J Corren

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Safety and tolerability of omalizumab
    J Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    Clin Exp Allergy 39:788-97. 2009
  2. doi request reprint Use of mometasone furoate administered via a dry powder inhaler in the treatment of asthma
    Michelle Zeidler
    David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Curr Med Res Opin 26:1295-305. 2010
  3. pmc Mometasone furoate in the management of asthma: a review
    Ricardo A Tan
    California Allergy and Asthma Medical Group, Los Angeles, CA
    Ther Clin Risk Manag 4:1201-8. 2008
  4. doi request reprint Role of interleukin-13 in asthma
    Jonathan Corren
    Department of Medicine, Section of Clinical Immunology and Allergy, University of California, 10780 Santa Monica Blvd, Suite 280, Los Angeles, CA, 90025, USA
    Curr Allergy Asthma Rep 13:415-20. 2013
  5. doi request reprint Efficacy and safety of fluticasone/formoterol combination therapy in patients with moderate-to-severe asthma
    Jonathan Corren
    Allergy Medical Clinic, 10780 Santa Monica Blvd, Suite 280, Los Angeles, CA 90025, USA
    Respir Med 107:180-95. 2013
  6. ncbi request reprint Inhibition of interleukin-5 for the treatment of eosinophilic diseases
    Jonathan Corren
    Department of Medicine, University of California, Los Angeles, 10780 Santa Monica Blvd, Suite 280, Los Angeles, California 90025, USA
    Discov Med 13:305-12. 2012
  7. ncbi request reprint Efficacy and safety of budesonide and formoterol in asthma
    Jonathan Corren
    11620 Wilshire Blvd, Allergy Medical Clinic, Los Angeles, CA, 90025
    Hosp Pract (Minneap) 37:162-3. 2009
  8. doi request reprint Cytokine inhibition in severe asthma: current knowledge and future directions
    Jonathan Corren
    Research Division, Allergy Medical Clinic, Los Angeles, California 90025, USA
    Curr Opin Pulm Med 17:29-33. 2011
  9. doi request reprint Anti-interleukin-5 antibody therapy in asthma and allergies
    Jonathan Corren
    Allergy Medical Clinic, Los Angeles, California, USA
    Curr Opin Allergy Clin Immunol 11:565-70. 2011
  10. ncbi request reprint Twelve-week, randomized, placebo-controlled, multicenter study of the efficacy and tolerability of budesonide and formoterol in one metered-dose inhaler compared with budesonide alone and formoterol alone in adolescents and adults with asthma
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    Clin Ther 29:823-43. 2007

Detail Information

Publications43

  1. doi request reprint Safety and tolerability of omalizumab
    J Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    Clin Exp Allergy 39:788-97. 2009
    ..Omalizumab (Xolair) is a recombinant humanized monoclonal anti-IgE antibody with proven efficacy in patients with moderate-to-severe and severe persistent allergic (IgE-mediated) asthma...
  2. doi request reprint Use of mometasone furoate administered via a dry powder inhaler in the treatment of asthma
    Michelle Zeidler
    David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Curr Med Res Opin 26:1295-305. 2010
    ..Mometasone furoate delivered via a dry powder inhaler (MF-DPI) is indicated for once-daily maintenance treatment of asthma in patients as young as 4 years old...
  3. pmc Mometasone furoate in the management of asthma: a review
    Ricardo A Tan
    California Allergy and Asthma Medical Group, Los Angeles, CA
    Ther Clin Risk Manag 4:1201-8. 2008
    ..Twice-daily dosing with MF has been demonstrated to successfully allow for reduction or elimination of oral corticosteroids in severe asthmatics...
  4. doi request reprint Role of interleukin-13 in asthma
    Jonathan Corren
    Department of Medicine, Section of Clinical Immunology and Allergy, University of California, 10780 Santa Monica Blvd, Suite 280, Los Angeles, CA, 90025, USA
    Curr Allergy Asthma Rep 13:415-20. 2013
    ..These data indicate that IL-13 antagonists may fulfill an important unmet need in patients with poorly controlled asthma and biologic evidence of persistent IL-13 activity. ..
