Research Topics
| Kenneth E CovinskySummaryAffiliation: University of California Country: USA Publications
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Publications
Effect of arthritis in middle age on older-age functioningKenneth E Covinsky
Department of Medicine, University of California, San Francisco, California, USA
J Am Geriatr Soc 56:23-8. 2008..To examine whether symptomatic arthritis in middle age predicts the earlier onset of functional difficulties (difficulty with activities of daily living (ADLs) and walking) that are associated with loss of independence in older persons...
Hospitalization-associated disability: "She was probably able to ambulate, but I'm not sure"Kenneth E Covinsky
Department of Medicine and Division of Geriatrics, University of California, San Francisco, San Francisco, CA 94121, USA
JAMA 306:1782-93. 2011..Finally, we describe approaches clinicians can implement to improve the quality of life of older adults who develop hospitalization-associated disability and that of their caregivers...
Depressive symptoms in middle age and the development of later-life functional limitations: the long-term effect of depressive symptomsKenneth E Covinsky
Department of Medicine, University of California, San Francisco, San Francisco VA Medical Center 181G, 4150 Clement, San Francisco, CA 94121, USA
J Am Geriatr Soc 58:551-6. 2010..To determine whether middle-aged persons with depressive symptoms are at higher risk for developing activity of daily living (ADL) and mobility limitations as they advance into older age than those without...
Chronic conditions and mortality among the oldest oldSei J Lee
San Francisco Veterans Affairs Medical Center, Health Services Research and Development Research Enhancement Award Program, San Francisco, CA 94121, USA
Am J Public Health 98:1209-14. 2008..We sought to determine whether chronic conditions and functional limitations are equally predictive of mortality among older adults...
Pain, functional limitations, and agingKenneth E Covinsky
Department of Medicine, University of California at San Francisco, 4150 Clement, San Francisco, CA 94121, USA
J Am Geriatr Soc 57:1556-61. 2009..To examine the relationship between functional limitations and pain across a spectrum of age, ranging from mid life to advanced old age...
Childhood social and economic well-being and health in older ageSandra Moody-Ayers
San Francisco VA Medical Center, San Francisco, CA 94121, USA
Am J Epidemiol 166:1059-67. 2007..14, 1.64) participants but not Latinos. These findings suggest that childhood SES affects health status through midlife but the effects may abate in late life; its effects also may be weaker in Latinos than in Whites or Blacks...
"Below average" self-assessed school performance and Alzheimer's disease in the Aging, Demographics, and Memory StudyKala M Mehta
Division of Geriatric Medicine, University of California at San Francisco, San Francisco, CA, USA
Alzheimers Dement 5:380-7. 2009..We examined whether self-assessed school performance is associated with AD beyond the effects of educational level alone...
The relationship between self-rated health and mortality in older black and white AmericansSei J Lee
Division of Geriatrics, San Francisco Veterans Affairs Medical Center, San Francisco, California 94121, USA
J Am Geriatr Soc 55:1624-9. 2007..To determine whether the association between self-rated health (SRH) and 4-year mortality differs between black and white Americans and whether education affects this relationship...
Depressive symptoms and risk of mortality in frail, community-living elderly personsKristine Yaffe
University of California, San Francisco, Departments of Psychiatry, Neurology, and Epidemiology, San Francisco, California, USA
Am J Geriatr Psychiatry 11:561-7. 2003..The authors determined whether depressive symptoms were associated with mortality in a frail, multi-ethnic cohort...
Dysthymia and depression increase risk of dementia and mortality among older veteransAmy L Byers
Departments of Psychiatry, University of California, San Francisco, USA
Am J Geriatr Psychiatry 20:664-72. 2012..To determine whether less severe depression spectrum diagnoses such as dysthymia, as well as depression, are associated with risk of developing dementia and mortality in a "real-world" setting...
Diagnosis-related group-adjusted hospital costs are higher in older medical patients with lower functional statusKenneth H Chuang
Veterans Affairs National Quality Scholars Fellowship Program Division of Geriatrics, San Francisco VA Medical Center and University of California San Francisco, San Francisco, California 94121, USA
J Am Geriatr Soc 51:1729-34. 2003....
Black-white disparities in functional decline in older persons: the role of cognitive functionSandra Y Moody-Ayers
San Francisco VA Medical Center 181G, 4150 Clement Street, San Francisco, CA 94121, USA
J Gerontol A Biol Sci Med Sci 60:933-9. 2005..Black elders have a greater frequency of functional decline than do white elders. The impact of cognitive function on explaining black-white disparities in functional decline has not been extensively explored...
