Scott J Cotler

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. ncbi request reprint Characteristics of hepatitis C in renal transplant candidates
    Scott J Cotler
    Department of Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, U S A
    J Clin Gastroenterol 35:191-5. 2002
  2. doi request reprint Characterizing hepatitis B stigma in Chinese immigrants
    S J Cotler
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    J Viral Hepat 19:147-52. 2012
  3. doi request reprint The prevalence and clinical correlates of elevated ALT levels in an urban Chinatown community
    S J Cotler
    Department of Medicine, University of Illinois, Chicago, IL, USA
    J Viral Hepat 17:148-52. 2010
  4. ncbi request reprint Measurement of liver fat content using selective saturation at 3.0 T
    Scott J Cotler
    Section of Hepatology, Department of Pathology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Magn Reson Imaging 25:743-8. 2007
  5. ncbi request reprint Hepatitis B seroprevalence and disease characteristics in an urban Chinatown community
    Scott J Cotler
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA
    Clin Gastroenterol Hepatol 7:776-80. 2009
  6. ncbi request reprint Immunohistochemical expression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease
    Scott J Cotler
    Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA
    Dig Dis Sci 53:844-9. 2008
  7. ncbi request reprint Diabetes and hepatic oxidative damage are associated with hepatitis C progression after liver transplantation
    Scott J Cotler
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    Transplantation 84:587-91. 2007
  8. ncbi request reprint Hepatic decompensation after gastric bypass surgery for severe obesity
    Scott J Cotler
    Section of Hepatology, The University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Dig Dis Sci 49:1563-8. 2004
  9. ncbi request reprint Prevalence and significance of autoantibodies in patients with non-alcoholic steatohepatitis
    Scott J Cotler
    University of Illinois at Chicago, Chicago, Illinois, USA
    J Clin Gastroenterol 38:801-4. 2004
  10. pmc Pharmacodynamics of PEG-IFN-alpha-2a in HIV/HCV co-infected patients: implications for treatment outcomes
    Harel Dahari
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Hepatol 53:460-7. 2010

Detail Information

Publications50

  1. ncbi request reprint Characteristics of hepatitis C in renal transplant candidates
    Scott J Cotler
    Department of Medicine, Rush Presbyterian St Luke s Medical Center, Chicago, Illinois 60612, U S A
    J Clin Gastroenterol 35:191-5. 2002
    ..To characterize hepatitis C in renal transplant candidates and to compare hepatitis C-related liver disease between patients with end-stage renal disease (ESRD) and well-matched control subjects without renal disease...
  2. doi request reprint Characterizing hepatitis B stigma in Chinese immigrants
    S J Cotler
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    J Viral Hepat 19:147-52. 2012
    ..The relationship identified between familiarity and knowledge regarding HBV with lower stigma scores provides the basis for the development of interventions to reduce HBV stigma...
  3. doi request reprint The prevalence and clinical correlates of elevated ALT levels in an urban Chinatown community
    S J Cotler
    Department of Medicine, University of Illinois, Chicago, IL, USA
    J Viral Hepat 17:148-52. 2010
    ..Liver biopsy should be performed in selected patients with HBV to distinguish the cause of ALT elevation before initiating antiviral therapy...
  4. ncbi request reprint Measurement of liver fat content using selective saturation at 3.0 T
    Scott J Cotler
    Section of Hepatology, Department of Pathology, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Magn Reson Imaging 25:743-8. 2007
    ..To validate an MRI technique for measuring liver fat content by calibrating MRI readings with liver phantoms and comparing MRI measurements in human subjects with estimates of liver fat content on liver biopsy specimens...
  5. ncbi request reprint Hepatitis B seroprevalence and disease characteristics in an urban Chinatown community
    Scott J Cotler
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA
    Clin Gastroenterol Hepatol 7:776-80. 2009
    ..The aim of this study was to evaluate the HBsAg seroprevalence and to characterize hepatitis B in persons who presented to an urban Chinatown internal medicine practice...
  6. ncbi request reprint Immunohistochemical expression of components of the Akt-mTORC1 pathway is associated with hepatocellular carcinoma in patients with chronic liver disease
    Scott J Cotler
    Department of Medicine, The University of Illinois at Chicago, Chicago, IL 60612, USA
    Dig Dis Sci 53:844-9. 2008
    ..Activation of the Akt-mTORC1 signaling pathway was evaluated in premalignant and hepatocellular carcinoma (HCC) lesions by assessing the expression of pS6, an Akt effector, and PTEN, an Akt suppressor...
