Research Topics
Genomes and GenesSpecies | Daniel ClauwSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
Does acupuncture help reduce pain in patients with fibromyalgia?Daniel J Clauw
Division of Rheumatology, University of Michigan, Ann Arbor, 48106, USA
Nat Clin Pract Rheumatol 1:76-7. 2005
Managing chronic pain with nonopioid analgesics: a multidisciplinary consultDaniel Clauw
Division of Rheumatology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, USA
Am J Med 125:S1. 2012..A multimodal/multidisciplinary approach incorporating pharmacologic and nonpharmacologic therapy into a program that includes more than 1 discipline is important to improve outcomes in patients with chronic pain...
Activity pacing for osteoarthritis symptom management: study design and methodology of a randomized trial testing a tailored clinical approach using accelerometers for veterans and non-veteransSusan L Murphy
Department of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA
BMC Musculoskelet Disord 12:177. 2011..In a pilot study, we found that participants who underwent a tailored activity pacing intervention had reduced fatigue interference with daily activities. We are now conducting a full-scale trial...
Subgroups of older adults with osteoarthritis based upon differing comorbid symptom presentations and potential underlying pain mechanismsSusan L Murphy
Department of Physical Medicine and Rehabilitation, University of Michigan, 300 North Ingalls, 9th Floor, Ann Arbor, MI 48109 2007, USA
Arthritis Res Ther 13:R135. 2011....
Milnacipran for the treatment of fibromyalgia in adults: a 15-week, multicenter, randomized, double-blind, placebo-controlled, multiple-dose clinical trialDaniel J Clauw
Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan Medical School, Ann Arbor, Michigan 48106, USA
Clin Ther 30:1988-2004. 2008..Preclinical and clinical studies have suggested that milnacipran, a dual norepinephrine-serotonin reuptake inhibitor, may be efficacious in the treatment of fibromyalgia (FM)...
Perspectives on fatigue from the study of chronic fatigue syndrome and related conditionsDaniel J Clauw
Chronic Pain and Fatigue Research Center, The University of Michigan, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106, USA
PM R 2:414-30. 2010..The relative contributions of each of these abnormalities to the profound fatigue associated with CFS need to be explored further to better evaluate and treat the syndrome...
Pharmacotherapy for patients with fibromyalgiaDaniel J Clauw
Division of Rheumatology, Department of Internal Medicine, and Michigan Institute for Clinical and Health Research, University of Michigan Medical School, Ann Arbor, USA
J Clin Psychiatry 69:25-9. 2008..g., education, aerobic exercise, and cognitive-behavioral therapy) is also discussed...
Relationship between stress and pain in work-related upper extremity disorders: the hidden role of chronic multisymptom illnessesDaniel J Clauw
Division of Rheumatology, Immunology, and Allergy, Georgetown University Medical Center, Washington, DC, USA
Am J Ind Med 41:370-82. 2002..In such a scenario, the chronic regional pain and other symptoms that the individual is experiencing would be attributable to the CMI rather than to tissue damage or a biomechanical dysfunction of the upper-extremity...
Chronic widespread pain and fibromyalgia: what we know, and what we need to knowDaniel J Clauw
Division of Rheumatology, Department of Medicine, University of Michigan Medical School, 101 Simpson, Ann Arbor, MI 48109 0723, USA
Best Pract Res Clin Rheumatol 17:685-701. 2003..g. NSAIDs, corticosteroids), neuroactive compounds [especially those that raise central levels of noradrenaline (norepinephrine) or serotonin] are most effective for treating central pain...
A Chronic Fatigue Syndrome - related proteome in human cerebrospinal fluidJames N Baraniuk
Georgetown University Proteomics Laboratory, Division of Rheumatology, Immunology and Allergy, Room B 105, Lower Level Kober Cogan Building, Georgetown University, Washington, DC 20007 2197, USA
BMC Neurol 5:22. 2005..Neurological dysfunction is common. We assessed cerebrospinal fluid to find proteins that were differentially expressed in this CFS-spectrum of illnesses compared to control subjects...
