Research Topics
| G ContrerasSummaryAffiliation: University of Miami Country: USA Publications
Research Grants
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Detail Information
Publications
Maintenance therapies for proliferative lupus nephritis: mycophenolate mofetil, azathioprine and intravenous cyclophosphamideG Contreras
Division of Nephrology, Miller School of Medicine, University of Miami, Florida 33136, USA
Lupus 14:s33-8. 2005..Maintenance therapies with MMF or AZA following short-term CY induction in a sequential regimen are efficacious and safe for the treatment of high-risk patients with proliferative lupus nephritis...- Outcomes in African Americans and Hispanics with lupus nephritisG Contreras
Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Florida 33136, USA
Kidney Int 69:1846-51. 2006..Our results suggest that both biological factors indicating an aggressive disease and low household income are common in African Americans and Hispanics with lupus nephritis, and outcomes in these groups are worse than in Caucasians... - Factors associated with poor outcomes in patients with lupus nephritisG Contreras
Acute Dialysis Unit Jackson Memorial Hospital, University of Miami Miller School of Medicine, Miami, FL 33101, USA
Lupus 14:890-5. 2005..We concluded that hypertension and elevated serum creatinine at the time of the kidney biopsy as well as a high CI are associated with an increased the risk for chronic renal failure or death in patients with lupus nephritis... 
Kidney transplantation outcomes in African-, Hispanic- and Caucasian-Americans with lupusG Contreras
Division of Nephrology, University of Miami, Miller School of Medicine, 1120 NW 14th Street, Suite 360E, Miami, FL 33136, USA
Lupus 21:3-12. 2012..26 [95% confidence interval 0.78-2.04]). African-Americans with lupus have high prevalence of risk factors for allograft failure that can explain poor outcomes...
Malnutrition-inflammation modifies the relationship of cholesterol with cardiovascular diseaseGabriel Contreras
Department of Medicine, Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 360E, Miami, FL 33136, USA
J Am Soc Nephrol 21:2131-42. 2010..In the M-I group, the corresponding HRs did not vary significantly by cholesterol level. In conclusion, the presence of M-I modifies the risk relationship between cholesterol level and CVD in African Americans with hypertensive CKD...- Sequential therapies for proliferative lupus nephritisGabriel Contreras
Dialysis Unit, Veterans Affairs Medical Center and University of Miami, Miami, USA
N Engl J Med 350:971-80. 2004..Long-term therapy with cyclophosphamide enhances renal survival in patients with proliferative lupus nephritis; however, the beneficial effect of cyclophosphamide must be weighed against its considerable toxic effects... - Blood pressure control, drug therapy, and kidney diseaseGabriel Contreras
University of Miami, Miami, FL, USA
Hypertension 46:44-50. 2005..These secondary analyses suggest a benefit of the low BP goal among patients assigned to amlodipine, but they must be interpreted cautiously... - Recurrence of lupus nephritis after kidney transplantationGabriel Contreras
Division of Nephrology, Miller School of Medicine, University of Miami, Miami, Florida 33136, USA
J Am Soc Nephrol 21:1200-7. 2010..Although RLN significantly increases the risk for graft failure, it contributes far less than rejection to its overall incidence; therefore, these findings should not keep patients with lupus from seeking a kidney transplant... - Differing effects of antihypertensive drugs on the incidence of diabetes mellitus among patients with hypertensive kidney diseaseDenyse Thornley-Brown
Division of Nephrology, University of Alabama at Birmingham, USA
Arch Intern Med 166:797-805. 2006..We compared the incidence of type 2 diabetes mellitus (DM) and the composite outcome of impaired fasting glucose or DM (IFG/DM) for the African American Study of Kidney Disease and Hypertension interventions... - New directions in the management of severe lupus nephritisO Lenz
Division of Nephrology and Hypertension, University of Miami Miller School of Medicine Miami, FL 33136, USA
Minerva Urol Nefrol 58:29-38. 2006.... - [The clinical impact of the physiological effects of erythropoietin and erythropoietin-stimulating agents on the incidence of malignancy, and hypertension: beyond anaemia]L M Ortega
Servicio de Nefrología e Hipertensión, Universidad de Miami Miller School of Medicine, Florida, Estados Unidos
Nefrologia 29:288-94. 2009.... - Treatment options for severe lupus nephritisOliver Lenz
Division of Nephrology and Hypertension, University of Miami, Miami, FL 33136, USA
Arch Immunol Ther Exp (Warsz) 52:356-65. 2004..This article discusses established and novel treatment options for patients with severe lupus nephritis corresponding to WHO classes III, IV, and V withIII or V with IV... - Successful blood pressure control in the African American Study of Kidney Disease and HypertensionJackson T Wright
