Research Topics
Genomes and Genes | Lisa CollettiSummaryAffiliation: University of Michigan Country: USA Publications
Research Grants
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Detail Information
Publications
Proliferative effects of CXC chemokines in rat hepatocytes in vitro and in vivoL M Colletti
Department of Surgery, University of Michigan Medical School, Ann Arbor 48109, USA
Shock 10:248-57. 1998..These data suggest that the CXC chemokines may be important agents for the induction of hepatocyte proliferation and may be important molecules in vivo in the setting of liver injury, repair, and regeneration...
Stem cell factor restores hepatocyte proliferation in IL-6 knockout mice following 70% hepatectomyXiaodan Ren
Department of Surgery, University of Michigan, Medical School, Ann Arbor, Michigan 48109 0331, USA
J Clin Invest 112:1407-18. 2003..Further in vivo studies in IL-6 knockout mice demonstrate that SCF administration to these animals increases p-stat3 levels, suggesting that the SCF-induced increase in hepatocyte proliferation in this system is stat3-mediated...- Perceived obstacles to career success for women in academic surgeryL M Colletti
Department of Surgery, University of Michigan Health System, 1500 E Medical Center Dr, 2921 Taubman Center, Ann Arbor, MI 48109 0331, USA
Arch Surg 135:972-7. 2000..We reviewed published studies concerning women in academic surgery within the context of reporting the results of a survey of both male and female surgeons at 1 academic center... - The ratio of ELR+ to ELR- CXC chemokines affects the lung and liver injury following hepatic ischemia/ reperfusion in the ratL M Colletti
Department of Surgery, University of Michigan Medical School, Ann Arbor, MI, USA
Hepatology 31:435-45. 2000..This suggests that the alteration in the balance of ELR+ to ELR- CXC chemokines results in a decrease in tissue injury through a mechanism other than through an alteration in tissue neutrophil levels... - Stem cell factor and its receptor, c-kit, are important for hepatocyte proliferation in wild-type and tumor necrosis factor receptor-1 knockout mice after 70% hepatectomyXiaodan Ren
Department of Surgery, University of Michigan Medical School, Ann Arbor, Mich
Surgery 143:790-802. 2008..We now hypothesize that TNF-alpha's hepatoproliferative effects are also dependent on SCF... - Mitogenic properties of endogenous and pharmacological doses of macrophage inflammatory protein-2 after 70% hepatectomy in the mouseXiaodan Ren
Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Pathol 163:563-70. 2003..These data show that MIP-2 is important for hepatocyte proliferation after partial hepatectomy and that pharmacological MIP-2 doses after hepatic injury accelerate hepatic regeneration... 
Is the accreditation council for graduate medical education a suitable proxy for resident unions?Monica L Lypson
University of Michigan, 2500 Green Road 700, Ann Arbor, MI 48105, USA
Acad Med 84:296-300. 2009....- Preventing surgical fires: who needs to be educated?Monica L Lypson
Ambulatory Care, Ann Arbor Veterans Administration Healthcare System, Michigan, USA
Jt Comm J Qual Patient Saf 31:522-7. 2005..CONCLUSION: Surgical fires can usually be prevented by educating staff about risk and prevention strategies. Such education should be part of all undergraduate medical, nursing, and other allied health profession education... - Using OSCEs to teach WHO patient safety solutionsMonica L Lypson
University of Michigan, 2500 Green Road Suite #700, Ann Arbor, Michigan 48105, USA
Med Educ 42:523-4. 2008 - Initial use of a novel instrument to measure professionalism in surgical residentsPaul G Gauger
Department of Surgery, Division of Endocrine Surgery, 1500 E Medical Center Dr, Taubman Center TC2920H, Ann Arbor, MI 48109 0331, USA
Am J Surg 189:479-87. 2005..No universally accepted method to measure professionalism exists. We developed an instrument to measure specific aspects of professionalism in surgical residents... - Hospital teaching status and outcomes of complex surgical procedures in the United StatesJustin B Dimick
