Duncan Clark

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi request reprint The drinking situations of adolescents treated for alcohol use disorders: a psychometric and alcohol-related outcomes investigation
    Gilbert R Parra
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Addict Behav 30:1725-36. 2005
  2. pmc Providing Alcohol-Related Screening and Brief Interventions to Adolescents through Health Care Systems: Obstacles and Solutions
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
    PLoS Med 7:e1000214. 2010
  3. pmc Mobile phone text message intervention to reduce binge drinking among young adults: study protocol for a randomized controlled trial
    Brian Suffoletto
    Department of Emergency Medicine, University of Pittsburgh, Iroquois Building, Pittsburgh, PA 15261, USA
    Trials 14:93. 2013
  4. pmc Neuroimaging methods for adolescent substance use disorder prevention science
    D B Clark
    School of Medicine and the School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA
    Prev Sci 14:300-9. 2013
  5. doi request reprint Pharmacotherapy for adolescent alcohol use disorder
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
    CNS Drugs 26:559-69. 2012
  6. ncbi request reprint Alcohol use frequency as a screen for alcohol use disorders in adolescents
    Duncan B Clark
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Int J Adolesc Med Health 18:181-7. 2006
  7. pmc Parental supervision and alcohol use in adolescence: developmentally specific interactions
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Dev Behav Pediatr 29:285-92. 2008
  8. ncbi request reprint Childhood risk categories for adolescent substance involvement: a general liability typology
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 77:13-21. 2005
  9. ncbi request reprint Multidimensional assessment of nicotine dependence in adolescents
    Duncan B Clark
    Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 77:235-42. 2005
  10. doi request reprint Introduction to alcohol and adolescent brain development
    Duncan B Clark
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Alcohol Clin Exp Res 32:373-4. 2008

Detail Information

Publications69

  1. ncbi request reprint The drinking situations of adolescents treated for alcohol use disorders: a psychometric and alcohol-related outcomes investigation
    Gilbert R Parra
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Addict Behav 30:1725-36. 2005
    ..These results indicate that the IDS is a reliable and valid measure for use with adolescents receiving treatment for alcohol-related problems...
  2. pmc Providing Alcohol-Related Screening and Brief Interventions to Adolescents through Health Care Systems: Obstacles and Solutions
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
    PLoS Med 7:e1000214. 2010
    b>Duncan Clark and Howard Moss identify obstacles to alcohol-related screening and treatment for adolescents and propose policy solutions.
  3. pmc Mobile phone text message intervention to reduce binge drinking among young adults: study protocol for a randomized controlled trial
    Brian Suffoletto
    Department of Emergency Medicine, University of Pittsburgh, Iroquois Building, Pittsburgh, PA 15261, USA
    Trials 14:93. 2013
    ..Efficacy of SMS programs to reduce binge drinking remains unknown...
  4. pmc Neuroimaging methods for adolescent substance use disorder prevention science
    D B Clark
    School of Medicine and the School of Pharmacy, University of Pittsburgh, Pittsburgh, PA, USA
    Prev Sci 14:300-9. 2013
    ..Further research is needed to provide definitive findings on neurodevelopmental immaturity as an SUD risk and to determine the directions such observations suggest for advancing prevention science...
  5. doi request reprint Pharmacotherapy for adolescent alcohol use disorder
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
    CNS Drugs 26:559-69. 2012
    ....
  6. ncbi request reprint Alcohol use frequency as a screen for alcohol use disorders in adolescents
    Duncan B Clark
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Int J Adolesc Med Health 18:181-7. 2006
    ..These results indicate that an assessment of the frequency of alcohol use in the prior month provides an initial screen with acceptable sensitivity and specificity for use with adolescents...
  7. pmc Parental supervision and alcohol use in adolescence: developmentally specific interactions
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Dev Behav Pediatr 29:285-92. 2008
    ..This study examined the interaction of parental supervision and adolescent alcohol use from late childhood through middle adolescence...
