Research Topics
| Amanda H CorbettSummaryAffiliation: University of North Carolina Country: USA Publications
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Detail Information
Publications
Fosamprenavir. Vertex Pharmaceuticals/GlaxoSmithKlineAmanda H Corbett
School of Pharmacy, The University of North Carolina Hospitals, Chapel Hill 27514, USA
Curr Opin Investig Drugs 3:384-90. 2002..In September 2000 and January 2001, Merrill Lynch predicted a 2002 launch, with sales of pounds sterling 50 million in 2002, rising to pounds sterling 150 million in 2004...
Pharmacokinetics of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian childrenAmanda H Corbett
University of North Carolina Schools of Pharmacy, Medicine and Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Antivir Ther 15:83-90. 2010....- Dose separation does not overcome the pharmacokinetic interaction between fosamprenavir and lopinavir/ritonavirAmanda H Corbett
School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Antimicrob Agents Chemother 50:2756-61. 2006..67 [0.54 to 0.83] and 0.77 [0.59 to 0.99], respectively) compared to simultaneous administration. Additional investigations are warranted to determine the optimal dosing of FPV with LPV/RTV... - Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxisJulie B Dumond
School of Pharmacy, University of North Carolina at Chapel Hill, North Carolina, USA
AIDS 21:1899-907. 2007..To describe first dose and steady state antiretroviral drug exposure in the female genital tract... - The pharmacokinetics, safety, and initial virologic response of a triple-protease inhibitor salvage regimen containing amprenavir, saquinavir, and ritonavirAmanda H Corbett
Schools of Pharmacy and Medicine, University of North Carolina Center for AIDS Research, University of North Carolina at Chapel Hill, 27599, USA
J Acquir Immune Defic Syndr 36:921-8. 2004..These data suggest that amprenavir/saquinavir/ritonavir may be a viable salvage regimen in heavily PI-experienced individuals. New formulations of amprenavir and saquinavir may simplify this regimen... - Plasma bile acid concentrations in patients with human immunodeficiency virus infection receiving protease inhibitor therapy: possible implications for hepatotoxicityMarypeace McRae
University of North Carolina at Chapel Hill, 27599 7360, USA
Pharmacotherapy 30:17-24. 2010.... - Kaletra (lopinavir/ritonavir)Amanda H Corbett
School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7360, USA
Ann Pharmacother 36:1193-203. 2002..It may be used as a component of initial therapy or salvage therapy; future studies will better define its place in therapy... - Exploration of CYP450 and drug transporter genotypes and correlations with nevirapine exposure in MalawiansKevin C Brown
University of North Carolina at Chapel Hill, Eshelman School of Pharmacy, 3202 Kerr Hall, Chapel Hill, NC 27599 7569, USA
Pharmacogenomics 13:113-21. 2012..Genetic polymorphisms have the potential to influence drug metabolism and vary among ethnic groups. This study evaluated the correlation of genetic polymorphisms with nevirapine pharmacokinetics exposure in Malawians... - Simultaneous determination of 17 antiretroviral drugs in human plasma for quantitative analysis with liquid chromatography-tandem mass spectrometryByung Hwa Jung
Clinical Pharmacology and Analytical Chemistry Core, Center for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Biomed Chromatogr 21:1095-104. 2007..This method is very effective for quantifying and screening antiretroviral drugs in clinical samples with limited (50 microL) volumes... - Self-report of current and prior antiretroviral drug use in comparison to the medical record among HIV-infected patients receiving primary HIV careEmily Suzanne Brouwer
Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA
Pharmacoepidemiol Drug Saf 20:432-9. 2011..In this study we assessed the ability of HIV-infected patients receiving care in a university infectious diseases clinic to accurately recall current and past ARVs... 
Implementation of targeted interventions to decrease antiretroviral-related errors in hospitalized patientsLindsay M Daniels
Department ofPharmacy, University of North Carolina Hospitals, Chapel Hill, NC 27514, USA
Am J Health Syst Pharm 69:422-30. 2012..The implementation and effectiveness of targeted interventions aimed at decreasing the frequency of antiretroviral-related errors in hospitalized patients with human immunodeficiency virus (HIV) are described...- Frequency of HIV-related medication errors and associated risk factors in hospitalized patientsSonak D Pastakia
Department of Pharmacy Practice, School of Pharmacy and Pharmaceutical Sciences, Purdue University, Indianapolis, IN 46202, USA
Ann Pharmacother 42:491-7. 2008..Retrospective studies of hospitalized HIV-infected patients have noted a high occurrence of drug-related errors, ranging from 5% to 30%... - Pharmacokinetic comparison of generic and trade formulations of lamivudine, stavudine and nevirapine in HIV-infected Malawian adultsMina C Hosseinipour
University of North Carolina Project, Lilongwe Malawi
AIDS 21:59-64. 2007..The Malawian antiretroviral program uses generic Triomune (stavudine, lamivudine, and nevirapine)... - Protease inhibitor and nonnucleoside reverse transcriptase inhibitor concentrations in the genital tract of HIV-1-infected womenSherene S Min
Schools of Medicine, University of North Carolina, Chapel Hill 27599-7360, USA
J Acquir Immune Defic Syndr 37:1577-80. 2004..Of 8 ARVs, CVF concentrations ranged from <10% to >100% of BP concentrations. These large differences in CVF penetration suggest that further research into ARV pharmacokinetics and drug efficacy in the FGT is necessary...