William Couser

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. doi request reprint Basic and translational concepts of immune-mediated glomerular diseases
    William G Couser
    Division of Nephrology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    J Am Soc Nephrol 23:381-99. 2012
  2. ncbi request reprint Chronic kidney disease the promise and the perils
    William G Couser
    University of Washington, Seattle, Washington, USA
    J Am Soc Nephrol 18:2803-5. 2007
  3. ncbi request reprint Recurrent glomerulonephritis in the renal allograft: an update of selected areas
    William Couser
    Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA, USA
    Exp Clin Transplant 3:283-8. 2005
  4. ncbi request reprint Cellular and molecular biology of membranous nephropathy
    William G Couser
    Division of Nephrology, University of Washington, Seattle, Washington, USA
    J Nephrol 19:699-705. 2006
  5. ncbi request reprint Membranous nephropathy: a long road but well traveled
    William G Couser
    Division of Nephrology, University of Washington, Seattle, USA
    J Am Soc Nephrol 16:1184-7. 2005
  6. doi request reprint The contribution of chronic kidney disease to the global burden of major noncommunicable diseases
    William G Couser
    International Society of Nephrology Global Outreach Program, Brussels, Belgium
    Kidney Int 80:1258-70. 2011
  7. doi request reprint The message for World Kidney Day 2009: hypertension and kidney disease: a marriage that should be prevented
    George L Bakris
    Hypertensive Diseases Unit, Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA
    J Clin Hypertens (Greenwich) 11:144-7. 2009
  8. doi request reprint The message for World Kidney Day 2009: hypertension and kidney disease--a marriage that should be prevented
    George L Bakris
    Department of Medicine, Hypertensive Diseases Unit, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    J Hypertens 27:666-9. 2009
  9. doi request reprint Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
    Christopher J L Murray
    Institute for Health Metrics and Evaluation, Seattle 98121, WA, USA
    Lancet 380:2197-223. 2012
  10. ncbi request reprint Cellular response to injury in membranous nephropathy
    Masaomi Nangaku
    Division of Nephrology and Endocrinology, University of Tokyo School of Medicine, Tokyo, Japan
    J Am Soc Nephrol 16:1195-204. 2005

Detail Information

Publications42

  1. doi request reprint Basic and translational concepts of immune-mediated glomerular diseases
    William G Couser
    Division of Nephrology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
    J Am Soc Nephrol 23:381-99. 2012
    ..Advances in understanding the immunopathogenesis of each of these entities offer many opportunities for future therapeutic interventions...
  2. ncbi request reprint Chronic kidney disease the promise and the perils
    William G Couser
    University of Washington, Seattle, Washington, USA
    J Am Soc Nephrol 18:2803-5. 2007
  3. ncbi request reprint Recurrent glomerulonephritis in the renal allograft: an update of selected areas
    William Couser
    Division of Nephrology, Department of Medicine, University of Washington, Seattle, WA, USA
    Exp Clin Transplant 3:283-8. 2005
    ..Proper donor selection, early diagnosis in high-risk patients, and appropriate management can prolong graft survival and improve long-term outcomes...
  4. ncbi request reprint Cellular and molecular biology of membranous nephropathy
    William G Couser
    Division of Nephrology, University of Washington, Seattle, Washington, USA
    J Nephrol 19:699-705. 2006
    ..Expanded understanding of the molecular pathophysiology of MN has important implications for monitoring disease activity, predicting disease course and designing new approaches to therapy for this common glomerular disease...
  5. ncbi request reprint Membranous nephropathy: a long road but well traveled
    William G Couser
    Division of Nephrology, University of Washington, Seattle, USA
    J Am Soc Nephrol 16:1184-7. 2005
  6. doi request reprint The contribution of chronic kidney disease to the global burden of major noncommunicable diseases
    William G Couser
    International Society of Nephrology Global Outreach Program, Brussels, Belgium
    Kidney Int 80:1258-70. 2011
    ..Prevention of CKD should be considered in planning and implementation of national NCD policy in the developed and developing world...
  7. doi request reprint The message for World Kidney Day 2009: hypertension and kidney disease: a marriage that should be prevented
    George L Bakris
    Hypertensive Diseases Unit, Department of Medicine, Pritzker School of Medicine, University of Chicago, Chicago, IL, USA
    J Clin Hypertens (Greenwich) 11:144-7. 2009
    ..Therefore, treatment of hypertension has become the most important intervention in the management of all forms of CKD. For this reason, World Kidney Day on March 12, 2009 will emphasize the role of hypertension...
  8. doi request reprint The message for World Kidney Day 2009: hypertension and kidney disease--a marriage that should be prevented
    George L Bakris
    Department of Medicine, Hypertensive Diseases Unit, University of Chicago, Pritzker School of Medicine, Chicago, Illinois, USA
    J Hypertens 27:666-9. 2009
    ..Therefore, treatment of hypertension has become the most important intervention in the management of all forms of CKD. For this reason, the forthcoming World Kidney Day on 12 March 2009 will emphasize the role of hypertension...