Improving physical functional status in patients with fibromyalgia: a brief cognitive behavioral interventionDavid A Williams
Department of Psychiatry, Georgetown University Medical Center, Washington, DC 20007, USA
J Rheumatol 29:1280-6. 2002..Sustained improvement in physical functional status was the primary goal of a brief, 6 session cognitive behavioral therapy (CBT) protocol for fibromyalgia (FM)...
Covariates of corticotropin-releasing hormone (CRH) concentrations in cerebrospinal fluid (CSF) from healthy humansJames N Baraniuk
Division of Rheumatology, Immunology and Allergy, Room GL 002, Lower Level Gorman Building, Georgetown University, 3800 Reservoir Road, NW, Washington, DC 20007 2197, USA
BMC Neurosci 5:58. 2004..CRHCSF was first correlated with demographic, vital sign, HPA axis, validated questionnaire domains, baseline and maximal responses to pain, exercise and other stressors. Significant factors were used for linear regression modeling...
What do tender points measure? Influence of distress on 4 measures of tendernessFrank Petzke
Chronic Pain and Fatigue Research Center, Georgetown University Medical Center, Washington, DC, USA
J Rheumatol 30:567-74. 2003..To examine the relationship between current pain, distress, and ascending and random measures of tenderness...
Cerebrospinal fluid levels of opioid peptides in fibromyalgia and chronic low back painJames N Baraniuk
Chronic Pain and Fatigue Research Center, Division of Rheumatology, Immunology and Allergy, Room B107, Lower Level Kober Cogan Building, Georgetown University, 3800 Reservoir Road, N, W, Washington, DC 20007 2197, USA
BMC Musculoskelet Disord 5:48. 2004..The mechanism(s) of nociceptive dysfunction and potential roles of opioid neurotransmitters are unresolved in the chronic pain syndromes of fibromyalgia and chronic low back pain...
Evidence of augmented central pain processing in idiopathic chronic low back painThorsten Giesecke
University of Michigan, Ann Arbor, MI 48106, USA
Arthritis Rheum 50:613-23. 2004..These findings are consistent with the occurrence of augmented central pain processing in patients with idiopathic CLBP...
Therapy Insight: fibromyalgia--a different type of pain needing a different type of treatmentDina Dadabhoy
Chronic Pain and Fatigue Research Center, The University of Michigan, 24 Frank Lloyd Wright Drive, Box 385, Ann Arbor, MI 48106, USA
Nat Clin Pract Rheumatol 2:364-72. 2006....
Dynamic levels of glutamate within the insula are associated with improvements in multiple pain domains in fibromyalgiaRichard E Harris
University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
Arthritis Rheum 58:903-7. 2008..This study was carried out to investigate the relationship between changing levels of Glu within the insula and changes in multiple pain domains in patients with FM...
A psychophysical study of auditory and pressure sensitivity in patients with fibromyalgia and healthy controlsMichael E Geisser
Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48108, USA
J Pain 9:417-22. 2008..These findings may also help to explain why persons with FM display a number of comorbid physical symptoms other than pain...
Decreased central mu-opioid receptor availability in fibromyalgiaRichard E Harris
Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan 48109, USA
J Neurosci 27:10000-6. 2007..These findings indicate altered endogenous opioid analgesic activity in FM and suggest a possible reason for why exogenous opiates appear to have reduced efficacy in this population...
Development and evaluation of the University of Michigan's Practice-Oriented Research Training (PORT) ProgramSusan L Murphy
Department of Physical Medicine and Rehabilitation, University of Michigan, USA
Am J Occup Ther 64:796-803. 2010..Given the initial successes, this program represents a promising model for providing research training to practicing clinicians...
