Research Topics
| Maria M CorradaSummaryAffiliation: University of California Country: USA Publications
| Collaborators
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Detail Information
Publications
Apolipoprotein E genotype, dementia, and mortality in the oldest old: The 90+ StudyMaria M Corrada
Department of Neurology, University of California, Irvine, CA, USA Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA Electronic address
Alzheimers Dement 9:12-8. 2013....- A population-based clinicopathological study in the oldest-old: the 90+ studyMaria M Corrada
Department of Neurology, University of California, Irvine, Irvine, CA 92697 1400, USA
Curr Alzheimer Res 9:709-17. 2012.... - Association of body mass index and weight change with all-cause mortality in the elderlyMaria M Corrada
Department of Neurology, School of Medicine, University of California, Irvine, 92697 1400, USA
Am J Epidemiol 163:938-49. 2006..This study highlights the influence on older-age mortality risk of being overweight or obese in young adulthood and underweight or obese in later life... - Dementia incidence continues to increase with age in the oldest old: the 90+ studyMaria M Corrada
Department of Neurology, University of California, Irvine, CA 92697 1400, USA
Ann Neurol 67:114-21. 2010..Here, we estimate age- and sex-specific incidence rates of all-cause dementia in people aged 90 years and older, including estimates for centenarians... 
Prevalence of dementia after age 90: results from the 90+ studyM M Corrada
Department of Neurology, University of California Irvine, Irvine, CA 92697 1400, USA
Neurology 71:337-43. 2008..Here, we estimate age- and sex-specific prevalence of all-cause dementia in the oldest-old, those aged 90 and older...- Alzheimer disease pathology and longitudinal cognitive performance in the oldest-old with no dementiaArchana B Balasubramanian
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, USA
Neurology 79:915-21. 2012..The purpose of this study was to compare longitudinal cognitive performance in oldest-old individuals without dementia with and without AD neuropathology... - Disability in the oldest-old: incidence and risk factors in the 90+ studyDaniel J Berlau
Department of Neurology, University of California Irvine, CA 92697, USA
Am J Geriatr Psychiatry 20:159-68. 2012..To measure the incidence of disability in individuals aged 90 years and older and examine factors that may increase risk of disability... - Cognitive impairment in nondemented oldest-old: prevalence and relationship to cardiovascular risk factorsCarrie B Peltz
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, USA
Alzheimers Dement 8:87-94. 2012..To determine the prevalence and types of cognitive impairment in a sample of nondemented participants aged ≥90 (the oldest-old) and to examine the relationships between cognitive impairment and cardiovascular risk factors... - Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-oldB Adar Kravitz
Department of Neurobiology and Behavior, University of California at Irvine, Irvine, CA, USA
Alzheimers Dement 5:318-23. 2009..Using a cross-sectional design, we examined whether high levels of serum CRP are associated with increased odds of prevalent dementia in the oldest-old... 
Synaptic proteins, neuropathology and cognitive status in the oldest-oldElizabeth Head
Institute of Brain Aging and Dementia, University of California, Irvine, CA 92697 4540, USA
Neurobiol Aging 30:1125-34. 2009..Frontal cortex SYN protein levels may protect neuronal function in oldest-old individuals and reflect compensatory responses that may be involved with maintaining cognition...- APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest oldDaniel J Berlau
Institute of Brain Aging and Dementia, University of California Irvine, Irvine, CA 92697 1400, USA
Neurology 72:829-34. 2009..This would predict, even with advanced age, that APOE2 carriers would be less likely to have dementia and less likely to meet pathologic criteria for AD... - High levels of serum C-reactive protein are associated with greater risk of all-cause mortality, but not dementia, in the oldest-old: results from The 90+ StudyB Adar Kravitz
Department of Neurobiology and Behavior, University of California at Irvine, Irvine, California, USA
J Am Geriatr Soc 57:641-6. 2009..To evaluate whether high levels of C-reactive protein (CRP) in serum are associated with greater risk of all-cause dementia or mortality in the oldest-old... - Operationalizing diagnostic criteria for Alzheimer's disease and other age-related cognitive impairment-Part 2Sudha Seshadri