  8. ncbi request reprint Childhood risk categories for adolescent substance involvement: a general liability typology
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 77:13-21. 2005
    ..The findings indicate that these five risk categories constitute general liability classes for adolescent substance involvement, and may identify homogeneous groups of children requiring distinct preventive interventions...
  9. ncbi request reprint Multidimensional assessment of nicotine dependence in adolescents
    Duncan B Clark
    Department of Psychiatry, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 77:235-42. 2005
    ..The findings suggest that the NDSS has acceptable psychometric properties when applied to adolescents, complementing smoking rate and FTND in a multidimensional smoking assessment...
  10. doi request reprint Introduction to alcohol and adolescent brain development
    Duncan B Clark
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Alcohol Clin Exp Res 32:373-4. 2008
  11. doi request reprint Alcohol, psychological dysregulation, and adolescent brain development
    Duncan B Clark
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Alcohol Clin Exp Res 32:375-85. 2008
    ..This article will describe some of the opportunities contemporary neuroimaging techniques offer for advancing understanding of adolescent neurodevelopment and alcohol involvement...
  12. pmc Child abuse and other traumatic experiences, alcohol use disorders, and health problems in adolescence and young adulthood
    Duncan B Clark
    Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 1521, USA
    J Pediatr Psychol 35:499-510. 2010
    ..We prospectively examined the health effects of child abuse and other traumatic events, with objective health indicators and consideration of alcohol use disorders (AUD)...
  13. ncbi request reprint Supervisory neglect and adolescent alcohol use disorders: effects on AUD onset and treatment outcome
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Addict Behav 30:1737-50. 2005
    ..Utilizing a four-item supervision scale, this study identified adolescents with inadequate supervision, and examined effects on AUD development and treatment outcome...
  14. pmc Adolescent-onset substance use disorders predict young adult mortality
    Duncan B Clark
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Adolesc Health 42:637-9. 2008
    ..Adolescent SUDs, as well as gender, ethnic group, hazardous substance use, and drug trafficking, predicted these deaths. Among African American males with SUDs, 23% died by age 25...
  15. pmc Screening and brief intervention for underage drinkers
    Duncan B Clark
    Division of Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Mayo Clin Proc 85:380-91. 2010
    ..Nevertheless, advances in clinical methods and progress on reimbursement policies have made screening and brief intervention for underage drinking more feasible in general health care practice...
  16. ncbi request reprint Fluoxetine for the treatment of childhood anxiety disorders: open-label, long-term extension to a controlled trial
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 44:1263-70. 2005
    ..To assess the efficacy of fluoxetine for the long-term treatment of children and adolescents with anxiety disorders, including generalized anxiety disorder, separation anxiety disorder, and/or social phobia...
  17. ncbi request reprint Substance use disorder trajectory classes: diachronic integration of onset age, severity, and course
    Duncan B Clark
    Center for Education and Drug Abuse Research, University of Pittsburgh, and Western Psychiatric Institute and Clinic, PA 15213, USA
    Addict Behav 31:995-1009. 2006
    ..This article illustrates the utilization of SAS-TRAJ mixture modeling to characterize variations in SUD symptom trajectories to define phenotypes...
  18. ncbi request reprint The natural history of adolescent alcohol use disorders
    Duncan B Clark
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Addiction 99:5-22. 2004
    ..To examine clinically relevant research on the development, course and outcomes of adolescence alcohol use disorders (AUDs)...
  19. ncbi request reprint Neurobehavioral disinhibition in childhood predicts early age at onset of substance use disorder
    Ralph E Tarter
    University of Pittsburgh, Department of Pharmaceutical Sciences, Pittsburgh, PA 15261, USA
    Am J Psychiatry 160:1078-85. 2003
    ....
  20. doi request reprint The illustration-based Assessment of Liability and EXposure to Substance use and Antisocial behavior for children
    Ty A Ridenour
    University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Drug Alcohol Abuse 35:242-52. 2009
    ....
