Nicholas K Conrad

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi Posttranscriptional gene regulation in Kaposi's sarcoma-associated herpesvirus
    Nicholas K Conrad
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9048, USA
    Adv Appl Microbiol 68:241-61. 2009
  2. ncbi Viral factors reveal a role for REF/Aly in nuclear RNA stability
    Sarah H Stubbs
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Mol Cell Biol 32:1260-70. 2012
  3. ncbi Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways
    Brooke B Sahin
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
    PLoS Pathog 6:e1000799. 2010
  4. ncbi Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity
    Emi Sei
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9048, USA
    Virology 419:107-16. 2011

Research Grants

  1. Mechanisms of KSHV post-transcriptional gene regulation
    Nicholas K Conrad; Fiscal Year: 2010

Collaborators

  • Sarah H Stubbs
  • Emi Sei
  • Brooke B Sahin
  • Olga V Hunter
  • Ashley Hoover
  • Denish Patel

Detail Information

Publications4

  1. ncbi Posttranscriptional gene regulation in Kaposi's sarcoma-associated herpesvirus
    Nicholas K Conrad
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9048, USA
    Adv Appl Microbiol 68:241-61. 2009
    ..With the growing appreciation of posttranscriptional regulation in cellular gene expression, it seems likely that the list of viral posttranscriptional regulatory schemes will expand as new details of KSHV gene regulation are uncovered...
  2. ncbi Viral factors reveal a role for REF/Aly in nuclear RNA stability
    Sarah H Stubbs
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Mol Cell Biol 32:1260-70. 2012
    ..These studies show that REF/Aly can stabilize nuclear RNAs independently of their export and support a broader conservation of RNA quality control mechanisms from yeast to humans...
  3. ncbi Kaposi's sarcoma-associated herpesvirus ORF57 protein binds and protects a nuclear noncoding RNA from cellular RNA decay pathways
    Brooke B Sahin
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
    PLoS Pathog 6:e1000799. 2010
    ..We propose that KSHV ORF57 protein functions to enhance the nuclear stability of intronless viral transcripts by protecting them from a cellular RNA quality control pathway...
  4. ncbi Delineation of a core RNA element required for Kaposi's sarcoma-associated herpesvirus ORF57 binding and activity
    Emi Sei
    Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9048, USA
    Virology 419:107-16. 2011
    ..These studies provide insight into ORF57 specificity determinants and lay a foundation for future analyses of cellular and viral ORF57 targets...

Research Grants1

  1. Mechanisms of KSHV post-transcriptional gene regulation
    Nicholas K Conrad; Fiscal Year: 2010
    ..A deeper understanding of KSHV gene regulation will lead to a more complete knowledge of this important human pathogen and may reveal aspects of gene regulation in its human host cell. ..