  5. doi request reprint Efficacy and safety of fluticasone/formoterol combination therapy in patients with moderate-to-severe asthma
    Jonathan Corren
    Allergy Medical Clinic, 10780 Santa Monica Blvd, Suite 280, Los Angeles, CA 90025, USA
    Respir Med 107:180-95. 2013
    ..i.d.) via a single aerosol inhaler, with the individual components (fluticasone 250 μg b.i.d.; formoterol 10 μg b.i.d.), in adult and adolescent patients with moderate-to-severe asthma...
  6. ncbi request reprint Inhibition of interleukin-5 for the treatment of eosinophilic diseases
    Jonathan Corren
    Department of Medicine, University of California, Los Angeles, 10780 Santa Monica Blvd, Suite 280, Los Angeles, California 90025, USA
    Discov Med 13:305-12. 2012
    ..Strategies aimed at the inhibition of IL-5 may hold great promise in the treatment of eosinophilic diseases...
  7. ncbi request reprint Efficacy and safety of budesonide and formoterol in asthma
    Jonathan Corren
    11620 Wilshire Blvd, Allergy Medical Clinic, Los Angeles, CA, 90025
    Hosp Pract (Minneap) 37:162-3. 2009
    ..Efficacy and safety of budesonide and formoterol in one pressurised metered-dose inhaler in adults and adolescents with moderate to severe asthma: a randomised clinical trial. Drugs. 2006;66(17):2235-2254...
  8. doi request reprint Cytokine inhibition in severe asthma: current knowledge and future directions
    Jonathan Corren
    Research Division, Allergy Medical Clinic, Los Angeles, California 90025, USA
    Curr Opin Pulm Med 17:29-33. 2011
    ..Existing data from clinical trials of cytokine antagonists in asthmatic patients are then reviewed to determine the efficacy and safety of these compounds...
  9. doi request reprint Anti-interleukin-5 antibody therapy in asthma and allergies
    Jonathan Corren
    Allergy Medical Clinic, Los Angeles, California, USA
    Curr Opin Allergy Clin Immunol 11:565-70. 2011
    ....
  10. ncbi request reprint Twelve-week, randomized, placebo-controlled, multicenter study of the efficacy and tolerability of budesonide and formoterol in one metered-dose inhaler compared with budesonide alone and formoterol alone in adolescents and adults with asthma
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    Clin Ther 29:823-43. 2007
    ....
  11. ncbi request reprint Small airways disease in asthma
    Jonathan Corren
    Allergy Research Foundation, University of California, Los Angeles, 11620 Wilshire Boulevard 200, Los Angeles, CA 90025, USA
    Curr Allergy Asthma Rep 8:533-9. 2008
    ..The recognition of small airways involvement in asthma has clinical relevance, as new formulations of inhaled corticosteroids with smaller particle aerosols may be more effective in addressing this component of asthma...
  12. doi request reprint Effects of omalizumab on changes in pulmonary function induced by controlled cat room challenge
    Jonathan Corren
    Allergy Medical Clinic, Research Division, Los Angeles, CA, USA
    J Allergy Clin Immunol 127:398-405. 2011
    ..Environmental exposure to cat allergen is common, and sensitization to cat allergens is strongly associated with asthma...
  13. pmc Clinical and biochemical effects of a combination botanical product (ClearGuard) for allergy: a pilot randomized double-blind placebo-controlled trial
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, USA
    Nutr J 7:20. 2008
    ..The current study was conducted to determine the effects of these combined ingredients upon the nasal response to allergen challenge in patients with seasonal allergic rhinitis...
  14. doi request reprint Allergen skin tests and free IgE levels during reduction and cessation of omalizumab therapy
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    J Allergy Clin Immunol 121:506-11. 2008
    ..It is not known whether stopping or reducing the dose of omalizumab maintains adequate suppression of free IgE levels and IgE-mediated mast cell activation...
