Aaron J Clark

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi Cervical spinal stenosis and sports-related cervical cord neurapraxia
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 31:E7. 2011
  2. pmc Na⁺/K⁺-ATPase β2-subunit (AMOG) expression abrogates invasion of glioblastoma-derived brain tumor-initiating cells
    Matthew Z Sun
    Corresponding Author Andrew T Parsa, MD, PhD, Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94117
    Neuro Oncol 15:1518-31. 2013
  3. doi Gross total resection improves overall survival in children with choroid plexus carcinoma
    Matthew Z Sun
    Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA, 94117, USA
    J Neurooncol 116:179-85. 2014
  4. doi Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma
    Matthew Z Sun
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA, 94117, USA
    J Neurooncol 120:353-60. 2014
  5. doi A systematic review of treatment outcomes in pediatric patients with intracranial ependymomas
    Tene A Cage
    Department of Neurological Surgery, University of California San Francisco, CA 94143, USA
    J Neurosurg Pediatr 11:673-81. 2013
  6. pmc Proportional upregulation of CD97 isoforms in glioblastoma and glioblastoma-derived brain tumor initiating cells
    Michael Safaee
    Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 10:e0111532. 2015
  7. doi Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas
    Michael E Ivan
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    J Neurooncol 121:53-61. 2015
  8. pmc PI3K pathway inhibitors: potential prospects as adjuncts to vaccine immunotherapy for glioblastoma
    Taemin Oh
    Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Feinberg School of Medicine, 676 N St Clair Street, Suite 2210, Chicago, IL 60611 2911, USA
    Immunotherapy 6:737-53. 2014
  9. doi Survival impact of time to initiation of chemoradiotherapy after resection of newly diagnosed glioblastoma
    Matthew Z Sun
    Department of Neurological Surgery, University of California, San Francisco, California and
    J Neurosurg 122:1144-50. 2015
  10. doi A systematic review of the results of surgery and radiotherapy on tumor control for pediatric craniopharyngioma
    Aaron J Clark
    Department of Neurological Surgery, Pediatric Neurosurgery, University of California, San Francisco, San Francisco, CA 94143 0112, USA
    Childs Nerv Syst 29:231-8. 2013

