Patrick J Concannon

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi Variants in the ATM gene associated with a reduced risk of contralateral breast cancer
    Patrick Concannon
    Department of Biochemistry and Molecular Genetics and Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908 0733, USA
    Cancer Res 68:6486-91. 2008
  2. ncbi Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium
    Patrick Concannon
    Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 58:1018-22. 2009
  3. ncbi A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3
    Patrick Concannon
    Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 57:2858-61. 2008
  4. ncbi Recent progress in the genetics of diabetes
    Stephen S Rich
    Department of Public Health Sciences and Medicine, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
    Horm Res 71:17-23. 2009

Research Grants

  1. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2010
  2. Isolation of Genes for Radiation Sensitivity
    Patrick Concannon; Fiscal Year: 2005
  3. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2003
  4. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2007
  5. Isolation of Genes for Radiation Sensitivity
    Patrick Concannon; Fiscal Year: 2010
  6. Expression and proteomic characterization of risk loci in type 1 diabetes
    Patrick Concannon; Fiscal Year: 2009
  7. ATM mutations in breas cancer - a functional approach
    Patrick Concannon; Fiscal Year: 2007
  8. Isolation of Genes for Radiation Sensitivity
    Patrick Concannon; Fiscal Year: 2007
  9. ATM mutations in breast cancer - a functional approach
    Patrick Concannon; Fiscal Year: 2007
  10. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2001

Detail Information

Publications4

  1. ncbi Variants in the ATM gene associated with a reduced risk of contralateral breast cancer
    Patrick Concannon
    Department of Biochemistry and Molecular Genetics and Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia 22908 0733, USA
    Cancer Res 68:6486-91. 2008
    ..1-0.6; c.6348-54T>C RR, 0.2; 95% CI, 0.1-0.8]. These data suggest that some alleles of ATM may exert an antineoplastic effect, perhaps by altering the activity of ATM as an initiator of DNA damage responses or a regulator of p53...
  2. ncbi Genome-wide scan for linkage to type 1 diabetes in 2,496 multiplex families from the Type 1 Diabetes Genetics Consortium
    Patrick Concannon
    Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 58:1018-22. 2009
    ..However, such studies have limited power to detect genes containing multiple rare variants that contribute significantly to disease risk...
  3. ncbi A human type 1 diabetes susceptibility locus maps to chromosome 21q22.3
    Patrick Concannon
    Department of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville, Virginia, USA
    Diabetes 57:2858-61. 2008
    ..In the current study, we tested for evidence of loci associated with type 1 diabetes utilizing genome-wide linkage scan data and family-based association methods...
  4. ncbi Recent progress in the genetics of diabetes
    Stephen S Rich
    Department of Public Health Sciences and Medicine, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
    Horm Res 71:17-23. 2009
    ..Nonetheless, detection of diabetes susceptibility genes may facilitate identification of novel pathways that can serve as therapeutic targets and lead to disease prevention...

Research Grants44

  1. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2010
    ..The proposed studies in this application will characterize newly discovered genetic risk loci for T1D which may serve as useful biomarkers for prediction of disease or as targets for therapy. ..
  2. Isolation of Genes for Radiation Sensitivity
    Patrick Concannon; Fiscal Year: 2005
    ..abstract_text> ..
  3. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2003
    ..abstract_text> ..
  4. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2007
    ..Our long-term goal is to define the genetic contributions to T1D pathogenesis and use this information to develop novel tools for prediction and prevention of T1D. ..
  5. Isolation of Genes for Radiation Sensitivity
    Patrick Concannon; Fiscal Year: 2010
    ....
  6. Expression and proteomic characterization of risk loci in type 1 diabetes
    Patrick Concannon; Fiscal Year: 2009
    ..The proposed studies in this application will characterize newly discovered genetic risk loci for T1D which may serve as useful biomarkers for prediction of disease or as targets for therapy. ..
  7. ATM mutations in breas cancer - a functional approach
    Patrick Concannon; Fiscal Year: 2007
    ..abstract_text> ..
  8. Isolation of Genes for Radiation Sensitivity
    Patrick Concannon; Fiscal Year: 2007
    ....
  9. ATM mutations in breast cancer - a functional approach
    Patrick Concannon; Fiscal Year: 2007
    ..abstract_text> ..
  10. SUSCEPTIBILITY GENES IN TYPE 1 DIABETES
    Patrick Concannon; Fiscal Year: 2001
    ..abstract_text> ..
  11. ISOLATION OF THE GENE(S) FOR ATAXIA-TELANGIECTASIA
    Patrick Concannon; Fiscal Year: 2000
    ..Thus, identification of the NBS gene may shed further light on the function of ATM as well as providing additional insight into the pathways and components of cellular responses to radiation, in general. ..
  12. SUSCEPTIBILITY GENES IN TYPE I DIABETES
    Patrick Concannon; Fiscal Year: 1993
    ..While any one of these laboratories could carry out the proposed experiments independently, this collaboration should greatly speed the rate at which our goal of mapping IDDM susceptibility genes in the human can be achieved...
  13. ISOLATION OF THE GENE(S) FOR ATAXIA TELANGIECTASIA
    Patrick Concannon; Fiscal Year: 1993
    ....