  15. doi request reprint A randomized, controlled, phase 2 study of AMG 317, an IL-4Ralpha antagonist, in patients with asthma
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    Am J Respir Crit Care Med 181:788-96. 2010
    ..AMG 317 is a fully human monoclonal antibody to IL-4Ralpha that blocks both IL-4 and IL-13 pathways...
  16. ncbi request reprint Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
    W Busse
    Department of Medicine, University of Wisconsin Hospital and Clinics, University of Wisconsin, Madison, 53792, USA
    J Allergy Clin Immunol 108:184-90. 2001
    ..CONCLUSION: The addition of omalizumab to standard asthma therapy reduces asthma exacerbations and decreases inhaled corticosteroid and rescue medication use...
  17. ncbi request reprint Effects of zafirlukast upon clinical, physiologic, and inflammatory responses to natural cat allergen exposure
    J Corren
    Allergy Research Foundation, Inc, Los Angeles, California 90025, USA
    Ann Allergy Asthma Immunol 87:211-7. 2001
    ..However, it is unknown whether these drugs modulate airway inflammation after exposure to allergen in a natural setting...
  18. ncbi request reprint Effective control of asthma with hydrofluoroalkane flunisolide delivered as an extrafine aerosol in asthma patients
    J Corren
    Allergy Research Foundation, Inc, Los Angeles, California 90023, USA
    Ann Allergy Asthma Immunol 87:405-11. 2001
    ..Inhaled corticosteroids are established as maintenance therapy for persistent asthma. A new aerosol formulation of flunisolide delivers a small particle size by using a hydrofluoroalkane (HFA) propellant with a built-in spacer...
  19. ncbi request reprint Comparison of once-daily mometasone furoate versus once-daily budesonide in patients with moderate persistent asthma
    J Corren
    Allergy Research Foundation, Los Angeles, California 90025, USA
    Int J Clin Pract 57:567-72. 2003
    ..In conclusion, once-daily treatment in the morning with MF-DPI 440 microg significantly improved pulmonary function and asthma control compared with morning administration of BUD-DPI 400 microg and placebo...
  20. ncbi request reprint Evaluation of efficacy and safety of flunisolide hydrofluoroalkane for the treatment of asthma
    Jonathan Corren
    Allergy Research Foundation, Inc, Los Angeles, California 90023, USA
    Clin Ther 25:776-98. 2003
    ..HFA replaces the chlorofluorocarbon (CFC) propellant of the previous formulation, producing aerosols of smaller average particle size...
  21. ncbi request reprint Pneumococcal seroconversion after vaccination for children with atopic dermatitis treated with tacrolimus ointment
    E Richard Stiehm
    Mattel Children s Hospital, University of California Los Angeles, California 90095, USA
    J Am Acad Dermatol 53:S206-13. 2005
    ..We sought to determine the effect of treatment with topical tacrolimus on B- and T-cell immunity including the primary antibody response to pneumococcal polysaccharide vaccine in children with atopic dermatitis...
  22. doi request reprint Daclizumab improves asthma control in patients with moderate to severe persistent asthma: a randomized, controlled trial
    William W Busse
    Department of Medicine, Section of Allergy, Pulmonary, and Critical Care Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
    Am J Respir Crit Care Med 178:1002-8. 2008
    ..The mechanism of action likely involves inhibition of proinflammatory cytokine generation by IL-2R blockade in activated T cells. Clinical trial registered with www.clinicaltrials.gov (NCT00028288)...
  23. ncbi request reprint Evaluation and treatment of asthma: an overview
    Jonathan Corren
    David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
    Am J Manag Care 11:S408-15; quiz S427-33. 2005
    ..Asthma is a chronic, inflammatory condition that requires diligent long-term follow-up. This article will address the diagnostic evaluation of patients with asthma and present an overview of drugs commonly used in treatment...
