Research Topics
| Mariann D ChurchwellSummaryAffiliation: University of Toledo Country: USA Publications
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Detail Information
Publications
Daptomycin clearance during modeled continuous renal replacement therapyMariann D Churchwell
The University of Toledo, College of Pharmacy, Department of Pharmacy Practice, Toledo, Ohio, USA
Blood Purif 24:548-54. 2006..Pharmacotherapy in critically ill patients receiving continuous renal replacement therapies (CRRT) is challenging due to the lack of published information to base dosing regimens...
Trace element removal during in vitro and in vivo continuous haemodialysisMariann D Churchwell
Department of Pharmacy Practice, University of Toledo College of Pharmacy, 2801 W Bancroft MS 609, Toledo, OH 43606, USA
Nephrol Dial Transplant 22:2970-7. 2007..Our understanding of trace element CRRT clearance has been limited by poor assay sensitivity. The development of inductively coupled plasma mass spectrometry (ICP-MS) allows for the measurement of CRRT trace element removal...
Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysisMariann D Churchwell
1Department of Pharmacy Practice, University of Toledo College of Pharmacy, Toledo, OH 43606 3360, USA
Nephrol Dial Transplant 24:231-8. 2009..We investigated whether the addition of albumin to dialysate affects dialytic clearance of VPA, CBZ and PHT...
Use of an in vitro model of renal replacement therapy systems to estimate extracorporeal drug removalMariann D Churchwell
University of Toledo College of Pharmacy and Pharmaceutical Sciences, 3000 Arlington Avenue, MS 1013, Toledo, OH, USA
J Clin Pharmacol 52:35S-44S. 2012..This review describes in vitro renal replacement therapy models and compares the findings of several in vitro and in vivo studies...
Drug dosing during continuous renal replacement therapyMariann D Churchwell
Department of Pharmacy Practice, University of Toledo, College of Pharmacy, Toledo, OH, USA
Semin Dial 22:185-8. 2009..This drug dosing review will highlight factors that clinicians should consider when determining a pharmacotherapy regimen for a patient receiving CRRT...
Vibration enhances clearance of solutes with varying molecular weights during in vitro hemodialysisBruce A Mueller
Department of Clinical, Social and Administrative Sciences, College of Pharmacy, University of Michigan, Ann Arbor, MI 48109 1065, USA
ASAIO J 59:140-4. 2013..The addition of vibration during dialysis increased transmembrane clearance for solutes with molecular weights of 60-1450 Daltons...
Selected pharmacokinetic issues in patients with chronic kidney diseaseMariann D Churchwell
Department of Pharmacy Practice, University of Toledo College of Pharmacy, Toledo, Ohio, USA
Blood Purif 25:133-8. 2007..The likelihood of an adverse drug reaction increases with each medication added to these patients' daily regimen. In this article we discuss selected pharmacokinetic issues unique to CKD patients...
