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Genomes and GenesSpecies | Carolyn J CrandallSummaryAffiliation: University of California Country: USA Publications
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Publications
Risedronate: a clinical reviewC Crandall
Department of Medicine, University of California, Los Angeles, UCLA School of Medicine, 100 UCLA Medical Plaza, Suite 250, Los Angeles, CA 90095 7023, USA
Arch Intern Med 161:353-60. 2001..Risedronate sodium has recently been approved for the prevention and treatment of postmenopausal and corticosteroid-induced osteoporosis...- Vitamin A intake and osteoporosis: a clinical reviewCarolyn Crandall
Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California 90095 7023, USA
J Womens Health (Larchmt) 13:939-53. 2004..If osteoporosis is linked with vitamin A (Vit A) A consumption, millions of people could be affected... 
Serum sex steroid levels and longitudinal changes in bone density in relation to the final menstrual periodCarolyn J Crandall
MD, MS, Department of Medicine, David Geffen School of Medicine, University of California at Los Angeles, University of California at Los Angeles Medicine GIM, 911 Broxton Avenue, 1st Floor, Los Angeles, California 90024
J Clin Endocrinol Metab 98:E654-63. 2013..21%/year slower (P = .048). The FN associations were weaker and inconsistent. Conclusions: Higher E2 levels and lower FSH levels were associated with lower rates of LS bone loss in some but not all menopausal transition phases...- Socioeconomic status over the life-course and adult bone mineral density: the Midlife in the U.S. StudyCarolyn J Crandall
Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, USA
Bone 51:107-13. 2012..Adult bone mass depends on acquisition in childhood and decline in adulthood, and may be influenced by socioeconomic conditions over the entire life course... - Socioeconomic status, race, and bone turnover in the Midlife in the US StudyC J Crandall
Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, USA
Osteoporos Int 23:1503-12. 2012..Among a group of 940 US adults, economic adversity and minority race status were associated with higher serum levels of markers of bone turnover. These results suggest that higher levels of social stress may increase bone turnover... 
Breast tenderness and breast cancer risk in the estrogen plus progestin and estrogen-alone women's health initiative clinical trialsCarolyn J Crandall
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles UCLA Medicine GIM, 911 Broxton Avenue, 1st Floor, Los Angeles, CA 90024, USA
Breast Cancer Res Treat 132:275-85. 2012..The association of CEE + MPA therapy with increased breast cancer risk was especially pronounced among women with baseline breast tenderness...- Active, but not passive cigarette smoking was inversely associated with mammographic densityLesley M Butler
Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523 1681, USA
Cancer Causes Control 21:301-11. 2010..A negative relation between mammographic density, a strong breast cancer risk factor, and active smoking would lend support for an antiestrogenic mechanism... - Is there a positive association between mammographic density and bone mineral density? Authors' responseCarolyn Crandall
Breast Cancer Res 8:404. 2006 - Association of menopausal vasomotor symptoms with increased bone turnover during the menopausal transitionCarolyn J Crandall
Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90024, USA
J Bone Miner Res 26:840-9. 2011..We conclude that among early perimenopausal and late perimenopausal women, those with VMS had higher bone turnover than those without VMS. Prior to the final menstrual period, VMS may be a marker for risk of adverse bone health... - Increases in serum estrone sulfate level are associated with increased mammographic density during menopausal hormone therapyCarolyn J Crandall
David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA
Cancer Epidemiol Biomarkers Prev 17:1674-81. 2008..Menopausal hormone therapy increases mammographic density. We determined whether increases in serum estrone sulfate (E(1)S) levels during menopausal hormone therapy predict increased mammographic density... - Presence of vasomotor symptoms is associated with lower bone mineral density: a longitudinal analysisCarolyn J Crandall
Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
Menopause 16:239-46. 2009..To determine whether women with vasomotor symptoms (VMS) have lower bone mineral density (BMD) than do women without VMS... - Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal womenCarolyn J Crandall
