Research Topics
| Leah A CohnSummaryAffiliation: University of Missouri Country: USA Publications
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Detail Information
Publications
Seroprevalence of Ehrlichia canis, Ehrlichia chaffeensis and Ehrlichia ewingii in dogs in North AmericaMelissa J Beall
IDEXX Laboratories, Inc, Westbrook, ME, USA
Parasit Vectors 5:29. 2012..in the south and central regions of the United States where vector-borne disease prevalence has been previously difficult to ascertain, particularly beyond the metropolitan areas...
Plasma granulocyte colony-stimulating factor concentrations in neutropenic, parvoviral enteritis-infected puppiesL A Cohn
Department of Veterinary Medicine, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
J Vet Intern Med 13:581-6. 1999..Although 1 dog died while still neutropenic, plasma G-CSF concentrations declined before resolution of neutropenia in the other 6 dogs, and were again below the limits of detection in 5 of the 6 dogs at the time of resolution...
A veterinary perspective on methicillin-resistant staphylococciLeah A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Vet Emerg Crit Care (San Antonio) 20:31-45. 2010..To familiarize the reader with the epidemiology, diagnosis, and infectious and zoonotic potential of methicillin-resistant staphylococci...
Effects of fluticasone propionate dosage in an experimental model of feline asthmaLeah A Cohn
University of Missouri, College of Veterinary Medicine, Department of Veterinary Medicine and Surgery, Columbia, MO, USA
J Feline Med Surg 12:91-6. 2010..None of the dose regimens tested caused HPAA suppression. We conclude that a twice daily dosage of 44 microg fluticasone should be evaluated for the management of cats with naturally occurring inflammatory bronchial disease...
Efficacy of atovaquone and azithromycin or imidocarb dipropionate in cats with acute cytauxzoonosisL A Cohn
Department of Veterinary Medicine and Surgery, University of Missouri, Columbia, MO 65211, USA
J Vet Intern Med 25:55-60. 2011..Imidocarb or a combination of atovaquone and azithromycin (A&A) has been suggested for treatment of cats with cytauxzoonosis, but neither has been prospectively evaluated for efficacy...
Ehrlichiosis and related infectionsLeah A Cohn
College of Veterinary Medicine, University of Missouri Columbia, 379 East Campus, Clydesdale Hall, Columbia, MO 65211, USA
Vet Clin North Am Small Anim Pract 33:863-84. 2003..For animals in endemic areas, prevention of exposure to vectors can lessen the risk of disease for pets and might lessen the potential for animals to become carriers of disease for their human companions...
Endocrine and immunologic effects of inhaled fluticasone propionate in healthy dogsL A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA
J Vet Intern Med 22:37-43. 2008..Inhaled glucocorticoids reduce airway inflammation while minimizing systemic effects in several species...
Identification and characterization of an idiopathic pulmonary fibrosis-like condition in catsLeah A Cohn
Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO 65211, USA
J Vet Intern Med 18:632-41. 2004..Cats with histologic changes compatible with UIP had signs that mimicked many of the clinical findings of human IPF, and treatment response was similarly unrewarding...
Feline respiratory disease complexLeah A Cohn
Department of Veterinary Medicine and Surgery, University of Missouri Columbia, 900 East Campus Drive, Columbia, MO 65211, USA
Vet Clin North Am Small Anim Pract 41:1273-89. 2011..Although elimination of FRDC is an unrealistic goal, improved understanding can lead to strategies to minimize disease impact...
Respiratory defenses in health and diseaseLeah A Cohn
Department of Veterinary Medicine and Surgery, University of Missouri Columbia College of Veterinary Medicine, Columbia, MO 65211, USA
Vet Clin North Am Small Anim Pract 37:845-60, v. 2007..The article reviews the complex defenses used to protect the respiratory tract and also discusses the implications of failed defense systems...
The tyrosine kinase inhibitor masitinib blunts airway inflammation and improves associated lung mechanics in a feline model of chronic allergic asthmaTekla M Lee-Fowler
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Int Arch Allergy Immunol 158:369-74. 2012..We hypothesized masitinib would decrease airway eosinophilia and consequently improve pulmonary mechanics in a feline allergic asthma model...
