Research Topics
| NADINE PATTAKOS CONNORSummaryAffiliation: University of Wisconsin Country: USA Publications
Research Grants
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Detail Information
Publications
Tongue muscle plasticity following hypoglossal nerve stimulation in aged ratsNadine P Connor
Department of Surgery, Otolaryngology Head and Neck Surgery, 600 Highland Avenue, Room K4 711, University of Wisconsin, Madison, Wisconsin 53792, USA
Muscle Nerve 47:230-40. 2013..Our hypothesis was that alterations in muscle contractile properties and myosin heavy chain composition would be found after NMES...
The effect of tongue exercise on serotonergic input to the hypoglossal nucleus in young and old ratsMary Behan
University of Wisconsin Madison, USA
J Speech Lang Hear Res 55:919-29. 2012..We hypothesized that tongue forces would increase with exercise, 5HT input to the tongue would decrease with age, and tongue exercise would augment 5HT input to the hypoglossal nucleus...
Effect of tongue exercise on protrusive force and muscle fiber area in aging ratsNadine P Connor
University of Wisconsin Clinical Science Center, Room K4 711, 600 Highland Avenue, Madison, WI 53792 7375, USA
J Speech Lang Hear Res 52:732-44. 2009..The authors' purpose was to investigate whether aged rats that have undergone tongue exercise would manifest increased protrusive tongue forces and increased genioglossus (GG) muscle fiber cross-sectional areas...
Differences in age-related alterations in muscle contraction properties in rat tongue and hindlimbNadine P Connor
University of Wisconsin Clinical Science Center, Madison, WI 53792 7375, USA
J Speech Lang Hear Res 51:818-27. 2008..Because of differences in muscle architecture and biomechanics, the purpose of this study was to determine whether muscle contractile properties of rat hindlimb and tongue were differentially affected by aging...
Attitudes of children with dysphoniaNadine P Connor
Department of Communicative Disorders, University of Wisconsin Madison, Madison, Wisconsin, USA
J Voice 22:197-209. 2008..Chronic dysphonia negatively affects the lives of children. This work will serve as the basis for development of a valid, reliable, and age-appropriate measure of voice-related quality of life in children...
Impact of conventional radiotherapy on health-related quality of life and critical functions of the head and neckNadine P Connor
Department of Otolaryngology Head and Neck Surgery, University of Wisconsin Medical School, and William S Middleton Memorial Veterans Hospital, Madison, WI 53792 7375, USA
Int J Radiat Oncol Biol Phys 65:1051-62. 2006..Head-and-neck radiotherapy is associated with significant morbidities. Our purpose was to document impact of morbidities by use of multiple objective measures and health-related quality of life (HR-QOL)...
Symptoms of extraesophageal reflux in a community-dwelling sampleNadine P Connor
Department of Communicative Disorders, University of Wisconsin Madison, Madison, Wisconsin, USA
J Voice 21:189-202. 2007..The authors' goal was to determine the prevalence of EERD and the effect on health-related quality of life in adults within a large community-based sample...
Movement-related skin strain associated with goal-oriented lip actionsN P Connor
Division of Otolaryngology Head and Neck Surgery, University of Wisconsin Clinical Science Center, Madison 53792, USA
Exp Brain Res 123:235-41. 1998..Further, the magnitude of multiple strains was predictive of lower-lip movement endpoints. These results highlight the potential importance of cutaneous mechanoreceptors as putative proprioceptors...
Ultrasonic output from the excised rat larynxAARON M JOHNSON
Department of Surgery, Clinical Science Center, University of Wisconsin Madison, 600 Highland Avenue, Madison, Wisconsin 53792, USA
J Acoust Soc Am 128:EL75-9. 2010....
A translational approach to vocalization deficits and neural recovery after behavioral treatment in Parkinson diseaseMichelle R Ciucci
Communicative Disorders, University of Wisconsin Madison, Madison, WI, USA
J Commun Disord 43:319-26. 2010..LEARNING OUTCOMES: Readers will gain an understanding of how a rat model of Parkinson disease is used to study vocalization deficits and interventions...
