. 2002
    ..Thus, from the earliest time of hepatocellular bile formation beginning around the 12th week, there is a patent passage to the alimentary canal...
  6. ncbi request reprint Sustained viral response to interferon and ribavirin in liver transplant recipients with recurrent hepatitis C
    Manal F Abdelmalek
    Department of Medicine, Section of Hepatobiliary Diseases University of Florida, Gainesville, FL 32610 0214, USA
    Liver Transpl 10:199-207. 2004
    ..05). In conclusion, loss of HCV after treatment of recurrent chronic hepatitis C with interferon and ribavirin is durable, and the durability of the SVR is associated with improvement in hepatic inflammation and regression of fibrosis...
  7. ncbi request reprint Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system
    Haizhen Zhu
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, Florida, USA
    Gastroenterology 133:1649-59. 2007
    ..However, the interaction between HCV and hepatocyte innate antiviral defense systems is not understood. The aim of this study was to examine how human hepatocytes respond to HCV infection...
  8. ncbi request reprint Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice
    Y Clare Zhang
    Department of Pathology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610 0275, USA
    Diabetes 52:708-16. 2003
    ..These studies support the utility of immunoregulatory cytokine gene therapy delivered by rAAV for preventing autoimmune disease recurrence in transplant-based therapies for type 1 diabetes...
  9. ncbi request reprint Defective Jak-Stat activation in hepatoma cells is associated with hepatitis C viral IFN-alpha resistance
    Haizhen Zhu
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, 32610, USA
    J Interferon Cytokine Res 25:528-39. 2005
    ..Our study implies that long-term IFN stimulation in vitro selects cells that exhibit alterations in the host Jak-Stat signaling pathway, thereby representing a potential mechanism by which HCV resists IFN therapy...
  10. ncbi request reprint One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infection
    Roberto J Firpi
    Division of Gastroenterology, Hepatology, and Nutrition Section of Hepatobiliary Diseases, University of Florida, Gainesville, FL 32610 0214, USA
    Liver Transpl 10:1240-7. 2004
    ..A liver biopsy performed at 1 year posttransplant can help identify those patients more likely to develop progressive disease and may allow better targeting of antiviral therapy...
  11. ncbi request reprint The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1
    Samantha L Butler
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida, Gainesville, FL 32610, USA
    Lab Invest 88:78-88. 2008
    ..In conclusion, we have identified the antigen for Hep Par 1 antibody as a urea cycle enzyme CPS1. Our results should encourage further investigation of potential role that CPS1 expression plays in liver pathobiology and carcinogenesis...
  12. ncbi request reprint Therapeutic level of functional human alpha 1 antitrypsin (hAAT) secreted from murine muscle transduced by adeno-associated virus (rAAV1) vector
    Yuanqing Lu
    Department of Pharmaceutics, University of Florida College of Pharmacy, Gainesville, FL 32610, USA
    J Gene Med 8:730-5. 2006
    ..These results provide strong support for the functionality of AAT in ongoing clinical studies of muscle-directed AAT gene therapy...
  13. ncbi request reprint Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line
    Haizhen Zhu
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville 32610, USA
    Hepatology 37:1180-8. 2003
    ..Our results also suggest that IFN-alpha-induced target genes may play an important role in IFN-alpha anti-HCV activity...
  14. ncbi request reprint The pathology of cholestasis
    Melissa K Li
    University of Florida College of Medicine, Gainesville, Florida 32610 0275, USA
    Semin Liver Dis 24:21-42. 2004
    ..Most of the histological features of cholestasis are nonspecific. Hence, both practicing physician and pathologist should have sound knowledge of the pathology of cholestasis...
  15. ncbi request reprint Early histologic changes in fibrosing cholestatic hepatitis C
    Lisa R Dixon
    University of Florida, College of Medicine, Department of Pathology, Immunology, and Laboratory Medicine, Gainesville, FL 32610 0275, USA
    Liver Transpl 13:219-26. 2007
    ..When studying the evolution of these cases, the first abnormality to appear is RHCV and cholestasis, fibrosis develops soon after, and both continue to worsen until the point of allograft failure or patient death...