  21. ncbi request reprint Acute phase and five-year follow-up study of fluoxetine in adolescents with major depression and a comorbid substance use disorder: a review
    Jack R Cornelius
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 30:1824-33. 2005
    ..However, the long-term clinical course for the Major Depression of that comorbid adolescent population is surprisingly poor...
  22. pmc Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liability
    Michael M Vanyukov
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA 15261, USA
    Behav Genet 39:233-44. 2009
    ..The data suggest a high heritability of the index in males. The results suggest applicability of the method for genetic and other etiology-related research, and for evaluation of individual risk...
  23. ncbi request reprint Treatment of co-occurring alcohol, drug, and psychiatric disorders
    Jack R Cornelius
    School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213 2593, USA
    Recent Dev Alcohol 17:349-65. 2005
    ..This chapter also identifies gaps in knowledge regarding the treatment of comorbid adolescents, and outlines directions for future research in this field...
  24. ncbi request reprint Major depression associated with earlier alcohol relapse in treated teens with AUD
    Jack R Cornelius
    Department of Psychiatry, Western Psychiatric Institute, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Addict Behav 29:1035-8. 2004
    ..27, df=1, P=.039). These results suggest that the comorbid presence of MDD is associated with an earlier relapse to alcohol use among adolescents with an AUD...
  25. pmc Prospective study of the association between abandoned dwellings and testosterone level on the development of behaviors leading to cannabis use disorder in boys
    Ralph E Tarter
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, School of Pharmacy, Pittsburgh, PA 15261, USA
    Biol Psychiatry 65:116-21. 2009
    ..It was theorized that adverse neighborhood correlates with testosterone level that in turn potentiates behaviors predisposing to cannabis consumption and subsequently diagnosis of cannabis use disorder...
  26. doi request reprint Relation among HPA and HPG neuroendocrine systems, transmissible risk and neighborhood quality on development of substance use disorder: results of a 10-year prospective study
    Ralph E Tarter
    Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, University of Pittsburgh, 3520 Forbes Avenue, Parkvale Annex, 2nd Floor, Pittsburgh, PA 15213, United States
    Drug Alcohol Depend 127:226-31. 2013
    ....
  27. pmc Gender differences in the relationship between white matter organization and adolescent substance use disorders
    Dawn L Thatcher
    University of Pittsburgh, School of Medicine, Department of Psychiatry, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 110:55-61. 2010
    ..These findings suggest that the disruption of normal white matter development due to substance exposure may be more severe in females than in males...
  28. ncbi request reprint Serum tryptophan ratio and suicidal behavior in adolescents: a prospective study
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Psychiatry Res 119:199-204. 2003
    ..This finding suggests that the tryptophan ratio may improve the identification of adolescents at high risk for suicidal behavior...
  29. pmc Double-blind fluoxetine trial in comorbid MDD-CUD youth and young adults
    Jack R Cornelius
    Department of Psychiatry, University of Pittsburgh School of Medicine, PAARC Suite, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 112:39-45. 2010
    ..We hypothesized that fluoxetine would demonstrate efficacy versus placebo for the treatment of the depressive symptoms and the cannabis use of adolescents and young adults with comorbid MDD/CUD...
  30. pmc Premature mortality among males with substance use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 33:156-60. 2008
    ..The objective of this study was to assess whether the presence of SUD or ASP is associated with early mortality among males (fathers) in a predominantly community sample, using a 15-year prospective longitudinal study design...
  31. ncbi request reprint Predictors of marijuana use in adolescents before and after licit drug use: examination of the gateway hypothesis
    Ralph E Tarter
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, PA 15261, USA
    Am J Psychiatry 163:2134-40. 2006
    ..They also evaluated the accuracy of the "gateway sequence" (illicit drug use following licit drugs) for predicting a diagnosis of substance use disorder...
  32. pmc PTSD contributes to teen and young adult cannabis use disorders
    Jack R Cornelius
    Center for Education and Drug Abuse Research, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 35:91-4. 2010
    ..This study addresses the effect of PTSD on CUD among teenagers transitioning to young adulthood...
