A Conley

Summary

Affiliation: University of California
Country: USA

Publications

  1. Conley A, Scholtz E, Legacki E, Corbin C, Knych H, Dujovne G, et al. 5?-dihydroprogesterone concentrations and synthesis in non-pregnant mares. J Endocrinol. 2018;238:25-32 pubmed publisher
    ..The presence of DHP in pregnant perissodactyla as well as proboscidean species suggests horses may be a valuable model for reproductive endocrinology in other exotic taxa. ..
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    Conley A, Pattison J, Bird I. Variations in adrenal androgen production among (nonhuman) primates. Semin Reprod Med. 2004;22:311-26 pubmed
    ..Based on the very limited available data, the most promising nonhuman primate models are marmosets for the human FZ, chimpanzees for human adrenarche, and macaques and baboons for mature ZR function that declines with senescence. ..
  3. Conley A, Moeller B, Nguyen A, Stanley S, Plant T, Abbott D. Defining adrenarche in the rhesus macaque (Macaca mulatta), a non-human primate model for adrenal androgen secretion. Mol Cell Endocrinol. 2011;336:110-6 pubmed publisher
    ..Adrenarche in any species should be defined only after careful longitudinal hormone analysis have been conducted in stages of development that are suggested by morphological and biochemical evidence of ZR maturation. ..
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    Conley A, Mapes S, Corbin C, Greger D, Walters K, Trant J, et al. A comparative approach to structure-function studies of mammalian aromatases. J Steroid Biochem Mol Biol. 2001;79:289-97 pubmed
    ..These studies are currently in progress. ..
  5. Conley A, Bernstein R, Nguyen A. Adrenarche in nonhuman primates: the evidence for it and the need to redefine it. J Endocrinol. 2012;214:121-31 pubmed publisher
  6. Conley A. Review of the reproductive endocrinology of the pregnant and parturient mare. Theriogenology. 2016;86:355-65 pubmed publisher
    ..However, all major pregnanes decrease from 3 days before foaling, when fetal cortisol is reportedly rising. Though unique, equine pregnancy and parturition share many features in common with those seen in human pregnancy and birth. ..
  7. Corbin C, Legacki E, Ball B, Scoggin K, Stanley S, Conley A. Equine 5?-reductase activity and expression in epididymis. J Endocrinol. 2016;231:23-33 pubmed publisher
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    Conley A, Hinshelwood M. Mammalian aromatases. Reproduction. 2001;121:685-95 pubmed
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    Conley A, Corbin C, Browne P, Mapes S, Place N, Hughes A, et al. Placental expression and molecular characterization of aromatase cytochrome P450 in the spotted hyena (Crocuta crocuta). Placenta. 2007;28:668-75 pubmed
    ..Other hyaenids and carnivores must be investigated to determine the morphological and functional ancestral state of their placentas, as it relates to evolutionary relationships among species in this important taxonomic group...

More Information

Publications13

  1. Legacki E, Corbin C, Ball B, Wynn M, Loux S, Stanley S, et al. Progestin withdrawal at parturition in the mare. Reproduction. 2016;152:323-31 pubmed publisher
    ..The authors conclude that progestin withdrawal associated with parturition in mares involves cessation of pregnane synthesis by the placenta. ..
  2. Legacki E, Ball B, Corbin C, Loux S, Scoggin K, Stanley S, et al. Equine fetal adrenal, gonadal and placental steroidogenesis. Reproduction. 2017;154:445-454 pubmed publisher
  3. Legacki E, Corbin C, Ball B, Scoggin K, Stanley S, Conley A. Steroidogenic enzyme activities in the pre- and post-parturient equine placenta. Reproduction. 2018;155:51-59 pubmed publisher
    ..Declining pre-partum 5α-reduced pregnane concentrations coincide with selective loss of placental 5α-reductase activity and expression at parturition in horses. ..
  4. Conley A, Scholtz E, Dujovne G, Cotterman R, Legacki E, Uliani R, et al. Inhibin-A and inhibin-B in cyclic and pregnant mares, and mares with granulosa-theca cell tumors: Physiological and diagnostic implications. Theriogenology. 2018;108:192-200 pubmed publisher
    ..01), inhibin-A concentrations were not. While both inhibin-A and -B concentrations track physiological events such as cyclic follicular activity, only inhibin-B concentrations effectively signal ovarian neoplasia in mares. ..