D J Conrad
Affiliation: University of California
- Cystic fibrosis therapy: a community ecology perspectiveDouglas Conrad
Division of Pulmonary and Critical Care Medicine, University of California at San Diego, San Diego Veterans Administration Healthcare System, 3350 La Jolla Village Drive, 111J, San Diego, CA 92122, USA
Am J Respir Cell Mol Biol 48:150-6. 2013..The resultant understanding of airway communities and their effects on lung physiology will facilitate the optimization of CF therapies...
- HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppressionDouglas Conrad
Harbor Biosciences, 9171 Towne Centre Drive, Suite 180, San Diego, CA 92122, USA
J Inflamm (Lond) 7:52. 2010..We tested the ability of this novel synthetic steroid with improved pharmacological properties to limit non-productive lung inflammation in rodents and attempted to gauge its immunological impact...
- Regulation of human 12/15-lipoxygenase by Stat6-dependent transcriptionD J Conrad
Section of Pulmonary and Critical Care, VA San Diego Healthcare System, the Veterans Medical Research Foundation, San Diego, CA 92161, USA
Am J Respir Cell Mol Biol 22:226-34. 2000..These data indicate that the human 12/15-lipoxygenase gene is induced in airway epithelial cells through Stat6-dependent transcriptional mechanisms mediated by a specific Stat6 response element in the 5'-flanking region...
- Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activationA C Wang
VA San Diego Healthcare System and the Veterans Medical Research Foundation, Section of Pulmonary and Critical Care, San Diego, California, USA
Am J Respir Cell Mol Biol 24:688-93. 2001..The demonstration of PPAR-gamma expression and function in airway epithelial cells expands the immunoregulatory role of PPARs and suggests a critical role for PPAR-gamma in antagonizing proinflammatory pathways in the airways...