Diffusion-weighted and diffusion tensor imaging in fibromyalgia patients: a prospective study of whole brain diffusivity, apparent diffusion coefficient, and fraction anisotropy in different regions of the brain and correlation with symptom severityPia C Sundgren
Department of Radiology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109-0030, USA
Acad Radiol 14:839-46. 2007
Fibromyalgia: update on mechanisms and managementDaniel J Clauw
Division of Rheumatology, Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
J Clin Rheumatol 13:102-9. 2007
Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: results of the two-year multinational knee osteoarthritis stClifton O Bingham
Division of Rheumatology, Johns Hopkins University, 5200 Eastern Avenue, Mason F Lord Building, Center Tower, Room 404, Baltimore, MD 21224, USA
Arthritis Rheum 54:3494-507. 2006....
Is acupuncture more effective than sham acupuncture in relieving pain in patients with low back pain?Daniel J Clauw
University of Michigan Medical School, Division of Rheumatology, Department of Medicine, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
Nat Clin Pract Rheumatol 2:362-3. 2006
Cerebrospinal fluid corticotropin-releasing factor concentration is associated with pain but not fatigue symptoms in patients with fibromyalgiaSamuel A McLean
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
Neuropsychopharmacology 31:2776-82. 2006..Further studies are needed to better understand the nature of the association between CSF CRF and pain symptoms in FM...
Assessor status influences pain recallDavid A Williams
Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
J Pain 8:343-8. 2007..This study found evidence of a status-based bias in which physicians elicited lower ratings of previously experienced pain associated with treatment procedures than did staff members of lower status...
Contributions of change in clinical status parameters to Patient Global Impression of Change (PGIC) scores among persons with fibromyalgia treated with milnacipranMichael E Geisser
Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, MI48108, USA
Pain 149:373-8. 2010..Several domains were associated with PGIC ratings, highlighting the need to assess multiple outcomes in clinical trials of treatments for FM...
Fibromyalgia: an overviewDaniel J Clauw
Chronic Pain and Fatigue Research Center, Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan 48106, USA
Am J Med 122:S3-S13. 2009....
Commentary on the EULAR recommendations for the management of fibromyalgiaDaniel J Clauw
Clinical and Translational Research at University of Michigan, Ann Arbor, MI, USA
Nat Clin Pract Rheumatol 4:392-3. 2008
Elevated insular glutamate in fibromyalgia is associated with experimental painRichard E Harris
University of Michigan, Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
Arthritis Rheum 60:3146-52. 2009....
Objective measures of disordered sleep in fibromyalgiaRonald D Chervin
Michael S Aldrich Sleep Disorders Laboratory, Ann Arbor, MI 48109 5845, USA
J Rheumatol 36:2009-16. 2009..However, measures that consistently and objectively distinguish FM patients remain elusive...
Understanding fibromyalgia: lessons from the broader pain research communityDavid A Williams
Chronic Pain and Fatigue Research Center, The University of Michigan, Ann Arbor, Michigan 48106, USA
J Pain 10:777-91. 2009....
Traditional Chinese acupuncture and placebo (sham) acupuncture are differentiated by their effects on mu-opioid receptors (MORs)Richard E Harris
Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA
Neuroimage 47:1077-85. 2009..These findings suggest that divergent MOR processes may mediate clinically relevant analgesic effects for acupuncture and sham acupuncture...
No consistent difference in gray matter volume between individuals with fibromyalgia and age-matched healthy subjects when controlling for affective disorderMichael C Hsu
Department of Physical Medicine and Rehabilitation, University of Michigan Chronic Pain and Fatigue Research Center, 24 Frank Lloyd Wright Drive, Lobby M, PO Box 385, Ann Arbor, MI 48106, USA
Pain 143:262-7. 2009..470, p<.001). No other significant clusters were found on ROI-based analysis. Our results emphasize the importance of correcting for AD when carrying out VBM studies in chronic pain...