Patient and caregiver characteristics associated with depression in caregivers of patients with dementiaKenneth E Covinsky
Department of Medicine, University of California, San Francisco and the San Francisco VA Medical Center, San Francisco, CA 94121, USA
J Gen Intern Med 18:1006-14. 2003..The goal of this study was to determine the patient and caregiver characteristics associated with depression among caregivers of patients with dementia...
Reports of financial disability predict functional decline and death in older patients discharged from the hospitalAlexander K Li
Veterans Affairs National Quality Scholars Fellowship Program, San Francisco, CA, USA
J Gen Intern Med 20:168-74. 2005..Therefore, we hypothesize that the inability to pay for basic needs, which we call financial disability, predicts adverse health outcomes in older patients discharged from the hospital...
The epidemiology of pain during the last 2 years of lifeAlexander K Smith
University of California, San Francisco, Veterans Affairs Medical Center, 94121, USA
Ann Intern Med 153:563-9. 2010..The epidemiology of pain during the last years of life has not been well described...
Functional limitations, socioeconomic status, and all-cause mortality in moderate alcohol drinkersSei J Lee
San Francisco Veterans Affairs Medical Center, Division of Geriatrics, Bldg 1, Room 306, Box 181G, 4150 Clement Street, San Francisco, CA 94121, USA
J Am Geriatr Soc 57:955-62. 2009..To determine whether the survival benefit associated with moderate alcohol use remains after accounting for nontraditional risk factors such as socioeconomic status (SES) and functional limitations...
Posttraumatic stress disorder and risk of dementia among US veteransKristine Yaffe
San Francisco Veterans Affairs Medical Center, San Francisco, CA 94121, USA
Arch Gen Psychiatry 67:608-13. 2010..Posttraumatic stress disorder (PTSD) is highly prevalent among US veterans because of combat and may impair cognition...
Functional impairment, race, and family expectations of deathBrie A Williams
Division of Geriatrics, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 54:1682-7. 2006..To assess the effect of functional impairment on family expectations of death and to examine how this association varies by race...
Screening mammography in older women. Effect of wealth and prognosisBrie A Williams
Division of Geriatrics, University of California, San Francisco, CA, USA
Arch Intern Med 168:514-20. 2008..This study examines the relationship between wealth and screening mammography use in older women according to life expectancy...
Mortality risk stratification in chronic kidney disease: one size for all ages?ANN M O'HARE
Department of Medicine, University of California San Francisco, VA Medical Center, San Francisco, 111J Nephrology, 4150 Clement Street, San Francisco, CA 94121, USA
J Am Soc Nephrol 17:846-53. 2006..73 m2 eGFR group...
The last 2 years of life: functional trajectories of frail older peopleKenneth E Covinsky
Division of Geriatrics, San Francisco VA Medical Center and the University ofCalifornia at San Francisco, San Francisco, California 94121, USA
J Am Geriatr Soc 51:492-8. 2003....
Functional status of elderly adults before and after initiation of dialysisManjula Kurella Tamura
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, CA 94304, USA
N Engl J Med 361:1539-47. 2009..It is unclear whether functional status before dialysis is maintained after the initiation of this therapy in elderly patients with end-stage renal disease (ESRD)...
Twenty-year depressive trajectories among older womenAmy L Byers
Department of Psychiatry, University of California, San Francisco, CA 94121, USA
Arch Gen Psychiatry 69:1073-9. 2012..Despite the frequent occurrence of depressive symptoms among older adults, especially women, little is known about the long-term course of late-life depressive symptoms...
Development and validation of a functional morbidity index to predict mortality in community-dwelling eldersElise C Carey
Division of Geriatrics, University of California San Francisco, San Francisco, California, USA
J Gen Intern Med 19:1027-33. 2004..Our objective in this study was to develop and validate a prognostic index for 2-year mortality in community-dwelling elders, based on self-reported functional status, age, and gender...
Anxiety symptoms and decline in physical function over 5 years in the health, aging and body composition studyKala M Mehta
Division of Geriatrics, Department of Psychiatry, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 55:265-70. 2007..To examine the relationship between anxiety and functional decline...
Predicting 12-month mortality for persons with dementiaRobert Newcomer
Departments of Social and Behavioral Science, University of California, San Francisco, CA 94118, USA
J Gerontol B Psychol Sci Soc Sci 58:S187-98. 2003..We develop and test a model of 12-month mortality among persons (N=3858) with organic dementia...