Department of Surgery, University of Michigan Medical Center, Ann Arbor, USA
Arch Surg 139:137-41. 2004..Complex operations performed in teaching hospitals have similar outcomes as those performed in nonteaching hospitals... - Attending, house officer, and medical student perceptions about teaching in the third-year medical school general surgery clerkshipSumit K De
Department of Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA
J Am Coll Surg 199:932-42. 2004..Structured direct faculty contact, definition of medical student roles on the surgical team, and more consistent feedback can be rapidly improved... - Hospital volume and surgical outcomes for elderly patients with colorectal cancer in the United StatesJustin B Dimick
Surgical Outcomes Research Team SORT, Department of Surgery, University of Michigan Medical Center, Ann Arbor, MI 48109 0329, USA
J Surg Res 114:50-6. 2003..The objective of this study was to determine the impact of hospital volume on mortality for patients of different age groups to determine whether elderly patients would derive more benefit from selective referral policies... - Issues in the recruitment and success of women in academic surgerySeema S Sonnad
Department of Surgery, University of Michigan, Ann Arbor, USA
Surgery 132:415-9. 2002.... - Matrix metalloproteinase-9 is an important factor in hepatic regeneration after partial hepatectomy in miceEric W Olle
Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109-0331, USA
Hepatology 44:540-9. 2006..In conclusion, MMP-9 plays an important role in liver regeneration after partial hepatectomy by affecting matrix remodeling, as well as cytokine, growth factor, and caspase expression... - National trends in the use and outcomes of hepatic resectionJustin B Dimick
Department of Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA
J Am Coll Surg 199:31-8. 2004..Short-term outcomes have also improved over the same time period, with more improvement seen at higher volume centers than in lower volume centers... - Presentation and treatment of venomous snakebites at a northern academic medical centerRobert A Cowles
Section of General Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Am Surg 69:445-9. 2003..There were no severe envenomations and no mortalities. On short-term follow-up all patients recovered without sequelae. This report demonstrates that venomous snakebites can be treated effectively at low-volume centers... - IL-22 is involved in liver regeneration after hepatectomyXiaodan Ren
Department of Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Physiol Gastrointest Liver Physiol 298:G74-80. 2010..In addition, animals treated with anti-IL-22 antibody also expressed less TGF-alpha. In conclusion, these data suggest that IL-22 is involved in liver regeneration and this may be due to interaction with IL-6 and TGF-alpha cascades... - Stem cell factor and c-kit are involved in hepatic recovery after acetaminophen-induced liver injury in miceBin Hu
Department of Surgery, University of Michigan, Ann Arbor, MI, USA
Am J Physiol Gastrointest Liver Physiol 295:G45-G53. 2008....
Research Grants
- CXC CHEMOKINES AND LIVER REGENERATIONLisa Colletti; Fiscal Year: 2007..To investigate this hypothesis, we will examine specific MIP-2-related mechanisms of hepatocyte proliferation and apoptosis following 70% hepatectomy, as well as IP-10's modulating effects in this system. ..
- SCF in liver repair after hepatectomy or toxic injuryLisa Colletti; Fiscal Year: 2006..These studies will help to elucidate novel mechanisms in SCF-mediated hepatocyte protection and regeneration in a clinically relevant liver resection and toxicity model. ..
- CXC CHEMOKINES AND LIVER REGENERATIONLisa Colletti; Fiscal Year: 2002..By providing insights into the hepatic regenerative process, these studies could potentially lead to novel treatments for the failing liver. ..
- CXC CHEMOKINES AND LIVER REGENERATIONLisa Colletti; Fiscal Year: 2009..To investigate this hypothesis, we will examine specific MIP-2-related mechanisms of hepatocyte proliferation and apoptosis following 70% hepatectomy, as well as IP-10's modulating effects in this system. ..