  24. ncbi request reprint Effects of omalizumab, a humanized monoclonal anti-IgE antibody, on nasal reactivity to allergen and local IgE synthesis
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, California 90025, USA
    Ann Allergy Asthma Immunol 93:243-8. 2004
    ..Treatment with omalizumab has been shown to reduce serum free IgE concentrations and to have beneficial effects on allergic airway disease. However, its effect on IgE synthesis is unknown...
  25. ncbi request reprint Immunomodulation of asthma: where do we stand?
    Jonathan Corren
    Allergy Research Foundation, 11620 Wilshire Boulevard, Suite 200 210, Los Angeles, CA 90025, USA
    Curr Allergy Asthma Rep 2:433-5. 2002
  26. ncbi request reprint Hydrofluoroalkane formulations of inhaled corticosteroids for the treatment of asthma
    Michelle Zeidler
    Department of Pulmonary and Critical Care Medicine, University of California, Los Angeles, California 90025, USA
    Treat Respir Med 3:35-44. 2004
    ..Future studies, involving histopathologic and clinical endpoints, will be necessary to determine whether treatment with HFA solutions offers significant advantages over currently available therapies...
  27. ncbi request reprint Relationship between nonallergic upper airway disease and asthma
    Jonathan Corren
    Department of Medicine, University of California, Los Angeles, California, USA
    Clin Allergy Immunol 19:101-14. 2007
    ..Finally, given this complex relationship between localized and systemic inflammation, it behooves all physicians to assess and treat rhinitis and sinusitis when they are present in patients with asthma...
  28. ncbi request reprint Rhinitis therapy and the prevention of hospital care for asthma: a case-control study
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, CA 90025, USA
    J Allergy Clin Immunol 113:415-9. 2004
    ..Although clinical trials have demonstrated that rhinitis therapy improves subjective and objective measures of asthma, it is uncertain whether treatment of allergic rhinitis significantly affects the frequency of asthma exacerbations...
  29. ncbi request reprint The connection between allergic rhinitis and bronchial asthma
    Jonathan Corren
    Allergy Research Foundation, Los Angeles, California 90025, USA
    Curr Opin Pulm Med 13:13-8. 2007
    ..The relationship between allergic rhinitis and asthma has intrigued practicing physicians since the turn of the century. Investigations during the past two decades have led to an increased understanding of this relationship...
  30. ncbi request reprint Omalizumab, a recombinant humanized anti-IgE antibody, reduces asthma-related emergency room visits and hospitalizations in patients with allergic asthma
    Jonathan Corren
    Allergy Research Foundation, Inc, Los Angeles, Calif 90025, USA
    J Allergy Clin Immunol 111:87-90. 2003
    ..Prevention of serious asthma exacerbations is an important therapeutic goal in patients with asthma...
  31. ncbi request reprint Small airways response to naturalistic cat allergen exposure in subjects with asthma
    Michelle R Zeidler
    Division of Pulmonary, David Geffen School of Medicine and Allergy Research Foundation, University of California, Los Angeles, CA 90025, USA
    J Allergy Clin Immunol 118:1075-81. 2006
    ..It is currently unclear whether the small airways (diameter <2 microm) contribute significantly to late asthmatic reactions to inhaled allergen...
  32. ncbi request reprint Review of azelastine nasal spray in the treatment of allergic and non-allergic rhinitis
    Christina Lee
    Department of Medicine, Division of Pulmonary and Critical Care Medicine, Section of Clinical Immunology and Allergy, University of California, Los Angeles, Los Angeles, CA, USA
    Expert Opin Pharmacother 8:701-9. 2007
    ..Given its unique pharmacologic properties and clinical profile, azelastine maintains an important role in the treatment of chronic rhinitis...
  33. ncbi request reprint Effectiveness of azelastine nasal spray compared with oral cetirizine in patients with seasonal allergic rhinitis
    Jonathan Corren
    Allergy Research Foundation, Inc, Los Angeles, California 90025, USA
    Clin Ther 27:543-53. 2005
    ..Azelastine nasal spray and oral cetirizine are selective histamine H(1)-receptor antagonists that are approved in the United States for the treatment of seasonal allergic rhinitis (SAR)...