  9. doi request reprint Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010
    Christopher J L Murray
    Institute for Health Metrics and Evaluation, Seattle 98121, WA, USA
    Lancet 380:2197-223. 2012
    ..We aimed to calculate disease burden worldwide and for 21 regions for 1990, 2005, and 2010 with methods to enable meaningful comparisons over time...
  10. ncbi request reprint Cellular response to injury in membranous nephropathy
    Masaomi Nangaku
    Division of Nephrology and Endocrinology, University of Tokyo School of Medicine, Tokyo, Japan
    J Am Soc Nephrol 16:1195-204. 2005
    ..Improved understanding of the role of complement in the pathogenesis of MN and of the cellular response to C5b-9 attack creates several new opportunities for therapeutic intervention that may benefit patients with MN in the future...
  11. ncbi request reprint Mechanisms of immune-deposit formation and the mediation of immune renal injury
    Masaomi Nangaku
    Division of Nephrology and Endocrinology, University of Tokyo School of Medicine, 7 3 1 Bunkyo ku, Tokyo, 113 8655, Japan
    Clin Exp Nephrol 9:183-91. 2005
    ..Particularly promising future therapeutic approaches include selective immunosuppression and interference in complement activation and C5b-9-mediated cell injury...
  12. ncbi request reprint C5b-9 regulates peritubular myofibroblast accumulation in experimental focal segmental glomerulosclerosis
    Gopala K Rangan
    Division of Nephrology, University of Washington Medical Center, Seattle, Washington, USA
    Kidney Int 66:1838-48. 2004
    ..Here, we hypothesized that C5b-9 formation regulates renal myofibroblast accumulation in Adriamycin nephropathy...
  13. ncbi request reprint Localization of SPARC in developing, mature, and chronically injured human allograft kidneys
    Charles E Alpers
    Department of Pathology, University of Washington School of Medicine, Seattle Washington, USA
    Kidney Int 62:2073-86. 2002
    ..This study describes the expression of SPARC during human renal development, in normal kidneys and during renal allograft rejection...
  14. ncbi request reprint Chronic kidney disease - how many have it?
    William G Couser
    J Am Soc Nephrol 13:2810. 2002
  15. ncbi request reprint C6 mediates chronic progression of tubulointerstitial damage in rats with remnant kidneys
    Masaomi Nangaku
    Division of Nephrology and Endocrinology, University of Tokyo School of Medicine, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    J Am Soc Nephrol 13:928-36. 2002
    ..Treatment to reduce C5b-9 attack in tubular cells may slow progression and facilitate recovery...
  16. ncbi request reprint World Kidney Day: an idea whose time has come
    Allan J Collins
    Kidney Int 69:781-2. 2006
  17. ncbi request reprint World Kidney Day: an idea whose time has come
    Allan J Collins
    Natl Med J India 19:55-7. 2006
  18. ncbi request reprint A call to action on World Kidney Day, 8 March 2007
    William G Couser
    Kidney Int 71:369-70. 2007
  19. doi request reprint The third World Kidney Day: looking back and thinking forward
    Sudhir V Shah
    University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, Arkansas, USA
    Nephrol Dial Transplant 23:471-3. 2008
  20. ncbi request reprint ISN and the 'new nephrology'
    William G Couser
    Nat Clin Pract Nephrol 2:541. 2006
  21. doi request reprint The third World Kidney Day: looking back and thinking forward
    Sudhir V Shah
    Transplantation 85:495-8. 2008
  22. doi request reprint The third World Kidney Day: looking back and thinking forward
    Sudhir V Shah
    Department of Internal Medicine, Division of Nephrology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Nephron Clin Pract 108:c241-4. 2008
  23. ncbi request reprint A call to action on World Kidney Day, 8 March 2007
    William G Couser
    Nephrology (Carlton) 12:1-2. 2007
  24. doi request reprint The Third World Kidney Day: looking back and thinking forward
    Sudhir V Shah
    Nephrology (Carlton) 13:51-2. 2008
  25. ncbi request reprint World Kidney Day: an idea whose time has come
    Allan J Collins
    Nephrology (Carlton) 11:1-2. 2006
  26. ncbi request reprint World Kidney Day: an idea whose time has come
    Allan J Collins
    Am J Kidney Dis 47:375-7. 2006
  27. ncbi request reprint An introduction to frontiers in nephrology
    Allison A Eddy
    Deputy Editor, Journal of the American Society of Nephrology
    J Am Soc Nephrol 13:2185. 2002
  28. ncbi request reprint Mechanical stress reduces podocyte proliferation in vitro
    Arndt T Petermann
    Division of Nephrology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Kidney Int 61:40-50. 2002
    ..However, the effects of stretch on podocyte growth and the mechanisms that underlie this have not been elucidated...