  7. ncbi request reprint Diabetes and hepatic oxidative damage are associated with hepatitis C progression after liver transplantation
    Scott J Cotler
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    Transplantation 84:587-91. 2007
    ..The aim of this study was to evaluate the relationship among PTDM, oxidative damage in liver biopsy specimens, and fibrosis progression posttransplant...
  8. ncbi request reprint Hepatic decompensation after gastric bypass surgery for severe obesity
    Scott J Cotler
    Section of Hepatology, The University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Dig Dis Sci 49:1563-8. 2004
  9. ncbi request reprint Prevalence and significance of autoantibodies in patients with non-alcoholic steatohepatitis
    Scott J Cotler
    University of Illinois at Chicago, Chicago, Illinois, USA
    J Clin Gastroenterol 38:801-4. 2004
    ..The aim of this study is to evaluate the prevalence and the clinical and histologic correlates of autoantibodies in patients with nonalcoholic steatohepatitis (NASH)...
  10. pmc Pharmacodynamics of PEG-IFN-alpha-2a in HIV/HCV co-infected patients: implications for treatment outcomes
    Harel Dahari
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Hepatol 53:460-7. 2010
    ..We sought to estimate the pharmacokinetics and pharmacodynamics of PEG-IFN and determine whether these parameters predict treatment outcome...
  11. doi request reprint Ethnicity and body mass index are associated with hepatitis C presentation and progression
    Eric R Kallwitz
    Department of Medicine, University of Illinois, Chicago, Illinois, USA
    Clin Gastroenterol Hepatol 8:72-8. 2010
    ..We evaluated the association between elements of the metabolic syndrome and ethnicity in the histologic progression of HCV in a large, diverse cohort...
  12. pmc A mathematical model of hepatitis C virus dynamics in patients with high baseline viral loads or advanced liver disease
    Harel Dahari
    Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA
    Gastroenterology 136:1402-9. 2009
    ....
  13. ncbi request reprint Imaging surveillance and multidisciplinary review improves curative therapy access and survival in HCC patients
    Ron C Gaba
    University of Illinois Hospital and Health Sciences System, Department of Radiology Chicago, IL, USA
    Ann Hepatol 12:766-73. 2013
    ..Geographic disparities in donor organ availability may reduce this benefit. This study evaluated the impact of HCC surveillance on use of curative therapies and survival in a region with long transplant waiting times...
  14. ncbi request reprint Viral kinetics in the treatment of chronic hepatitis C
    Jennifer E Layden-Almer
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612 7323, USA
    J Viral Hepat 13:499-504. 2006
    ..Once-weekly dosing with peg-INF-alpha2a, which has a longer half-life than other forms of INF, plus daily dosing with ribavirin, has been shown to be effective in reducing viral load...
  15. ncbi request reprint Prognostic capability of different liver disease scoring systems for prediction of early mortality after transjugular intrahepatic portosystemic shunt creation
    Ron C Gaba
    Department of Radiology, University of Illinois Medical Center at Chicago, 1740 West Taylor Street, MC 931, Chicago, IL 60612, USA
    J Vasc Interv Radiol 24:411-20, 420.e1-4; quiz 421. 2013
    ..To compare the performance of various liver disease scoring systems in predicting early mortality after transjugular intrahepatic portosystemic shunt (TIPS) creation...
  16. doi request reprint The histologic spectrum of liver disease in African-American, non-Hispanic white, and Hispanic obesity surgery patients
    Eric R Kallwitz
    Department of Medicine, University of Illinois at Chicago, 840 S Wood Street, Chicago, IL 60612, USA
    Am J Gastroenterol 104:64-9. 2009
    ..The aim of this study was to evaluate ethnic differences in the prevalence of NAFLD and non-alcoholic steatohepatitis (NASH) and to compare the severity of histologic features of NASH in obesity surgery patients...
  17. doi request reprint Does nonalcoholic fatty liver disease predispose patients to hepatocellular carcinoma in the absence of cirrhosis?
    Grace Guzman
    Department of Pathology, University of Illinois at Chicago, Chicago, IL 60614, USA
    Arch Pathol Lab Med 132:1761-6. 2008
    ..Diabetes and the metabolic syndrome are also associated with HCC. However, it is not clear whether NAFLD predisposes patients to HCC in the absence of cirrhosis...