Targeted exercise therapy for voice and swallow in persons with Parkinson's diseaseJohn A Russell
University of Wisconsin School of Medicine and Public Health, Otolaryngology Head and Neck Surgery, USA
Brain Res 1341:3-11. 2010....
Patient perceptions of voice therapy adherenceEva Van Leer
Department of Surgery, Division of Otolaryngology, University of Wisconsin, Madison, Wisconsin 53792, USA
J Voice 24:458-69. 2010..This study yields information toward the development of scales to measure adherence-related constructs and strategies to improve treatment adherence in voice therapy...
Dopaminergic influence on rat tongue function and limb movement initiationMICHELLE RENEE CIUCCI
Division of Otolaryngology, Department of Surgery, University of Wisconsin, 600 Highland Avenue K4 709, Madison, WI 53792, USA
Exp Brain Res 194:587-96. 2009..Elucidating the relationships between the cranial and limb sensorimotor systems in the context of altered dopamine synaptic transmission may assist in developing therapies for conditions such as Parkinson's disease...
Transtheoretical model of health behavior change applied to voice therapyEva Van Leer
Department of Surgery Otolaryngology, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
J Voice 22:688-98. 2008..Principles of health behavior change can aid speech pathologists in such understanding and estimating readiness for voice therapy...
Bridging gaps in multidisciplinary head and neck cancer care: nursing coordination and case managementPeggy A Wiederholt
University of Wisconsin Paul P Carbone Comprehensive Cancer Center, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
Int J Radiat Oncol Biol Phys 69:S88-91. 2007....
Parotidectomy: ten-year review of 237 cases at a single institutionDavid C Upton
Department of Surgery, Division of Otolaryngology, University of Wisconsin Hospital and Clinics, Madison, WI 53792, USA
Otolaryngol Head Neck Surg 136:788-92. 2007....
Comparing a mechanical device with medicinal leeches for treating venous congestionGregory K Hartig
University of Wisconsin Madison Medical School, Department of Surgery, Division of Otolaryngology, K4 720 Clinical Science Center, 600 Highland Ave, Madison, WI 53792, USA
Otolaryngol Head Neck Surg 129:556-64. 2003..To compare mechanical device therapy to medicinal leech therapy for treating venous congestion...
Evaluation of performance characteristics of the medicinal leech (Hirudo medicinalis) for the treatment of venous congestionMichael L Conforti
Department of Veterans Affairs, Department of Research, VA Hospital, Madison, WI, USA
Plast Reconstr Surg 109:228-35. 2002..This study provides a realistic and quantitative estimate of the spatial and volumetric characteristics of leech feeding and passive bleeding using a clinically relevant model of acute, severe congestion...
Endolymphatic sac decompression as a treatment for Meniere's diseaseWilliam F Durland
Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin, 600 Highland Avenue, Madison, WI 53792, U S A
Laryngoscope 115:1454-7. 2005..To further assess effectiveness of endolymphatic sac decompression, we performed a prospective study to examine both symptom-specific and general health outcomes...
Augmented blood removal after medicinal leech feeding in congested tissue flapsNadine P Connor
William S. Middleton Memorial Veterans Hospital, Madison, WI, USA
J Rehabil Res Dev 39:505-12. 2002..These results are an encouraging first step toward development of a mechanical device that completely replaces the use of medicinal leeches in modern medicine...
Effect of aging on tongue protrusion forces in ratsHiromi Nagai
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin, Madison, Wisconsin 53792, USA
Dysphagia 23:116-21. 2008..The reduction of tetanus force may parallel findings in human subjects relative to isometric tongue force generation and may be associated with age-related disorders of swallowing...
Alterations in contractile properties of tongue muscles in old ratsFumikazu Ota
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin, Madison, Wisconsin, USA
Ann Otol Rhinol Laryngol 114:799-803. 2005....
