PEGGY COTTERSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Phosphorelay control of virulence gene expression in BordetellaPeggy A Cotter
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106-9610, USA
Trends Microbiol 11:367-73. 2003- c-di-GMP-mediated regulation of virulence and biofilm formationPeggy A Cotter
Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
Curr Opin Microbiol 10:17-23. 2007.... 
Type VI secretion: not just for pathogenesis anymoreAndrea J Jani
Biomolecular Science and Engineering Program, University of California, Santa Barbara, Santa Barbara, CA 93106, USA
Cell Host Microbe 8:2-6. 2010....- Characterization of the filamentous hemagglutinin-like protein FhaS in Bordetella bronchisepticaSteven M Julio
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
Infect Immun 73:4960-71. 2005..parapertussis(hu) most likely acquired its fhaS allele from B. pertussis horizontally, suggesting fhaS may contribute to host-species specificity... - Natural-host animal models indicate functional interchangeability between the filamentous haemagglutinins of Bordetella pertussis and Bordetella bronchiseptica and reveal a role for the mature C-terminal domain, but not the RGD motif, during infectionSteven M Julio
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
Mol Microbiol 71:1574-90. 2009..We could not, however, detect a role for the RGD in any of these processes... - Autoregulation is essential for precise temporal and steady-state regulation by the Bordetella BvgAS phosphorelayCorinne L Williams
Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106 9610, USA
J Bacteriol 189:1974-82. 2007..In addition, considered in relation to BvgA and BvgS activities demonstrated in vitro, our results provide insight into how BvgA and BvgS function mechanistically... - Topology and maturation of filamentous haemagglutinin suggest a new model for two-partner secretionJoseph Mazar
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106-9610, USA
Mol Microbiol 62:641-54. 2006..This model provides an explanation for the energetics of export of globular protein domains across membranes in the absence of ATP and it suggests a new mechanism for the control of protein folding... - Role of BvgA phosphorylation and DNA binding affinity in control of Bvg-mediated phenotypic phase transition in Bordetella pertussisAllison M Jones
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93109-9610, USA
Mol Microbiol 58:700-13. 2005.... - BvgA functions as both an activator and a repressor to control Bvg phase expression of bipA in Bordetella pertussisCorinne L Williams
Department of Molecular, Cellular and Developmental Biology, University of California, Santa Barbara, CA 93106-9610, USA
Mol Microbiol 56:175-88. 2005.... - Bordetella filamentous hemagglutinin plays a critical role in immunomodulation, suggesting a mechanism for host specificityCarol S Inatsuka
Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, CA 93106-9610, USA
Proc Natl Acad Sci U S A 102:18578-83. 2005..These results indicate a critical role for FHA in B. bronchiseptica-mediated immunomodulation, and they suggest a role for FHA in host specificity... - Serendipitous discovery of an immunoglobulin-binding autotransporter in Bordetella speciesCorinne L Williams
Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA 93106 9610, USA
Infect Immun 76:2966-77. 2008..bronchiseptica. Taken together, our data suggest that BatB played an important role in the evolution of virulence and host specificity among the mammalian-adapted bordetellae... - Pertactin is required for Bordetella species to resist neutrophil-mediated clearanceCarol S Inatsuka
Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, California 93106 9610, USA
Infect Immun 78:2901-9. 2010.... - Reverse transcriptase-mediated tropism switching in Bordetella bacteriophageMinghsun Liu
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA
Science 295:2091-4. 2002..This cassette-based mechanism is capable of providing a vast repertoire of potential ligand-receptor interactions... - New insight into the molecular mechanisms of two-partner secretionJoseph Mazar
Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106 9610, USA
Trends Microbiol 15:508-15. 2007..Evidence for secretion-dependent folding of mature exoproteins has also been obtained. Together, these findings provide a deeper understanding of the molecular mechanisms underlying these simple but elegant secretion systems... - Comparative phenotypic analysis of the Bordetella parapertussis isolate chosen for genomic sequencingUlrich Heininger
Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles School of Medicine, University of California-Los Angeles, Los Angeles, California 90095-1747, USA
Infect Immun 70:3777-84. 2002..pertussis (by lack of motility and cytotoxicity to a macrophage-like cell line). These results begin to provide phenotypes that can be related to genetic differences identified in the genomic sequences of bordetellae... - Evaluation of the role of the Bvg intermediate phase in Bordetella pertussis during experimental respiratory infectionNuria Vergara-Irigaray
, Universidad de Navarra, Apartado 177, 31080 Pamplona, Spain
Infect Immun 73:748-60. 2005..Finally, even though B. pertussis expresses in vitro the Bvg(i) phase at the human nasal temperature, anti-BipA antibodies were undetectable in a large collection of sera from pertussis patients... - Microbial pathogenesis: mechanisms of infectious diseaseVern B Carruthers
Department of Microbiology and Immunology, University of Michigan, Ann Arbor, MI 48109, USA
Cell Host Microbe 2:214-9. 2007..Here, we review the presented research that highlights this theme, including studies of both short-term and long-term interactions between microbes and their hosts...
Research Grants
- GENETIC ANALYSIS OF BORDETELLA PAHTOGENESISPEGGY COTTER; Fiscal Year: 2003..The Principal Investigator plans to investigate a recently discovered Bvg intermediate phase gene and test the hypothesis that this phase is essential for transmission. ..
- Genetic Analysis of Bordetella PathogenesisPEGGY COTTER; Fiscal Year: 2007....
- Genetic Analysis of Bordetella PathogenesisPEGGY COTTER; Fiscal Year: 2009....