  18. pmc Modelling hepatitis C virus kinetics: the relationship between the infected cell loss rate and the final slope of viral decay
    Harel Dahari
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    Antivir Ther 14:459-64. 2009
    ..In standard models, lambda is approximately epsilondelta when the viral clearance rate c>>delta, as has been previously estimated...
  19. doi request reprint Ethnicity and nonalcoholic fatty liver disease in an obesity clinic: the impact of triglycerides
    Eric R Kallwitz
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Dig Dis Sci 53:1358-63. 2008
    ..In conclusion, in an obesity clinic population, elevated aminotransferase levels and hypertriglyceridemia were most common in Hispanics and least common in African Americans...
  20. doi request reprint Quantitative morphometric analysis of hepatocellular carcinoma: development of a programmed algorithm and preliminary application
    Felix Y Yap
    Department of Radiology, University of Illinois at Chicago, Chicago, Illinois, USA
    Diagn Interv Radiol 19:97-105. 2013
    ..We designed a computer algorithm to analyze shape features of hepatocellular carcinoma (HCC) and tested feasibility of morphologic analysis...
  21. ncbi request reprint Alpha-methylacyl-CoA racemase (AMACR/P504S) can distinguish hepatocellular carcinoma and dysplastic hepatocytes from benign nondysplastic hepatocytes
    Grace Guzman
    Department of Pathology, University of Illinois at Chicago Medical Center UICMC, College of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Appl Immunohistochem Mol Morphol 14:411-6. 2006
    ..Prospective studies are needed to determine whether staining for AMACR can distinguish HCC or dysplasia in cytologic and small histologic specimens...
  22. doi request reprint Barriers to treatment of hepatitis B in an urban Chinatown community
    Miguel Malespin
    Department of Medicine, Section of Hepatology, University of Illinois, Chicago, IL 60612, USA
    J Clin Gastroenterol 46:e66-70. 2012
    ..To evaluate the net effect of a concerted effort to treat hepatitis B virus (HBV) in a Chinese immigrant population, including barriers to initiating and continuing therapy and antiviral efficacy...
  23. doi request reprint TIPS for treatment of variceal hemorrhage: clinical outcomes in 128 patients at a single institution over a 12-year period
    Ron C Gaba
    Department of Radiology Interventional Radiology Section, University of Illinois Medical Center at Chicago, 1740 W Taylor St, MC 931, Chicago, IL 60612, USA
    J Vasc Interv Radiol 23:227-35. 2012
    ..To assess clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) treatment of variceal hemorrhage...
  24. ncbi request reprint p53, Ki-67, and serum alpha feto-protein as predictors of hepatocellular carcinoma recurrence in liver transplant patients
    Grace Guzman
    Department of Pathology, University of Illinois at Chicago Medical Center UICMC, College of Medicine, University of Illinois at Chicago, IL 60612, USA
    Mod Pathol 18:1498-503. 2005
    ..Identification of patients at risk for early post-transplant recurrence could be used to guide surveillance and adjuvant treatment strategies...
  25. pmc A pilot study of vasculogenic mimicry immunohistochemical expression in hepatocellular carcinoma
    Grace Guzman
    Department of Pathology, University of Illinois Medical Center at Chicago, 840 S Wood St, Room 130 CSN MC 847, Chicago, IL 60612 7335, USA
    Arch Pathol Lab Med 131:1776-81. 2007
    ..The "de novo" formation of fluid-conducting patterns by tumor cells, termed vasculogenic mimicry (VM), is associated with increased mortality in many different solid tumors...
  26. pmc Impact of donor and recipient race on survival after hepatitis C-related liver transplantation
    Jennifer E Layden
    Department of Medicine, University of Illinois at Chicago, Chicago, IL 60612, USA
    Transplantation 93:444-9. 2012
    ..The purpose of this study was to examine the impact of donor and recipient race on recipient and graft survival after HCV-related LT using the United Network for Organ Sharing database...
  27. ncbi request reprint Laboratory diagnosis and nonoperative management of biliary complications in living donor liver transplant patients
    Mukund Venu
    Digestive Disease and Nutrition, Hepatology, and Transplantation, University of Illinois Medical Center at Chicago, Chicago, IL 60612, USA
    J Clin Gastroenterol 41:501-6. 2007
    ..Information regarding biochemical abnormalities helpful for the diagnosis and the nonoperative management of such complications are limited...
