Aaron J Clark

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Primary brain T-cell lymphoma of the lymphoblastic type presenting as altered mental status
    Aaron J Clark
    Deparment of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Acta Neurochir (Wien) 152:163-8. 2010
  2. doi Effect of WT1 gene silencing on the tumorigenicity of human glioblastoma multiforme cells
    Aaron J Clark
    Department of Anatomy and Neurobiology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298 0631, USA
    J Neurosurg 112:18-25. 2010
  3. pmc Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression
    Mike Y Chen
    Department of Neurosurgery, Virginia Commonwealth University, Medical College of Virginia Hospitals, Virginia Commonwealth University Health System, P O Box 980631, Richmond, VA 23298 0631, USA
    J Neurooncol 103:87-102. 2011
  4. ncbi Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status
    Aaron J Clark
    Department of Anatomy and Neurobiology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298 0631, USA
    J Neurosurg 107:586-92. 2007
  5. ncbi Down-regulation of Wilms' tumor 1 expression in glioblastoma cells increases radiosensitivity independently of p53
    Aaron J Clark
    Department of Neurosurgery, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298 0631, USA
    J Neurooncol 83:163-72. 2007

Collaborators

Detail Information

Publications5

  1. pmc Primary brain T-cell lymphoma of the lymphoblastic type presenting as altered mental status
    Aaron J Clark
    Deparment of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, VA, USA
    Acta Neurochir (Wien) 152:163-8. 2010
    ..Since treatable, it deserves consideration in patients with altered mental status and imaging abnormalities that include diffuse, non-enhancing changes with increased signal on T2-weighted images...
  2. doi Effect of WT1 gene silencing on the tumorigenicity of human glioblastoma multiforme cells
    Aaron J Clark
    Department of Anatomy and Neurobiology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298 0631, USA
    J Neurosurg 112:18-25. 2010
    ..Studies of nonglioma cell lines have demonstrated that WT1 promotes cell proliferation and survival; however, this ability has not been rigorously analyzed in human GBM...
  3. pmc Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression
    Mike Y Chen
    Department of Neurosurgery, Virginia Commonwealth University, Medical College of Virginia Hospitals, Virginia Commonwealth University Health System, P O Box 980631, Richmond, VA 23298 0631, USA
    J Neurooncol 103:87-102. 2011
    ..Counterintuitively, upregulation of IGF-1R was evident after WT1 silencing. In conclusion, WT1 functions as a survival factor in glioblastomas, possibly through inhibition of IGF-1R expression...
  4. ncbi Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status
    Aaron J Clark
    Department of Anatomy and Neurobiology, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, Virginia 23298 0631, USA
    J Neurosurg 107:586-92. 2007
    ..The goal in this study was to characterize the expression pattern of WT1 in human gliomas and to determine if a correlation exists between WT1 expression and p53 status...
  5. ncbi Down-regulation of Wilms' tumor 1 expression in glioblastoma cells increases radiosensitivity independently of p53
    Aaron J Clark
    Department of Neurosurgery, Virginia Commonwealth University, Medical College of Virginia Campus, Richmond, VA 23298 0631, USA
    J Neurooncol 83:163-72. 2007
    ..Anti-WT1 strategies may, therefore, prove useful in improving the response of glioblastoma to radiotherapy, thus potentially improving patient survival...