  16. ncbi request reprint Hepatocellular carcinoma arising from ectopic liver tissue in the pancreas
    Diana Cardona
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, 1600 SW Archer Road, Gainesville, FL 32610, USA
    Virchows Arch 450:225-9. 2007
    ..These results support that this tumor in the pancreas is hepatocellular carcinoma, most likely arising from ectopic liver tissue within the pancreas...
  17. ncbi request reprint Glucose-responsive expression of the human insulin promoter in HepG2 human hepatoma cells
    Brant R Burkhardt
    Department of Pathology, University of Florida, Gainesville, Florida 32610, USA
    Ann N Y Acad Sci 1005:237-41. 2003
    ..Our results suggest that the human insulin promoter represents a strong candidate as a robust, glucose-responsive promoter for regulated hepatic insulin production...
  18. ncbi request reprint Hepatic oval (stem) cell expression of endothelial differentiation gene receptors for lysophosphatidic acid in mouse chronic liver injury
    Yuri Y Sautin
    Department of Pathology, Immunology and Laboratory Medicine, Hepatobiliary Program, University of Florida, Gainesville, FL 32610, USA
    J Hematother Stem Cell Res 11:643-9. 2002
    ..As a result, LPA and its analogs may represent critical endogenous mediators, which regulate survival, increase motility, and modulate proliferation and differentiation of hepatocyte progenitors in regenerating liver...
  19. ncbi request reprint Hepatitic inherited metabolic disorders
    May Arroyo
    University of Florida College of Medicine, Gainesville, Florida 32610 0275, USA
    Semin Diagn Pathol 23:182-9. 2006
    ..Distinguishing features include absence of elevated serum gamma-glutamyl transpeptidase (GGT) in PFIC-1 and PFIC-2, and elevated GGT in PFIC-3. However, molecular studies are required for a confident diagnosis of the rare PFIC syndromes...
  20. ncbi request reprint Radiation pneumonitis in mice: a severe injury model for pneumocyte engraftment from bone marrow
    Neil D Theise
    Department of Pathology, New York University School of Medicine, New York, NY 10016, USA
    Exp Hematol 30:1333-8. 2002
    ..To better understand the process by which pneumocytes can be derived from bone marrow cells, we investigated the in vivo kinetics of such engraftment following lethal irradiation...
  21. ncbi request reprint Total fibrous obliteration of main portal vein and portal foam cell venopathy in chronic hepatic allograft rejection
    Dhanpat Jain
    Department of Pathology, Yale University School of Medicine, New Haven, CT 06520 8023, USA
    Arch Pathol Lab Med 128:64-7. 2004
    ..Chronic hepatic allograft rejection is characterized by arteriopathy and bile duct loss. Pathology of the portal vein or its branches is not considered to play a major role in chronic rejection...
  22. ncbi request reprint Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation
    Y Clare Zhang
    Department of Pathology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA
    Transplantation 74:1184-6. 2002
    ..Islet expression of IL-4 led to impaired metabolic function in mice receiving a marginal mass of syngeneic islets...
  23. ncbi request reprint Rab11a immunohistochemical analysis does not distinguish indefinite, low-, and high-grade dysplasia in Barrett esophagus
    Marie E Robert
    Department of Pathology, Yale University, New Haven, CT 06520, USA
    Am J Clin Pathol 124:519-27. 2005
    ..Rab11a immunoreactivity did not enhance the diagnostic assessment of dysplasia in Barrett esophagus. The previously reported positive correlation of p53 immunoreactivity with the presence of dysplasia in Barrett esophagus was confirmed...
  24. ncbi request reprint Validation of novel optical imaging technologies: the pathologists' view
    Wendy A Wells
    Dartmouth Medical School, Department of Pathology, 1 Rope Ferry Road, Hanover, New Hampshire 03755, USA
    J Biomed Opt 12:051801. 2007
    ....
  25. ncbi request reprint Combination of interferon alfa-2b and ribavirin in liver transplant recipients with histological recurrent hepatitis C
    Roberto J Firpi
    Department of Medicine, Section of Hepatobiliary Diseases, University of Florida, Gainesville, FL 32610, USA
    Liver Transpl 8:1000-6. 2002
    ..In summary, combination therapy is a reasonable antiviral option for recurrent HCV infection for established post-LT hepatitis and appears to prevent histological progression of disease if viral eradication is successful...