Effects of lifestyle physical activity on perceived symptoms and physical function in adults with fibromyalgia: results of a randomized trialKevin R Fontaine
Division of Rheumatology, Johns Hopkins University School of Medicine, 5200 Eastern Avenue, Baltimore, MD 21224, USA
Arthritis Res Ther 12:R55. 2010....
Internet-enhanced management of fibromyalgia: a randomized controlled trialDavid A Williams
Chronic Pain and Fatigue Research Center, University of Michigan, 24 Frank Lloyd Wright Drive, Lobby M, Ann Arbor, MI 48106, USA
Pain 151:694-702. 2010..While not everyone is expected to benefit from this approach, this study demonstrated that non-pharmacological interventions can be efficiently integrated into routine clinical practice with positive outcomes...
The impact of momentary pain and fatigue on physical activity in women with osteoarthritisSusan L Murphy
University of Michigan, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Arthritis Rheum 59:849-56. 2008....
Comorbid somatic symptoms and functional status in patients with fibromyalgia and chronic fatigue syndrome: sensory amplification as a common mechanismMichael E Geisser
Chronic Pain and Fatigue Research Center, Dept of Internal Medicine, Div of Rheumatology, Univ of Michigan, Ann Arbor, MI 48108, USA
Psychosomatics 49:235-42. 2008..Somatic symptoms are common in conditions such as fibromyalgia (FM) and chronic fatigue syndrome (CFS)...
Comparison of clinical and evoked pain measures in fibromyalgiaRichard E Harris
Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48106, USA
J Pain 7:521-7. 2006..Pressure pain testing that applies stimuli in a random order is associated with improvements in clinical pain, but this association was not stronger than other experimental techniques...
The association between experimental and clinical pain measures among persons with fibromyalgia and chronic fatigue syndromeMichael E Geisser
Chronic Pain and Fatigue Research Center, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI, USA
Eur J Pain 11:202-7. 2007..These findings merit consideration when designing experimental studies of clinical pain associated with FM and CFS...
Treatment of fibromyalgia with formula acupuncture: investigation of needle placement, needle stimulation, and treatment frequencyRichard E Harris
Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI 48106, USA
J Altern Complement Med 11:663-71. 2005..DESIGN/SETTINGS/SUBJECTS: A single-site, single-blind, randomized trial of 114 participants diagnosed with fibromyalgia for at least 1 year was performed...
Biomedical models of fibromyalgiaSamuel A McLean
University of Michigan Chronic Pain and Fatigue Research Center, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 48106, USA
Disabil Rehabil 27:659-65. 2005..A large body of data indicates a neurobiological basis for these disorders, but this information has not been effectively transmitted to many medical professionals...
Fibromyalgia after motor vehicle collision: evidence and implicationsSamuel A McLean
Department of Emergency Medicine and The Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Traffic Inj Prev 6:97-104. 2005..Assess currently available evidence regarding the ability of a motor vehicle collision (MVC) to trigger the development of fibromyalgia (FM)...
Applying exercise to the management of fibromyalgiaKirsten Ambrose
Chronic Pain and Fatigue Research Program, University of Michigan, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48109 0483, USA
Curr Pain Headache Rep 7:348-54. 2003..This article reviews the exercise and CMI literature and provides a model for applying these evidence-based guidelines to a clinical population...
Knee pain and radiographic osteoarthritis interact in the prediction of levels of self-reported disabilityDavid A Williams
The University of Michigan, Ann Arbor, MI 48106, USA
Arthritis Rheum 51:558-61. 2004..To determine predictors of disability depending on whether joint deformity and pain reporting exist independently or concurrently...
Predicting chronic symptoms after an acute "stressor"--lessons learned from 3 medical conditionsSamuel A McLean
Department of Emergency Medicine, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, P O Box 385, Ann Arbor, MI 48106, USA
Med Hypotheses 63:653-8. 2004....
The development of persistent pain and psychological morbidity after motor vehicle collision: integrating the potential role of stress response systems into a biopsychosocial modelSamuel A McLean
Department of Emergency Medicine, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Psychosom Med 67:783-90. 2005....