  29. ncbi request reprint Mitotic cell cycle proteins increase in podocytes despite lack of proliferation
    Arndt T Petermann
    Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Kidney Int 63:113-22. 2003
    ..Podocyte proliferation is an uncommon response to glomerular injury and its lack may underlie the development of glomerulosclerosis. However, whether podocytes have the capacity to enter and finish mitosis and cytokinesis is not known...
  30. ncbi request reprint Complement inhibitors and glomerulonephritis: are we there yet?
    William G Couser
    J Am Soc Nephrol 14:815-8. 2003
  31. pmc DNA damage is a novel response to sublytic complement C5b-9-induced injury in podocytes
    Jeffrey W Pippin
    Department of Medicine, Division of Nephrology, University of Washington, Seattle, Washington 98195, USA
    J Clin Invest 111:877-85. 2003
    ..These results show that sublytic C5b-9 induces DNA damage in vitro and in vivo and may explain why podocyte proliferation is limited following immune-mediated injury...
  32. ncbi request reprint Amelioration of diabetic nephropathy in SPARC-null mice
    Sekiko Taneda
    Department of Pathology, Division of Nephrology, University of Washington, Seattle Washington 98195, USA
    J Am Soc Nephrol 14:968-80. 2003
    ..These observations suggest that SPARC contributes to glomerulosclerosis and tubulointerstitial damage in response to hyperglycemia through increasing TGF-beta 1 expression in this model of chronic DN...
  33. ncbi request reprint Chronic progression of tubulointerstitial damage in proteinuric renal disease is mediated by complement activation: a therapeutic role for complement inhibitors?
    Stephen I Hong Hsu
    Institute of Prevention and Research, National Kidney Foundation of Singapore
    J Am Soc Nephrol 14:S186-91. 2003
    ..This paradigm has important implications for the potential therapeutic role of complement inhibitors that are currently being developed...
  34. ncbi request reprint Therapy of membranous nephropathy associated with malignancy and secondary causes
    J Ashley Jefferson
    University of Washington, Seattle, USA
    Semin Nephrol 23:400-5. 2003
    ..In this article we describe the clinical approach to patients with MN associated with malignancy and other common secondary causes. Treatment of secondary MN generally targets the primary disease rather than the renal lesion...
  35. ncbi request reprint Activation of a local tissue angiotensin system in podocytes by mechanical strain
    Raghu V Durvasula
    Department of Medicine, Division of Nephrology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Kidney Int 65:30-9. 2004
    ..Accordingly, we have tested the hypothesis that mechanical strain up-regulates local angiotensin II in podocytes, thereby resulting in a progressive reduction in podocyte number...
  36. pmc Differential expression of d-type cyclins in podocytes in vitro and in vivo
    Arndt Petermann
    Universitätsklinikum RWTH Aachen, Aachen, Germany
    Am J Pathol 164:1417-24. 2004
    ..Cyclin D1 is not necessary for the terminal differentiation of podocytes, and expression coincides with cell-cycle entry. In contrast, cyclin D3 expression coincides with podocyte differentiation and quiescence...
  37. ncbi request reprint Mechanical stretch induces podocyte hypertrophy in vitro
    Arndt T Petermann
    Department of Medicine, Division of Nephrology, University of Washington School of Medicine, Seattle, Washington 98195, USA
    Kidney Int 67:157-66. 2005
    ..Increased intraglomerular pressure causes stress-tension, or stretch, on resident glomerular cells. However, the effects of stretch on podocyte growth, and the mechanisms that underlie this, have not been elucidated...
  38. ncbi request reprint Uniform clinical trial registration policy for journals of kidney diseases, dialysis, and transplantation
    William G Couser
    J Am Soc Nephrol 16:837. 2005
  39. ncbi request reprint A uniform clinical trial registration policy for journals of kidney diseases, dialysis and transplantation
    William G Couser
    Journal of the American Society of Nephrology
    Am J Transplant 5:643. 2005
  40. ncbi request reprint C5b-9 does not mediate chronic tubulointerstitial disease in the absence of proteinuria
    Gopala K Rangan
    Division of Nephrology, University of Washington Medical Center, Seattle, Washington, USA
    Kidney Int 67:492-503. 2005
    ..Here, we examined whether C5b-9 has a pathogenic role in tubulointerstitial disease in the absence of proteinuria...
  41. ncbi request reprint World Kidney Day: an idea whose time has come
    Allan J Collins
    J Am Soc Nephrol 17:600-1. 2006
  42. ncbi request reprint Effects of cyclosporine in osteopontin null mice
    Marilda Mazzali
    Division of Nephrology, Department of Pathology, University of Washington, Seattle, Washington, USA
    Kidney Int 62:78-85. 2002
    ..This study tested the hypothesis that the absence of OPN would ameliorate CsA nephropathy...