  26. ncbi request reprint The impact of review articles
    Catherine M Ketcham
    Department of Pathology, Immunology and Laboratory Medicine, University of Florida College of Medicine, PO Box 100275, Gainesville, FL 32610 0275, USA
    Lab Invest 87:1174-85. 2007
    ..These data are presented with the hope that authors and editors will carefully consider their respective roles in ensuring that the body of review literature will be of maximum benefit to the scientific and biomedical community...
  27. ncbi request reprint EDG receptors and hepatic pathophysiology of LPA and S1P: EDG-ology of liver injury
    Stanislav I Svetlov
    Department of Pathology, University of Florida College of Medicine, 1600 Archer Rd, P O Box 100275, Gainesville FL 32610, USA
    Biochim Biophys Acta 1582:251-6. 2002
    ..The underlying mechanisms recruited by LPA and S1P in pathogenesis of liver injury remain to be investigated...
  28. ncbi request reprint Cholesterol crystal morphology in acalculous gallbladder disease
    Kristin Landi
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut, USA
    J Clin Gastroenterol 36:364-6. 2003
    ..We investigated the morphology of biliary crystals in such patients...
  29. ncbi request reprint Utilization of acidophil bodies in the diagnosis of recurrent hepatitis C infection after orthotopic liver transplantation
    Romil Saxena
    Department of Pathology, Yale University School of Medicine, New Haven, Connecticut 06510, USA
    Mod Pathol 15:897-903. 2002
    ..Because portal tract changes in RHCV and rejection often overlap, we sought to determine whether the degree of hepatocyte acidophil body formation seen on liver biopsies could be used to distinguish between these two conditions...
  30. ncbi request reprint Adequacy of pathology resident training for employment: a survey report from the Future of Pathology Task Group
    Mary E Kass
    College of American Pathologists, Northfield, Ill, USA
    Arch Pathol Lab Med 131:545-55. 2007
    ....
  31. doi request reprint A clinical and histopathologic perspective on evolving noninvasive and invasive alternatives for liver biopsy
    Dirk J van Leeuwen
    Section of Gastroenterology and Hepatology, Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Hanover, New Hampshire 03756, USA
    Clin Gastroenterol Hepatol 6:491-6. 2008
    ....
  32. pmc Detection of colonic dysplasia in vivo using a targeted heptapeptide and confocal microendoscopy
    Pei Lin Hsiung
    Department of Pediatrics, Radiology and Microbiology and Immunology, Stanford University School of Medicine, 318 Campus Dr, Rm E 150, Stanford, California 94305, USA
    Nat Med 14:454-8. 2008
    ..This methodology represents a promising diagnostic imaging approach for the early detection of colorectal cancer and potentially of other epithelial malignancies...
  33. ncbi request reprint Can impact factor data be trusted?
    Catherine M Ketcham
    Lab Invest 88:340-1. 2008
  34. ncbi request reprint Donor T cell-derived TNF is required for graft-versus-host disease and graft-versus-tumor activity after bone marrow transplantation
    Cornelius Schmaltz
    Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Blood 101:2440-5. 2003
    ..We could not detect TNF in the serum of our transplant recipients, suggesting that T cells contribute to GVHD and GVL via membrane-bound or locally released TNF...
  35. ncbi request reprint Nomenclature of the finer branches of the biliary tree: canals, ductules, and ductular reactions in human livers
    Tania A Roskams
    Department of Pathology, University Hospitals, University of Leuven, Leuven, Belgium
    Hepatology 39:1739-45. 2004
    ....
  36. ncbi request reprint Dr Stanley Robbins
    James M Crawford
    Lab Invest 84:393. 2004
  37. pmc Detection of endogenous biomolecules in Barrett's esophagus by Fourier transform infrared spectroscopy
    Thomas D Wang
    Division of Gastroenterology, Stanford University School of Medicine, Palo Alto Veterans Affairs Health Care System, Palo Alto, CA 94304, USA
    Proc Natl Acad Sci U S A 104:15864-9. 2007
    ....