Pain assessment in patients with fibromyalgia syndrome: a consideration of methods for clinical trialsDavid A Williams
Department of Medicine, Division of Rheumatology, University of Michigan, Ann Arbor 48106, USA
Clin J Pain 20:348-56. 2004..Baseline characteristics, characteristics over time, and compliance were evaluated for each of the methods...
Momentary relationship between cortisol secretion and symptoms in patients with fibromyalgiaSamuel A McLean
Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
Arthritis Rheum 52:3660-9. 2005....
Characterization and consequences of pain variability in individuals with fibromyalgiaRichard E Harris
Chronic Pain and Fatigue Research Center, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, PO Box 385, Ann Arbor, MI 48106, USA
Arthritis Rheum 52:3670-4. 2005..We used electronic assessment data derived from a study of patients with fibromyalgia (FM) to examine variability of pain over time and to investigate the implications of pain fluctuation in the context of a clinical trial...
Fibromyalgia: progress in diagnosis and treatmentDina Dadabhoy
Division of Rheumatology, Department of Medicine, Chronic Pain and Fatigue Research Center, The University of Michigan, 24 Frank Lloyd Wright Drive, Box 385, Ann Arbor, MI 48106, USA
Curr Pain Headache Rep 9:399-404. 2005..Current evidence advocates a multifaceted program emphasizing patient education, medications for improving symptoms, and aggressive use of exercise and cognitive-behavioral approaches to retain or restore function...
Unexplained symptoms after terrorism and war: an expert consensus statementDaniel J Clauw
Department of Medicine, University of Michigan School of Medicine, USA
J Occup Environ Med 45:1040-8. 2003..An international, multidisciplinary, and multiinstitutional consensus project was completed to summarize current knowledge on unexplained symptoms after terrorism and war...
The effect of brief exercise cessation on pain, fatigue, and mood symptom development in healthy, fit individualsJennifer M Glass
Department of Psychiatry and Institute for Social Research, University of Michigan, Ann Arbor, MI, USA
J Psychosom Res 57:391-8. 2004..In particular, we focus on the effect of deprivation of routine aerobic exercise on the development of somatic symptoms...
Quantitative sensory testing in vulvodynia patients and increased peripheral pressure pain sensitivityJutta Giesecke
Chronic Pain and Fatigue Research Program, Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, Michigan 48109-0708, USA
Obstet Gynecol 104:126-33. 2004..Both the novel vulvodolorimeter and the thumb pressure stimulator may assist in future experimental tests of this and related hypotheses...
The relationship between depression, clinical pain, and experimental pain in a chronic pain cohortThorsten Giesecke
University of Michigan, Ann Arbor, USA
Arthritis Rheum 52:1577-84. 2005..The implication for treatment is that addressing an individual's depression (e.g., by prescribing an antidepressant medication that has no analgesic properties) will not necessarily have an impact on the sensory dimension of pain...
The relationship between disease activity, sleep, psychiatric distress and pain sensitivity in rheumatoid arthritis: a cross-sectional studyYvonne C Lee
Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, PBB B3, Boston, MA 02115, USA
Arthritis Res Ther 11:R160. 2009..The etiology of RA pain is likely multifactorial, including both inflammatory and non-inflammatory components. In this study, we examine the association between disease activity, sleep, psychiatric distress and pain sensitivity in RA...
Durability of therapeutic response to milnacipran treatment for fibromyalgia. Results of a randomized, double-blind, monotherapy 6-month extension studyDon L Goldenberg
Department of Medicine, Newton Wellesley Hospital, Newton, Massachusetts 02462, USA
Pain Med 11:180-94. 2010....
Biomarkers in fibromyalgiaJacob N Ablin
University of Michigan Chronic Pain and Fatigue Research Center, Ann Arbor, MI 48106, USA
Curr Pain Headache Rep 13:343-9. 2009....
