Ricki J Colman

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Skeletal effects of long-term caloric restriction in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Age (Dordr) 34:1133-43. 2012
  2. ncbi request reprint Muscle mass loss in Rhesus monkeys: age of onset
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, 53715, USA
    Exp Gerontol 40:573-81. 2005
  3. pmc Caloric restriction delays disease onset and mortality in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Science 325:201-4. 2009
  4. pmc Attenuation of sarcopenia by dietary restriction in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin Madison, 1220 Capitol Ct, Madison, WI 53715, USA
    J Gerontol A Biol Sci Med Sci 63:556-9. 2008
  5. pmc Nonhuman primate calorie restriction
    Ricki J Colman
    Wisconsin National Primate Research Center, SMPH, University of Wisconsin, Madison, Wisconsin 53715, USA
    Antioxid Redox Signal 14:229-39. 2011
  6. pmc A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys
    Erik K Kastman
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
    J Neurosci 32:11897-904. 2012
  7. pmc Calorie restriction reduces psychological stress reactivity and its association with brain volume and microstructure in aged rhesus monkeys
    Auriel A Willette
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
    Psychoneuroendocrinology 37:903-16. 2012
  8. pmc Homocysteine, neural atrophy, and the effect of caloric restriction in rhesus monkeys
    Auriel A Willette
    Harlow Primate Laboratory, Department of Psychology, University of Wisconsin Madison, Madison, WI, USA
    Neurobiol Aging 33:670-80. 2012
  9. pmc Calorie restriction reduces the influence of glucoregulatory dysfunction on regional brain volume in aged rhesus monkeys
    Auriel A Willette
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA
    Diabetes 61:1036-42. 2012
  10. pmc Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys
    Susan H McKiernan
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, United States
    Exp Gerontol 47:229-36. 2012

Collaborators

Detail Information

Publications36

  1. pmc Skeletal effects of long-term caloric restriction in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Age (Dordr) 34:1133-43. 2012
    ..Circulating serum markers of bone turnover were not different between C and R with nonsignficant diet-by-time interactions. We believe the lower bone mass in R animals reflects the smaller body size and not pathological osteopenia...
  2. ncbi request reprint Muscle mass loss in Rhesus monkeys: age of onset
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, 53715, USA
    Exp Gerontol 40:573-81. 2005
    ..5 years of age. Furthermore, our data indicate percentage declines in ESM similar to those seen in humans with advancing age. These data support the suitability of the Rhesus monkey as a primate sarcopenia model...
  3. pmc Caloric restriction delays disease onset and mortality in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Science 325:201-4. 2009
    ..Furthermore, CR delayed the onset of age-associated pathologies. Specifically, CR reduced the incidence of diabetes, cancer, cardiovascular disease, and brain atrophy. These data demonstrate that CR slows aging in a primate species...
  4. pmc Attenuation of sarcopenia by dietary restriction in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin Madison, 1220 Capitol Ct, Madison, WI 53715, USA
    J Gerontol A Biol Sci Med Sci 63:556-9. 2008
    ..Body weight-adjusted skeletal muscle mass declined somewhat in both groups but was far more rapid in the control group. We have shown that moderate, adult-onset DR can attenuate sarcopenia in a nonhuman primate model...
  5. pmc Nonhuman primate calorie restriction
    Ricki J Colman
    Wisconsin National Primate Research Center, SMPH, University of Wisconsin, Madison, Wisconsin 53715, USA
    Antioxid Redox Signal 14:229-39. 2011
    ..Finally, we highlight the importance of primate studies in the context of aging research and its potential to advance our understanding of human aging and health...
  6. pmc A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys
    Erik K Kastman
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
    J Neurosci 32:11897-904. 2012
    ..Our observations suggest that the CR-induced benefit of reduced iron deposition and preserved motor function may indicate neural protection similar to effects described previously in aging rodent and primate species...