  33. pmc Double-blind placebo-controlled trial of fluoxetine in adolescents with comorbid major depression and an alcohol use disorder
    Jack R Cornelius
    University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh PA 15213, USA
    Addict Behav 34:905-9. 2009
    ..We hypothesized that fluoxetine would demonstrate efficacy versus placebo for the treatment of both the depressive symptoms and the drinking of comorbid MDD/AUD adolescents...
  34. pmc Cannabis withdrawal is common among treatment-seeking adolescents with cannabis dependence and major depression, and is associated with rapid relapse to dependence
    Jack R Cornelius
    Department of Psychiatry, University of Pittsburgh School of Medicine, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 33:1500-5. 2008
    ..These findings suggest that cannabis withdrawal should be included as a diagnosis in the upcoming DSM-V, and should be listed in the upcoming criteria list for the DSM-V diagnostic category of cannabis dependence...
  35. doi request reprint Cannabis withdrawal predicts severity of cannabis involvement at 1-year follow-up among treated adolescents
    Tammy Chung
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Addiction 103:787-99. 2008
    ..This study contrasted the concurrent and predictive validity of three operational definitions of cannabis withdrawal in a sample of treated adolescents...
  36. ncbi request reprint Concurrent change in alcohol and drug problems among treated adolescents over three years
    Tammy Chung
    Western Psychiatric Institute and Clinic Pittsburgh Adolescent Alcohol Research Center, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    J Stud Alcohol Drugs 69:420-9. 2008
    ....
  37. pmc Husbands' SUD is associated with higher levels of co-occurring but not non-co-occurring psychiatric disorders among their wives
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Addict Behav 33:1231-4. 2008
    ..We hypothesized that the presence of SUDs among males would be associated with a higher level of SUDs, of co-occurring psychiatric disorders, and of non-co-occurring psychiatric disorders in their wives...
  38. ncbi request reprint Cardiovascular risk factors in adolescents with alcohol use disorders
    Dawn L Thatcher
    Western Psychiatric Institute and Clinic, University of Pittsburgh, PA 15213, USA
    Int J Adolesc Med Health 18:151-7. 2006
    ..Interventions focusing on health behaviors in conjunction with addiction treatment might help improve long-term health outcomes in adolescents with AUDs...
  39. ncbi request reprint Alcohol and drug use and related disorders: An underrecognized health issue among adolescents and young adults attending sexually transmitted disease clinics
    Robert L Cook
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 33:565-70. 2006
    ....
  40. ncbi request reprint Dental abnormalities in children of fathers with substance use disorders
    Jack R Cornelius
    School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Addict Behav 29:979-82. 2004
    ..The data from this study provide evidence that paternal SUDs (HAR vs. LAR status) is associated with poor dental condition, poor oral hygiene, a greater need for dental treatment, and inadequate levels of dental treatment utilization...
  41. ncbi request reprint Increased prevalence of herpes simplex virus type 2 among adolescent women with alcohol use disorders
    Robert L Cook
    Department of Medicine and the Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Adolesc Health 30:169-74. 2002
    ..To determine the relationship between alcohol use disorders (AUDs) and herpes simplex virus type 2 (HSV-2), hepatitis B virus (HBV), and human immunodeficiency virus (HIV) infections among a sample of sexually active adolescents...
  42. ncbi request reprint Childhood psychopathology and adolescent cigarette smoking: a prospective survival analysis in children at high risk for substance use disorders
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Addict Behav 29:837-41. 2004
    ..Through the identification of childhood characteristics predicting daily cigarette smoking in adolescence, these results may facilitate targeting of early childhood preventive interventions...
  43. pmc Psychopathology risk transmission in children of parents with substance use disorders
    Duncan B Clark
    Center for Education and Drug Abuse Research, University of Pittsburgh, PA 15213, USA
    Am J Psychiatry 161:685-91. 2004
    ..This study examined the distinct influences of parent substance use disorder and other psychopathology in the transmission of the risk for psychopathology to their children...