Subgrouping of fibromyalgia patients on the basis of pressure-pain thresholds and psychological factorsThorsten Giesecke
University of Michigan, Ann Arbor, USA
Arthritis Rheum 48:2916-22. 2003....
An 'Honest Broker' mechanism to maintain privacy for patient care and academic medical researchAndrew D Boyd
Department of Psychiatry, University of Michigan Medical Center, Ann Arbor, MI, USA
Int J Med Inform 76:407-11. 2007..This problem cuts across all electronic record sources from patient care records to academic medical research records...
Treatment of fatigue in fibromyalgiaEmma K Guymer
Division of Rheumatology/Allergy/Immunology, Georgetown University Medical Center, 3800 Reservoir Road NW, Washington, DC 20007, USA
Rheum Dis Clin North Am 28:367-78. 2002..Improvements in pharmacologic therapies will come from new insights into mechanisms, especially those that might only be present in subsets of patients and would respond to more targeted therapies...
How do we know that the pain in fibromyalgia is "real"?Richard E Harris
Department of Medicine, Division of Rheumatology, University of Michigan Medical Center, 24 Frank Lloyd Wright Drive, Ann Arbor, MI 18106, USA
Curr Pain Headache Rep 10:403-7. 2006..Future studies that focus on central neurobiological and/or genetic influences in fibromyalgia may bring insight into mechanisms of this problematic disease and ultimately result in improved treatments...
Antecedent nonbladder syndromes in case-control study of interstitial cystitis/painful bladder syndromeJohn W Warren
Department of Medicine, Epidemiology and Preventive Medicine, and Neurology, University of Maryland School of Medicine, Baltimore, Maryland, USA
Urology 73:52-7. 2009..Probing for clues to the pathogenesis of interstitial cystitis/painful bladder syndrome (IC/PBS), we sought antecedent nonbladder syndromes that distinguished incident IC/PBS cases from matched controls...
Assessing and diagnosing fibromyalgia in the clinical settingDaniel J Clauw
Division of Rheumatology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
J Clin Psychiatry 69:e33. 2008..This activity provides a sample assessment and diagnosis in a clinical situation...
Cognitive behavioral therapy and aerobic exercise for Gulf War veterans' illnesses: a randomized controlled trialSam T Donta
VA Medical Center, Boston, Mass, USA
JAMA 289:1396-404. 2003..Neither treatment had a significant impact on pain. CONCLUSION: Our results suggest that CBT and/or exercise can provide modest relief for some of the symptoms of chronic multisymptom illnesses such as GWVI...
Functional magnetic resonance imaging evidence of augmented pain processing in fibromyalgiaRichard H Gracely
National Institute of Dental and Craniofacial Research, NIH, Bethesda, Maryland, USA
Arthritis Rheum 46:1333-43. 2002....
Increased pain sensitivity in fibromyalgia: effects of stimulus type and mode of presentationFrank Petzke
Department of Anesthesiology, University of Cologne, Cologne, Germany
Pain 105:403-13. 2003..The increased sensitivity to both pressure and thermal stimuli for threshold and suprathreshold stimuli in FM patients is consistent with central augmentation of pain processing...
Self-reported symptoms before and after September 11 in patients with fibromyalgiaDavid A Williams
JAMA 289:1637-8. 2003
Differences in unpleasantness induced by experimental pressure pain between patients with fibromyalgia and healthy controlsFrank Petzke
Department of Anesthesiology of the University of Cologne, Germany
Eur J Pain 9:325-35. 2005..Clinical pain in patients with FM was perceived to be more unpleasant than the evoked pain stimuli. These results are consistent with the concept that chronic pain may reduce the relative unpleasantness of evoked pain sensations...
Efficacy of milnacipran in patients with fibromyalgiaR Michael Gendreau
Cypress Biosciences, 4350 Executive Drive, San Diego, CA 92121, USA
J Rheumatol 32:1975-85. 2005..Milnacipran, a nontricyclic compound that inhibits the reuptake of both serotonin and norepinephrine, may provide many of the beneficial effects of TCA with a superior side effect profile...
