Michael X Cohen

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Reward expectation modulates feedback-related negativity and EEG spectra
    Michael X Cohen
    Department of Epilepsy and Center for Life and Brain, Sigmund Freud Str 25, Bonn 53105, Germany
    Neuroimage 35:968-78. 2007
  2. ncbi request reprint Amygdala tractography predicts functional connectivity and learning during feedback-guided decision-making
    Michael X Cohen
    Department of Epileptology, University of Bonn, Germany
    Neuroimage 39:1396-407. 2008
  3. pmc Individual differences and the neural representations of reward expectation and reward prediction error
    Michael X Cohen
    Department of Epilepsy, University of Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Soc Cogn Affect Neurosci 2:20-30. 2007
  4. doi request reprint Oscillatory activity and phase-amplitude coupling in the human medial frontal cortex during decision making
    Michael X Cohen
    University of Bonn, Germany
    J Cogn Neurosci 21:390-402. 2009
  5. ncbi request reprint Reinforcement learning signals predict future decisions
    Michael X Cohen
    Department of Epileptology and Center for Mind and Brain, University of Bonn, 53105 Bonn, Germany
    J Neurosci 27:371-8. 2007
  6. ncbi request reprint Individual differences in extraversion and dopamine genetics predict neural reward responses
    Michael X Cohen
    Department of Epileptology, University of Bonn, 53115 Bonn, Germany Center for Neuroscience, University of California, Davis, CA 95616, USA
    Brain Res Cogn Brain Res 25:851-61. 2005
  7. ncbi request reprint Functional connectivity with anterior cingulate and orbitofrontal cortices during decision-making
    M X Cohen
    Department of Epileptology, University of Bonn, Germany
    Brain Res Cogn Brain Res 23:61-70. 2005
  8. ncbi request reprint Behavioral and neural predictors of upcoming decisions
    M X Cohen
    University of Bonn, Bonn, Germany
    Cogn Affect Behav Neurosci 5:117-26. 2005
  9. doi request reprint Intracranial EEG correlates of expectancy and memory formation in the human hippocampus and nucleus accumbens
    Nikolai Axmacher
    Department of Epileptology, University of Bonn, 53105 Bonn, Germany
    Neuron 65:541-9. 2010
  10. doi request reprint Neuroelectric signatures of reward learning and decision-making in the human nucleus accumbens
    Michael X Cohen
    Department of Epileptology and Center for Life and Brain, University of Bonn, Bonn, Germany
    Neuropsychopharmacology 34:1649-58. 2009