  34. ncbi request reprint Efficacy of once-daily desloratadine/pseudoephedrine for relief of nasal congestion
    Eric Schenkel
    Valley Clinical Research Center, 3729 Easton Nazareth Highway, Suite 202, Easton, PA 18045, USA
    Allergy Asthma Proc 23:325-30. 2002
    ..It was concluded that desloratadine/pseudoephedrine offers additional benefit to patients with moderate-to-severe SAR-associated nasal congestion compared with pseudoephedrine therapy alone...
  35. ncbi request reprint Omalizumab is effective in the long-term control of severe allergic asthma
    Bobby Quentin Lanier
    Lanier Education and Research Network, Fort Worth, Texas, USA
    Ann Allergy Asthma Immunol 91:154-9. 2003
    ..Previous reports show that addition of omalizumab to standard therapy reduces asthma exacerbations and simultaneously decreases use of inhaled corticosteroids (ICSs) and rescue medication in patients with allergic asthma...
  36. ncbi request reprint Protective effect of montelukast on lower and upper respiratory tract responses to short-term cat allergen exposure
    Tamara T Perry
    Division of Allergy and Immunology, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Ann Allergy Asthma Immunol 93:431-8. 2004
    ..Challenge with short-term exposure to airborne cat allergen in sensitized patients produces pulmonary function changes and rhinitis symptoms...
  37. doi request reprint A cumulative dose study of levalbuterol and racemic albuterol administered by hydrofluoroalkane-134a metered-dose inhaler in asthmatic subjects
    Kenneth Tripp
    Sepracor, Inc, Marlborough, MA 01752, USA
    J Allergy Clin Immunol 122:544-9. 2008
    ..The short-acting beta(2)-agonists levalbuterol and racemic albuterol are available for administration through a hydrofluoroalkane-134a (HFA) metered-dose inhaler (MDI)...
  38. ncbi request reprint Efficacy and safety of azelastine nasal spray at a dose of 1 spray per nostril twice daily
    William Lumry
    AARA Research Center, Dallas, Texas 75231, USA
    Ann Allergy Asthma Immunol 99:267-72. 2007
    ..Azelastine hydrochloride nasal spray is available worldwide for the treatment of seasonal allergic rhinitis (SAR) and perennial allergic rhinitis. One spray per nostril twice daily is the most commonly recommended dose...
  39. ncbi request reprint The rhinitis-asthma link revisited
    Jonathan Corren
    Ann Allergy Asthma Immunol 94:311-2. 2005
  40. ncbi request reprint Efficacy of azelastine nasal spray in seasonal allergic rhinitis patients who remain symptomatic after treatment with fexofenadine
    Craig F LaForce
    Carolina Allergy and Asthma Consultants, Raleigh, North Carolina 27607, USA
    Ann Allergy Asthma Immunol 93:154-9. 2004
    ..Currently available oral second-generation antihistamines do not provide adequate symptom relief for many allergy patients...
  41. ncbi request reprint Addition of ibuprofen to pseudoephedrine and chlorpheniramine in the treatment of seasonal allergic rhinitis
    Eli O Meltzer
    Allergy and Asthma Medical Group and Research Center, San Diego, California, USA
    Ann Allergy Asthma Immunol 93:452-9. 2004
    ..Standard over-the-counter therapy with antihistamines and nasal decongestants often does not completely relieve all symptoms associated with allergic rhinitis...
  42. ncbi request reprint Incidence and characteristics of angioedema associated with enalapril
    John B Kostis
    Department of Medicine, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick 08903 0019, USA
    Arch Intern Med 165:1637-42. 2005
    ..Angioedema is a rare but potentially serious adverse event of angiotensin-converting enzyme inhibitor therapy. However, no prospective, controlled studies have reported on its incidence and clinical characteristics...
  43. ncbi request reprint Nasal response to natural cat allergen exposure is significantly greater in patients with rhinitis and asthma than in patients with rhinitis alone
    Jonathan Corren
    J Allergy Clin Immunol 115:202-3. 2005