A different type of procedure for a different type of painMichael C Hsu
Arthritis Rheum 54:3725-7. 2006
A twin study of posttraumatic stress disorder symptoms and chronic widespread painLester M Arguelles
Division of Epidemiology and Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL, USA
Pain 124:150-7. 2006..Future research is needed to understand the temporal association of PTSD and CWP, as well as the physiological underpinnings of this relationship...
Analgesia and hyperalgesia from CRF receptor modulation in the central nervous system of Fischer and Lewis ratsJean-Philippe Vit
Department of Neurological Surgery and the W.M. Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, CA 94143, USA
Pain 121:241-60. 2006..Our results establish that central CRF is a key modulator of pain behavior and indicates that CRF effects on nociception are largely independent of its mood modulating effect as well as its control of the HPA axis...
Cardiac autonomic modulation. Analyzing circadian and ultradian rhythmsPhyllis K Stein
Washington University School of Medicine, St. Louis, MO 63108, USA
IEEE Eng Med Biol Mag 26:14-8. 2007
Ambulatory monitoring of physical activity and symptoms in fibromyalgia and chronic fatigue syndromeWillem J Kop
Department of Medical and Clinical Psychology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA
Arthritis Rheum 52:296-303. 2005....
Sex effects on heart rate variability in fibromyalgia and Gulf War illnessPhyllis K Stein
Washington University School of Medicine, St Louis, MO 63108, USA
Arthritis Rheum 51:700-8. 2004..To investigate autonomic abnormalities in male and female fibromyalgia (FM) and Gulf War illness (GWI) patients by comparing heart rate variability (HRV) with that of age- and sex-matched healthy controls...
Persistent pain and depression: a biopsychosocial perspectiveLisa C Campbell
Pain Prevention and Treatment Program, Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
Biol Psychiatry 54:399-409. 2003....
Characteristic electron microscopic findings in the skin of patients with fibromyalgia: preliminary studySeong Ho Kim
Dongguk University College of Medicine, Gyeongju, South Korea
Clin Rheumatol 27:219-23. 2008..If these findings are replicated in a larger study, these abnormalities may contribute to, or be due to, the lower pain threshold seen in FMS patients...
The management of fibromyalgiaSrinivas G Rao
Cypress Bioscience, San Diego, California 92121, USA
Drugs Today (Barc) 40:539-54. 2004..In addition, nonpharmacological therapies such as aerobic exercise and cognitive behavioral therapy are quite effective and frequently underutilized in clinical practice...
Clinical research into alternative and complementary therapies: how do we tell if the glass is half empty or half full?Daniel J Clauw
J Rheumatol 30:2088-9. 2003
Fibromyalgia: where are we a decade after the American College of Rheumatology classification criteria were developed?Leslie J Crofford
Arthritis Rheum 46:1136-8. 2002
Prevalence of symptoms and symptom-based conditions among Gulf War veterans: current status of research findingsDrue H Barrett
National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA
Epidemiol Rev 24:218-27. 2002
Research Grants
- Michigan Institute for Clinical and Health Research (MICHR) (KL2)Daniel Clauw; Fiscal Year: 2007..Both accelerated options and intensive programs are available. Finally, a robust pilot program will disburse up to $8 million/yr in pilot funds, focusing on stimulating translational and interdisciplinary studies. ..
- The Michigan Clinical Research CollaboratoryDaniel Clauw; Fiscal Year: 2004..Disseminate findings, tools, and strategies from this project to other re-engineered networks and Research Centers, and ultimately interface with a National Electronics Clinical Trials and Research (NECTAR) network...
- CHRONIC LOW BACK PAIN AS A MODEL OF FIBROMYALGIADaniel Clauw; Fiscal Year: 2002..abstract_text> ..
