EAIN CORNFORD

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Acute upregulation of blood-brain barrier glucose transporter activity in seizures
    E M Cornford
    Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, 90095, USA
    Am J Physiol Heart Circ Physiol 279:H1346-54. 2000
  2. ncbi Human cerebral cysticercosis: immunolocalization of a sodium-dependent glucose cotransporter (SGLT) in larval and adult tapeworms
    E M Cornford
    Department of Neurology, Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Parasitol 87:510-21. 2001
  3. ncbi New systems for delivery of drugs to the brain in neurological disease
    Eain M Cornford
    Department of Neurology and the Brain Research Institute, UCLA, and The Department of Veterans Affairs, Los Angeles, 90095 1769, USA
    Lancet Neurol 1:306-15. 2002
  4. ncbi Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy
    Eain M Cornford
    Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
    NeuroRx 2:27-43. 2005
  5. ncbi Tegumental glucose permeability in male and female Schistosoma mansoni
    E M Cornford
    Comprehensive Epilepsy Program, V A Wadsworth Medical Center, Los Angeles, California 90073
    J Parasitol 74:116-28. 1988
  6. ncbi Immunogold detection of microvascular proteins in the compromised blood-brain barrier
    Eain M Cornford
    Department of Neurology, Brain Research Institute, UCLA School of Medicine, Los Angeles, CA, USA
    Methods Mol Med 89:161-75. 2003

Research Grants

  1. Trojan horse gene therapy of inclusion body disease
    Eain M Cornford; Fiscal Year: 2010
  2. PET AND THE BLOOD BRAIN BARRIER IN HUMAN EPILEPSY
    EAIN CORNFORD; Fiscal Year: 2002
  3. Blood-brain barrier gene delivery in knock-out mice.
    EAIN CORNFORD; Fiscal Year: 2005
  4. Trojan horse gene therapy of inclusion body disease
    EAIN CORNFORD; Fiscal Year: 2007

Detail Information

Publications6

  1. ncbi Acute upregulation of blood-brain barrier glucose transporter activity in seizures
    E M Cornford
    Department of Neurology, University of California, Los Angeles School of Medicine, Los Angeles, 90095, USA
    Am J Physiol Heart Circ Physiol 279:H1346-54. 2000
    ..80 +/- 0.25 micromol. min(-1). g(-1)). We conclude acute upregulation of BBB glucose transport occurs within 3 min of an initial seizure. Transporter V(max) and BBB glucose permeability increase by 30-40%...
  2. ncbi Human cerebral cysticercosis: immunolocalization of a sodium-dependent glucose cotransporter (SGLT) in larval and adult tapeworms
    E M Cornford
    Department of Neurology, Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90095, USA
    J Parasitol 87:510-21. 2001
    ..Furthermore, high expression of this cotransporter was seen in the branches of the uterus, suggesting that SGLT-mediated absorption of glucose and water has an important functional role within the reproductive system of adult tapeworms...
  3. ncbi New systems for delivery of drugs to the brain in neurological disease
    Eain M Cornford
    Department of Neurology and the Brain Research Institute, UCLA, and The Department of Veterans Affairs, Los Angeles, 90095 1769, USA
    Lancet Neurol 1:306-15. 2002
    ..These conjugates have been shown to remain functionally active and effective in animal models of neurological disease...
  4. ncbi Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy
    Eain M Cornford
    Veterans Administration Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
    NeuroRx 2:27-43. 2005
    ....
  5. ncbi Tegumental glucose permeability in male and female Schistosoma mansoni
    E M Cornford
    Comprehensive Epilepsy Program, V A Wadsworth Medical Center, Los Angeles, California 90073
    J Parasitol 74:116-28. 1988
    ..Gender- and mating-specific analyses of PS products indicate that tegumental permeability to glucose is significantly increased in mated schistosomes, and compares very favorably to that of the host liver...
  6. ncbi Immunogold detection of microvascular proteins in the compromised blood-brain barrier
    Eain M Cornford
    Department of Neurology, Brain Research Institute, UCLA School of Medicine, Los Angeles, CA, USA
    Methods Mol Med 89:161-75. 2003

Research Grants9

  1. Trojan horse gene therapy of inclusion body disease
    Eain M Cornford; Fiscal Year: 2010
    ..v. injections which suppresses Lafora body burdens for 6-12 months in knock-out mice. Examinations of BBB integrity and capillary tight-junctions will show the absence of microvascular pathology, even after chronic PIL treatments ..
  2. PET AND THE BLOOD BRAIN BARRIER IN HUMAN EPILEPSY
    EAIN CORNFORD; Fiscal Year: 2002
    ..abstract_text> ..
  3. Blood-brain barrier gene delivery in knock-out mice.
    EAIN CORNFORD; Fiscal Year: 2005
    ..abstract_text> ..
  4. Trojan horse gene therapy of inclusion body disease
    EAIN CORNFORD; Fiscal Year: 2007
    ..v. injections which suppresses Lafora body burdens for 6-12 months in knock-out mice. Examinations of BBB integrity and capillary tight-junctions will show the absence of microvascular pathology, even after chronic PIL treatments ..