Department of Medicine, Division of Hypertension, Case Western Reserve University, 10900 Euclid Ave, Wood Bldg, Room W-165, Cleveland, OH 44106-4982, USA
Arch Intern Med 162:1636-43. 2002..CONCLUSION: The blood pressure goals set and achieved in AASK participants clearly demonstrate that adequate blood pressure control can be achieved even in hypertensive populations whose blood pressure is the most difficult to control... - Salvage of problematic peritoneal dialysis cathetersArif Asif
Section of Interventional Nephrology, Division of Nephrology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Semin Dial 19:180-3. 2006..We conclude that in selected cases simple interventions can salvage problematic PD catheters and maintain patients on PD... - Defining the role of mycophenolate mofetil in the treatment of proliferative lupus nephritisOliver Lenz
Division of Nephrology and Hypertension, University of Miami Miller School of Medicine, Miami, Florida 33133, USA
Drugs 65:2429-36. 2005..In selected populations, induction with MMF is a reasonable option to reduce adverse events... - [Nephrogenic fibrosing dermopathy or nephrogenic systemic fibrosis? What do we know and what do we have to learn?]L M Ortega
Servicio de Nefrología e Hipertensión, Universidad de Miami, Miller School of Medicine, Miami, FL, USA
Nefrologia 29:109-17. 2009..Recommendations to guide the use of gadolinium based contrast agents in patients with underlying kidney disease should be individualized and considered in consultation with the ordering physician, radiologist and nephrologist... - Effect of hemodialysis on the signal-averaged electrocardiogramI Girgis
Divisions of Cardiology and Nephrology, University of Miami School of Medicine, Miami, FL, USA
Am J Kidney Dis 34:1105-13. 1999..Decreased left ventricular dimension because of fluid removal during HD is one possible explanation for this improvement... - Approach to the patient with hypertension, unexplained hypokalemia, and metabolic alkalosisC M Cely
Jackson Memorial Hospital, Miami, FL, USA
Am J Kidney Dis 37:E24. 2001..Our patient had an APARR, with an increase of aldosterone in the upright posture. The unusual physiologic response, incidence, and clinical characteristics of APARR are reviewed... - Sociodemographic factors contribute to the depressive affect among African Americans with chronic kidney diseaseMichael J Fischer
Department of Medicine, Jesse Brown VA Medical Center and University of Illinois Medical Center, Chicago, Illinois, USA
Kidney Int 77:1010-9. 2010..Sociodemographic factors have especially strong associations with this increased depressive affect. Because this study was conducted in an African-American cohort, its findings may not be generalized to other ethnic groups... - Impact of surgeon selection on access placement and survival following preoperative mapping in the "Fistula First" eraKenneth L Choi
Section of Interventional Nephrology, Division of Nephrology, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
Semin Dial 21:341-5. 2008..007). This analysis demonstrates that surgeon selection can have a significant impact on the rate of fistula placement and its overall survival despite similar findings on preoperative vascular mapping... - Utility of static pressure ratio recording during angioplasty of arteriovenous graft stenosisArif Asif
Division of Nephrology, Department of Medicine, University of Miami School of Medicine, Miami, Florida, USA
Semin Dial 19:551-6. 2006..33 +/- 0.02). Qa increased significantly in 74 of 83 (89%) procedures (before = 572 +/- 201, after = 1109 +/- 368 ml/min; p < 0.001). SPR measurements can assist in hemodynamic assessment of an AVG during angioplasty procedure... - Inhibitors of mTOR and risks of allograft failure and mortality in kidney transplantationT Isakova
The Division of Nephrology and Hypertension, Department of Medicine, University of Miami Miller School of Medicine, FL, USA
Am J Transplant 13:100-10. 2013..05-1.39) and the composite (HR 1.18; 95% CI, 1.08-1.30) in years 2-8. Compared with CNI-based regimens, use of an mTORI-based regimen for primary immunosuppression in kidney transplantation was associated with inferior recipient survival... - Predictors of alkalosis after liver transplantationGabriel Contreras
Veterans Affairs Medical Center and University of Miami School of Medicine, Miami, FL 33125, USA
Am J Kidney Dis 40:517-24. 2002..Metabolic alkalosis (MA) is common after orthotopic liver transplantation (OLT)... - A multicenter, prospective, randomized, comparative evaluation of dual- versus triple-lumen catheters for hemodialysis and apheresis in 485 patientsGabriel Contreras
Division of Nephrology, University of Miami School Medicine, Veterans Administration Medical Center, Miami, FL 33136, USA
