Helene Cousin

Summary

Affiliation: University of Massachusetts
Country: USA

Publications

  1. pmc ADAM13 function is required in the 3 dimensional context of the embryo during cranial neural crest cell migration in Xenopus laevis
    Helene Cousin
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Dev Biol 368:335-44. 2012
  2. pmc PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis
    Helene Cousin
    Department of Veterinary and Animal Sciences, University of Massachusetts, Paige Laboratory, Amherst, MA 01003, USA
    Dev Biol 319:86-99. 2008
  3. pmc Translocation of the cytoplasmic domain of ADAM13 to the nucleus is essential for Calpain8-a expression and cranial neural crest cell migration
    Helene Cousin
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Dev Cell 20:256-63. 2011
  4. pmc Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration
    Catherine McCusker
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Mol Biol Cell 20:78-89. 2009
  5. ncbi request reprint A PTP-PEST-like protein affects alpha5beta1-integrin-dependent matrix assembly, cell adhesion, and migration in Xenopus gastrula
    Helene Cousin
    Paige Laboratory, Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Dev Biol 265:416-32. 2004
  6. pmc Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae
    Le Wang
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts, United States of America
    PLoS ONE 8:e56025. 2013
  7. pmc Xenopus ADAM19 is involved in neural, neural crest and muscle development
    Russell Neuner
    Department of Veterinary and Animal Sciences, University of Massachusetts, Paige Laboratory, Room 203, 161 Holdsworth Way, Amherst 01003, USA
    Mech Dev 126:240-55. 2009
  8. pmc Mechanism of Xenopus cranial neural crest cell migration
    Dominque Alfandari
    Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, USA
    Cell Adh Migr 4:553-60. 2010
  9. pmc ADAM function in embryogenesis
    Dominique Alfandari
    Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, Paige lab Rm 203, 161 Holdsworth Way, Amherst, MA 01003, United States
    Semin Cell Dev Biol 20:153-63. 2009
  10. pmc Cloning and expression of ADAM-related metalloproteases in equine laminitis
    Michael J Coyne
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, United States
    Vet Immunol Immunopathol 129:231-41. 2009

Collaborators

Detail Information

Publications10

  1. pmc ADAM13 function is required in the 3 dimensional context of the embryo during cranial neural crest cell migration in Xenopus laevis
    Helene Cousin
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Dev Biol 368:335-44. 2012
    ..Together our results suggest that ADAM13 changes CNC interaction with the extracellular environment and that this change is necessary for their migration in vivo...
  2. pmc PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis
    Helene Cousin
    Department of Veterinary and Animal Sciences, University of Massachusetts, Paige Laboratory, Amherst, MA 01003, USA
    Dev Biol 319:86-99. 2008
    ..We propose that PACSIN2 may regulate gastrulation by controlling the population of activated alpha5beta1 integrin and cytoskeleton strength during cell movement...
  3. pmc Translocation of the cytoplasmic domain of ADAM13 to the nucleus is essential for Calpain8-a expression and cranial neural crest cell migration
    Helene Cousin
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Dev Cell 20:256-63. 2011
    ..This study shows that the cytoplasmic domain of ADAM metalloproteases can perform essential functions in the nucleus of cells and may contribute substantially to the overall function of the protein...
  4. pmc Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration
    Catherine McCusker
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Mol Biol Cell 20:78-89. 2009
    ..We propose that ADAM cleavage of cadherin-11 promotes migration by modifying its ability to support cell-cell adhesion while maintaining the membrane-bound pool of beta-catenin associated with the cadherin-11 cytoplasmic domain...
  5. ncbi request reprint A PTP-PEST-like protein affects alpha5beta1-integrin-dependent matrix assembly, cell adhesion, and migration in Xenopus gastrula
    Helene Cousin
    Paige Laboratory, Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA
    Dev Biol 265:416-32. 2004
    ..We propose that xPTP-PESTr overexpression adversely affect cell migration by preventing de-adhesion of cells from the substrate...
  6. pmc Impact of laminitis on the canonical Wnt signaling pathway in basal epithelial cells of the equine digital laminae
    Le Wang
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, Massachusetts, United States of America
    PLoS ONE 8:e56025. 2013
    ....
  7. pmc Xenopus ADAM19 is involved in neural, neural crest and muscle development
    Russell Neuner
    Department of Veterinary and Animal Sciences, University of Massachusetts, Paige Laboratory, Room 203, 161 Holdsworth Way, Amherst 01003, USA
    Mech Dev 126:240-55. 2009
    ..We further show that ADAM19 protein reduction affects somite organization, reduces 12-101 expression and perturbs fibronectin localization at the intersomitic boundary...
  8. pmc Mechanism of Xenopus cranial neural crest cell migration
    Dominque Alfandari
    Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, USA
    Cell Adh Migr 4:553-60. 2010
    ....
  9. pmc ADAM function in embryogenesis
    Dominique Alfandari
    Department of Veterinary and Animal Sciences, University of Massachusetts Amherst, Paige lab Rm 203, 161 Holdsworth Way, Amherst, MA 01003, United States
    Semin Cell Dev Biol 20:153-63. 2009
    ..The relative contribution of four subfamilies of ADAM proteins to developmental processes is the focus of this review...
  10. pmc Cloning and expression of ADAM-related metalloproteases in equine laminitis
    Michael J Coyne
    Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, United States
    Vet Immunol Immunopathol 129:231-41. 2009
    ..We conclude that increased expression of lamellar ADAMTS-4 is a common feature of laminitis consistent with a central role of the gene product in the pathophysiology of the disease...