  7. pmc Calorie restriction reduces psychological stress reactivity and its association with brain volume and microstructure in aged rhesus monkeys
    Auriel A Willette
    Geriatric Research Education and Clinical Center, Wm S Middleton Memorial Veterans Hospital, Madison, WI 53705, USA
    Psychoneuroendocrinology 37:903-16. 2012
    ..Dietary interventions, such as calorie restriction (CR), affect stress biology and may moderate the pathogenic relationship between stress reactivity and brain in limbic and prefrontal regions...
  8. pmc Homocysteine, neural atrophy, and the effect of caloric restriction in rhesus monkeys
    Auriel A Willette
    Harlow Primate Laboratory, Department of Psychology, University of Wisconsin Madison, Madison, WI, USA
    Neurobiol Aging 33:670-80. 2012
    ..The data suggest that CR may ameliorate the influence of Hcy on several important age-related parameters of parenchymal health...
  9. pmc Calorie restriction reduces the influence of glucoregulatory dysfunction on regional brain volume in aged rhesus monkeys
    Auriel A Willette
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin, USA
    Diabetes 61:1036-42. 2012
    ..These results suggest that CR improves glucose regulation and may positively influence specific brain regions and at least motor task performance. Additional studies are warranted to validate these relationships...
  10. pmc Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys
    Susan H McKiernan
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, United States
    Exp Gerontol 47:229-36. 2012
    ..We suggest that muscle fibers from CR animals are better poised to endure and adapt to changes in muscle mass than those of Control animals...
  11. ncbi request reprint Insulin resistance and impaired insulin secretion in prenatally androgenized male rhesus monkeys
    Cristin M Bruns
    Department of Medicine, University of Wisconsin, Madison, Wisconsin 53792, USA
    J Clin Endocrinol Metab 89:6218-23. 2004
    ..52, 711.89); P < 0.02]. PA males do not exhibit elevated androgens during adulthood, suggesting that insulin resistance and impaired pancreatic beta-cell function may result from fetal reprogramming of key metabolic tissues...
  12. ncbi request reprint Influences of calorie restriction and age on energy expenditure in the rhesus monkey
    Aarthi Raman
    Nutritional Sciences, Univ of Wisconsin Madison, 1415 Linden Dr, Madison, WI 53607, USA
    Am J Physiol Endocrinol Metab 292:E101-6. 2007
    ..077). Night EE did not differ between calorie-restricted and C younger monkeys after adjusting for FFM and FM. In conclusion, CR did not alter the age-related decrease in EE with CR...
  13. ncbi request reprint Dietary restriction and beta-cell sensitivity to glucose in adult male rhesus monkeys
    Theresa A Gresl
    Wisconsin National Primate Research Center and Department of Biostatistics and Medical Informatics, University of Wisconsin Madison, 53715, USA
    J Gerontol A Biol Sci Med Sci 58:598-610. 2003
    ..Enhanced peripheral insulin sensitivity among R monkeys was strongly correlated with lower Ø(b)...
  14. pmc A shift in energy metabolism anticipates the onset of sarcopenia in rhesus monkeys
    Thomas D Pugh
    Department of Medicine, University of Wisconsin, Madison, WI 53706, USA
    Aging Cell 12:672-81. 2013
    ..We suggest that changes in energy metabolism contribute directly to skeletal muscle aging in rhesus monkeys...
  15. pmc Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study
    Aadhavi Sridharan
    Medical Scientist Training Program, University of Wisconsin Madison, 750 Highland Ave, Madison, WI 53705, USA
    Brain Res 1508:1-8. 2013
    ..The present study is a preliminary post-mortem histological analysis of the effects of CR on brain health, and further studies using molecular and biochemical techniques are warranted to elucidate underlying mechanisms...
  16. ncbi request reprint Reference body composition in adult rhesus monkeys: glucoregulatory and anthropometric indices
    Aarthi Raman
    Department of Nutritional Sciences, University of Wisconsin Madison, Madison, WI 53706, USA
    J Gerontol A Biol Sci Med Sci 60:1518-24. 2005
    ..The estimated reference range for %BF was 9%-23% in male and 8%-18% in female monkeys, corresponding to body mass indices of 32-44 kg/m(2) for male and 27-35 kg/m(2) for female monkeys...