  28. ncbi request reprint Hepatitis C treatment eligibility in an urban population with and without HIV coinfection
    Oluwatoyin M Adeyemi
    Department of Medicine, Cook County Hospital, Chicago, Illinois 60612, USA
    AIDS Patient Care STDS 18:239-45. 2004
    ..These findings highlight the need to develop interventions to improve adherence and to manage substance abuse and other comorbidities in order to maximize the impact of interferon and ribavirin therapy on urban patients with hepatitis C...
  29. ncbi request reprint Adult living donor liver transplantation: perspectives from 100 liver transplant surgeons
    Scott J Cotler
    Rush Presbyterian St Luke s Medical Center, Chicago, IL, USA
    Liver Transpl 9:637-44. 2003
    ..In conclusion, the findings of this survey indicate that transplant surgeons are working to balance their moral imperative to provide life-saving therapy for transplantation candidates with the risks posed to living donors...
  30. pmc Characterization of antigenic variants of hepatitis C virus in immune evasion
    Jane H Wang
    Section of Hepatology, Department of Medicine, University of Illinois at Chicago, Illinois, USA
    Virol J 8:377. 2011
    ..Antigenic variation is an effective way by which viruses evade host immune defense leading to viral persistence. Little is known about the inhibitory mechanisms of viral variants on CD4 T cell functions...
  31. pmc Liver Injury with Features Mimicking Autoimmune Hepatitis following the Use of Black Cohosh
    Grace Guzman
    Department of Pathology, University of Illinois, Chicago, IL 60612, USA
    Case Report Med 2009:918156. 2009
    ..Liver injury following the use of black cohosh should be included in the list of differential diagnoses for chronic hepatitis with features mimicking autoimmune hepatitis...
  32. ncbi request reprint Liver enzymes and histology in obese patients with obstructive sleep apnea
    Eric R Kallwitz
    Department of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    J Clin Gastroenterol 41:918-21. 2007
    ..The aim of the current study was to compare biochemical and histologic findings in patients with NAFLD as a function of OSA status...
  33. ncbi request reprint Black cohosh (Actaea racemosa) for the mitigation of menopausal symptoms: recent developments in clinical safety and efficacy
    Gail B Mahady
    University of Illinois, Chicago, Department of Pharmacy Practice, PAHO WHO Collaborating Centre, College of Pharmacy, 833 South Wood Street, MC 886, Chicago, IL 60612, USA
    Womens Health (Lond Engl) 2:773-83. 2006
    ..At this time, it appears prudent to advise menopausal women with underlying liver disease, autoimmune diseases or those taking medications that may impact liver function not to use products containing black cohosh...
  34. pmc Chronic hepatitis C virus infection and increases in viral load in a prospective cohort of young, HIV-uninfected injection drug users
    Basmattee Boodram
    Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, 1603 West Taylor Street m c 923, Chicago, IL 60612, USA
    Drug Alcohol Depend 119:166-71. 2011
    ..This study aims to identify modifiable behavioral correlates both chronic HCV infection and increases in viral load over time among injection drug users (IDUs)...
  35. pmc Ethnic and geographical differences in HLA associations with the outcome of hepatitis C virus infection
    Jane H Wang
    Division of Hepatology, Department of Medicine, University of Illinois at Chicago, IL, USA
    Virol J 6:46. 2009
    ..The association of human leukocyte antigen (HLA) genes with the outcome of hepatitis C virus (HCV) infection may be modified by ethnic and geographical differences...
  36. ncbi request reprint Hepatitis C, iron status, and disease severity: relationship with HFE mutations
    Bruce Y Tung
    Department of Medicine, University of Washington School of Medicine, Seattle, USA
    Gastroenterology 124:318-26. 2003
    ..We sought to determine whether mutations in the hemochromatosis gene, HFE, are associated with iron overload and acceleration of disease progression in hepatitis C patients...
  37. ncbi request reprint A pilot study of the combination of cyclosporin A and interferon alfacon-1 for the treatment of hepatitis C in previous nonresponder patients
    Scott J Cotler
    Rush Presbyterian St Luke s Medical Center, Chicago, Illinois, USA
    J Clin Gastroenterol 36:352-5. 2003
    ..To evaluate the safety and efficacy of the combination of interferon and cyclosporine for the treatment of hepatitis C in previous nonresponder patients...
  38. pmc Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease
    Eric R Kallwitz
    Department of Medicine, University of Illinois, 840 S Wood Street, 7th Floor, MC 716, Chicago, IL 60612, USA
    World J Gastroenterol 14:22-8. 2008
    ..The aim of this review is to describe the data linking PPAR alpha and PPAR gamma to NAFLD/NASH and to discuss the use of PPAR ligands for the treatment of NASH...