Recovery of activities of daily living in older adults after hospitalization for acute medical illnessCynthia M Boyd
Department of Medicine, Division of Geriatric Medicine, School of Medicine, John Hopkins University, Baltimore, Maryland 21224, USA
J Am Geriatr Soc 56:2171-9. 2008....
Additive effects of cognitive function and depressive symptoms on mortality in elderly community-living adultsKala M Mehta
Division of Geriatrics, University of California at San Francisco, 4150 Clement Street, Box 181G, San Francisco, CA 94121, USA
J Gerontol A Biol Sci Med Sci 58:M461-7. 2003..Our aim was to examine whether the combination of varying levels of cognitive function and depressive symptoms affect the risk of mortality in community-living elderly adults...
The Women's Initiative for Nonsmoking (WINS) XI: age-related differences in smoking cessation responses among women with cardiovascular diseaseDaniel M Doolan
University of California San Francisco, San Francisco, CA, USA
Am J Geriatr Cardiol 17:37-47. 2008..Clinicians should be sure to also include older smokers in smoking assessments and smoking cessation interventions...
Development and validation of an index to predict activity of daily living dependence in community-dwelling eldersKenneth E Covinsky
Department of Medicine, University of California, San Francisco, CA, USA
Med Care 44:149-57. 2006..However, few prognostic indices have been developed that stratify elders into groups at variable risk for developing ADL dependence...
Medication prescribing practices for older prisoners in the Texas prison systemBrie A Williams
Department of Medicine, University of California, San Francisco, CA, USA
Am J Public Health 100:756-61. 2010..We sought to assess appropriateness of medication prescribing for older Texas prisoners...
High occurrence of mood and anxiety disorders among older adults: The National Comorbidity Survey ReplicationAmy L Byers
Department of Psychiatry, University of California, San Francisco, San Francisco, San Francisco, CA 94121, USA
Arch Gen Psychiatry 67:489-96. 2010..Little is known about prevalence rates of DSM-IV disorders across age strata of older adults, including common conditions such as individual and coexisting mood and anxiety disorders...
Loneliness in older persons: a predictor of functional decline and deathCarla M Perissinotto
Division of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
Arch Intern Med 172:1078-83. 2012..Loneliness is a common source of distress, suffering, and impaired quality of life in older persons. We examined the relationship between loneliness, functional decline, and death in adults older than 60 years in the United States...
Subjective social status and functional decline in older adultsBonnie Chen
Department of Medicine, University of California, San Francisco, CA, USA
J Gen Intern Med 27:693-9. 2012..It is unknown whether subjective assessment of social status predicts health outcomes in older adults...
Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II-receptor antagonists in chronic kidney disease: is the evidence base relevant to older adults?ANN M O'HARE
Division of Nephrology, Department of Medicine, University of Washington and Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98108, USA
Ann Intern Med 150:717-24. 2009....
Development and validation of a prognostic index for 4-year mortality in older adultsSei J Lee
Division of Geriatrics, San Francisco Veterans Affairs Medical Center, University of California, San Francisco
JAMA 295:801-8. 2006..CONCLUSION: This prognostic index, incorporating age, sex, self-reported comorbid conditions, and functional measures, accurately stratifies community-dwelling older adults into groups at varying risk of mortality...
Loss of independence in activities of daily living in older adults hospitalized with medical illnesses: increased vulnerability with ageKenneth E Covinsky
Division of Geriatrics, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 51:451-8. 2003..To describe the changes in activities of daily living (ADL) function occurring before and after hospital admission in older people hospitalized with medical illness and to assess the effect of age on loss of ADL function...
Urinary incontinence and its association with death, nursing home admission, and functional declineJayna M Holroyd-Leduc
San Francisco VA Medical Center, San Francisco, California, USA
J Am Geriatr Soc 52:712-8. 2004..To determine whether urinary incontinence (UI) is an independent predictor of death, nursing home admission, decline in activities of daily living (ADLs), or decline in instrumental activities of daily living (IADLs)...
Relationship between health status and use of screening mammography and Papanicolaou smears among women older than 70 years of ageLouise C Walter
San Francisco Veterans Affairs Medical Center and University of California, San Francisco, San Francisco, California 94121, USA
Ann Intern Med 140:681-8. 2004..Since life expectancy is better predicted by health status than by age alone, guidelines recommend considering an older woman's general health when making screening decisions...