  44. ncbi request reprint Clinical practices in the pharmacological treatment of comorbid psychopathology in adolescents with alcohol use disorders
    Duncan B Clark
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    J Subst Abuse Treat 25:293-5. 2003
    ..The treatment setting did not significantly influence antidepressant prescribing practices. The common and increasing use of psychiatric medications in this population emphasizes the urgent need for empirically based clinical guidelines...
  45. ncbi request reprint Psychiatric disorders and attempted suicide among adolescents with substance use disorders
    Thomas M Kelly
    Pittsburgh Adolescent Alcohol Research Center, School of Medicine, University of Pittsburgh, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 73:87-97. 2004
    ..To determine the effects of psychiatric disorders on attempted suicide among adolescents with substance use disorders (SUD)...
  46. ncbi request reprint Psychiatric disorders among older adolescents treated in emergency departments on weekends: a comparison with a matched community sample
    Thomas M Kelly
    Pittsburgh Adolescent Alcohol Research Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, Pennsylvania 15213, USA
    J Stud Alcohol 64:616-22. 2003
    ....
  47. ncbi request reprint Fluoxetine for the treatment of childhood anxiety disorders
    Boris Birmaher
    Department of Child Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Am Acad Child Adolesc Psychiatry 42:415-23. 2003
    ..To assess the efficacy and tolerability of fluoxetine for the acute treatment of children and adolescents with generalized anxiety disorder, separation anxiety disorder, and/or social phobia...
  48. ncbi request reprint Physical and sexual abuse, depression and alcohol use disorders in adolescents: onsets and outcomes
    Duncan B Clark
    Department of Psychiatry and Pharmaceutical Sciences, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Drug Alcohol Depend 69:51-60. 2003
    ..These results indicate that MDD among adolescents with AUD may be partly attributable to PS Abuse...
  49. ncbi request reprint Measuring risks and outcomes in substance use disorders prevention research
    Duncan B Clark
    J Consult Clin Psychol 70:1207-23. 2002
    ..Comprehensive diachronic evaluation over critical developmental periods provides the technical foundation for etiology and intervention research...
  50. ncbi request reprint Alcohol use disorders in adolescents: epidemiology, diagnosis, psychosocial interventions, and pharmacological treatment
    Duncan B Clark
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Paediatr Drugs 4:493-502. 2002
    ..In this population, pharmacological interventions require further investigation and, where indicated, are generally considered to be supplementary to psychosocial approaches...
  51. ncbi request reprint Adolescent neglect and alcohol use disorders in two-parent families
    Duncan B Clark
    University of Pittsburgh, USA
    Child Maltreat 9:357-70. 2004
    ..Among adolescents receiving treatment for AUDs, those in the Neglect group showed more improvement during a 1-year follow-up period. The results indicate that inadequate parent involvement may be a form of neglect...
  52. pmc Alcohol screening in young persons attending a sexually transmitted disease clinic. Comparison of AUDIT, CRAFFT, and CAGE instruments
    Robert L Cook
    Division of General Internal Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Gen Intern Med 20:1-6. 2005
    ....
  53. ncbi request reprint Is there an association between alcohol consumption and sexually transmitted diseases? A systematic review
    Robert L Cook
    Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Sex Transm Dis 32:156-64. 2005
    ..The objective of this study was to conduct a systematic review of published literature on the association between problematic alcohol consumption and sexually transmitted diseases (STDs)...
  54. pmc Predicting risky drinking outcomes longitudinally: what kind of advance notice can we get?
    Robert A Zucker
    Department of Psychiatry, University of Michigan Addiction Research Center, Ann Arbor, Michigan 48105, USA
    Alcohol Clin Exp Res 30:243-52. 2006
    ..b>Duncan Clark and Jack Cornelius follow with a report on the predictive utility of parental disruptive behavior disorders in ..