Department of Internal Medicine, David Geffen School of Medicine, University of California, Los Angeles, UCLA Medicine GIM, 911 Broxton Ave, 1st Floor, Los Angeles, CA 90024, USA
Breast Cancer Res 11:R51. 2009.... - New-onset breast tenderness after initiation of estrogen plus progestin therapy and breast cancer riskCarolyn J Crandall
Department of Medicine, David Geffen School of Medicine at University of California, UCLA Medicine GIM, Los Angeles, CA 90024, USA
Arch Intern Med 169:1684-91. 2009..Estrogen plus progestin therapy increases breast cancer incidence and breast tenderness. Whether breast tenderness during estrogen plus progestin therapy is associated with breast cancer risk is uncertain... - Breast tenderness after initiation of conjugated equine estrogens and mammographic density changeCarolyn J Crandall
Department of Medicine, David Geffen School of Medicine at University of California, UCLA Medicine GIM, 911 Broxton Ave, 1st Floor, Los Angeles, CA 90024, USA
Breast Cancer Res Treat 131:969-79. 2012..4 vs. 0.6% at year 1, 2.2 vs. 1.0% at year 2, P = 0.30). The new-onset of breast tenderness after initiation of CEE + MPA, but not CEE alone, is associated with greater increases in mammographic density... - Predictors of breast discomfort among women initiating menopausal hormone therapyCarolyn J Crandall
Department, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA
Menopause 17:462-70. 2010..The aim of this study was to analyze the determinants of breast discomfort among postmenopausal women initiating menopausal hormone therapy (HT)... - The association between mammographic breast density and bone mineral density in the study of women's health across the nationCarolyn J Crandall
David Geffen School of Medicine at University of California, Los Angeles, CA 90024, USA
Ann Epidemiol 17:575-83. 2007..Bone mineral density and mammographic breast density are each associated with markers of lifetime estrogen exposure. The association between mammographic breast density and bone mineral density in early perimenopausal women is unknown... - Laboratory workup for osteoporosis. Which tests are most cost-effective?Carolyn Crandall
David Geffen School of Medicine at University of California, Los Angeles, USA
Postgrad Med 114:35-8, 41-4. 2003..In this article, Dr Crandall discusses the controversies surrounding laboratory workup after diagnosis of osteoporosis and reviews two studies that suggest a cost-effective approach to screening... - Parathyroid hormone for treatment of osteoporosisCarolyn Crandall
Department of Medicine, David Geffen School of Medicine at University of California, Iris Cantor UCLA Women s Health Center, UCLA School of Medicine, 100 UCLA Medical Plaza, Suite 250, Los Angeles, CA 90095 7023, USA
Arch Intern Med 162:2297-309. 2002..Osteoporosis is a common condition associated with multiple deleterious consequences. No therapy entirely abolishes fracture risk... - Low-dose estrogen therapy for menopausal women: a review of efficacy and safetyCarolyn Crandall
Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Iris Cantor UCLA Women s Health Center, Los Angeles, California 90095 7023, USA
J Womens Health (Larchmt) 12:723-47. 2003..Recent adverse events involving research of traditional estrogen therapy have led to interest in lower-than-standard doses of menopausal estrogen therapy... - Association of breast cancer and its therapy with menopause-related symptomsCarolyn Crandall
Division of General Internal Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, 90095 7023, USA
Menopause 11:519-30. 2004..To study the relationship between current menopause status, occurrence of menopause transition during cancer treatment, and prevalence and severity of possible menopause-related symptoms... - Bone mineral density and adjuvant therapy in breast cancer survivorsC Crandall
Division of General Internal Medicine, Jonsson Comprehensive Cancer Center at UCLA, Los Angeles, CA, USA
Breast Cancer Res Treat 88:257-61. 2004..Postmenopausal BCS who had received no adjuvant therapy also had higher whole body BMD compared to similarly aged women. In contrast, hip and lumbar spine BMD values in BCS were similar to those of the population-based database... - Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions StudyCarolyn Crandall
Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
Breast Cancer Res 7:R922-8. 2005..We hypothesized that demonstration of an association between mammographic breast density and bone mineral density (BMD) would suggest a unifying underlying mechanism influencing both breast density and BMD... - Vasomotor symptom prevalence is associated with polymorphisms in sex steroid-metabolizing enzymes and receptorsCarolyn J Crandall