Beyond the prescription: medication monitoring and adverse drug events in older adultsMichael A Steinman
Division of Geriatrics, University of California San Francisco, San Francisco, California, USA
J Am Geriatr Soc 59:1513-20. 2011....
Prevalence and correlates of perceived societal racism in older African-American adults with type 2 diabetes mellitusSandra Y Moody-Ayers
San Francisco Veterans Affairs Medical Center, San Francisco, California 94121, USA
J Am Geriatr Soc 53:2202-8. 2005....
Unsteadiness reported by older hospitalized patients predicts functional declineElizabeth C Lindenberger
Division of Geriatrics, San Francisco VA Medical Center, California 94121, USA
J Am Geriatr Soc 51:621-6. 2003....
Ethnic differences in the prevalence and pattern of dementia-related behaviorsKaycee M Sink
Division of Geriatrics, University of California at San Francisco, California 94121, USA
J Am Geriatr Soc 52:1277-83. 2004....
Mortality risk and prospective medicare expenditures for persons with dementiaRobert J Newcomer
Department of Social and Behavioral Science, University of California at San Francisco, San Fransisco, California 94118, USA
J Am Geriatr Soc 53:2001-6. 2005..To determine whether an index that stratifies dementia patients into high- and low-mortality-risk groups can be effective in prospectively identifying persons with high and low expenditures...
Pitfalls of converting practice guidelines into quality measures: lessons learned from a VA performance measureLouise C Walter
Division of Geriatrics, San Francisco VA Medical Center, and the University of California, San Francisco, CA 94121, USA
JAMA 291:2466-70. 2004..Performance measures require more thoughtful specification and interpretation to avoid defining high testing rates as good quality of care regardless of who received the test, why it was performed, or whether the patient wanted it...
Cognitive impairment, depressive symptoms, and functional decline in older peopleKala M Mehta
Division of Geriatrics, Department of Internal Medicine, University of California San Francisco, 4150 Clement Street, Box 181G, San Francisco, CA 94121, USA
J Am Geriatr Soc 50:1045-50. 2002..The purpose of this study is to determine the relative contributions of cognitive impairment and depressive symptoms on decline in activity of daily living (ADL) function over 2 years in an older cohort...
Pain as a risk factor for disability or deathJames S Andrews
School of Medicine, Division of Geriatrics, University of California at San Francisco, San Francisco Veterans Affairs Medical Center, San Francisco, California
J Am Geriatr Soc 61:583-9. 2013..To determine whether pain predicts future activity of daily living (ADL) disability or death in individuals aged 60 and older...
Health-related quality of life following coronary artery bypass graft surgery in post-menopausal womenKenneth E Covinsky
Division of Geriatrics, University of California, San Francisco, and San Francisco VA Medical Center 181G, San Francisco, CA 94121, USA
J Gen Intern Med 23:1429-34. 2008..To describe the impact of coronary artery bypass graft (CABG) surgery on health related quality of life (HRQOL) in post-menopausal women...
Serum albumin concentration and clinical assessments of nutritional status in hospitalized older people: different sides of different coins?Kenneth E Covinsky
Division of Geriatrics, University of California, San Francisco, California, USA
J Am Geriatr Soc 50:631-7. 2002..Although both measures are strongly associated with prognosis, it is not clear whether they measure similar or different clinical constructs. Our goal was to assess the degree of clinical concordance between these measures...
Age and rising rates of cyclooxygenase-2 inhibitor use. Results from a national surveyMichael A Steinman
Division of Geriatrics, San Francisco VA Medical Center, University of California, San Francisco, CA, USA
J Gen Intern Med 21:245-50. 2006..Cyclooxygenase-2 (COX-2) inhibitors were widely prescribed in the years following their introduction, but little is known about the frequency and context of their use across different age groups...
Conducting high-value secondary dataset analysis: an introductory guide and resourcesAlexander K Smith
Department of Medicine, University of California, San Francisco, CA, USA
J Gen Intern Med 26:920-9. 2011..Secondary dataset analysis is a well-established methodology. Secondary analysis is particularly valuable for junior investigators, who have limited time and resources to demonstrate expertise and productivity...
Patient and caregiver characteristics and nursing home placement in patients with dementiaKristine Yaffe
University of California, San Francisco, Box 111G, 4150 Clement St, San Francisco, CA 94121, USA
JAMA 287:2090-7. 2002..Most studies have determined predictors of nursing home placement primarily according to patient or caregiver characteristics alone...
