J R Couchman

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi Syndecan-4 and integrins: combinatorial signaling in cell adhesion
    J R Couchman
    Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, University Boulevard, Birmingham, AL 35294 0019, USA
    J Cell Sci 112:3415-20. 1999
  2. ncbi Control of morphology, cytoskeleton and migration by syndecan-4
    R L Longley
    Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Cell Sci 112:3421-31. 1999
  3. ncbi Syndecan-4 binding to the high affinity heparin-binding domain of fibronectin drives focal adhesion formation in fibroblasts
    A Woods
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, 35294 0019, USA
    Arch Biochem Biophys 374:66-72. 2000
  4. ncbi Localization of glycosaminoglycan substitution sites on domain V of mouse perlecan
    P Tapanadechopone
    Department of Cell Biology, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, 35294 0019, USA
    Biochem Biophys Res Commun 265:680-90. 1999
  5. ncbi Syndecans and cell adhesion
    J R Couchman
    Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 35294, USA
    Int Rev Cytol 207:113-50. 2001
  6. ncbi Serine phosphorylation of syndecan-2 proteoglycan cytoplasmic domain
    E S Oh
    Department of Cell Biology, and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 35294, USA
    Arch Biochem Biophys 344:67-74. 1997
  7. ncbi Syndecan-4 and focal adhesion function
    A Woods
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0019, USA
    Curr Opin Cell Biol 13:578-83. 2001
  8. ncbi Basement membrane and interstitial proteoglycans produced by MDCK cells correspond to those expressed in the kidney cortex
    A C Erickson
    Department of Cell Biology and Cell Adhesion and Matrix Biology Research Center, University of Alabama at Birmingham, 1670 University Blvd, VH 201C, Birmingham, AL 35294-0019, USA
    Matrix Biol 19:769-78. 2001
  9. ncbi Proteoglycan isolation and analysis
    A Woods
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Protoc Cell Biol . 2001
  10. ncbi Epidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity
    P Tapanadechopone
    Department of Cell Biology, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 201C Volker Hall, 1670 University Blvd, Birmingham, Alabama 35294-0019, USA
    Biochem J 355:517-27. 2001

Collaborators

Detail Information

Publications11

  1. ncbi Syndecan-4 and integrins: combinatorial signaling in cell adhesion
    J R Couchman
    Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, University Boulevard, Birmingham, AL 35294 0019, USA
    J Cell Sci 112:3415-20. 1999
    ....
  2. ncbi Control of morphology, cytoskeleton and migration by syndecan-4
    R L Longley
    Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, USA
    J Cell Sci 112:3421-31. 1999
    ..The data suggest that syndecan-4 is a regulator of focal adhesion and stress fiber formation, and influences both morphology and migration...
  3. ncbi Syndecan-4 binding to the high affinity heparin-binding domain of fibronectin drives focal adhesion formation in fibroblasts
    A Woods
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Alabama, 35294 0019, USA
    Arch Biochem Biophys 374:66-72. 2000
    ..We now report that the glycosaminoglycan chains of syndecan-4 bind recombinant HepII and it is incorporated into forming focal adhesions...
  4. ncbi Localization of glycosaminoglycan substitution sites on domain V of mouse perlecan
    P Tapanadechopone
    Department of Cell Biology, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, Birmingham, Alabama, 35294 0019, USA
    Biochem Biophys Res Commun 265:680-90. 1999
    ..When this sequence was absent, chondroitin/dermatan sulfate substitution was deleted, and the likely site for this galactosaminoglycan substitution was ser-gly-ala-gly (serine residue 3250) on domain V...
  5. ncbi Syndecans and cell adhesion
    J R Couchman
    Department of Cell Biology and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 35294, USA
    Int Rev Cytol 207:113-50. 2001
    ..This review will describe this family of proteoglycans in terms of their structures and functions and their signaling in conjunction with integrins, and indicate areas for future research...
  6. ncbi Serine phosphorylation of syndecan-2 proteoglycan cytoplasmic domain
    E S Oh
    Department of Cell Biology, and Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 35294, USA
    Arch Biochem Biophys 344:67-74. 1997
    ..5 mol/mol phosphorylation. Concentration-dependent dimerization was not altered by phosphorylation. Phosphorylation is, therefore, dependent on the conformation of syndecan-2 cytoplasmic domain, but does not affect its oligomeric status...
  7. ncbi Syndecan-4 and focal adhesion function
    A Woods
    Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294 0019, USA
    Curr Opin Cell Biol 13:578-83. 2001
    ..This is consistent with recent in vitro data indicating a need for signaling via syndecan-4 for focal adhesion formation, and reports that overexpression of proteins that bind syndecan-4 can modify cell adhesion and migration...
  8. ncbi Basement membrane and interstitial proteoglycans produced by MDCK cells correspond to those expressed in the kidney cortex
    A C Erickson
    Department of Cell Biology and Cell Adhesion and Matrix Biology Research Center, University of Alabama at Birmingham, 1670 University Blvd, VH 201C, Birmingham, AL 35294-0019, USA
    Matrix Biol 19:769-78. 2001
    ..Various CSPG core proteins are made by MDCK cells and have been identified as biglycan, bamacan, and versican (PG-M). These PGs are also associated with mammalian kidney tubules in vivo...
  9. ncbi Proteoglycan isolation and analysis
    A Woods
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Curr Protoc Cell Biol . 2001
    ..This unit describes detailed methods for purification of matrix, cell surface, and cytoskeleton-linked proteoglycans. Methods for analysis of glycoaminoglycan size and type and of core protein species are described...
  10. ncbi Epidermal transformation leads to increased perlecan synthesis with heparin-binding-growth-factor affinity
    P Tapanadechopone
    Department of Cell Biology, Cell Adhesion and Matrix Research Center, University of Alabama at Birmingham, 201C Volker Hall, 1670 University Blvd, Birmingham, Alabama 35294-0019, USA
    Biochem J 355:517-27. 2001
    ..Therefore abundant tumour-derived perlecan may support the angiogenic responses seen in vivo and be a key player in tumorigenesis...
  11. ncbi cDNA cloning of the basement membrane chondroitin sulfate proteoglycan core protein, bamacan: a five domain structure including coiled-coil motifs
    R R Wu
    Department of Cell Biology, University of Alabama at Birmingham, 35294 0019, USA
    J Cell Biol 136:433-44. 1997
    ..The unusual structure of this proteoglycan is indicative of specific functional roles in basement membrane physiology, commensurate with its distinct expression in development and changes in disease models...