  17. pmc Effects of caloric restriction on cardiovascular aging in non-human primates and humans
    Christina Cruzen
    Wisconsin National Primate Research Center, University of Wisconsin Madison, 1220 Capitol Court, Madison, WI 53715, USA
    Clin Geriatr Med 25:733-43, ix-x. 2009
    ..This article reviews evidence that CR in nonhuman primates and people has a positive effect on risk factors for CVD...
  18. pmc Metabolizable energy intake during long-term calorie restriction in rhesus monkeys
    Aarthi Raman
    Department of Nutritional Sciences, University of Wisconsin, Madison, WI 53706, USA
    Exp Gerontol 42:988-94. 2007
    ..Use of diet weight is a reasonable estimate of the level of CR when food waste is assessed...
  19. pmc Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle
    Susan H McKiernan
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, United States
    Exp Gerontol 46:23-9. 2011
    ..CR did not prevent stochastic mitochondrial deletion mutations in muscle fibers but CR may have contributed to the maintenance of affected fibers...
  20. pmc Brain volumetric and microstructural correlates of executive and motor performance in aged rhesus monkeys
    Aadhavi Sridharan
    Neuroscience Training Program, University of Wisconsin Madison Madison, WI, USA Medical Scientist Training Program, University of Wisconsin Madison Madison, WI, USA
    Front Aging Neurosci 4:31. 2012
    ..Finally, these brain-behavior correlations for the motor task were attenuated in CR animals compared to controls, indicating a potential protective effect of the dietary intervention...
  21. pmc Early-to-mid gestation fetal testosterone increases right hand 2D:4D finger length ratio in polycystic ovary syndrome-like monkeys
    Andrew D Abbott
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, United States of America
    PLoS ONE 7:e42372. 2012
    ..As variation in timing and duration of gestational T exposure alter male-like dimensions of RH2D independently of RH4D, postnatal RH2D:4D provides a complex biomarker for fetal T exposure...
  22. ncbi request reprint Energy restriction-induced changes in body composition are age specific in mice
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    J Nutr 137:2247-51. 2007
    ..Our data refute the hypothesis that ER causes a unique change in body composition that is conserved across age and suggest that fat loss may not be an essential component of the anti-aging effects of ER...
  23. ncbi request reprint Insulin sensitivity and glucose effectiveness from three minimal models: effects of energy restriction and body fat in adult male rhesus monkeys
    Theresa A Gresl
    Wisconsin Primate Research Center, 1220 Capitol Court, Madison, WI 53715, USA
    Am J Physiol Regul Integr Comp Physiol 285:R1340-54. 2003
    ..The observed insulin sensitivity indexes from all models, elevated among R vs. C monkeys, may be explained, at least in part, by the difference in body fat content between these groups after chronic DR...
  24. doi request reprint Caloric restriction reduces age-related and all-cause mortality in rhesus monkeys
    Ricki J Colman
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin 53715, USA
    Nat Commun 5:3557. 2014
    ..Our data indicate that the benefits of CR on ageing are conserved in primates. ..
  25. pmc Development of metabolic function biomarkers in the common marmoset, Callithrix jacchus
    Toni E Ziegler
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
    Am J Primatol 75:500-8. 2013
    ..We have performed biological validations for insulin, adiponectin, leptin, and ghrelin to demonstrate the use of these biomarkers in examining metabolic syndrome and other related diseases in the common marmoset...
  26. ncbi request reprint Increased adiposity in female rhesus monkeys exposed to androgen excess during early gestation
    Joel R Eisner
    Wisconsin Primate Research Center, Department of Obstetrics and Gynecology, Endocrinology Reproductive Physiology Program, University of Wisconsin, Madison, Wisconsin, USA
    Obes Res 11:279-86. 2003
    ..The aim of this study was to investigate the effects of early-gestational androgen excess on adult body fat distribution in female rhesus monkeys...
