Research Topics
Genomes and GenesSpecies | Victoria K CortessisSummaryAffiliation: University of Southern California Country: USA Publications
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Detail Information
Publications
Repeated assessment by high-throughput assay demonstrates that sperm DNA methylation levels are highly reproducibleVictoria K Cortessis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
Fertil Steril 96:1325-30. 2011..To assess reliability of a high-throughput assay of sperm DNA methylation...
A case-control study of cyclin D1 CCND1 870A-->G polymorphism and bladder cancerVictoria K Cortessis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, CA 90033, USA
Carcinogenesis 24:1645-50. 2003..90, 95% confidence interval 0.60-1.33). The null association was not appreciably modified by bladder cancer risk factors, including lifetime smoking history, or by histopathologic classification...
Risk of urinary bladder cancer is associated with 8q24 variant rs9642880[T] in multiple racial/ethnic groups: results from the Los Angeles-Shanghai case-control studyVictoria K Cortessis
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Ave, MC 9175, Los Angeles, CA 90089, USA
Cancer Epidemiol Biomarkers Prev 19:3150-6. 2010..Recent genome-wide association studies of urinary bladder cancer report risk to be associated with the T allele of rs9642880 on 8q24 among individuals of European descent...
Sequence variant on 3q28 and urinary bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control studyMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
Cancer Epidemiol Biomarkers Prev 18:3057-61. 2009..045). Our results suggest that a TP63 gene variant may increase susceptibility for the development of urinary bladder tumors with low risk of progression...
Hypertension, diuretics and antihypertensives in relation to bladder cancerXuejuan Jiang
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Carcinogenesis 31:1964-71. 2010..7 pg/g Hb) compared with individuals without hypertension (79.8 pg/g Hb) (P = 0.009). In conclusion, untreated hypertension was associated with a reduced risk of bladder cancer...
Genetic variations on chromosomes 5p15 and 15q25 and bladder cancer risk: findings from the Los Angeles-Shanghai bladder case-control studyManuela Gago-Dominguez
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089 9175, USA
Carcinogenesis 32:197-202. 2011..26; 95% CI, 1.04-1.54; P = 0.017). Our results support 5p15 and 15q25 as susceptibility regions for bladder cancer risk...
Cigarette smoking and subtypes of bladder cancerXuejuan Jiang
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
Int J Cancer 130:896-901. 2012..Our results indicate that cigarette smoking was more strongly associated with increased risk of invasive bladder cancer than with low-grade superficial bladder cancer...
Heterogenous effect of androgen receptor CAG tract length on testicular germ cell tumor risk: shorter repeats associated with seminoma but not other histologic typesCarol A Davis-Dao
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90033, USA
Carcinogenesis 32:1238-43. 2011....
Water intake and bladder cancer risk in Los Angeles CountyXuejuan Jiang
USC Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
Int J Cancer 123:1649-56. 2008..Similarly, the protection from water intake was confined to women who did not experience nocturia and to men who did. Results from our study suggest that water intake may be associated with a slight reduction in bladder cancer risk...
Combination of molecular alterations and smoking intensity predicts bladder cancer outcome: A report from the Los Angeles Cancer Surveillance ProgramAnirban P Mitra
Department of Pathology, University of Southern California, Los Angeles, California Center for Personalized Medicine, University of Southern California, Los Angeles, California
Cancer 119:756-65. 2013....
Shorter androgen receptor CAG repeat lengths associated with cryptorchidism risk among Hispanic white boysCarol Davis-Dao
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Children s Hospital Los Angeles, 1441 Eastlake Avenue, MC 9175, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 97:E393-9. 2012..Androgens are essential for testicular descent, and functional genetic polymorphisms in the androgen receptor gene (AR) are postulated to influence cryptorchidism risk...
Widespread epigenetic abnormalities suggest a broad DNA methylation erasure defect in abnormal human spermSahar Houshdaran
Department of Biochemistry and Molecular Biology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
PLoS ONE 2:e1289. 2007..Incomplete reprogramming of the male germ line could, in theory, result in both altered sperm DNA methylation and compromised spermatogenesis...
Environmental epigenetics: prospects for studying epigenetic mediation of exposure-response relationshipsVictoria K Cortessis
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, USC Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
Hum Genet 131:1565-89. 2012..We discuss some of the challenges in studying epigenetic mediation of pathogenesis and describe some unique opportunities for exploring these phenomena...
Lower risk in parous women suggests that hormonal factors are important in bladder cancer etiologyCarol A Davis-Dao
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Cancer Epidemiol Biomarkers Prev 20:1156-70. 2011..Our objective was to determine whether hormonal and reproductive factors are involved in female bladder cancer...
Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancerMariana C Stern
Department of Preventive Medicine, Keck School of Medicine, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA
Cancer Res 69:6857-64. 2009..002) and was strongest for the highest levels of smoking dose and smoking duration. Overall, our study provides the strongest evidence to date for a role of common variants in DNA repair genes in bladder carcinogenesis...
Cryptorchidism and testicular germ cell tumors: comprehensive meta-analysis reveals that association between these conditions diminished over time and is modified by clinical characteristicsKimberly Banks
Keck School of Medicine, University of Southern California Los Angeles, CA, USA City of Hope National Medical Center Duarte, CA, USA St Joseph Hospital Orange, CA, USA
Front Endocrinol (Lausanne) 3:182. 2012..Based on available data, CO patients and their parents or caregivers should be made aware of elevated TGCT risk following orchidopexy, regardless of age at repair, unilateral vs. bilateral non-descent, or position of undescended testes...
Alcohol consumption and risk of bladder cancer in Los Angeles CountyXuejuan Jiang
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Int J Cancer 121:839-45. 2007..Alcohol consumption was strongly associated with a reduced risk of bladder cancer. The effect was modified by the type of alcoholic beverage, cigarette smoking and frequency of urination...
RUNX3 methylation reveals that bladder tumors are older in patients with a history of smokingErika M Wolff
Department of Urology, Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, California 90089, USA
Cancer Res 68:6208-14. 2008..Because RUNX3 methylation is acquired early on in tumorigenesis, then its detection in biopsy or urine specimens could provide a marker to screen cigarette smokers long before any symptoms of bladder cancer are present...
A molecular/epidemiologic analysis of expression of cyclooxygenases 1 and 2, use of nonsteroidal antiinflammatory drugs, and risk of colorectal adenomaRobert W Haile
USC Norris Cancer Center, Keck School of Medicine, Department of Preventive Medicine, University of Southern California, 1441 Eastlake Ave, Suite 4455, Los Angeles, CA 90033, USA
Clin Colorectal Cancer 4:390-5. 2005..The results suggest that at least part of the protective effect of NSAIDs on the risk of colorectal adenoma involves a COX-mediated pathway...
Population-based case-control study of recreational drug use and testis cancer risk confirms an association between marijuana use and nonseminoma riskJohn Charles A Lacson
Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089 9175, USA
Cancer 118:5374-83. 2012..Here, the authors evaluate the relation between TGCTs and exposure to marijuana and other recreational drugs using a population-based case-control study...
A genome-wide meta-analysis of nodular sclerosing Hodgkin lymphoma identifies risk loci at 6p21.32Wendy Cozen
Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
Blood 119:469-75. 2012..In a separate analysis, the DRB1*0701 allele was associated with a decreased risk of NSHL (OR = 0.5, 95% confidence interval = 0.4, 0.7). These data support the importance of the HLA class II region in NSHL etiology...
Male infertility and variation in CAG repeat length in the androgen receptor gene: a meta-analysisCarol A Davis-Dao
Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, MC 9175, Los Angeles, California 90033, USA
J Clin Endocrinol Metab 92:4319-26. 2007..Many studies have investigated the association between male infertility and trinucleotide repeat polymorphisms in the androgen receptor (AR) gene, but no comprehensive meta-analysis of all published studies has been conducted...
Effect of cervicitis on visual inspection with acetic acidCarol A Davis-Dao
Department of Preventive Medicine, University of Southern California, Keck School of Medicine, Los Angeles, CA, USA
J Low Genit Tract Dis 12:282-6. 2008..The objective of this study was to determine whether the presence of cervicitis influenced the accuracy of visual inspection with acetic acid (VIA)...
Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control studyMarc J Gunter
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS, 6120 Executive Boulevard, Rockville, MD 20852, USA
Carcinogenesis 26:637-42. 2005..49 (95% CI, 0.28-0.85)]. We did not identify any association with consumption of individual HCAs and colorectal adenoma risk. These results support the hypothesis that BP contributes to colorectal carcinogenesis...
Mutation analysis of INSL3 and GREAT/LGR8 genes in familial cryptorchidismShu Feng
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
Urology 64:1032-6. 2004..Thus, mutations in these two genes are responsible only for a small proportion of familial cryptorchidism...
Re: Prepubertal orchiopexy for cryptorchidism may be associated with lower risk of testicular cancerEllenie Tuazon
J Urol 180:783-4; author reply 784-5. 2008