  39. ncbi request reprint Management of hepatitis B in liver transplant patients
    Smruti R Mohanty
    Department of Medicine, Section of Gastroenterology and Nutrition, University of Chicago, Chicago, IL 60637, USA
    J Clin Gastroenterol 39:58-63. 2005
    ..In addition, there is interest in the use of therapeutic vaccination posttransplantation. In this report, we review strategies for managing HBV in the setting of liver transplantation and detail data regarding patient outcomes...
  40. ncbi request reprint Neutralizing antibodies in hepatitis C virus infection: a review of immunological and clinical characteristics
    Mitchell Kaplan
    Department of Internal Medicine, Rush Presbyterian St Luke s Medical Center, Rush University, Chicago, IL 60612, USA
    Gastroenterology 125:597-604. 2003
  41. ncbi request reprint Induction of IL-1Ra in resistant and responsive hepatitis C patients following treatment with IFN-con1
    Scott J Cotler
    Section of Hepatology and Department of Preventive Medicine, RUSH Presybterian St Luke s Medical Center, Chicago, IL 60612, USA
    J Interferon Cytokine Res 22:549-54. 2002
    ....
  42. ncbi request reprint Simple clinical variables predict liver histology in hepatitis C: prospective validation of a clinical prediction model
    Joseph Romagnuolo
    Digestive Disease Center, University of South Carolina, 96 Jonathon Lucas Street, PO Box 250 327, Charleston, SC 29425, USA
    Scand J Gastroenterol 40:1365-71. 2005
    ..Absence of predictors also predicted a lack of inflammation and fibrosis. Our aim was prospectively to validate this clinical prediction model using an independent multicenter sample...
  43. ncbi request reprint Liver transplantation for hepatocellular carcinoma: a survey of practices
    Erik J Van Kleek
    Department of Internal Medicine, Oregon Health and Sciences University, Portland, OR 97239, USA
    J Clin Gastroenterol 40:643-7. 2006
    ..To survey physician practices regarding liver transplantation for patients with hepatocellular carcinoma (HCC)...
  44. ncbi request reprint Prevalence of hepatic iron overload and association with hepatocellular cancer in end-stage liver disease: results from the National Hemochromatosis Transplant Registry
    Cynthia Ko
    Division of Gastroenterology, University of Washington Medical Center, Seattle, WA, USA
    Liver Int 27:1394-401. 2007
    ..This study examined the association between hepatic iron grade and hepatocellular carcinoma in patients with end-stage liver disease of diverse aetiologies...
  45. ncbi request reprint Survival after liver transplantation in patients with hepatic iron overload: the national hemochromatosis transplant registry
    Kris V Kowdley
    University of Washington, Seattle, 98195, USA
    Gastroenterology 129:494-503. 2005
    ..We examined the effect of HFE mutations on posttransplantation survival in patients with hepatic iron overload...
  46. doi request reprint How physicians describe outcomes to HCV therapy: prevalence and meaning of "cure" during provider-patient in-office discussions of HCV
    Heidi E Hamilton
    Georgetown University, Washington, DC, USA
    J Clin Gastroenterol 42:419-24. 2008
    ..Another study showed that 45% of patients did not understand projected response rates conveyed by providers, and patients with unfavorable projected treatment outcomes were more likely to lack understanding...
  47. ncbi request reprint Screening for hepatocellular carcinoma in clinical practice: miles to go before we sleep
    Eric R Kallwitz
    J Clin Gastroenterol 41:729-30. 2007
  48. ncbi request reprint Provider-patient in-office discussions of response to hepatitis C antiviral therapy and impact on patient comprehension
    Heidi E Hamilton
    Georgetown University, Washington, DC, USA
    Clin Gastroenterol Hepatol 4:507-13. 2006
    ....
  49. ncbi request reprint Productive replication of hepatitis C virus in perihepatic lymph nodes in vivo: implications of HCV lymphotropism
    Sampa Pal
    Department of Laboratory Medicine, University of Washington Medical Center, Seattle, Washington 98104, USA
    Gastroenterology 130:1107-16. 2006
    ..The pathogenesis of chronic hepatitis C is poorly understood. This study examines the ability of hepatitis C virus (HCV) to infect, replicate in, and produce progeny virus from perihepatic lymph nodes in vivo...
  50. doi request reprint Care of the liver transplant patient
    Eric R Kallwitz
    Dis Mon 54:486-507. 2008