Cutaneous tissue flap viability following partial venous obstructionJohn A Russell
William S. Middleton Memorial Veterans Hospital and the Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin, Madison, USA
Plast Reconstr Surg 117:2259-66; discussion 2267-8. 2006..Accordingly, subtle color change could indicate partial venous congestion and may warrant intervention by the surgeon...
The effects of aging on hypoglossal motoneurons in ratsEmilie C Schwarz
Department of Comparative Biosciences, University of Wisconsin Madison, Madison, WI 53706, USA
Dysphagia 24:40-8. 2009..Loss of primary dendrites could reduce the number of synaptic inputs and thereby impair function...
Comparison of resorbable poly-L-lactic acid-polyglycolic acid and internal Palmaz stents for the surgical correction of severe tracheomalaciaGregory K Sewall
Department of Surgery, University of Wisconsin, Madison, Wisconsin, USA
Ann Otol Rhinol Laryngol 112:515-21. 2003..In conclusion, superior efficacy of external, resorbable PLPG stents was found relative to internal Palmaz stents for the surgical repair of severe TM...
Association of extraesophageal reflux disease and sinonasal symptoms: prevalence and impact on quality of lifeThomas R Pasic
Division of Otolaryngology Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7375, USA
Laryngoscope 117:2218-28. 2007....
Age-related alterations in myosin heavy chain isoforms in rat intrinsic laryngeal musclesTatsutoshi Suzuki
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin, Madison, USA
Ann Otol Rhinol Laryngol 111:962-7. 2002..These findings suggest that aging may affect laryngeal adductory function by altering muscle fiber type composition to a slower-contracting isoform, in a manner similar to that observed with denervation...
Development of a mechanical device to replace medicinal leech (Hirudo medicinalis) for treatment of venous congestionMichael L Conforti
William S. Middleton VA Hospital, Department of Research, 2500 Overlook Terrace, Madison, WI 53705, USA
J Rehabil Res Dev 39:497-504. 2002..Thus, a mechanical device can potentially replace the use of leeches for treating venous congestion...
Testing a device to replace the leech for treating venous congestionGregory K Hartig
Division of Otolaryngology, Department of Surgery, University of Wisconsin-Madison Medical School, K4/723 Clinical Science Center, 600 Highland Ave, Madison, WI 53792, USA
Arch Facial Plast Surg 5:70-7. 2003..Mean blood volume removed was 29.5 mL/h. CONCLUSION: The device was effective in decongesting a large area of tissue during 15 hours of complete outflow obstruction, based on quantitative measurements of tissue health and viability...
Biochemistry of anterior, medial, and posterior genioglossus muscle in the ratLana M Volz
Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 7375, USA
Dysphagia 22:210-4. 2007....
Remodeling of neuromuscular junctions in aged rat genioglossus muscleSarah H Hodges
Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin, Madison, USA
Ann Otol Rhinol Laryngol 113:175-9. 2004..These results suggest that NMJ remodeling is found in aged GG muscles and may underlie the progressive neuromuscular changes observed in the elderly...
Laryngeal-respiratory kinematics are impaired in aged ratsTatsutoshi Suzuki
Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin Medical School, Madison, USA
Ann Otol Rhinol Laryngol 111:684-9. 2002..Because of the serious and pervasive nature of dysphagia and communicative impairments in the elderly, research that specifically examines the manifestations and causes of these impairments is of great importance...
Effect of aging on blood flow in rat larynxJohn A Russell
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin, Madison, WI 53792 7375, USA
Laryngoscope 118:559-63. 2008..We tested the hypothesis that there would be increased capillary red blood cell (RBC) velocity and a reduction of capillary density in the thyroarytenoid (TA) muscle of senescent rats...
