Research Topics
Genomes and GenesSpecies | Peggy A ComptonSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Hyperalgesia in heroin dependent patients and the effects of opioid substitution therapyPeggy Compton
School of Nursing, University of California, Los Angeles, CA 90095 6918, USA
J Pain 13:401-9. 2012..Hyperalgesia is present with illicit and treatment opioid use, and does not appear to appreciably improve over the course of treatment...
Gabapentin improves cold-pressor pain responses in methadone-maintained patientsPeggy Compton
School of Nursing, University of California, Los Angeles, CA 90095, United States
Drug Alcohol Depend 109:213-9. 2010..These results support that GPN, as prescribed for the treatment of neuropathic pain, is effective in decreasing OIH in patients who are abstinent and stable in methadone treatment...
Introduction of a self-report version of the Prescription Drug Use Questionnaire and relationship to medication agreement noncompliancePeggy A Compton
Acute Care Section, School of Nursing at UCLA, Los Angeles, California 90095 6918, USA
J Pain Symptom Manage 36:383-95. 2008..This study supports the PDUQp as a useful tool for assessing and predicting problematic opioid medication use in a chronic pain patient sample...
Lack of effect of chronic dextromethorphan on experimental pain tolerance in methadone-maintained patientsPeggy A Compton
Acute Care Section, School of Nursing, University of California at Los Angeles, Factor Building 4 246, Box 956918, Los Angeles, CA 90095 6918, USA
Addict Biol 13:393-402. 2008..These results support that chronic high-dose NMDA antagonism does not improve tolerance for pain in MM patients, although a gender effect on DEX response is suggested...
The role of urine toxicology in chronic opioid analgesic therapyPeggy Compton
University of California Los Angeles School of Nursing, Los Angeles, California 90095, USA
Pain Manag Nurs 8:166-72. 2007....
Perceptual reactance, drug preference, and electrodermal activity in treatment-seeking substance abusersP Compton
UCLA School of Nursing, Acute Care Section 90095 6918, USA
Issues Ment Health Nurs 21:109-25. 2000..The study hypothesis was only supported in the electrodermally-responsive group...
Pharmacokinetics, bioavailability and opioid effects of liquid versus tablet buprenorphinePeggy Compton
School of Nursing, University of California at Los Angeles, Factor Building 4 246, Box 956918, Los Angeles, CA 90095 6918, USA
Drug Alcohol Depend 82:25-31. 2006....
Precipitated opioid withdrawal across acute physical dependence induction methodsPeggy Compton
School of Nursing, University of California at Los Angeles, Los Angeles, CA 90266, USA
Pharmacol Biochem Behav 77:263-8. 2004..Thus, despite altering the pretreatment opioid and route of administration, all three APD protocols produced similar and reliable withdrawal symptoms in humans...
Withdrawal hyperalgesia after acute opioid physical dependence in nonaddicted humans: a preliminary studyPeggy Compton
School of Nursing, University of California at Los Angeles, Los Angeles, California 90095 6918, USA
J Pain 4:511-9. 2003....
Pain intolerance in opioid-maintained former opiate addicts: effect of long-acting maintenance agentP Compton
School of Nursing, University of California at Los Angeles UCLA, Factor Building 4 246, Box 956918, Los Angeles, CA 90095 6918, USA
Drug Alcohol Depend 63:139-46. 2001..Diminished pain tolerance in patients receiving opioid maintenance treatment has significant clinical implications. More research is needed to determine if buprenorphine offers advantages over methadone in this regard...
Association between human mu-opioid receptor gene polymorphism, pain tolerance, and opioid addictionPeggy Compton
Acute Care Section, UCLA School of Nursing, Los Angeles, California 90095 6918, USA
Am J Med Genet B Neuropsychiatr Genet 121:76-82. 2003....
Effect of oral ketorolac and gender on human cold pressor pain tolerancePeggy Compton
School of Nursing, University of California at Los Angeles, Los Angeles, California, USA
Clin Exp Pharmacol Physiol 30:759-63. 2003....
Chronic pain, substance abuse and addictionPeggy Compton
School of Nursing, University of California at Los Angeles, Factor Building 4 246, Box 956918, Los Angeles, CA 90095 6918, USA
Nurs Clin North Am 38:525-37. 2003..If addiction is treated as a known risk when providing opioid analgesia to a recovering addict, its development can be minimized while pain relief is provided...
Pain-related activation of leukocyte cellular adhesion molecules: preliminary findingsCharles A Griffis
School of Nursing, University of California at Los Angeles, Los Angeles, CA 90095 1702, USA
Neuroimmunomodulation 14:224-8. 2007..This study examined the effects of acute experimental pain on catecholamine and cortisol levels and leukocyte expression of cellular adhesion molecules...
Correlates of hospitalization for alcohol-using methadone-maintained persons with physical health problemsAdeline Nyamathi
University of California, Los Angeles, CA, USA
West J Nurs Res 31:525-43. 2009..Identification of hospitalization risk factors among alcohol-abusing MMT clients is a first step to developing risk-reducing interventions designed to lower hospitalization rates in this population...
The effect of pain on leukocyte cellular adhesion moleculesCharles A Griffis
Department of Anesthesiology, School of Nursing, University of California, Los Angeles 90095, USA
Biol Res Nurs 7:297-312. 2006..Clinical implications and suggestions for further research in the area of painful stress-related inflammation are offered...
The addiction behaviors checklist: validation of a new clinician-based measure of inappropriate opioid use in chronic painStephen M Wu
Greater Los Angeles Veterans Affairs Healthcare System, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
J Pain Symptom Manage 32:342-51. 2006..The psychometric findings support the ABC as a viable assessment tool that can increase a provider's confidence in determinations of appropriate vs. inappropriate opioid use...
Caring for an alcohol-dependent patientPeggy Compton
Acute Care Section, University of California Los Angeles School of Nursing, USA
Nursing 32:58-63; quiz N242. 2002
Research Grants
- Hyperalgesia in Methadone Patients: Can it be Treated?Margaret Compton; Fiscal Year: 2007..abstract_text> ..
