William Coryell

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi request reprint Hyperactivity of the hypothalamic-pituitary-adrenal axis and mortality in major depressive disorder
    William Coryell
    Department of Psychiatry, University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242 1000, USA
    Psychiatry Res 142:99-104. 2006
  2. pmc HPA-axis hyperactivity and mortality in psychotic depressive disorder: preliminary findings
    William Coryell
    Department of Psychiatry, University of Iowa Carver College of Medicine, 2 205 MEB, Iowa City, IA 52242, USA
    Psychoneuroendocrinology 33:654-8. 2008
  3. pmc Anxiety and outcome in bipolar disorder
    William Coryell
    Department of Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, 52242, USA
    Am J Psychiatry 166:1238-43. 2009
  4. ncbi request reprint Psychosocial disability and work role function compared across the long-term course of bipolar I, bipolar II and unipolar major depressive disorders
    Lewis L Judd
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0603, USA
    J Affect Disord 108:49-58. 2008
  5. doi request reprint Residual symptom recovery from major affective episodes in bipolar disorders and rapid episode relapse/recurrence
    Lewis L Judd
    Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0603, USA
    Arch Gen Psychiatry 65:386-94. 2008
  6. pmc Effects of anxiety on the long-term course of depressive disorders
    William Coryell
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins, Iowa City, IA 52242, USA
    Br J Psychiatry 200:210-5. 2012
  7. pmc Age of onset and the prospectively observed course of illness in bipolar disorder
    William Coryell
    Department of Psychiatry, University of Iowa, Carver College of Medicine, 500 Newton Road, Iowa City, IA 52231 1190, United States
    J Affect Disord 146:34-8. 2013
  8. doi request reprint Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20
    Jessica Ross
    Department of Psychiatry, University of California, San Francisco, CA 94132 0984, USA
    Psychiatr Genet 18:191-8. 2008
  9. pmc Combined biological tests for suicide prediction
    William Coryell
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, 2 205 MEB, Iowa City, IA 52242 1000, USA
    Psychiatry Res 150:187-91. 2007
  10. doi request reprint Family-based association of FKBP5 in bipolar disorder
    V L Willour
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Mol Psychiatry 14:261-8. 2009

Detail Information

Publications43

  1. ncbi request reprint Hyperactivity of the hypothalamic-pituitary-adrenal axis and mortality in major depressive disorder
    William Coryell
    Department of Psychiatry, University of Iowa, Roy J and Lucille A Carver College of Medicine, Iowa City, IA 52242 1000, USA
    Psychiatry Res 142:99-104. 2006
    ..Because nearly all previous reports of DST results and suicide described depressed inpatients, it is possible that the DST is a useful predictor only within this population...
  2. pmc HPA-axis hyperactivity and mortality in psychotic depressive disorder: preliminary findings
    William Coryell
    Department of Psychiatry, University of Iowa Carver College of Medicine, 2 205 MEB, Iowa City, IA 52242, USA
    Psychoneuroendocrinology 33:654-8. 2008
    ..Among the possible mediators is the hypothalamic-pituitary-adrenal (HPA)-axis hyperactivity that characterizes many cases of relatively severe depressive disorder and severity is characteristic of psychotic depressive disorder...
  3. pmc Anxiety and outcome in bipolar disorder
    William Coryell
    Department of Psychiatry, University of Iowa Hospitals and Clinics, Iowa City, 52242, USA
    Am J Psychiatry 166:1238-43. 2009
    ..The authors sought to identify the anxiety features most predictive of subsequent affective morbidity and to evaluate the persistence of the prognostic relationship...
  4. ncbi request reprint Psychosocial disability and work role function compared across the long-term course of bipolar I, bipolar II and unipolar major depressive disorders
    Lewis L Judd
    Department of Psychiatry, University of California at San Diego, La Jolla, CA 92093 0603, USA
    J Affect Disord 108:49-58. 2008
    ....
  5. doi request reprint Residual symptom recovery from major affective episodes in bipolar disorders and rapid episode relapse/recurrence
    Lewis L Judd
    Department of Psychiatry, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0603, USA
    Arch Gen Psychiatry 65:386-94. 2008
    ..Both bipolar disorder type I and type II are characterized by frequent affective episode relapse and/or recurrence. An increasingly important goal of therapy is reducing chronicity by preventing or delaying additional episodes...