Discoordination of laryngeal and respiratory movements in aged ratsHiromi Nagai
Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of Wisconsin, Madison, WI 53792-7375, USA
Am J Otolaryngol 26:377-82. 2005..Discoordination of laryngeal and respiratory motor actions associated with aging may be caused by a generalized decline in sensorimotor cranial functions and may contribute to age-related swallowing and communication impairment...
Surgical treatment of dysphagiaLiat Shama
Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792 7373, USA
Phys Med Rehabil Clin N Am 19:817-35, ix. 2008..This article includes a general overview of the causes of dysphagia that can be addressed successfully with surgery as well as a discussion of why surgery may be less appropriate for other conditions associated with dysphagia...
Iontophoretic delivery of nitric oxide donor improves local skin flap viabilityJohn A Russell
Department of Surgery, Division of Otolaryngology Head and Neck Surgery, University of Wisconsin, Madison, WI, USA
J Rehabil Res Dev 47:61-6. 2010..The results of this study suggest that NO may serve as a postoperative treatment of skin flaps to encourage skin flap survival and prevent distal necrosis...
Effect of topical mitomycin on skin wound contractionGregory K Sewall
Division of Otolaryngology, Department of Surgery, University of Wisconsin Medical School, Madison, USA
Arch Facial Plast Surg 5:59-62. 2003..CONCLUSION: Application of mitomycin, at the lowest dose and frequency of application used in this study, resulted in improved outcomes with regard to contraction of full-thickness skin wounds...
Neuromuscular junction changes in aged rat thyroarytenoid muscleNadine P Connor
Department of Surgery, University of Wisconsin, Madison 53792-7375, USA
Ann Otol Rhinol Laryngol 111:579-86. 2002..The results of this study increase our understanding of the age-related morphological changes in the larynx, and may serve as a baseline to test the effectiveness of future interventions...
Therapeutic potential of growth factors for aging voiceShigeru Hirano
From the Department of Bronchoesophagology, Kyoto National Hospital, Kyoto, Japan
Laryngoscope 114:2161-7. 2004..CONCLUSION: The present results suggest that growth factors, especially basic fibroblast growth factor, may have therapeutic potential in restoration of aged vocal fold...
Research Grants
- Exercise as a Treatment for Tongue Weakness in Aged RatsNadine Connor; Fiscal Year: 2003..Further, this work will be highly significant in discovering a neuromuscular basis for the putative benefits of exercise in the prevention and treatment of age-related swallowing impairment. ..
- Aging, Exercise and Mechanisms of Altered Tongue FunctionNADINE PATTAKOS CONNOR; Fiscal Year: 2011..Further, this work is highly significant in providing a basis for understanding mechanisms underlying the putative benefits of exercise as a therapeutic intervention for age-related changes in cranial muscles. ..
- Exercise as a Treatment for Tongue Weakness NADINE PATTAKOS CONNOR; Fiscal Year: 2010..We will determine if changes in these variables are related to changes in swallowing behaviors in aged rats. ..
- Aging, Exercise and Mechanisms of Altered Tongue FunctionNadine Connor; Fiscal Year: 2009..Further, this work is highly significant in providing a basis for understanding mechanisms underlying the putative benefits of exercise as a therapeutic intervention for age-related changes in cranial muscles. ..
- Aging, Exercise and Mechanisms of Altered Tongue FunctionNadine Connor; Fiscal Year: 2007..Further, this work is highly significant in providing a basis for understanding mechanisms underlying the putative benefits of exercise as a therapeutic intervention for age-related changes in cranial muscles. ..
- Exercise as a Treatment for Tongue Weakness in Aged RatsNadine Connor; Fiscal Year: 2007..Further, this work will be highly significant in discovering a neuromuscular basis for the putative benefits of exercise in the prevention and treatment of age-related swallowing impairment. ..
- Exercise as a Treatment for Tongue Weakness in Aged RatsNadine Connor; Fiscal Year: 2006..Further, this work will be highly significant in discovering a neuromuscular basis for the putative benefits of exercise in the prevention and treatment of age-related swallowing impairment. ..