Evaluation of subcutaneous versus mucosal (intranasal) allergen-specific rush immunotherapy in experimental feline asthmaTekla M Lee-Fowler
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Vet Immunol Immunopathol 129:49-56. 2009..Either protocol could be considered for the treatment of feline allergic asthma...
Evaluation of a continuous glucose monitoring system for use in veterinary medicineCharles E Wiedmeyer
Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
Diabetes Technol Ther 7:885-95. 2005..With the emergence of continuous glucose monitoring systems being used to provide a detailed glucose picture in humans, a commercially available system (CGMS(R), Medtronic Minimed, Northridge, CA) was examined for use in veterinary species...
The impact of oral versus inhaled glucocorticoids on allergen specific IgE testing in experimentally asthmatic catsChee Hoon Chang
Comparative Internal Medicine Laboratory, Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
Vet Immunol Immunopathol 144:437-41. 2011..Serum IgE reactivity to BGA was not significantly diminished by any treatment. In conclusion, a two-week withdrawal from GCs is adequate for IDST, but may not be necessary for serum IgE testing...
Comparison of intradermal skin testing (IDST) and serum allergen-specific IgE determination in an experimental model of feline asthmaTekla M Lee-Fowler
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
Vet Immunol Immunopathol 132:46-52. 2009..Both IDST and allergen-specific IgE determination via ELISA were specific; either test can be used to guide selection of allergens for immunotherapy. The enzymoimmunometric assay was unreliable and cannot be recommended...
Use of continuous blood glucose monitoring for animals with diabetes mellitusAmy E DeClue
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, Missouri 65211, USA
J Am Anim Hosp Assoc 40:171-3. 2004
Interstitial lung diseasesCarol R Reinero
Department of Veterinary Medicine and Surgery, University of Missouri Columbia College of Veterinary Medicine, Columbia, MO 65211, USA
Vet Clin North Am Small Anim Pract 37:937-47, vi-vii. 2007..Only with definitive recognition of these pulmonary conditions can our knowledge of the clinical course and response to therapy be improved...
What is your diagnosis? Canine herpesvirus infectionJason W Brumitt
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 227:47-8. 2005
Endotracheal nebulization of N-acetylcysteine increases airway resistance in cats with experimental asthmaCarol R Reinero
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
J Feline Med Surg 13:69-73. 2011..Further studies must be performed to evaluate if it is an effective mucolytic and/or antioxidant in cats and to determine if bronchodilator pre-treatment will negate NAC-induced bronchoconstriction...
Cardiopulmonary effects of medetomidine, oxymorphone, or butorphanol in selegiline-treated dogsJohn R Dodam
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, 379 East Campus Drive, Columbia, MO 65211, USA
Vet Anaesth Analg 31:129-37. 2004..To determine if chronic selegiline HCl administration affects the cardiopulmonary response to medetomidine, oxymorphone, or butorphanol in dogs...
Bone marrow hypoplasia associated with fenbendazole administration in a dogAnthony T Gary
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, Missouri 65211, USA
J Am Anim Hosp Assoc 40:224-9. 2004..An idiosyncratic reaction to fenbendazole was suspected based on the absence of infectious, neoplastic, autoimmune, and toxic etiologies, as well as resolution of clinical signs and pancytopenia upon drug withdrawal...
What is your diagnosis? Interstitial disease with alveolar infiltrationEfrat Yagil-Kelmer
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
J Am Vet Med Assoc 226:1983-4. 2005
Adjuvanted rush immunotherapy using CpG oligodeoxynucleotides in experimental feline allergic asthmaCarol R Reinero
Department of Veterinary Medicine and Surgery, University of Missouri Columbia, Columbia, MO 65211, USA
Vet Immunol Immunopathol 121:241-50. 2008..The exact mechanism(s) by which adjuvanted RIT alters the aberrant allergic immune response were not elucidated in this study...
Effects of subanesthetic doses of ketamine on hemodynamic and immunologic variables in dogs with experimentally induced endotoxemiaAmy E DeClue
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 69:228-32. 2008..To determine the effects of ketamine hydrochloride on hemodynamic and immunologic alterations associated with experimentally induced endotoxemia in dogs...