  6. pmc Effects of anxiety on the long-term course of depressive disorders
    William Coryell
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins, Iowa City, IA 52242, USA
    Br J Psychiatry 200:210-5. 2012
    ..Important questions remain as to which anxiety features are important to outcome and how sustained their prognostic effects are over time...
  7. pmc Age of onset and the prospectively observed course of illness in bipolar disorder
    William Coryell
    Department of Psychiatry, University of Iowa, Carver College of Medicine, 500 Newton Road, Iowa City, IA 52231 1190, United States
    J Affect Disord 146:34-8. 2013
    ..To test the validity of age-of-onset grouping in bipolar disorder through the use of prospectively observed time in mood episodes...
  8. doi request reprint Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20
    Jessica Ross
    Department of Psychiatry, University of California, San Francisco, CA 94132 0984, USA
    Psychiatr Genet 18:191-8. 2008
    ..Our aim is to map chromosomal regions that harbor loci that increase susceptibility to bipolar disorder...
  9. pmc Combined biological tests for suicide prediction
    William Coryell
    Department of Psychiatry, Roy J and Lucille A Carver College of Medicine, 2 205 MEB, Iowa City, IA 52242 1000, USA
    Psychiatry Res 150:187-91. 2007
    ..These results indicate that, with the use of age-appropriate thresholds, serum cholesterol concentrations may be combined with DST results to provide a clinically useful estimate of suicide risk...
  10. doi request reprint Family-based association of FKBP5 in bipolar disorder
    V L Willour
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Mol Psychiatry 14:261-8. 2009
    ..Ongoing whole-genome association studies in bipolar disorder and major depression should further clarify the role of FKBP5 and other HPA genes in these illnesses...
  11. ncbi request reprint A prospective investigation of the natural history of the long-term weekly symptomatic status of bipolar II disorder
    Lewis L Judd
    Department of Psychiatry, University of California, San Diego, La Jolla 92093 0603, USA
    Arch Gen Psychiatry 60:261-9. 2003
    ..This is the first prospective longitudinal study, to our knowledge, of the natural history of the weekly symptomatic status of bipolar II disorder (BP-II)...
  12. ncbi request reprint Onset of spontaneous panic attacks: a prospective study of risk factors
    William Coryell
    University of Iowa Carver College of Medicine, Department of Psychiatry, 2 205 MEB, Iowa City, IA 52242, USA
    Psychosom Med 68:754-7. 2006
    ..An association of those features with a subsequent onset of panic attacks would compose additional evidence that they are trait markers for panic disorder...
  13. ncbi request reprint Rapid cycling bipolar disorder: clinical characteristics and treatment options
    William Coryell
    Psychiatry Research Department, University of Iowa, Carver College of Medicine, Iowa City, Iowa 52242, USA
    CNS Drugs 19:557-69. 2005
    ..The combination of lithium and carbamazepine, valproate or lamotrigine for maintenance has some support from controlled studies, as does the adjunctive use of olanzapine...
  14. ncbi request reprint The prospectively observed course of illness among depressed patients who commit suicide
    William Coryell
    Department of Psychiatry, University of Iowa, Iowa City 52242 1000, USA
    Acta Psychiatr Scand 105:218-23. 2002
    ..These analyses were conducted to describe the course of illness among patients with major affective disorders who commit suicide...
  15. ncbi request reprint The long-term course of rapid-cycling bipolar disorder
    William Coryell
    National Institute of Mental Health Collaborative Program on the Psychobiology of Depression Clinical Studies, National Institutes of Health, Bethesda, MD, USA
    Arch Gen Psychiatry 60:914-20. 2003
    ..To our knowledge, no prospective study has, as yet, described the course of this phenomenon beyond 5 years...
  16. doi request reprint Effects of escitalopram on anxiety and respiratory responses to carbon dioxide inhalation in subjects at high risk for panic disorder: a placebo-controlled, crossover study
    William Coryell
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    J Clin Psychopharmacol 29:174-8. 2009
    ....
  17. pmc Genetic association of bipolar disorder with the β(3) nicotinic receptor subunit gene
    Sarah M Hartz
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA
    Psychiatr Genet 21:77-84. 2011
    ....
