Thomas Cline

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Evolution of the Drosophila feminizing switch gene Sex-lethal
    Thomas W Cline
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 186:1321-36. 2010
  2. pmc Recruitment of the proneural gene scute to the Drosophila sex-determination pathway
    Lisa A Wrischnik
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 165:2007-27. 2003
  3. pmc Reflections on a path to sexual commitment
    Thomas W Cline
    Department of Molecular and Cell Biology, University of California, Berkeley, 94720 3204, USA
    Genetics 169:1179-85. 2005
  4. ncbi request reprint The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription
    John R ten Bosch
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3204, USA
    Development 133:1967-77. 2006
  5. pmc Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes
    Melissa M Harrison
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Dev Biol 345:248-55. 2010
  6. pmc Sexual back talk with evolutionary implications: stimulation of the Drosophila sex-determination gene sex-lethal by its target transformer
    Scott G Siera
    Department of Molecular and Cell Biology, Division of Genetics, Genomics and Development, University of California, Berkeley, California 94720 3204, USA
    Genetics 180:1963-81. 2008
  7. pmc Effects of Wolbachia infection and ovarian tumor mutations on Sex-lethal germline functioning in Drosophila
    Sha Sun
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 181:1291-301. 2009
  8. ncbi request reprint A host parasite interaction rescues Drosophila oogenesis defects
    Diana J Starr
    Department of Molecular and Cell Biology, 401 Barker Hall, University of California, Berkeley, California 94720 3204, USA
    Nature 418:76-9. 2002
  9. pmc Drosophila melanogaster male somatic cells feminized solely by TraF can collaborate with female germ cells to make functional eggs
    Daniel S Evans
    Division of Genetics, Genomics and Development, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 175:631-42. 2007

Research Grants

  1. REGULATION OF SEX-SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 2002
  2. REGULATION OF SEX-SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 1990
  3. REGULATION OF SEX-SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 1993
  4. REGULATION OF SEX SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 2006

Collaborators

  • Melissa M Harrison
  • Sha Sun
  • Scott G Siera
  • Daniel S Evans
  • John R ten Bosch
  • Lisa A Wrischnik
  • Diana J Starr
  • Joseph A Benavides
  • John R Timmer
  • Lisa A Megna

Detail Information

Publications9

  1. pmc Evolution of the Drosophila feminizing switch gene Sex-lethal
    Thomas W Cline
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 186:1321-36. 2010
    ..The potential evolutionary relevance of these nonessential functions is discussed...
  2. pmc Recruitment of the proneural gene scute to the Drosophila sex-determination pathway
    Lisa A Wrischnik
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 165:2007-27. 2003
    ..The screen that yielded new sc alleles also generated autosomal duplications that argue against the textbook view that fruit fly sex signal evolution recruited a set of autosomal signal elements comparable to the XSEs...
  3. pmc Reflections on a path to sexual commitment
    Thomas W Cline
    Department of Molecular and Cell Biology, University of California, Berkeley, 94720 3204, USA
    Genetics 169:1179-85. 2005
  4. ncbi request reprint The TAGteam DNA motif controls the timing of Drosophila pre-blastoderm transcription
    John R ten Bosch
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720 3204, USA
    Development 133:1967-77. 2006
    ....
  5. pmc Grainyhead and Zelda compete for binding to the promoters of the earliest-expressed Drosophila genes
    Melissa M Harrison
    Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA
    Dev Biol 345:248-55. 2010
    ....
  6. pmc Sexual back talk with evolutionary implications: stimulation of the Drosophila sex-determination gene sex-lethal by its target transformer
    Scott G Siera
    Department of Molecular and Cell Biology, Division of Genetics, Genomics and Development, University of California, Berkeley, California 94720 3204, USA
    Genetics 180:1963-81. 2008
    ..The tra-mediated Sxl feedback in Drosophila may be a vestige of regulatory redundancy that facilitated the evolutionary transition from tra to Sxl as the master sex switch...
  7. pmc Effects of Wolbachia infection and ovarian tumor mutations on Sex-lethal germline functioning in Drosophila
    Sha Sun
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 181:1291-301. 2009
    ..Clearly Sxl and otu work together in the female germline. These studies of meiosis in Sxl mutant females revealed that X chromosome recombination is considerably more sensitive than autosomal recombination to reduced Sxl activity...
  8. ncbi request reprint A host parasite interaction rescues Drosophila oogenesis defects
    Diana J Starr
    Department of Molecular and Cell Biology, 401 Barker Hall, University of California, Berkeley, California 94720 3204, USA
    Nature 418:76-9. 2002
    ..Furthermore, demonstration that a parasite infection can counteract the deleterious effects of mutations in host genes illustrates how hosts might become dependent on parasites...
  9. pmc Drosophila melanogaster male somatic cells feminized solely by TraF can collaborate with female germ cells to make functional eggs
    Daniel S Evans
    Division of Genetics, Genomics and Development, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3204, USA
    Genetics 175:631-42. 2007
    ..The unexpected observation that some Tra(F)-feminized gynanders failed to lay their eggs showed there to be diplo-X cells outside the gonad for which Tra(F)-feminized haplo-X cells cannot substitute...

Research Grants17

  1. REGULATION OF SEX-SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 2002
    ..4) Explore the possibility of homeostatic negative feedback regulation between Drosophila sex determination and X-chromosome dosage compensation. ..
  2. REGULATION OF SEX-SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 1990
    ..Information from the experiments proposed here should provide the background needed to extend molecular analysis of this system into important new areas...
  3. REGULATION OF SEX-SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 1993
    ....
  4. REGULATION OF SEX SPECIFIC GENES IN DROSOPHILA
    Thomas Cline; Fiscal Year: 2006
    ..abstract_text> ..