Division of General Internal Medicine, Department of Medicine, University of California Los Angeles, Los Angeles, California 90024, USA
Am J Med 119:S52-60. 2006..Clarification of the mechanisms of the associations and confirmation in other populations is warranted... - Association of new-onset breast discomfort with an increase in mammographic density during hormone therapyCarolyn J Crandall
Divisions of General Internal Medicine, The David Geffen School of Medicine at UCLA, University of California Los Angeles, 911 Broxton Avenue, Los Angeles, CA 90024, USA
Arch Intern Med 166:1578-84. 2006..Postmenopausal use of estrogen and progestin therapy increases breast density and breast discomfort. Whether this increase in breast density is heralded by new-onset breast discomfort is unknown... - Cross-sectional association between markers of inflammation and serum sex steroid levels in the postmenopausal estrogen/progestin interventions trialC Crandall
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California 90024, USA
J Womens Health (Larchmt) 15:14-23. 2006..Standard risk factors do not adequately capture cardiovascular risk in postmenopausal women. We sought to determine the associations between levels of sex steroids and levels of inflammatory markers in postmenopausal women... - Gender differences in osteoporosis treatment: a review of clinical researchC Crandall
Iris Cantor UCLA Women s Health Center, 100 UCLA Medical Plaza, Suite 250, Los Angeles, CA 90095 7023, USA
J Gend Specif Med 3:42-6. 2000..Further gender-comparative research regarding nonestrogenic approaches to osteoporosis is warranted... - Progestogen levels, progesterone receptor gene polymorphisms, and mammographic density changes: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density StudyEunjung Lee
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Menopause 19:302-10. 2012..Here, after adjusting for serum estrone and estrone sulfate levels, we investigated the roles of posttreatment serum progestogen increase and of progesterone receptor gene (PGR) genetic variations on changes in mammographic density... - Diabetes and femoral neck strength: findings from the Hip Strength Across the Menopausal Transition StudyShinya Ishii
Geriatric Research, Education, and Clinical Center, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
J Clin Endocrinol Metab 97:190-7. 2012..Diabetes mellitus is associated with increased hip fracture risk, despite being associated with higher bone mineral density in the femoral neck... - Bone mineral density loss in relation to the final menstrual period in a multiethnic cohort: Results from the Study of Women's Health Across the Nation (SWAN)Gail A Greendale
Division of Geriatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
J Bone Miner Res 27:111-8. 2012..8% was lost during the transmenopause. Greater BMI and African American heritage were related to slower loss rates, whereas the opposite was true of Japanese and Chinese ancestry. © 2012 American Society for Bone and Mineral Research... - Bone resorption and fracture across the menopausal transition: the Study of Women's Health Across the NationJane A Cauley
Department of Epidemiology, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USA
Menopause 19:1200-7. 2012..Bone turnover markers (BTMs) predict fracture in older women, whereas data on younger women are lacking. To test the hypothesis that BTMs measured before and after menopause predict fracture risk, we performed a cohort study of 2,305 women... - The role of serial bone mineral density testing for osteoporosisC Crandall
Department of Medicine, UCLA School of Medicine, Iris Cantor-UCLA Women's Health Center, 100 UCLA Medical Plaza, Suite 250, Los Angeles, CA 90095-7023, USA
J Womens Health Gend Based Med 10:887-95. 2001..More research is needed to confirm that this regression to the mean may apply to all densitometry techniques, antiresorptives, age groups, and genders... - Mammographic density in a multiethnic cohortLaurel A Habel
Division of Research, Kaiser Permanente, Oakland, CA 94612, USA
Menopause 14:891-9. 2007..To compare mammographic density among premenopausal and early perimenopausal women from four racial/ethnic groups and to examine density and acculturation among Japanese and Chinese women... - Physical activity and mammographic density in a cohort of midlife womenNina Oestreicher
Kaiser Permanente Division of Research, Oakland, CA 94612, USA
Med Sci Sports Exerc 40:451-6. 2008..Physical activity (PA) is one of few modifiable breast cancer risk factors. There have been few studies of the relation between PA and mammographic density, especially in multiethnic populations...