  18. doi request reprint Familial aggregation of postpartum mood symptoms in bipolar disorder pedigrees
    Jennifer L Payne
    Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA
    Bipolar Disord 10:38-44. 2008
    ..We sought to determine if postpartum mood symptoms and depressive episodes exhibit familial aggregation in bipolar I pedigrees...
  19. ncbi request reprint Comorbid major depression and panic disorder: significance of temporal sequencing to familial transmission
    Lilian Dindo
    Psychiatry Research, Department of Psychiatry, College of Medicine, University of Iowa, MEB 2 202, Iowa City, IA 52242 1000, USA
    J Affect Disord 82:119-23. 2004
    ..Our aim was to determine if the risk for depression in a proband is influenced by the temporal sequence of comorbid PD and major depression in an affected family member...
  20. pmc Challenges assessing clinical endpoints in early Huntington disease
    Jane S Paulsen
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242 1000, USA
    Mov Disord 25:2595-603. 2010
    ..We conclude that future clinical trials designed for very early disease will require the development of new and more sensitive measures of real-life function...
  21. pmc Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans
    David T Dao
    Department of Psychiatry, University of Maryland School of Medicine, Baltimore, 21201, USA
    Biol Psychiatry 68:801-10. 2010
    ..Recent genome-wide association studies have associated polymorphisms in the gene CACNA1C, which codes for Ca(v)1.2, with a bipolar disorder and depression diagnosis...
  22. ncbi request reprint Psychosocial disability in the course of bipolar I and II disorders: a prospective, comparative, longitudinal study
    Lewis L Judd
    Department of Psychiatry, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0603, USA
    Arch Gen Psychiatry 62:1322-30. 2005
    ..Evidence of psychosocial disability in bipolar disorder is based primarily on bipolar I disorder (BP-I) and does not relate disability to affective symptom severity and polarity or to bipolar II disorder (BP-II)...
  23. doi request reprint Maintenance treatment in bipolar disorder: a reassessment of lithium as the first choice
    William Coryell
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    Bipolar Disord 11:77-83. 2009
    ..In consideration of the declining use of lithium over the past several decades, this review focuses on three topics to argue for lithium's status as first choice as the maintenance treatment of bipolar disorder...
  24. pmc CAG-repeat length and the age of onset in Huntington disease (HD): a review and validation study of statistical approaches
    Douglas R Langbehn
    Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1000, USA
    Am J Med Genet B Neuropsychiatr Genet 153:397-408. 2010
    ..The Langbehn et al. model appears accurate enough to have substantial utility in various research contexts. We also emphasize remaining caveats, many of which are relevant for any direct application to genetic counseling...
  25. ncbi request reprint Anxiety responses to CO2 inhalation in subjects at high-risk for panic disorder
    William Coryell
    University of Iowa Carver College of Medicine, Iowa City, USA
    J Affect Disord 92:63-70. 2006
    ..The following was undertaken to confirm and extend these findings...
  26. ncbi request reprint Clinical predictors of suicide in primary major depressive disorder
    William Coryell
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    J Clin Psychiatry 66:412-7. 2005
    ..The following analysis takes advantage of a large cohort of depressed patients given detailed, structured interviews 2 decades ago...
  27. ncbi request reprint Is perinatal depression familial?
    Kathleen Murphy-Eberenz
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 3309, USA
    J Affect Disord 90:49-55. 2006
    ....
  28. ncbi request reprint Subgenual prefrontal cortex volumes in major depressive disorder and schizophrenia: diagnostic specificity and prognostic implications
    William Coryell
    Department of Psychiatry, 2 205 MEB, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, IA 52242 1000, USA
    Am J Psychiatry 162:1706-12. 2005
    ..There are, as yet, few data to address the specificity of these abnormalities to depressive disorders or to characterize their stability over time...
  29. ncbi request reprint Suicide and the hypothalamic-pituitary-adrenal axis
    Elizabeth A Young
    Department of Psychiatry and Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Lancet 366:959-61. 2005
  30. ncbi request reprint The comparative clinical phenotype and long term longitudinal episode course of bipolar I and II: a clinical spectrum or distinct disorders?
    Lewis L Judd
    National Institute of Mental Health Collaborative Program on the Psychobiology of Depression Clinical Studies, USA
    J Affect Disord 73:19-32. 2003
    ....