  27. pmc Body weight impact on puberty: effects of high-calorie diet on puberty onset in female rhesus monkeys
    Ei Terasawa
    Wisconsin National Primate Research Center, University of Wisconsin, 1223 Capitol Court, Madison, Wisconsin 53715 1299, USA
    Endocrinology 153:1696-705. 2012
    ..The findings of this study suggest the importance of close monitoring of juvenile feeding behaviors as an important intervention to reduce the prevalence of precocious development and metabolic diseases in adulthood...
  28. pmc Glucoregulatory function in adult rhesus macaques (Macaca mulatta) undergoing treatment with medroxyprogesterone acetate for endometriosis
    Christina L Cruzen
    Wisconsin National Primate Research Center, University of Wisconsin Madison, WI, USA
    J Am Assoc Lab Anim Sci 50:921-5. 2011
    ..These data suggest that glucoregulatory function should be considered when endometriosis treatment is planned for rhesus macaques...
  29. pmc α3(V) collagen is critical for glucose homeostasis in mice due to effects in pancreatic islets and peripheral tissues
    Guorui Huang
    Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin 53706, USA
    J Clin Invest 121:769-83. 2011
    ..Our results underscore the emerging view of the importance of ECM to the microenvironments that inform proper development/functioning of specialized cells, such as adipocytes, β cells, and skeletal muscle...
  30. pmc A calorie-restricted diet decreases brain iron accumulation and preserves motor performance in old rhesus monkeys
    Erik K Kastman
    Geriatric Research Education and Clinical Center, William S Middleton Memorial Veterans Hospital, Madison, Wisconsin 53705, USA
    J Neurosci 30:7940-7. 2010
    ..Our observations suggest that the CR-induced benefit of reduced iron deposition and preserved motor function may indicate neural protection similar to effects described previously in aging rodent and primate species...
  31. ncbi request reprint Aspects of common marmoset basic biology and life history important for biomedical research
    David H Abbott
    Wisconsin Primate Research Center, Department of Ob Gyn, University of Wisconsin, 1223 Capitol Court, Madison, Wisconsin 53715, USA
    Comp Med 53:339-50. 2003
    ..These differences, however, permit the use of common marmosets in unconventional research strategies targeted on human pathology...
  32. pmc Using snacks high in fat and protein to improve glucoregulatory function in adolescent male marmosets (Callithrix jacchus)
    Toni E Ziegler
    Wisconsin National Primate Research Center, University of Wisconsin, Madison, Wisconsin, USA
    J Am Assoc Lab Anim Sci 52:756-62. 2013
    ..This study also demonstrates the utility of marmosets as a model for understanding the implications of dietary fats in humans. ..
  33. pmc Sex differences in spinal osteoarthritis in humans and rhesus monkeys (Macaca mulatta)
    Andrea E Duncan
    Department of Anthropology, University of Washington, Seattle, WA 98195, USA
    Spine (Phila Pa 1976) 37:915-22. 2012
    ..Retrospective study of male and female spinal osteoarthritis, characterized by lateral spine thoracolumbar radiographs, in humans and nonhuman primates...
  34. pmc Prospects and perspectives in primate aging research
    Rozalyn M Anderson
    Department of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA
    Antioxid Redox Signal 14:203-5. 2011
    ....
  35. ncbi request reprint Progressive arthropathy in mice with a targeted disruption of the Mop3/Bmal-1 locus
    Maureen K Bunger
    McArdle Laboratory for Cancer Research, University of Wisconsin Medical School, Madison, Wisconsin 53706, USA
    Genesis 41:122-32. 2005
    ..This pathology appears to explain the decreased activity of Mop3 null mice and suggests that MOP3 is an inhibitor of ligament and tendon ossification...
  36. ncbi request reprint The influence of sex hormones on circulating nitric oxide (NOx) levels in rhesus monkeys (Macaca Mulatta)
    Omid Khorram
    Department of Obstetrics and Gynecology, University of Wisconsin, Madison, WI, USA
    Med Sci Monit 8:BR489-95. 2002
    ..In addition changes in circulating NOx during the menstrual cycle were measured...