Association of older age and female sex with inadequate reach of screening flexible sigmoidoscopyLouise C Walter
Division of Geriatrics LCW, KEC, San Francisco Veterans Affairs Medical Center and the University of California, San Francisco, California 94121, USA
Am J Med 116:174-8. 2004..We assessed the frequency of inadequate reach (depth of <50 cm of the colon) in a large U.S. cohort, according to age and sex...
Differences in mortality of black and white patients enrolled in the program of all-inclusive care for the elderlyErwin J Tan
Division of Geriatrics, University of California at San Francisco, San Francisco, California, USA
J Am Geriatr Soc 51:246-51. 2003..To examine the relationship between race and mortality in frail community-dwelling older people with access to a program providing comprehensive access and coordination of services...
Octogenarians and nonagenarians starting dialysis in the United StatesManjula Kurella
Division of Nephrology, University of California, San Francisco, CA 94118 1211, USA
Ann Intern Med 146:177-83. 2007....
Donepezil for nursing home patients with dementia: a reinterpretation of the evidenceMichael A Steinman
J Am Geriatr Soc 51:132; author reply 132-3. 2003
Risk of hip fracture in disabled community-living older adultsLouise C Walter
Division of Geriatrics, San Francisco VA Medical Center and University of California at San Francisco, 94121, USA
J Am Geriatr Soc 51:50-5. 2003..Persons with these risk factors should be targeted for preventive interventions, which should include strategies for making transferring safer...
Prediction of mortality in community-living frail elderly people with long-term care needsElise C Carey
Division of General Internal Medicine, College of Medicine, Mayo Clinic, Rochester, Minnesota, USA
J Am Geriatr Soc 56:68-75. 2008..To develop and validate a prognostic index for mortality in community-living, frail elderly people...
Coronary bypass surgery and long-term cognitive declineKristine Yaffe
Ann Neurol 63:547-8. 2008
Diet monotony as a correlate of poor nutritional intake among hemodialysis patientsJennifer L Zimmerer
Division of Nephrology, MetroHealth Medical Center, Cleveland, OH 44109, USA
J Ren Nutr 13:72-7. 2003..Helping patients to identify and increase the intake of these foods may both enhance diet variety and improve nutritional status...
The relationship of indwelling urinary catheters to death, length of hospital stay, functional decline, and nursing home admission in hospitalized older medical patientsJayna M Holroyd-Leduc
Department of Medicine, University of Calgary, Canada
J Am Geriatr Soc 55:227-33. 2007..To determine the association between indwelling urinary catheterization without a specific medical indication and adverse outcomes...
Dementia, prognosis, and the needs of patients and caregiversKenneth E Covinsky
Ann Intern Med 140:573-4. 2004
Disparities between black and white patients in functional improvement after hospitalization for an acute illnessLaura P Sands
School of Nursing, Purdue University, West Lafayette, Indiana 47907, USA
J Am Geriatr Soc 53:1811-6. 2005....
Rates of acute care admissions for frail older people living with met versus unmet activity of daily living needsLaura P Sands
School of Nursing, Center on Aging and the Life Course, Purdue University, West Lafayette, Indiana 47907, USA
J Am Geriatr Soc 54:339-44. 2006..To determine whether older people who do not have help for their activity of daily living (ADL) disabilities are at higher risk for acute care admissions and whether entry into a program that provides for these needs decreases this risk...
Caregiver characteristics are associated with neuropsychiatric symptoms of dementiaKaycee M Sink
Section on Gerontology and Geriatric Medicine, School of Medicine, Wake Forest University, Winston Salem, NC 27157, USA
J Am Geriatr Soc 54:796-803. 2006..To determine whether caregiver characteristics are independently associated with neuropsychiatric symptoms of dementia (NPS) after accounting for patient characteristics...
Envisioning better approaches for dementia careKenneth E Covinsky
Ann Intern Med 145:780-1. 2006
Malnutrition and bad outcomesKenneth E Covinsky
Division of Geriatrics, University of California-San Francisco, San Francisco, Calif. USA
J Gen Intern Med 17:956-7. 2002
Late-life mortality in older Jews exposed to the Nazi regimeLiat Ayalon
School of Social Work, Bar Ilan University, Israel
J Am Geriatr Soc 55:1380-6. 2007..To evaluate the mortality risk associated with exposure to the Nazi regime 6 decades after the war...
