Research Topics
Species | Ira L CohenSummaryAffiliation: University at Albany Country: USA Publications
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Detail Information
Publications
Alteration in amino-glycerophospholipids levels in the plasma of children with autism: a potential biochemical diagnostic markerVed Chauhan
NYS Institute for Basic Research in Developmental Disabilities, Staten Island, New York, NY 10314, USA
Life Sci 74:1635-43. 2004..It is proposed that plasma AGP levels may function as a potential diagnostic marker for autism...
Autism severity is associated with child and maternal MAOA genotypesI L Cohen
Department of Psychology, NYS Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA
Clin Genet 79:355-62. 2011..These findings indicate the importance of considering maternal genotype in examining associations of MAOA and other genes with behavior in male offspring...
Association of autism severity with a monoamine oxidase A functional polymorphismI L Cohen
Departments of Psychology, Cytogenetics and Human Genetics, Staten Island, New York 10314, USA
Clin Genet 64:190-7. 2003..We conclude that functional MAOA-uVNTR alleles may act as a genetic modifier of the severity of autism in males...
A large scale study of the psychometric characteristics of the IBR Modified Overt Aggression Scale: findings and evidence for increased self-destructive behaviors in adult females with autism spectrum disorderIra L Cohen
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, 10314, USA
J Autism Dev Disord 40:599-609. 2010..Our data suggest that adult females with autism are a unique group and support the notion that mood and anxiety disorders play a role in self-destructive behaviors in this population...
Parent PDD behavior inventory profiles of young children classified according to autism diagnostic observation schedule-generic and autism diagnostic interview-revised criteriaIra L Cohen
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314, USA
J Autism Dev Disord 40:246-54. 2010..Sensitivity, specificity and positive and negative predictability measures were quite good for these measures. It was concluded that the PDDBI is useful in assisting in the differential diagnosis of autism spectrum disorder...
Maternal recurrent mood disorders and high-functioning autismIra L Cohen
Dept of Psychology and George A Jervis Clinic, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA
J Autism Dev Disord 36:1077-88. 2006..Various genetic models are discussed. It is hypothesized that genes associated with recurrent depression in women may exert a "protective" effect on cognition and adaptive functioning in children with PDD...
Differences between the pattern of developmental abnormalities in autism associated with duplications 15q11.2-q13 and idiopathic autismJerzy Wegiel
Department of Developmental Neurobiology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York 10314, USA
J Neuropathol Exp Neurol 71:382-97. 2012..04). The different spectrum and higher prevalence of developmental neuropathologic findings in the dup(15) cohort than in cases with idiopathic autism may contribute to the high risk of early onset of seizures and sudden death...
Sera from children with autism alter proliferation of human neuronal progenitor cells exposed to oxidationBozena Mazur-Kolecka
Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities, Staten Island, New York, USA
Neurotox Res 16:87-95. 2009..These results suggest that altered response of NPCs to oxidative stress may play a role in the etiology of autism...
Abnormal intracellular accumulation and extracellular Aβ deposition in idiopathic and Dup15q11.2-q13 autism spectrum disordersJerzy Wegiel
Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities, Staten Island, New York, United States of America
PLoS ONE 7:e35414. 2012..It has been shown that amyloid ß (Aβ), a product of proteolytic cleavage of the amyloid β precursor protein (APP), accumulates in neuronal cytoplasm in non-affected individuals in a cell type-specific amount...
Neonatal brainstem function and 4-month arousal-modulated attention are jointly associated with autismIra L Cohen
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314, USA
Autism Res 6:11-22. 2013..The joint occurrence of initially abnormal neonatal ABRs and preference for more stimulation at 4 months, both indices of early brainstem dysfunction, may be a marker for the development of autism in this cohort...
Early medical and behavioral characteristics of NICU infants later classified with ASDBernard Z Karmel
New York State Institute for Basic Research in Developmental Disabilities, Department of Infant Development, 1050 Forest Hill Rd, Staten Island, NY 10314, USA
Pediatrics 126:457-67. 2010..Recent evidence suggests higher prevalence of autism spectrum disorder (ASD) in NICU graduates. This aim of this study was to identify retrospectively early behaviors found more frequently in NICU infants who went on to develop ASD...
Treatment of previously undiagnosed psychiatric disorders in persons with developmental disabilities decreased or eliminated self-injurious behaviorJohn A Tsiouris
Institute for Basic Research in Developmental Disabilities, George A Jervis Clinic, 1050 Forest Hill Rd, Staten Island, NY 10314, USA
J Clin Psychiatry 64:1081-90. 2003..Results have varied, and no one psychotropic drug has been indicated for SIB. In this prospective, open clinical study, psychotropic drugs were used to treat the previously undiagnosed psychiatric disorder in persons exhibiting SIB...
Prevalence of psychotropic drug use in adults with intellectual disability: positive and negative findings from a large scale studyJohn A Tsiouris
George A Jervis Clinic, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Rd, Staten Island, NY 10314, USA
J Autism Dev Disord 43:719-31. 2013....
The neuropathology of autism: defects of neurogenesis and neuronal migration, and dysplastic changesJerzy Wegiel
Department of Developmental Neurobiology, NYS Institute for Basic Research in Developmental Disabilities IBR, 1050 Forest Hill Road, Staten Island, NY 10314, USA
Acta Neuropathol 119:755-70. 2010....
Alpha2 macroglobulin elevation without an acute phase response in depressed adults with Down's syndrome: implicationsJ A Tsiouris
George A Jervis Clinic, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, New York 10314, USA
J Intellect Disabil Res 44:644-53. 2000..Further studies are needed to confirm that alpha2M elevation is specific to depression and that it might provide a helpful marker for the diagnosis of depression in people with ID...
Criterion-related validity of the PDD Behavior InventoryIra L Cohen
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA
J Autism Dev Disord 33:47-53. 2003..These results confirm the validity of the PDDBI and suggest that the scale will have value in assessing treatment-related changes in maladaptive and adaptive behaviors associated with PDD...
The PDD Behavior Inventory: a rating scale for assessing response to intervention in children with pervasive developmental disorderIra L Cohen
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314, USA
J Autism Dev Disord 33:31-45. 2003..It was concluded that the PDDBI is both reliable and valid and is useful in providing information not typically available in most instruments used to assess children with PDD...
Conversational analyses of males with fragile X, Down syndrome, and autism: comparison of the emergence of deviant languageV Sudhalter
Department of Psychology, New York State Institute for Basic Research in Developmental Disabilities, Staten Island 10314
Am J Ment Retard 94:431-41. 1990..Possible explanations for this etiologically specific language deviance were discussed...
Altered development of neuronal progenitor cells after stimulation with autistic blood seraBozena Mazur-Kolecka
Department of Developmental Neurobiology, New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Rd, Staten Island, NY 10314, USA
Brain Res 1168:11-20. 2007..Further studies in this cell culture model may explain some of the cellular alterations described in autistic patients...