Collaborators

Detail Information

Publications25

  1. doi Cervical spinal stenosis and sports-related cervical cord neurapraxia
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 31:E7. 2011
    ..Treatment is usually supportive, but in adults with focal cervical lesions or instability, surgery is an option. Surgery for neurapraxia in children is rarely indicated...
  2. pmc Na⁺/K⁺-ATPase β2-subunit (AMOG) expression abrogates invasion of glioblastoma-derived brain tumor-initiating cells
    Matthew Z Sun
    Corresponding Author Andrew T Parsa, MD, PhD, Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94117
    Neuro Oncol 15:1518-31. 2013
    ....
  3. doi Gross total resection improves overall survival in children with choroid plexus carcinoma
    Matthew Z Sun
    Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA, 94117, USA
    J Neurooncol 116:179-85. 2014
    ..027), the effect did not meet our criteria for significance in our multivariate Cox model (p = 0.120). GTR improved OS of pediatric CPC and is recommended if it can be safely performed. ..
  4. doi Effects of adjuvant chemotherapy and radiation on overall survival in children with choroid plexus carcinoma
    Matthew Z Sun
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA, 94117, USA
    J Neurooncol 120:353-60. 2014
    ..291, p = 0.027). Both chemotherapy alone and combined chemo-radiation improved OS independent of age, gender, tumor location and extent of resection, while radiation alone did not...
  5. doi A systematic review of treatment outcomes in pediatric patients with intracranial ependymomas
    Tene A Cage
    Department of Neurological Surgery, University of California San Francisco, CA 94143, USA
    J Neurosurg Pediatr 11:673-81. 2013
    ....
  6. pmc Proportional upregulation of CD97 isoforms in glioblastoma and glioblastoma-derived brain tumor initiating cells
    Michael Safaee
    Department of Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 10:e0111532. 2015
    ..Given its proven roles in tumor invasion, expression among aggressive genetic subtypes of GBM, and association with overall survival, CD97 is an attractive therapeutic target for patients with GBM. ..
  7. doi Epidermal growth factor-like module containing mucin-like hormone receptor 2 expression in gliomas
    Michael E Ivan
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    J Neurooncol 121:53-61. 2015
    ....
  8. pmc PI3K pathway inhibitors: potential prospects as adjuncts to vaccine immunotherapy for glioblastoma
    Taemin Oh
    Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Feinberg School of Medicine, 676 N St Clair Street, Suite 2210, Chicago, IL 60611 2911, USA
    Immunotherapy 6:737-53. 2014
    ..This will help determine if these inhibitors are truly a therapeutic avenue with a strong future in GBM immunotherapy...
  9. doi Survival impact of time to initiation of chemoradiotherapy after resection of newly diagnosed glioblastoma
    Matthew Z Sun
    Department of Neurological Surgery, University of California, San Francisco, California and
    J Neurosurg 122:1144-50. 2015
    ....
  10. doi A systematic review of the results of surgery and radiotherapy on tumor control for pediatric craniopharyngioma
    Aaron J Clark
    Department of Neurological Surgery, Pediatric Neurosurgery, University of California, San Francisco, San Francisco, CA 94143 0112, USA
    Childs Nerv Syst 29:231-8. 2013
    ..Treatment strategies range from aggressive resection to planned limited resection combined with adjuvant therapies. Currently there is no consensus for standard of care for pediatric craniopharyngioma...
  11. doi CD97 is a multifunctional leukocyte receptor with distinct roles in human cancers (Review)
    Michael Safaee
    Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Int J Oncol 43:1343-50. 2013
    ..In this review, we will discuss the structure and function of this receptor, with a specific focus on its mechanistic significance in neoplastic diseases. ..
  12. pmc Stable luciferase expression does not alter immunologic or in vivo growth properties of GL261 murine glioma cells
    Aaron J Clark
    The Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, CA 505 Parnassus Ave, Room 779 M, San Francisco, CA, 94143 0112, USA
    J Transl Med 12:345. 2014
    ..However, tumor modification for luciferase has the potential for evoking host immune response against otherwise syngeneic tumor cells, thereby mitigating the tumor cells' value for tumor immunology and immunotherapy studies...
  13. pmc Immunocompetent murine models for the study of glioblastoma immunotherapy
    Taemin Oh
    Department of Neurological Surgery, Northwestern University, Feinberg School of Medicine, 676 N, St, Clair St, Suite 2210, Chicago, IL 60611 2922, USA
    J Transl Med 12:107. 2014
    ....
  14. doi Tuberculoma of the central nervous system
    Arthur R Delance
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, Room 779M, San Francisco, CA 94143 0112, USA
    J Clin Neurosci 20:1333-41. 2013
    ..This review synthesizes pertinent findings in the literature surrounding central nervous system tuberculoma in an effort to highlight recent advances in pathophysiology, diagnosis, and treatment...