  31. ncbi request reprint A 20-year longitudinal observational study of somatic antidepressant treatment effectiveness
    Andrew C Leon
    NIMH Collaborative Program on the Psychobiology of Depression, USA
    Am J Psychiatry 160:727-33. 2003
    ..This observational study examined the effectiveness of somatic antidepressant treatments as administered in the community...
  32. ncbi request reprint Distinguishing bipolar major depression from unipolar major depression with the screening assessment of depression-polarity (SAD-P)
    David A Solomon
    Department of Psychiatry and Human Behavior, Brown University, Providence, RI, USA
    J Clin Psychiatry 67:434-42. 2006
    ..The goal of this study was to develop and validate a brief instrument to screen for bipolar disorder in patients actively ill with major depression...
  33. ncbi request reprint The course of depression in elderly patients
    Timothy I Mueller
    Brown University Medical School, Department of Psychiatry and Human Behavior, c o Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Am J Geriatr Psychiatry 12:22-9. 2004
    ..Studies on the course of major depressive disorder (MDD) among elderly persons are limited to short periods of follow-up, seldom provide comparisons with younger cohorts, and raise other methodological concerns...
  34. ncbi request reprint Mood-incongruent psychotic features in bipolar disorder: familial aggregation and suggestive linkage to 2p11-q14 and 13q21-33
    Fernando S Goes
    Johns Hopkins Hospital, 600 North Wolfe St, Meyer 4 119, Baltimore, MD 21287 7419, USA
    Am J Psychiatry 164:236-47. 2007
    ..This study attempts to characterize clinical correlates, familial aggregation, and genetic linkage in subjects with these features...
  35. ncbi request reprint Loci on chromosomes 6q and 6p interact to increase susceptibility to bipolar affective disorder in the national institute of mental health genetics initiative pedigrees
    Thomas G Schulze
    Genetic Basis of Mood and Anxiety Disorders, Mood and Anxiety Program, Bethesda, USA
    Biol Psychiatry 56:18-23. 2004
    ....
  36. ncbi request reprint Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin
    Sven Cichon
    Nat Genet 36:783-4; author reply 784-5. 2004
  37. pmc Predicting recovery from episodes of major depression
    David A Solomon
    Department of Psychiatry and Human Behavior, The Warren Alpert Medical School of Brown University, Providence, RI 02903 4970, United States
    J Affect Disord 107:285-91. 2008
    ..This study examined psychosocial functioning as a predictor of recovery from episodes of unipolar major depression...
  38. ncbi request reprint Psychosocial impairment and recurrence of major depression
    David A Solomon
    Department of Psychiatry and Human Behavior, Brown University, Providence, RI, USA
    Compr Psychiatry 45:423-30. 2004
    ..In patients who have recovered from an episode of major depression, the presence of psychosocial impairment may help identify who is at increased risk of recurrence...
  39. ncbi request reprint Tachyphylaxis in unipolar major depressive disorder
    David A Solomon
    Department of Psychiatry and Human Behavior, Brown University, 593 Eddy Street, Providence, RI 02903, USA
    J Clin Psychiatry 66:283-90. 2005
    ..This study describes recurrence of major depression despite maintenance pharmacotherapy, termed tachyphylaxis...
  40. pmc Genomewide linkage analyses of bipolar disorder: a new sample of 250 pedigrees from the National Institute of Mental Health Genetics Initiative
    Danielle M Dick
    Institute of Psychiatric Research, Indiana University School of Medicine, 791 Union Drive, Indianapolis, IN 46202 4887, USA
    Am J Hum Genet 73:107-14. 2003
    ..10), on chromosomes 2p, 3q, and 8q. This study, which is based on the largest linkage sample for bipolar disorder analyzed to date, indicates that several genes contribute to bipolar disorder...
  41. pmc Whole-genome association study of bipolar disorder
    P Sklar
    Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA
    Mol Psychiatry 13:558-69. 2008
    ..Given the heritability of BP disorder, the lack of agreement between studies emphasizes that susceptibility alleles are likely to be modest in effect size and require even larger samples for detection...
  42. ncbi request reprint Long-term symptomatic status of bipolar I vs. bipolar II disorders
    Lewis L Judd
    National Institute of Mental Health Collaborative Program on the Psychobiology of Depression Clinical Studies, San Diego, La Jolla, CA, USA
    Int J Neuropsychopharmacol 6:127-37. 2003
    ..However the genetic variation underlying such a putative spectrum remains to be clarified...