Evaluation of Cytauxzoon felis infection status in captive-born wild felids housed in an area endemic for the pathogenKristin M Lewis
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 241:1088-92. 2012..To determine whether apparently healthy captive-born wild felids that were not native to North America and were housed in an area endemic for Cytauxzoon felis harbored the pathogen...
Successful treatment of acute respiratory distress syndrome in 2 dogsEfrat Kelmer
Department of Small Animal Emergency and Critical Care, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel
Can Vet J 53:167-73. 2012..Few reports describe successful recovery from ARDS. Due to advances in positive pressure ventilation and improvement in the supportive care of critically ill veterinary patients, the prognosis for ARDS may improve...
Hyperaldosteronism and hyperprogesteronism in a cat with an adrenal cortical carcinomaAmy E DeClue
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Vet Intern Med 19:355-8. 2005
The effects of exercise on urinary albumin excretion in dogsAnthony T Gary
Department of Veterinary Medicine and Surgery, University of Missouri, College of Veterinary Medicine, Columbia, MO 65211, USA
J Vet Intern Med 18:52-5. 2004..On a 95% confidence interval, the proportion of dogs that might be expected to develop microalbuminuria after exercise is between 0 and 15%...
Erythrocyte survival time in Greyhounds as assessed by use of in vivo biotinylationCatherine L Garon
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 71:1033-8. 2010..To determine erythrocyte survival time in Greyhounds...
Comparison of three methods of temperature measurement in hypothermic, euthermic, and hyperthermic dogsRebecca J Greer
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 230:1841-8. 2007....
Evaluation of a continuous glucose monitoring system for use in dogs, cats, and horsesCharles E Wiedmeyer
Veterinary Medical Diagnostic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 223:987-92. 2003..Use of the CGMS will promote the diagnostic and research potential of serial glucose monitoring...
What is your diagnosis? Abscessed lymph nodeJuliene L Throop
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 226:523-4. 2005
Chronic nasal discharge in cats: 75 cases (1993-2004)Jennifer L Demko
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 230:1032-7. 2007..To identify the most common etiologic diagnosis and any historical, physical, or other diagnostic variables associated with a definitive etiologic diagnosis for chronic nasal discharge in cats. Design-Retrospective case series...
Response of healthy dogs to infusions of human serum albuminLeah A Cohn
Departments of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
Am J Vet Res 68:657-63. 2007..To evaluate the clinical and immunologic response in healthy dogs to infusions of human serum albumin (HSA)...
Lack of evidence for perinatal transmission of Cytauxzoon felis in domestic catsKristin M Lewis
University of Missouri College of Veterinary Medicine, Department of Veterinary Medicine and Surgery, Columbia, MO 65211, USA
Vet Parasitol 188:172-4. 2012..felis by microscopic slide review and PCR until they were adopted to private homes at approximately 12 weeks of age. While this does not rule out the possibility of perinatal transmission, it is unlikely to be a common phenomenon...
Effects of selegiline, phenylpropanolamine, or a combination of both on physiologic and behavioral variables in healthy dogsLeah A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
Am J Vet Res 63:827-32. 2002..CONCLUSIONS AND CLINICAL RELEVANCE: Adverse effects were not detected after administration of selegiline, PPA, or a combination of the drugs in healthy dogs...
What is your diagnosis? An ill-defined soft-tissue opacity in the caudal abdominal region and numerous metallic opacities in the soft tissues of the lumbar areaLeah A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
J Am Vet Med Assoc 220:169-70. 2002
Cortisol and aldosterone response to various doses of cosyntropin in healthy catsAmy E DeClue
Comparative Internal Medicine Laboratory, Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA
J Am Vet Med Assoc 238:176-82. 2011..To determine the lowest dose of cosyntropin on a per body weight basis that would produce maximal cortisol and aldosterone secretion and the ideal timing of blood sample collection after ACTH stimulation in healthy cats...