Research Grants

Collaborators

Detail Information

Publications31

  1. pmc Reward expectation modulates feedback-related negativity and EEG spectra
    Michael X Cohen
    Department of Epilepsy and Center for Life and Brain, Sigmund Freud Str 25, Bonn 53105, Germany
    Neuroimage 35:968-78. 2007
    ..These findings suggest that the neural mechanisms of feedback processing may differ between wins and losses...
  2. ncbi request reprint Amygdala tractography predicts functional connectivity and learning during feedback-guided decision-making
    Michael X Cohen
    Department of Epileptology, University of Bonn, Germany
    Neuroimage 39:1396-407. 2008
    ..These findings provide novel insights into how the anatomy and functioning of amygdala-related brain circuits mediate different aspects of feedback-guided learning behavior...
  3. pmc Individual differences and the neural representations of reward expectation and reward prediction error
    Michael X Cohen
    Department of Epilepsy, University of Bonn, Sigmund Freud Strasse 25, Bonn, Germany
    Soc Cogn Affect Neurosci 2:20-30. 2007
    ..These findings suggest that the brain engages a reinforcement learning process during risk-taking and that individual differences play a crucial role in modeling this process...
  4. doi request reprint Oscillatory activity and phase-amplitude coupling in the human medial frontal cortex during decision making
    Michael X Cohen
    University of Bonn, Germany
    J Cogn Neurosci 21:390-402. 2009
    ..Our findings link medial frontal oscillations to decision making, with relations among activity in different frequency bands suggesting a phase-utilizing coding of feedback valence information...
  5. ncbi request reprint Reinforcement learning signals predict future decisions
    Michael X Cohen
    Department of Epileptology and Center for Mind and Brain, University of Bonn, 53105 Bonn, Germany
    J Neurosci 27:371-8. 2007
    ..These findings provide novel evidence that humans engage a reinforcement learning process to adjust representations of competing decision options...
  6. ncbi request reprint Individual differences in extraversion and dopamine genetics predict neural reward responses
    Michael X Cohen
    Department of Epileptology, University of Bonn, 53115 Bonn, Germany Center for Neuroscience, University of California, Davis, CA 95616, USA
    Brain Res Cogn Brain Res 25:851-61. 2005
    ..These results demonstrate a link between stable differences in personality, genetics, and brain functioning...
  7. ncbi request reprint Functional connectivity with anterior cingulate and orbitofrontal cortices during decision-making
    M X Cohen
    Department of Epileptology, University of Bonn, Germany
    Brain Res Cogn Brain Res 23:61-70. 2005
    ....
  8. ncbi request reprint Behavioral and neural predictors of upcoming decisions
    M X Cohen
    University of Bonn, Bonn, Germany
    Cogn Affect Behav Neurosci 5:117-26. 2005
    ..These findings provide a novel link between behavior and neural activity by demonstrating that value functions are manifested both in adjustments in behavioral strategies and in the neural activity that accompanies those adjustments...
  9. doi request reprint Intracranial EEG correlates of expectancy and memory formation in the human hippocampus and nucleus accumbens
    Nikolai Axmacher
    Department of Epileptology, University of Bonn, 53105 Bonn, Germany
    Neuron 65:541-9. 2010
    ..These results are consistent with the hypothesis that activity in a loop involving the hippocampus and the nucleus accumbens promotes encoding of unexpected events...
  10. doi request reprint Neuroelectric signatures of reward learning and decision-making in the human nucleus accumbens
    Michael X Cohen
    Department of Epileptology and Center for Life and Brain, University of Bonn, Bonn, Germany
    Neuropsychopharmacology 34:1649-58. 2009
    ....
  11. ncbi request reprint Sustained neural activity patterns during working memory in the human medial temporal lobe
    Nikolai Axmacher
    Department of Epileptology, University of Bonn, 53105 Bonn, Germany
    J Neurosci 27:7807-16. 2007
    ..Our results thus provide direct evidence for sustained neural activity patterns during working memory maintenance in the MTL, and show that these patterns depend on WM load...
  12. doi request reprint Good vibrations: cross-frequency coupling in the human nucleus accumbens during reward processing
    Michael X Cohen
    University of Bonn, Germany
    J Cogn Neurosci 21:875-89. 2009
    ..Gamma-alpha synchronization may reflect an electrophysiological gating mechanism in the human nucleus accumbens, and the phase differences in gamma-alpha coupling may reflect a reward information coding scheme similar to phase coding...
  13. pmc Nuclei accumbens phase synchrony predicts decision-making reversals following negative feedback
    Michael X Cohen
    Department of Epileptology and Center for Life and Brain and Department of Psychiatry and Psychotherapy, University of Bonn, 53105 Bonn, Germany
    J Neurosci 29:7591-8. 2009
    ..These findings suggest that a neural network including the nucleus accumbens bilaterally becomes functionally connected via theta phase synchrony to signal the need to adjust behavior...
  14. doi request reprint Activation of the caudal anterior cingulate cortex due to task-related interference in an auditory Stroop paradigm
    Sven Haupt
    Department of Epileptology, University of Bonn, Bonn, Germany
    Hum Brain Mapp 30:3043-56. 2009
    ..Taken together, we found (besides activation of regions well-known from visual Stroop tasks) activation of the very caudal and posterior part of the ACC due to task-related interference in an auditory Stroop task...
  15. ncbi request reprint Working memory maintenance contributes to long-term memory formation: neural and behavioral evidence
    Charan Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, CA 95616, USA
    J Cogn Neurosci 17:994-1010. 2005
    ....
  16. doi request reprint Connectivity-based segregation of the human striatum predicts personality characteristics
    Michael X Cohen
    Department of Epileptology and Life and Brain Center, Department of Neurocognition, University of Bonn, Sigmund Freud Street 25, Bonn 53105, Germany
    Nat Neurosci 12:32-4. 2009
