Sean Colgan

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. ncbi Adenosine and gastrointestinal inflammation
    Sean P Colgan
    Department of Medicine and Mucosal Inflammation Program, University of Colorado School of Medicine, 12700 East 19th Ave, MS B 146, Aurora, CO 80045, USA
    J Mol Med (Berl) 91:157-64. 2013
  2. ncbi Contributions of neutrophils to resolution of mucosal inflammation
    Sean P Colgan
    Department of Medicine and the Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Immunol Res 55:75-82. 2013
  3. ncbi Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery
    Sean P Colgan
    Departments of Medicine and Anesthesiology and the Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Annu Rev Physiol 74:153-75. 2012
  4. ncbi Hypoxia: an alarm signal during intestinal inflammation
    Sean P Colgan
    Division of Gastroenterology, Mucosal Inflammation Program, University of Colorado Denver, 12700 E 19th Avenue MS B146, Aurora, CO 80045, USA
    Nat Rev Gastroenterol Hepatol 7:281-7. 2010
  5. ncbi Natural killer T cells in mucosal homeostasis
    Arthur Kaser
    Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Ann N Y Acad Sci 1029:154-68. 2004
  6. ncbi CD1d-restricted T cell pathways at the epithelial-lymphocyte-luminal interface
    Arthur Kaser
    Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA 02115, USA
    J Pediatr Gastroenterol Nutr 39:S719-22. 2004
  7. ncbi Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization
    Christopher F MacManus
    Department of Medicine, University of Colorado Health Sciences Center, Aurora, Colorado, USA
    FASEB J 25:1856-64. 2011

Research Grants

  1. Neutrophils and Vascular Endothelial Permeability
    Sean Colgan; Fiscal Year: 2006
  2. Hypoxia and Inflammation at the Vascular Interface
    Sean P Colgan; Fiscal Year: 2010
  3. ROLE OF EPITHELIA IN ISCHEMIA/REPERFUSION INJURY
    Sean Colgan; Fiscal Year: 2004
  4. NEUTROPHIL-ENDOTHELIAL AND VASCULAR PERMEABILITY
    Sean Colgan; Fiscal Year: 2002
  5. Role of Epithelia In Ischemia Reperfusion Injury
    Sean P Colgan; Fiscal Year: 2010

Collaborators

Detail Information

Publications7

  1. ncbi Adenosine and gastrointestinal inflammation
    Sean P Colgan
    Department of Medicine and Mucosal Inflammation Program, University of Colorado School of Medicine, 12700 East 19th Ave, MS B 146, Aurora, CO 80045, USA
    J Mol Med (Berl) 91:157-64. 2013
    ..Here, we review contributions of Ado to cell and tissue stress responses, with a particular emphasis on the gastrointestinal mucosa...
  2. ncbi Contributions of neutrophils to resolution of mucosal inflammation
    Sean P Colgan
    Department of Medicine and the Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Immunol Res 55:75-82. 2013
    ..Here, we highlight several recent examples of how PMN coordinate the resolution of ongoing inflammation, with a particular focus on the gastrointestinal mucosa...
  3. ncbi Adenosine and hypoxia-inducible factor signaling in intestinal injury and recovery
    Sean P Colgan
    Departments of Medicine and Anesthesiology and the Mucosal Inflammation Program, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Annu Rev Physiol 74:153-75. 2012
    ..Such information has provided new insights into disease pathogenesis and, importantly, will provide insights into new therapeutic targets...
  4. ncbi Hypoxia: an alarm signal during intestinal inflammation
    Sean P Colgan
    Division of Gastroenterology, Mucosal Inflammation Program, University of Colorado Denver, 12700 E 19th Avenue MS B146, Aurora, CO 80045, USA
    Nat Rev Gastroenterol Hepatol 7:281-7. 2010
    ..We also discuss the pros and cons of targeting these pathways to treat patients with IBD...
  5. ncbi Natural killer T cells in mucosal homeostasis
    Arthur Kaser
    Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115, USA
    Ann N Y Acad Sci 1029:154-68. 2004
    ..In this review, we focus on recent observations on the characteristics of CD1d-restricted pathways in mucosal compartments, after a brief introduction into the biology of CD1d and CD1d-restricted T cells...
  6. ncbi CD1d-restricted T cell pathways at the epithelial-lymphocyte-luminal interface
    Arthur Kaser
    Division of Gastroenterology, Brigham and Women's Hospital, Boston, MA 02115, USA
    J Pediatr Gastroenterol Nutr 39:S719-22. 2004
    ..In this review, we focus on recent observations in the characteristics of CD1d-restricted pathways in mucosal compartments after a brief introduction to the biology of CD1d and CD1d-restricted T cells...
  7. ncbi Anti-inflammatory actions of adrenomedullin through fine tuning of HIF stabilization
    Christopher F MacManus
    Department of Medicine, University of Colorado Health Sciences Center, Aurora, Colorado, USA
    FASEB J 25:1856-64. 2011
    ..Taken together, these results identify ADM as an endogenously generated vascular mediator that functions as a mucosal protective factor through fine tuning of HIF activity...

Research Grants21

  1. Neutrophils and Vascular Endothelial Permeability
    Sean Colgan; Fiscal Year: 2006
    ..The overall aim of this proposal is to elucidate the molecular pathways critical to vascular barrier regulation in hypoxia and during inflammation. ..
  2. Hypoxia and Inflammation at the Vascular Interface
    Sean P Colgan; Fiscal Year: 2010
    ..In particular, these studies are designed to identify, test and unify hypotheses that adenosine functions as an endogenous anti-inflammatory through distinct mechanisms. ..
  3. ROLE OF EPITHELIA IN ISCHEMIA/REPERFUSION INJURY
    Sean Colgan; Fiscal Year: 2004
    ..The overall aim of this proposal is to elucidate the transcriptional signaling events mediating mucosal epithelial responses to hypoxia and inflammation. ..
  4. NEUTROPHIL-ENDOTHELIAL AND VASCULAR PERMEABILITY
    Sean Colgan; Fiscal Year: 2002
    ..abstract_text> ..
  5. Role of Epithelia In Ischemia Reperfusion Injury
    Sean P Colgan; Fiscal Year: 2010
    ..The overall aim of this proposal is to elucidate the transcriptional signaling events mediating mucosal epithelial responses to hypoxia and inflammation. ..