  15. doi Tumor control after surgery for spinal myxopapillary ependymomas: distinct outcomes in adults versus children: a systematic review
    William B Feldman
    Department of Neurological Surgery, University of California, San Francisco, California
    J Neurosurg Spine 19:471-6. 2013
    ..Treatment generally consists of resection with or without adjuvant radiotherapy. Evidence-based guidelines for surgical management are lacking due to the rarity of this tumor...
  16. pmc Overexpression of CD97 confers an invasive phenotype in glioblastoma cells and is associated with decreased survival of glioblastoma patients
    Michael Safaee
    Department of Neurological Surgery, University of California San Francisco, San Francisco, California, USA
    PLoS ONE 8:e62765. 2013
    ..This phenotype may explain the discrepancy in survival between high and low CD97-expressing tumors. This data provides impetus for further studies to determine its viability as a therapeutic target in the treatment of GBM...
  17. doi Socioeconomic factors associated with pituitary apoplexy
    Arman Jahangiri
    Department of Neurological Surgery and California Center for Pituitary Disorders, University of California, San Francisco, California
    J Neurosurg 119:1432-6. 2013
    ..The association between pituitary apoplexy and socioeconomic factors that may limit access to health care has not been examined in prior studies...
  18. doi Endoscopic surgery for tuberculum sellae meningiomas: a systematic review and meta-analysis
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco 505 Parnassus Ave Rm M779, San Francisco, CA 94143 0112, USA
    Neurosurg Rev 36:349-59. 2013
    ..Long-term follow-up will be needed to define recurrence rates of EEA as compared to transcranial approaches. Cautious use of EEA for the removal of smaller tuberculum sellae meningiomas after formal endoscopic training may be warranted...
  19. doi Falcine and parasagittal chondrosarcomas
    Michael Safaee
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, Room 779M, San Francisco, CA 94143 0112, USA
    J Clin Neurosci 20:1232-6. 2013
    ..Treatment should be tailored to the biology of the tumor, with radiation therapy reserved for patients with the mesenchymal subtype. ..
  20. doi Results of the AANS membership survey of adult spinal deformity knowledge: impact of training, practice experience, and assessment of potential areas for improved education: Clinical article
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California
    J Neurosurg Spine 21:640-7. 2014
    ..Adult spinal deformity (ASD) surgery is increasing in the spinal neurosurgeon's practice...
  21. doi Intraoperative neuromonitoring with MEPs and prediction of postoperative neurological deficits in patients undergoing surgery for cervical and cervicothoracic myelopathy
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurg Focus 35:E7. 2013
    ..We evaluated the efficacy of IONM in cervical and cervicothoracic spondylotic myelopathy (CSM) cases...
  22. doi Surgical outcomes in choroid plexus papillomas: an institutional experience
    Michael Safaee
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Ave, San Francisco, CA 94117, USA
    J Neurooncol 113:117-25. 2013
    ..This modern experience at a tertiary care center performed exclusively during the MRI-era demonstrates that CPPs can be safely removed with minimal morbidity and good tumor control...
  23. doi Proximal junctional kyphosis and failure after spinal deformity surgery: a systematic review of the literature as a background to classification development
    Darryl Lau
    Department of Neurological Surgery, University of California, San Francisco Department of Neurological Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL University of Nevada, School of Medicine, Las Vegas, NV Silicon Valley Spine Institute, Campbell, CA Norwich Orthopedic Group, North Franklin, CT Private Practice, Amarillo, TX Bronson HealthCare Midwest Spine and Scoliosis Specialists, Kalamazoo, MI Instituto de Patologia da Coluna, Sao Paulo, Brazil Otto von Guericke Universität Magdeburg, Magdeburg, Germany College of Medicine, Kyung Hee University, Seoul, South Korea Chirurgia del Rachide, Padova, Italy Cedars Sinai Medical Center, Los Angeles, CA Royal North Shore Hospital, University of Sydney, Sydney, Australia Oregon Health and Science University, Portland, OR and Hey Clinic, Raleigh, NC
    Spine (Phila Pa 1976) 39:2093-102. 2014
    ..Systematic review of literature...
  24. doi Treatment-related morbidity and the management of pediatric craniopharyngioma: a systematic review
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg Pediatr 10:293-301. 2012
    ..Currently, there is controversy regarding the extent, timing, and modality of treatment for pediatric craniopharyngioma...
  25. doi Intractable episodic bradycardia resulting from progressive lead traction in an epileptic child with a vagus nerve stimulator: a delayed complication
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    J Neurosurg Pediatr 9:389-93. 2012
    ..When placing a VNS unit in a very young child, accommodations must be made for years of expected growth. Delayed intractable bradycardia can result from a vagus nerve under traction by tethered stimulator leads...