    ..These findings suggest that the strength of limbic-striatal connectivity may, in part, underlie human personality traits...
  17. doi request reprint Nucleus accumbens deep brain stimulation decreases ratings of depression and anxiety in treatment-resistant depression
    Bettina H Bewernick
    Department of Psychiatry and Psychotherapy, University Hospital, 53105 Bonn, Germany
    Biol Psychiatry 67:110-6. 2010
    ..Since anhedonia is a feature of depression and there is evidence of dysfunction of the reward system, DBS to the nucleus accumbens (NAcc) might be promising...
  18. doi request reprint Interference of working memory load with long-term memory formation
    Nikolai Axmacher
    Department of Epileptology, University of Bonn, Bonn, Germany
    Eur J Neurosci 29:1501-13. 2009
    ..Taken together, these findings suggest that high WM demands interfere with LTM encoding and thus support the idea that WM and LTM processes interact in the MTL...
  19. doi request reprint Medial frontal cortex and response conflict: evidence from human intracranial EEG and medial frontal cortex lesion
    Michael X Cohen
    Department of Epileptology, University of Bonn, Bonn, Germany
    Brain Res 1238:127-42. 2008
    ..These findings provide novel evidence for the role of MFC oscillations and their relation to surface EEG-recorded potentials during action monitoring...
  20. doi request reprint Gamma-band activity in the human superior temporal sulcus during mentalizing from nonverbal social cues
    Michael X Cohen
    Department of Epileptology, University of Bonn, 53101 Bonn, Germany
    Psychophysiology 46:43-51. 2009
    ..This may be relevant for other social cognitive processes, as well as to the study of autism spectrum disorders, for which both mentalizing deficits and abnormal gamma activity have been reported...
  21. ncbi request reprint Functional connectivity with the hippocampus during successful memory formation
    Charan Ranganath
    Department of Psychology and Center for Neuroscience, University of California at Davis, Davis, CA 95616, USA
    Hippocampus 15:997-1005. 2005
    ..These findings demonstrate that successful memory formation is associated with transient increases in cortico-hippocampal interaction...
  22. doi request reprint Oxytocin enhances amygdala-dependent, socially reinforced learning and emotional empathy in humans
    Rene Hurlemann
    Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci 30:4999-5007. 2010
    ..Overall these findings provide the first demonstration that OT can facilitate amygdala-dependent, socially reinforced learning and emotional empathy in men...
  23. doi request reprint Segregating intra-amygdalar responses to dynamic facial emotion with cytoarchitectonic maximum probability maps
    Rene Hurlemann
    Department of Psychiatry, University of Bonn, 53105 Bonn, Germany
    J Neurosci Methods 172:13-20. 2008
    ..Our findings extend current models of facial emotion perception in humans by suggesting an intrinsic functional differentiation within the amygdala related to the extraction of value from facial expressions...
  24. ncbi request reprint Dopamine gene predicts the brain's response to dopaminergic drug
    Michael X Cohen
    Department of Epileptology, University of Bonn, Sigmund Freud Strasse 25, Bonn 53105, Germany
    Eur J Neurosci 26:3652-60. 2007
    ..Thus, individual variability in how dopaminergic drugs affect the brain reflects genetic disposition. These findings may help to explain the link between genetic disposition and risk for addictive disorders...
  25. ncbi request reprint Inferior temporal, prefrontal, and hippocampal contributions to visual working memory maintenance and associative memory retrieval
    Charan Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, Davis, California 95616, USA
    J Neurosci 24:3917-25. 2004
    ....
  26. ncbi request reprint Neurocomputational mechanisms of reinforcement-guided learning in humans: a review
    Michael X Cohen
    University of California, Davis, California, USA
    Cogn Affect Behav Neurosci 8:113-25. 2008
    ....
  27. ncbi request reprint Assessing transient cross-frequency coupling in EEG data
    Michael X Cohen
    Department of Epileptology and Center for Life and Brain, University of Bonn, Germany
    J Neurosci Methods 168:494-9. 2008
    ..This method might have useful applications in uncovering the electrophysiological correlates of cognitive processes...
  28. doi request reprint Covariance-based subdivision of the human striatum using T1-weighted MRI
    Michael X Cohen
    Department of Epileptology and Center for Life and Brain, University of Bonn, Germany
    Eur J Neurosci 27:1534-46. 2008
    ..These novel approaches may be useful in understanding connectivity of other regions, and changes in connectivity in patient or ageing populations...
  29. ncbi request reprint Dissociable correlates of recollection and familiarity within the medial temporal lobes
    Charan Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, 1544 Newton Ct, Davis, CA 95616, USA
    Neuropsychologia 42:2-13. 2004
    ..Collectively, these results support the view that different subregions within the MTL memory system implement unique encoding processes that differentially support familiarity and recollection...
  30. ncbi request reprint Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression
    Thomas E Schlaepfer
    Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany
    Neuropsychopharmacology 33:368-77. 2008
    ..These preliminary findings suggest that DBS to the nucleus accumbens might be a hypothesis-guided approach for refractory major depression...
  31. pmc A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration
    Jennifer L Snead
    Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158, USA
    Chem Biol 14:1261-72. 2007
    ..Finally, an examination of Cdc5 binding by SPB-localized proteins expanded our knowledge of Cdc5 function at the SPB...

Research Grants1

  1. Orbitofrontal cortex, impulsivity, reinforcements
    Michael Cohen; Fiscal Year: 2006
    ..I will test the hypothesis that this is reflected both in the ability to use reinforcements to guide future behavior, and in the extent to which OFC is recurited during these behavioral adjustments. ..