Fatal hemothorax following management of an esophageal foreign bodyLeah A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, 379 East Campus Drive, Columbia, Missouri 65211, USA
J Am Anim Hosp Assoc 39:251-6. 2003..The involved sections of aorta histopathogically evidenced medial necrosis, which was believed to be related to a prior disruption of blood flow through the vasa vasorum...
Locally invasive lymphangiosarcoma in a young domestic shorthairDorothy E Jackson
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, USA
J Feline Med Surg 13:796-9. 2011..Based on the mild to moderate pleomorphism, positive staining with prospero-related homeobox gene-1 (PROX-1), and the locally aggressive nature of the tumor, a final diagnosis of lymphangiosarcoma was made...
Trends in fluoroquinolone resistance of bacteria isolated from canine urinary tractsLeah A Cohn
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri-Columbia, Columbia, MO 65211, USA
J Vet Diagn Invest 15:338-43. 2003..Although the overall efficacy of FQ antimicrobials remained high with greater than 80% of isolates being susceptible, the data demonstrated an increase in the proportion of resistant bacteria isolated from the urinary tract of the dog...
D-lactic acidosis secondary to exocrine pancreatic insufficiency in a catRebecca A Packer
Department of Veterinary Medicine and Surgery, Veterinary Medical Teaching Hospital, Columbia, MO 65211, USA
J Vet Intern Med 19:106-10. 2005
The effect of photodynamic therapy on squamous cell carcinoma in a murine model: evaluation of time between intralesional injection to laser irradiationLaura D Barnes
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, 900 East Campus Drive, Columbia, MO 65211, USA
Vet J 180:60-5. 2009..Statistical significance was demonstrated between treatment groups. Although verteporfin-PDT treated mice in Tx1 and Tx2 demonstrated a lower RCTV compared to C1 and C2 mice, the differences were not statistically significant...
Acquired portosystemic shunting in two catsPaige Langdon
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri-Columbia, 65211, USA
J Am Anim Hosp Assoc 38:21-7. 2002..Two cats with acquired PSS associated with primary hepatobiliary disease are described. Relevant findings in acquired PSS are discussed, as are potential reasons for the apparently low incidence in the cat...
Prevalence of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage in three populationsS Kottler
Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, Columbia, MO, USA
J Vet Intern Med 24:132-9. 2010..A higher prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization is reported in healthcare workers compared with nonhealthcare workers...
Alveolar mucosal approach to the canine nasal cavityN H Priddy
Department of Veterinary Medicine and Surgery, Veterinary Medical Teaching Hospital, University of Missouri-Columbia, 65211, USA
J Am Anim Hosp Assoc 37:179-82. 2001..The tooth was removed through an alveolar mucosal rhinotomy. There has been no recurrence of the nasal discharge or complications associated with the surgical procedure during the 20-month follow-up period...
Polymerase chain reaction detection of Cytauxzoon felis from field-collected ticks and sequence analysis of the small subunit and internal transcribed spacer 1 region of the ribosomal RNA geneP J Bondy
Department of Veterinary Medicine and Surgery, College of Veterinary Medcine, University of Missouri, Columbia, Missouri 65211, USA
J Parasitol 91:458-61. 2005..This is the first known report of ITS-1 gene identification and sequencing for C. felis. It is also the first published investigation of genetic variation in C. felis...
Effects of platelet clumping on platelet concentrations measured by use of impedance or buffy coat analysis in dogsS L Koplitz
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65205, USA
J Am Vet Med Assoc 219:1552-6. 2001....
Xerostomia, xerophthalmia, and plasmacytic infiltrates of the salivary glands (Sjögren's-like syndrome) in a catS O Canapp
Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia 65211, USA
J Am Vet Med Assoc 218:59-65. 2001..Although reported rarely in animals, SS may be more common than currently is recognized. Most treatment regimens for SS are aimed at alleviating clinical signs...
Acylation of the lipooligosaccharide of Haemophilus influenzae and colonization: an htrB mutation diminishes the colonization of human airway epithelial cellsW Edward Swords
Department of Microbiology, University of Iowa, Iowa City, USA
Infect Immun 70:4661-8. 2002..These results implicate acylation of H. influenzae lipid A as playing a key role in the organisms' colonization of the normal airway...
