Daniela Cota

Summary

Affiliation: University of Cincinnati
Country: USA

Publications

  1. ncbi CB1 receptors: emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health
    Daniela Cota
    Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    Diabetes Metab Res Rev 23:507-17. 2007
  2. doi The role of the endocannabinoid system in the regulation of hypothalamic-pituitary-adrenal axis activity
    D Cota
    Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    J Neuroendocrinol 20:35-8. 2008
  3. ncbi Cannabinoids, opioids and eating behavior: the molecular face of hedonism?
    Daniela Cota
    Obesity Research Center, Department of Psychiatry, University of Cincinnati Genome Research Institute, 2170 E Galbraith Road, Cincinnati, OH 45237, USA
    Brain Res Rev 51:85-107. 2006
  4. doi Role of the endocannabinoid system in energy balance regulation and obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45237, USA
    Front Horm Res 36:135-45. 2008
  5. pmc Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system
    Karine Proulx
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, OH, USA
    Diabetes 57:3231-8. 2008
  6. doi Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio, USA
    Obesity (Silver Spring) 17:1641-5. 2009
  7. pmc The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio 45237, USA
    J Neurosci 28:7202-8. 2008
  8. ncbi Hypothalamic mTOR signaling regulates food intake
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, 2170 East Galbraith Road, Cincinnati, OH 45237, USA
    Science 312:927-30. 2006
  9. doi Regulation of food intake through hypothalamic signaling networks involving mTOR
    Stephen C Woods
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio 45237, USA
    Annu Rev Nutr 28:295-311. 2008
  10. ncbi The role of CNS fuel sensing in energy and glucose regulation
    Daniela Cota
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio 45237, USA
    Gastroenterology 132:2158-68. 2007

Detail Information

Publications16

  1. ncbi CB1 receptors: emerging evidence for central and peripheral mechanisms that regulate energy balance, metabolism, and cardiovascular health
    Daniela Cota
    Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    Diabetes Metab Res Rev 23:507-17. 2007
    ..Thus, pharmacologic options targeting the ECS may provide a novel, effective approach to the prevention and management of CVD, type 2 diabetes and obesity...
  2. doi The role of the endocannabinoid system in the regulation of hypothalamic-pituitary-adrenal axis activity
    D Cota
    Department of Psychiatry, Obesity Research Center, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    J Neuroendocrinol 20:35-8. 2008
    ..Altogether, these observations suggest that alterations of the endocannabinoid tone might be associated with the development of stress-related diseases, including anxiety, depression and obesity...
  3. ncbi Cannabinoids, opioids and eating behavior: the molecular face of hedonism?
    Daniela Cota
    Obesity Research Center, Department of Psychiatry, University of Cincinnati Genome Research Institute, 2170 E Galbraith Road, Cincinnati, OH 45237, USA
    Brain Res Rev 51:85-107. 2006
    ....
  4. doi Role of the endocannabinoid system in energy balance regulation and obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Cincinnati, OH 45237, USA
    Front Horm Res 36:135-45. 2008
    ....
  5. pmc Fatty acid synthase inhibitors modulate energy balance via mammalian target of rapamycin complex 1 signaling in the central nervous system
    Karine Proulx
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, OH, USA
    Diabetes 57:3231-8. 2008
    ..The purpose of these experiments was to determine whether hypothalamic mTOR complex 1 (mTORC1) signaling is involved in mediating the effects of FAS inhibitors...
  6. doi Food intake-independent effects of CB1 antagonism on glucose and lipid metabolism
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio, USA
    Obesity (Silver Spring) 17:1641-5. 2009
    ..These effects are independent of the anorectic action of the drug...
  7. pmc The role of hypothalamic mammalian target of rapamycin complex 1 signaling in diet-induced obesity
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, Cincinnati, Ohio 45237, USA
    J Neurosci 28:7202-8. 2008
    ..Overall, these findings point strongly to the possibility that reduced hypothalamic mTORC1 signaling contributes to the development of hyperphagia, weight gain, and leptin resistance during diet-induced obesity...
  8. ncbi Hypothalamic mTOR signaling regulates food intake
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, 2170 East Galbraith Road, Cincinnati, OH 45237, USA
    Science 312:927-30. 2006
    ..Thus, mTOR is a cellular fuel sensor whose hypothalamic activity is directly tied to the regulation of energy intake...
  9. doi Regulation of food intake through hypothalamic signaling networks involving mTOR
    Stephen C Woods
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio 45237, USA
    Annu Rev Nutr 28:295-311. 2008
    ....
  10. ncbi The role of CNS fuel sensing in energy and glucose regulation
    Daniela Cota
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, Ohio 45237, USA
    Gastroenterology 132:2158-68. 2007
    ..The corollary to this hypothesis is that dysregulation of these fuel-sensing mechanisms in the brain may contribute to metabolic dysregulation underlying diseases, such as obesity and type 2 diabetes...
  11. ncbi Leptin in energy balance and reward: two faces of the same coin?
    Daniela Cota
    Department of Psychiatry, University of Cincinnati, Genome Research Institute, 2170 East Galbraith Road, Ohio 45237, USA
    Neuron 51:678-80. 2006
    ..In this issue of Neuron, Hommel et al. reveal a novel site for leptin's regulation of feeding. In turn, Fulton et al. propose a novel role for leptin in regulating non-feeding-related motivated behaviors...
  12. ncbi The integrative role of CNS fuel-sensing mechanisms in energy balance and glucose regulation
    Darleen Sandoval
    Department of Psychiatry, Genome Research Institute, University of Cincinnati, Cincinnati, OH 45237, USA
    Annu Rev Physiol 70:513-35. 2008
    ..Consequently, dysfunction of the ability of the CNS to integrate fuel-sensing signals may underlie the etiology of metabolic diseases such as obesity and diabetes...
  13. ncbi Mechanisms of oleoylethanolamide-induced changes in feeding behavior and motor activity
    Karine Proulx
    Genome Research Institute, ML 0506, University of Cincinnati, 2170 E Galbraith Road, Cincinnati, OH 45237, USA
    Am J Physiol Regul Integr Comp Physiol 289:R729-37. 2005
    ..Despite that OEA-induced anorexia is unlikely to be due to impaired motor activity, our data raise a cautionary note in how specific behavioral and metabolic effects of OEA should be interpreted...
  14. pmc The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
    Daniela Cota
    Clinical Neuroendocrinology Group, Max Planck Institute of Psychiatry, Munich, Germany
    J Clin Invest 112:423-31. 2003
    ....
  15. ncbi The emerging role of the endocannabinoid system in endocrine regulation and energy balance
    Uberto Pagotto
    Endocrinology Unit, Department of Internal Medicine and Gastroenterology, Sant Orsola Malpighi Hospital, Bologna, Italy, and Department of Physiological Chemistry, Johannes Gutenberg University Mainz, Germany
    Endocr Rev 27:73-100. 2006
    ..The relevance of the system is further strenghtened by the notion that drugs interfering with the activity of the endocannabinoid system are considered as promising candidates for the treatment of various diseases, including obesity...
  16. ncbi Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function
    Daniela Cota
    Group of Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
    Endocrinology 148:1574-81. 2007
    ....