Department of Neurology, Boston University School of Medicine, MA, USA
Alzheimers Dement 7:35-52. 2011..Improved accuracy in the clinical diagnosis of AD is anticipated with the addition of molecular and structural biomarkers in the next generation of epidemiological studies... - Alzheimer's and dementia in the oldest-old: a century of challengesClaudia H Kawas
Department of Neurology, University of California, Irvine, CA 92697 4540, USA
Curr Alzheimer Res 3:411-9. 2006.... - Incidence of dementia in oldest-old with amnestic MCI and other cognitive impairmentsCarrie B Peltz
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA
Neurology 77:1906-12. 2011..To examine the incidence of dementia among the oldest-old people with normal cognition and different types of cognitive impairment... - The prevalence of disability in the oldest-old is high and continues to increase with age: findings from The 90+ StudyDaniel J Berlau
Institute for Brain Aging and Dementia, University of California, Irvine, USA
Int J Geriatr Psychiatry 24:1217-25. 2009..To examine the prevalence and type of disability in the oldest-old (90+), the fastest growing age group in the United States... - Poor physical performance and dementia in the oldest old: the 90+ studySzofia S Bullain
Department of Neurology, University of California, Irvine, CA 92967, USA
JAMA Neurol 70:107-13. 2013..To examine the cross-sectional relationship between physical performance and dementia in the oldest old (those ≥ 90 years of age)... - Non-alcoholic beverage and caffeine consumption and mortality: the Leisure World Cohort StudyAnnlia Paganini-Hill
Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, CA, USA
Prev Med 44:305-10. 2007..To examine the effects of non-alcoholic beverage and caffeine consumption on all-cause mortality in older adults... - Diagnosing dementia in the oldest-oldCarrie Brumback-Peltz
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA 92697 4540, United States
Maturitas 70:164-8. 2011..More research is necessary in the oldest-old to better understand the etiologies of dementia in this age group, and factors that may affect the expression of disease as we age... - Neuropsychological data in nondemented oldest old: the 90+ StudyChristina Whittle
Institute of Brain Aging and Dementia, University of California, Irvine, CA, USA
J Clin Exp Neuropsychol 29:290-9. 2007..Cognitive performance declined with age for two-thirds of the tests. Performance on some tests was also affected by gender, education, and depression scores... - Sensitivity and specificity of the mini-mental state examination for identifying dementia in the oldest-old: the 90+ studyKristin Kahle-Wrobleski
Institute of Brain Aging and Dementia, University of California at Irvine, Irvine, California 92697, USA
J Am Geriatr Soc 55:284-9. 2007..To evaluate the sensitivity and specificity of the Mini-Mental State Examination (MMSE) in identifying dementia in the oldest-old when stratified by age and education... - Visual memory predicts Alzheimer's disease more than a decade before diagnosisC H Kawas
Alzheimer s Disease Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Neurology 60:1089-93. 2003.... - Amyloid imaging and cognitive decline in nondemented oldest-old: the 90+ StudyClaudia H Kawas
Department of Neurology, University of California, Irvine, Irvine, CA, USA
Alzheimers Dement 9:199-203. 2013..The goal of this study was to examine cross-sectional and longitudinal associations between cognitive performance and beta amyloid (Aβ) load determined by florbetapir F18 positron emission tomography (PET) in nondemented oldest-old... - DRD4 genotype predicts longevity in mouse and humanDeborah L Grady
Department of Biological Chemistry, College of Medicine, University of California, Irvine, California 92697, USA
J Neurosci 33:286-91. 2013..These results support the hypothesis that DRD4 gene variants contribute to longevity in humans and in mice, and suggest that this effect is mediated by shaping behavioral responses to the environment... - Estrogen replacement therapy, Alzheimer's disease, and mild cognitive impairmentRuth A Mulnard
Departments of Neurology, and Neurobiology and Behavior, University of California Irvine, Gillespie NRF, Room 1113, Irvine, CA 92697 4540, USA
Curr Neurol Neurosci Rep 4:368-73. 2004..Additional basic and clinical investigations are necessary to examine different forms and dosages of estrogens, other populations, and the relevance of timing and duration of exposure...