  55. ncbi request reprint Fluoxetine in adolescents with comorbid major depression and an alcohol use disorder: a 3-year follow-up study
    Jack R Cornelius
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 30:807-14. 2005
    ..The high rate of MDD at follow-up suggests that longer term antidepressant medication treatment may be needed for at least some comorbid adolescents...
  56. ncbi request reprint Adolescent alcohol use disorders predict adult borderline personality
    Dawn L Thatcher
    Pittsburgh Adolescent Alcohol Research Center PAARC, Department of Psychiatry, University of Pittsburgh Medical Center, USA
    Addict Behav 30:1709-24. 2005
    ..This study investigated adolescent alcohol use disorders (AUDs) and other characteristics as predictors of adult borderline personality disorder (BPD) symptoms...
  57. ncbi request reprint Alcohol and psychiatric comorbidity
    Jack R Cornelius
    Pittsburgh Adolescent Alcohol Research Center, Center for Education and Drug Abuse Research, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Recent Dev Alcohol 16:361-74. 2003
    ..However, controlled treatment studies involving alcoholics with other comorbid disorders are almost totally lacking. Consequently, to date, no empirically proven treatment exists for most of these comorbid disorders...
  58. ncbi request reprint Early age of first sexual intercourse and affiliation with deviant peers predict development of SUD: a prospective longitudinal study
    Jack R Cornelius
    Center for Education and Drug Abuse Research CEDAR, University of Pittsburgh, 3811 O Hara Street, PAARC Suite, Pittsburgh, PA 15213, USA
    Addict Behav 32:850-4. 2007
    ..The objective of this study was to assess whether early onset of sexual intercourse and affiliation with deviant peers serve as predictors of the development of SUD, using a prospective longitudinal study design...
  59. ncbi request reprint Rapid relapse generally follows treatment for substance use disorders among adolescents
    Jack R Cornelius
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, 3811 O Hara Street, Pittsburgh, PA 15213, USA
    Addict Behav 28:381-6. 2003
    ..1993). In J. S. Baer, G. A. Marlatt, & R. J. McMahon (Eds.), Addictive behaviors across the life span (pp. 160-183). London: SAGE.] in showing that most adolescents relapse quickly following treatment for substance use disorders...
  60. ncbi request reprint Liability to substance use disorders: 1. Common mechanisms and manifestations
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Neurosci Biobehav Rev 27:507-15. 2003
    ..An accompanying paper describes an approach to the quantitative estimation of this trait...
  61. ncbi request reprint Fluoxetine in depressed AUD adolescents: a 1-year follow-up evaluation
    Jack R Cornelius
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Child Adolesc Psychopharmacol 14:33-8. 2004
    ..1998) and the significant levels of drinking of our comorbid adolescents suggest that longer term treatment may be needed for at least some adolescents with major depressive disorder and alcohol use disorder...
  62. ncbi request reprint Testosterone levels and sexual maturation predict substance use disorders in adolescent boys: a prospective study
    Maureen D Reynolds
    Center for Education and Drug Abuse Research, University of Pittsburgh School of Pharmacy, Pittsburgh, Pennsylvania 15261, USA
    Biol Psychiatry 61:1223-7. 2007
    ..This investigation determined whether testosterone level and sexual maturation in boys biased development of socially nonnormative behavior culminating in a substance use disorder (SUD)...
  63. ncbi request reprint Analyzing milestones in smoking cessation: illustration in a nicotine patch trial in adult smokers
    Saul Shiffman
    Department of Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Consult Clin Psychol 74:276-85. 2006
    ..6). The biggest effect of treatment was to prevent progression to relapse among those who had lapsed (HR = 7.1). Analysis of effects by milestones may enhance understanding of cessation treatments and their mechanisms of action...
  64. ncbi request reprint Interventions in suicidal alcoholics
    Jack R Cornelius
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Alcohol Clin Exp Res 28:89S-96S. 2004
    ..Appropriate hospitalization, discharge, and family involvement are discussed. Finally, gaps in knowledge are identified with a focus on priorities and directions for future research...