Am J Kidney Dis 42:315-24. 2003..The purpose of this study is to compare a new temporary triple-lumen catheter (TLC) for dialysis that has a third lumen devoted to fluid and medication administration or blood sampling with a marketed dual-lumen catheter (DLC)... - Accuracy of ultrasound in the detection of inflow stenosis of arteriovenous fistulae: results of a prospective studyLoay Salman
Department of Medicine, Division of Nephrology, Section of Interventional Nephrology, University of Miami School of Medicine, Miami, Florida 33136, USA
Semin Dial 23:117-21. 2010..71, p<0.0001; slope=0.63+/-0.098 and intercept=24+/-6) and juxta-anastomotic stenosis (r2=0.71, p<0.0001; slope=0.68+/-0.060 and intercept=23+/-4). These results reveal that US has a high degree of accuracy in the detection of IS... - Secondary autogenous arteriovenous fistulas in the "fistula first" era: results of a longterm prospective studyLoay Salman
University of Miami Miller School of Medicine, Interventional Nephrology, Miami, FL 33136, USA
J Am Coll Surg 209:100-5. 2009..But their patency rates and the use of tunneled dialysis catheters during the postoperative period have not been reported in a prospective fashion... - Role of mycophenolate mofetil in the treatment of lupus nephritisGabriel Contreras
Clin J Am Soc Nephrol 2:879-82. 2007 - Prevalence and correlates of left ventricular hypertrophy in the African American Study of Kidney Disease Cohort StudyGail E Peterson
Division of Cardiology, University of Texas Southwestern Medical Center, 5909 Harry Hines Blvd, HA9 133, Dallas, TX 75235 9047, USA
Hypertension 50:1033-9. 2007.... - Metabolic syndrome, proteinuria, and the risk of progressive CKD in hypertensive African AmericansJanice Lea
Emory University, Atlanta, GA 30322, USA
Am J Kidney Dis 51:732-40. 2008..The purpose of this study is to examine whether metabolic syndrome is associated with kidney disease progression in hypertensive African Americans... - A comparison of iothalamate-GFR and serum creatinine-based outcomes: acceleration in the rate of GFR decline in the African American Study of Kidney Disease and HypertensionJulia Lewis
Nephrology Clinical Trials Center, Vanderbilt University Medical Center, 1211 21st Avenue South, 215 Medical Arts Building, Nashville, TN 37232 1371, USA
J Am Soc Nephrol 15:3175-83. 2004..This has important implications for the design of clinical trials with renal outcomes... - Long-term effects of renin-angiotensin system-blocking therapy and a low blood pressure goal on progression of hypertensive chronic kidney disease in African AmericansLawrence J Appel
Welch Center for Prevention, Epidemiology, and Clinical Research, The Johns Hopkins Institutions, Johns Hopkins University, Baltimore, MD 21205 2223, USA
Arch Intern Med 168:832-9. 2008..A low blood pressure (BP) goal (BP, <130/80 mm Hg) is also recommended. The objective of this study was to determine the long-term effects of currently recommended BP therapy in 1094 African Americans with hypertensive CKD... - Pulse pressure and inhibition of renin-angiotensin system in chronic kidney diseaseDebasish Banerjee
Department of Renal Medicine and Transplantation, St George s Hospital, Blackshaw Road, London SW17 0QT, UK
Nephrol Dial Transplant 21:975-8. 2006..The prognostic value of PP in pre-dialysis patients with chronic kidney disease (CKD) stages 4/5 and its interaction with renin-angiotensin system (RAS) inhibitors is unknown... - Angiotensin-converting enzyme gene polymorphism predicts the time-course of blood pressure response to angiotensin converting enzyme inhibition in the AASK trialVibha Bhatnagar
University of California San Diego, La Jolla, USA
J Hypertens 25:2082-92. 2007..It has yet to be determined whether genotyping at the angiotensin-converting enzyme (ACE) locus is predictive of blood pressure response to an ACE inhibitor... - Validation of creatinine-based estimates of GFR when evaluating risk factors in longitudinal studies of kidney diseaseXuelei Wang
Cleveland Clinic Foundation, Department of Quantitative Health Sciences, Wb 4, 9500 Euclid Avenue, Cleveland, OH 44195, USA
J Am Soc Nephrol 17:2900-9. 2006.... - Systemic lupus international collaborating clinics renal activity/response exercise: comparison of agreement in rating renal responseMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1789-95. 2008..To assess the degree to which physicians agree with each other and with ratings obtained with 3 existing responder indices, in rating the response to treatment of lupus nephritis... - Systemic lupus international collaborating clinics renal activity/response exercise: development of a renal activity score and renal response indexMichelle Petri
Department of Rheumatology, Johns Hopkins University, Baltimore, Maryland 21205, USA
Arthritis Rheum 58:1784-8. 2008..To develop a measure of renal activity in systemic lupus erythematosus and use it to develop a renal response index...
Research Grants
- African American Study of Kidney Disease and Hypertensi*Gabriel Contreras; Fiscal Year: 2007..Such results might eventually lead to new strategies that delay or prevent ESRD. ..