- Effect of aging on the microglial response to peripheral nerve injuryJessica R Conde
Department of Neuroscience, University of Florida College of Medicine, McKnight Brain Institute, P O Box 100244, Gainesville, FL 32610 0244, USA
Neurobiol Aging 27:1451-61. 2006..We propose that aging-related changes in morphology in conjunction with a less regulated proliferative response in the aged facial nucleus may be a reflection of microglial senescence...
- Microglia in the aging brainJessica R Conde
Department of Neuroscience, University of Florida College of Medicine, Gainesville, 32610, USA
J Neuropathol Exp Neurol 65:199-203. 2006..The concept of microglial senescence offers a novel perspective on aging-related neurodegeneration, namely that neurodegeneration could also occur secondary to microglial degeneration...
- Role of microglia in the central nervous system's immune responseWolfgang J Streit
Department of Neuroscience, University of Florida College of Medicine and McKnight Brain Institute, Gainesville, FL 32610, USA
Neurol Res 27:685-91. 2005..In addition, we provide an overview of the neuroinflammation associated with primary brain tumors and how microglial tumor cytotoxicity could be targeted for immunotherapeutic approaches designed to treat these lesions...