  65. ncbi request reprint Liability to substance use disorders: 2. A measurement approach
    Michael M Vanyukov
    Department of Pharmaceutical Sciences, Center for Education and Drug Abuse Research, University of Pittsburgh, 707 Salk Hall, Pittsburgh, PA 15261, USA
    Neurosci Biobehav Rev 27:517-26. 2003
    ..This method is also applicable to measuring liabilities to other complex disorders, especially those with relatively late onset...
  66. doi request reprint Brain activation, response inhibition, and increased risk for substance use disorder
    REBECCA L MCNAMEE
    Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
    Alcohol Clin Exp Res 32:405-13. 2008
    ..Youth at high risk for developing substance use disorders (SUDs) often exhibit differences which suggest inhibitory impairments when compared to average risk youth...
  67. pmc Different lengths of times for progressions in adolescent substance involvement
    Ty A Ridenour
    The Pennsylvania State University, Prevention Research Center, State College 16801, United States
    Addict Behav 31:962-83. 2006
    ..Females had shorter transition times, though gender differences were small. Some evidence was found for a familial influence on transition times above what was accounted for by differences between substances...
  68. ncbi request reprint Prefrontal cortex, thalamus, and cerebellar volumes in adolescents and young adults with adolescent-onset alcohol use disorders and comorbid mental disorders
    Michael D De Bellis
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA
    Alcohol Clin Exp Res 29:1590-600. 2005
    ....
  69. ncbi request reprint Diary study of substance use and unsafe sex among adolescents with substance use disorders
    Susan L Bailey
    Division of Epidemiology and Biostatistics, University of Illinois, Chicago, Illinois 60612, USA
    J Adolesc Health 38:297.e13-20. 2006
    ..This study tested event-level associations between substance use and condom use, as well as potential covariates, among adolescents with substance use disorders (SUDs)...

Research Grants15

  1. Northwest Pennsylvania Adolescent Alcohol Research Cooperative (Phase II)
    Duncan B Clark; Fiscal Year: 2010
    ..CADSUD requires limited practitioner training and, if proven effective, could be readily disseminated. ..
  2. Northwest Pennsylvania Adolescent Alcohol Research Cooperative
    Duncan Clark; Fiscal Year: 2007
    ..With this project, NPAARC will initiate a long-term partnership among rural health care providers, the Center for Rural Health Care Practice, and the Pittsburgh Adolescent Alcohol Research Center. ..
  3. ADOLESCENT PSYCHOPATHOLOGY AND ALCOHOL USE DISORDERS
    Duncan Clark; Fiscal Year: 2007
    ..abstract_text> ..
  4. Drug Addiction Transitions from Adolesence to Adulthood
    Duncan Clark; Fiscal Year: 2004
    ....
  5. Drug Addiction Transitions from Adolesence to Adulthood
    Duncan Clark; Fiscal Year: 2002
    ....
  6. Drug Addiction Transitions from Adolesence to Adulthood
    Duncan Clark; Fiscal Year: 2003
    ....
  7. Drug Addiction Transitions from Adolesence to Adulthood
    Duncan Clark; Fiscal Year: 2002
    ....
  8. Drug Addiction Transitions from Adolesence to Adulthood
    Duncan Clark; Fiscal Year: 2005
    ....
  9. Neurodevelopmental Maturation and Alcohol Use in Adolescents
    Duncan Clark; Fiscal Year: 2007
    ..Neural circuits known to be involved in psychological regulation and reward responses are hypothesized to be particularly vulnerable to alcohol effects and will be assessed with innovative neuroimaging methods. ..
  10. Frontal White Matter, Executive Function and Treatment Outcome in Adolescent AUDs
    Duncan Clark; Fiscal Year: 2007
    ..abstract_text> ..
  11. Drug Addiction Transitions from Adolesence to Adulthood
    Duncan Clark; Fiscal Year: 2001
    ....